ES2075255T3 - Separacion en enantiomeros de cimaterol. - Google Patents

Separacion en enantiomeros de cimaterol.

Info

Publication number
ES2075255T3
ES2075255T3 ES91106774T ES91106774T ES2075255T3 ES 2075255 T3 ES2075255 T3 ES 2075255T3 ES 91106774 T ES91106774 T ES 91106774T ES 91106774 T ES91106774 T ES 91106774T ES 2075255 T3 ES2075255 T3 ES 2075255T3
Authority
ES
Spain
Prior art keywords
cimaterol
enantiomers
separation
enatiomers
revitalizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91106774T
Other languages
English (en)
Spanish (es)
Inventor
Wolfgang Dr Dipl-Chem Resemann
Adolf Durr
Gunther Prof Dr Engelhardt
John Francis Dr Quirke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Vetmedica GmbH
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Boehringer Ingelheim Vetmedica GmbH
Boehringer Ingelheim Vetmedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica GmbH, Boehringer Ingelheim Vetmedica Inc filed Critical Boehringer Ingelheim Vetmedica GmbH
Application granted granted Critical
Publication of ES2075255T3 publication Critical patent/ES2075255T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Birds (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES91106774T 1990-05-04 1991-04-26 Separacion en enantiomeros de cimaterol. Expired - Lifetime ES2075255T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4014252A DE4014252A1 (de) 1990-05-04 1990-05-04 Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer

Publications (1)

Publication Number Publication Date
ES2075255T3 true ES2075255T3 (es) 1995-10-01

Family

ID=6405664

Family Applications (2)

Application Number Title Priority Date Filing Date
ES91106774T Expired - Lifetime ES2075255T3 (es) 1990-05-04 1991-04-26 Separacion en enantiomeros de cimaterol.
ES93117935T Expired - Lifetime ES2109412T3 (es) 1990-05-04 1991-04-26 (-)-cimaterol en esencia opticamente puro y sus sales por adicion de acidos, asi como su empleo como medicamento o favorecedor del rendimiento.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES93117935T Expired - Lifetime ES2109412T3 (es) 1990-05-04 1991-04-26 (-)-cimaterol en esencia opticamente puro y sus sales por adicion de acidos, asi como su empleo como medicamento o favorecedor del rendimiento.

Country Status (27)

Country Link
US (4) US5248695A (en:Method)
EP (2) EP0455155B1 (en:Method)
JP (1) JP2944777B2 (en:Method)
KR (1) KR0183024B1 (en:Method)
AR (1) AR247728A1 (en:Method)
AT (2) ATE124932T1 (en:Method)
AU (1) AU645313B2 (en:Method)
BG (1) BG60743B1 (en:Method)
CA (1) CA2041818C (en:Method)
CZ (1) CZ286389B6 (en:Method)
DE (3) DE4014252A1 (en:Method)
DK (2) DK0589488T3 (en:Method)
ES (2) ES2075255T3 (en:Method)
FI (1) FI109600B (en:Method)
GR (2) GR3017064T3 (en:Method)
HU (1) HU214335B (en:Method)
ID (1) ID966B (en:Method)
IE (2) IE69017B1 (en:Method)
IL (1) IL98030A (en:Method)
NO (1) NO174803B (en:Method)
NZ (1) NZ238032A (en:Method)
PT (1) PT97544B (en:Method)
RU (1) RU2002737C1 (en:Method)
SG (1) SG45439A1 (en:Method)
SK (1) SK279258B6 (en:Method)
TW (1) TW197415B (en:Method)
ZA (1) ZA913337B (en:Method)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4014252A1 (de) * 1990-05-04 1991-11-07 Boehringer Ingelheim Vetmed Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer
GB9107196D0 (en) * 1991-04-05 1991-05-22 Sandoz Ag Improvements in or relating to organic compounds
GB2289842B (en) * 1991-04-05 1996-01-31 Sepracor Inc Improved use of ß2 bronchodilator drugs
WO1997026871A1 (en) * 1996-01-29 1997-07-31 Savor, Evelyn Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists
US6110974A (en) 1997-04-30 2000-08-29 Bridge Pharma, Inc. Methods of accelerating muscle growth and improving feed efficiency in animals by using optically pure eutomers of adrenergic beta-2 receptor agonists, and food supplements containing the same
EP1787529A3 (en) * 1997-04-30 2009-11-18 Courage Corporation Pty Ltd. Composition and methods using an eutomer
ZA994264B (en) 1998-07-01 2000-01-25 Warner Lambert Co Stereoisomers with high affinity for adrenergic receptors.
RU2201420C2 (ru) * 1998-11-03 2003-03-27 Новартис Аг Нитрилы дипептидов
US7232837B2 (en) 1999-06-29 2007-06-19 Mcneil-Ppc, Inc. Stereoisomers with high affinity for adrenergic receptors
PL362868A1 (en) * 2000-04-27 2004-11-02 Boehringer Ingelheim Pharma Gmbh & Co.Kg Novel, slow-acting betamimetics, a method for their production and their use as medicaments
US20030162459A1 (en) * 2002-02-27 2003-08-28 Osbon Robert Lindsay Method for producing a nonwoven fabric with enhanced characteristics
WO2004103057A2 (en) * 2003-05-15 2004-12-02 The University Of Georgia Research Foundation, Inc. Compositions and methods for inducing adipose tissue cell death
ATE380027T1 (de) 2003-09-09 2007-12-15 Fumapharm Ag Verwendung von fumarsäure-derivaten zur behandlung von herzinsuffizienz und asthma
SG124283A1 (en) * 2004-03-24 2006-08-30 Trusted Hub Ltd Document signature method & system
CN101203214B (zh) * 2005-04-13 2012-11-21 艾升制药公司 用于治疗皮肤结缔组织疾病的β2-肾上腺素受体激动剂
WO2006128180A2 (en) * 2005-05-27 2006-11-30 Children's Medical Center Corporation Methods for the treatment of disease
WO2006138243A2 (en) * 2005-06-13 2006-12-28 University Of Vermont And State Agricultural College Inhibition of creatine uptake to promote weight loss
RU2408014C2 (ru) * 2009-03-10 2010-12-27 Государственное образовательное учреждение высшего профессионального образования "Российский государственный медицинский университет им. Н.И. Пирогова Министерства здравоохранения и социального развития Российской Федерации" Способ прогнозирования преждевременных родов инфекционного генеза
MX368898B (es) 2012-12-03 2019-10-21 Pfizer Moduladores selectivos del receptor de androgenos novedosos.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL136601C (en:Method) * 1967-06-15
US4119710A (en) * 1972-12-18 1978-10-10 Boehringer Ingelheim Gmbh Bronchospasmolytic 1-(p-amino-phenyl)-2-amino-ethanols-(1) and salts
US4407819A (en) * 1980-08-25 1983-10-04 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for the depression of fat deposition in warm blooded animals
US4814350A (en) * 1986-09-10 1989-03-21 American Cyanamid Company Method of treating diabetes with 5-[1-hydroxy-2-(isopropylamino)ethyl]anthranilonitrile
US4792546A (en) * 1986-12-05 1988-12-20 American Cyanamid Company Method for increasing weight gains and reducing deposition of fat in animals
DE4014252A1 (de) * 1990-05-04 1991-11-07 Boehringer Ingelheim Vetmed Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer

Also Published As

Publication number Publication date
DK0455155T3 (da) 1995-11-13
US5395957A (en) 1995-03-07
JP2944777B2 (ja) 1999-09-06
DE4014252A1 (de) 1991-11-07
ZA913337B (en) 1993-01-27
DK0589488T3 (da) 1998-05-04
CZ286389B6 (cs) 2000-03-15
CS129291A3 (en) 1991-11-12
BG94342A (en) 1994-06-30
ATE124932T1 (de) 1995-07-15
CA2041818A1 (en) 1991-11-05
IE80651B1 (en) 1998-11-04
US5648386A (en) 1997-07-15
ID966B (id) 1996-09-30
AU645313B2 (en) 1994-01-13
NO911746L (no) 1991-11-05
HUT60999A (en) 1992-11-30
ATE158277T1 (de) 1997-10-15
EP0589488B1 (de) 1997-09-17
NO174803B (no) 1994-04-05
GR3025547T3 (en) 1998-03-31
KR0183024B1 (ko) 1999-05-15
RU2002737C1 (ru) 1993-11-15
BG60743B1 (bg) 1996-02-29
JPH04225944A (ja) 1992-08-14
KR910019966A (ko) 1991-12-19
PT97544A (pt) 1992-01-31
HU214335B (hu) 1998-03-02
SK279258B6 (sk) 1998-08-05
GR3017064T3 (en) 1995-11-30
DE59105957D1 (de) 1995-08-17
DE59108853D1 (de) 1997-10-23
AU7611191A (en) 1991-11-07
ES2109412T3 (es) 1998-01-16
NZ238032A (en) 1996-02-27
US5248695A (en) 1993-09-28
EP0455155A1 (de) 1991-11-06
US5292753A (en) 1994-03-08
CA2041818C (en) 2003-02-11
IL98030A (en) 1995-12-31
IE69017B1 (en) 1996-07-24
PT97544B (pt) 1998-08-31
HU911502D0 (en) 1991-11-28
IE911507A1 (en) 1991-11-06
NO911746D0 (no) 1991-05-03
FI109600B (fi) 2002-09-13
EP0589488A1 (de) 1994-03-30
FI912151L (fi) 1991-11-05
FI912151A0 (fi) 1991-05-03
TW197415B (en:Method) 1993-01-01
SG45439A1 (en) 1998-01-16
IL98030A0 (en) 1992-06-21
AR247728A1 (es) 1995-03-31
NO174803C (en:Method) 1994-07-13
EP0455155B1 (de) 1995-07-12

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