ES2067854T3 - Polisulfato de derivado de ciclodextrina y procedimiento para preparar el mismo. - Google Patents
Polisulfato de derivado de ciclodextrina y procedimiento para preparar el mismo.Info
- Publication number
- ES2067854T3 ES2067854T3 ES91302039T ES91302039T ES2067854T3 ES 2067854 T3 ES2067854 T3 ES 2067854T3 ES 91302039 T ES91302039 T ES 91302039T ES 91302039 T ES91302039 T ES 91302039T ES 2067854 T3 ES2067854 T3 ES 2067854T3
- Authority
- ES
- Spain
- Prior art keywords
- polysulphate
- preparing
- procedure
- same
- cyclodextrin derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical class O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title abstract 3
- 229920000858 Cyclodextrin Polymers 0.000 abstract 2
- 230000000798 anti-retroviral effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
- C08B30/18—Dextrin, e.g. yellow canari, white dextrin, amylodextrin or maltodextrin; Methods of depolymerisation, e.g. by irradiation or mechanically
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
Abstract
SE PRESENTA UN POLISULFATO DE UNA CICLODEXTRINA EN EL CUAL AL MENOS UNA DE ENTRE 6 Y 8 UNIDADES DE GLUCOSA-D QUE CONSTITUYEN LA CICLODEXTRINA HAN SIDO REEMPLAZADAS POR UNA UNIDAD REPRESENTADA POR LA FORMULA (I) EN LA QUE R ES UN GRUPO REPRESENTADO POR LA FORMULA: EN LA QUE R SUB 1 A R SUB 7 ESTAN DEFINIDAS EN LAS ESPECIFICACIONES; DICHO POLISULFATO TIENE UNA EXCELENTE ACTIVIDAD ANTIRETROVIRUS, PARTICULARMENTE UNA EXCELENTE ACTIVIDAD INHIBIDORA DE PROLIFERACION CONTRA EL HIV
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6592590 | 1990-03-15 | ||
JP6592490A JPH03265601A (ja) | 1990-03-15 | 1990-03-15 | β―シクロデキストリンスルホネート誘導体のポリ硫酸エステル及びその製法 |
JP6592690 | 1990-03-15 | ||
JP25925890 | 1990-09-27 | ||
JP25925790A JPH04136001A (ja) | 1990-09-27 | 1990-09-27 | β―シクロデキストリン・スルホンアミド誘導体のポリ硫酸エステル及びその製法 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2067854T3 true ES2067854T3 (es) | 1995-04-01 |
Family
ID=27523950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91302039T Expired - Lifetime ES2067854T3 (es) | 1990-03-15 | 1991-03-12 | Polisulfato de derivado de ciclodextrina y procedimiento para preparar el mismo. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5250520A (es) |
EP (1) | EP0447171B1 (es) |
KR (1) | KR910016773A (es) |
AT (1) | ATE113612T1 (es) |
CA (1) | CA2038254A1 (es) |
DE (1) | DE69104877T2 (es) |
DK (1) | DK0447171T3 (es) |
ES (1) | ES2067854T3 (es) |
GR (1) | GR3014906T3 (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5658894A (en) * | 1989-04-23 | 1997-08-19 | The Trustees Of The University Of Pennsylvania | Compositions for inhibiting restenosis |
US5760015A (en) * | 1988-01-19 | 1998-06-02 | The Trustees Of The University Of Pennsylvania | Cyclodextrin compounds and methods of making and use thereof |
US5637575A (en) * | 1988-01-19 | 1997-06-10 | The Trustees Of The University Of Pennsylvania | Methods of inhibiting restenosis |
US5441944A (en) * | 1989-04-23 | 1995-08-15 | The Trustees Of The University Of Pennsylvania | Substituted cyclodextrin sulfates and their uses as growth modulating agents |
JP2556236B2 (ja) * | 1991-08-29 | 1996-11-20 | 田辺製薬株式会社 | β−シクロデキストリン誘導体のポリ硫酸エステル及びその製法 |
JPH05279381A (ja) * | 1991-09-13 | 1993-10-26 | Dainippon Ink & Chem Inc | 硫酸化オリゴ糖芳香族配糖体 |
US5446030A (en) * | 1991-09-19 | 1995-08-29 | Weisz; Paul B. | Prevention of hemolysis |
BR9405858A (pt) * | 1993-03-31 | 1995-12-12 | Univ Pennsylvania | Processos de afetar o crescimento de tecido vivo em mamiferos compostos e composiçÕes para os mesmos |
JPH11100401A (ja) * | 1997-07-30 | 1999-04-13 | Kikkoman Corp | 環状オリゴ糖及びそれを含むレトロウイルス性疾患の予防または治療剤 |
DE19814815C2 (de) * | 1998-04-02 | 2000-10-12 | Gerhard Steffan | Sterinverknüpfte, anionische Cyclodextrinderivate und deren Verwendung in Arzneimittelformulierungen |
JP4782334B2 (ja) | 1999-08-13 | 2011-09-28 | ナームローゼ・フエンノートチヤツプ・オルガノン | 薬物起因性神経筋遮断のための拮抗薬としての化学的キレート化剤の使用 |
TWI242015B (en) * | 1999-11-29 | 2005-10-21 | Akzo Nobel Nv | 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
FR2811572B1 (fr) * | 2000-07-17 | 2003-04-18 | Adir | Utilisation de cyclodextrines polysulfatees pour le traitement de l'arthrose |
ES2269504T3 (es) * | 2000-11-02 | 2007-04-01 | Akzo Nobel N.V. | Uso de agentes complejantes con cortisol en cuadros de tratamimento de transtornos relacionados con hipercortisolemia. |
US20050209189A1 (en) * | 2001-03-06 | 2005-09-22 | Roger Hershline | Antiviral composition |
US6821958B1 (en) * | 2001-03-06 | 2004-11-23 | Roger K. Hershline | Antiviral composition |
GB0220198D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Modified saccharides,conjugates thereof and their manufacture |
US20050059634A1 (en) * | 2003-07-28 | 2005-03-17 | Venton Duane L. | Per-6-substituted-per-6-deoxy-cyclodextrins, and use of the same to inhibit soluble beta-amyloid-peptide derived oligomers and to treat alzheimer's and related diseases |
WO2006001844A2 (en) * | 2004-01-29 | 2006-01-05 | Pinnacle Pharmaceuticals | β-CYCLODEXTRIN DERIVATIVES AND THEIR USE AGAINST ANTHRAX LETHAL TOXIN |
US20080234182A1 (en) * | 2007-03-22 | 2008-09-25 | Innovative Biologics, Inc. | Blockers of pore-forming virulence factors and their use as anti-infectives |
JP2008528761A (ja) * | 2005-01-28 | 2008-07-31 | ピナクル ファーマシューティカルズ,インク. | 抗菌剤としてのβ−シクロデキストリン誘導体 |
JP4905724B2 (ja) * | 2008-05-23 | 2012-03-28 | 国立大学法人宇都宮大学 | シクロデキストリン誘導体 |
US11097023B1 (en) | 2020-07-02 | 2021-08-24 | Par Pharmaceutical, Inc. | Pre-filled syringe containing sugammadex |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3974274A (en) * | 1972-12-23 | 1976-08-10 | Tanabe Seiyaku Co., Ltd. | Process for preparing a cyclodextrin derivative |
US4020160A (en) * | 1975-08-15 | 1977-04-26 | American Cyanamid Company | Cyclodextrin sulfate salts as complement inhibitors |
US4066829A (en) * | 1976-07-12 | 1978-01-03 | American Cyanamid Company | Malto-dextrin poly(H-)sulfates |
US4258180A (en) * | 1979-11-05 | 1981-03-24 | American Cyanamid Company | C6-Modified cyclodextrin sulfate salts as complement inhibitors |
EP0147685B1 (de) * | 1983-12-17 | 1989-04-26 | Hoechst Aktiengesellschaft | Ether des beta-Cyclodextrins und ein Verfahren zu ihrer Herstellung |
US4783446A (en) * | 1985-11-22 | 1988-11-08 | Neushul Mariculture Incorporated | Method for the treatment of AIDS virus and other retroviruses |
JPS6345223A (ja) * | 1986-04-04 | 1988-02-26 | Ueno Seiyaku Oyo Kenkyusho:Kk | ひと免疫不全ウイルス性疾患処置剤 |
EP0240098A3 (en) * | 1986-04-04 | 1989-05-10 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Oligo and polysaccharides for the treatment of diseases caused by retroviruses |
JPS6425724A (en) * | 1987-03-31 | 1989-01-27 | Ueno Seiyaku Oyo Kenkyujo Kk | Suppressant against retrovirus |
MY129863A (en) * | 1988-03-11 | 2007-05-31 | Ishihara Sangyo Kaisha | Biocidal composition |
ATE129897T1 (de) * | 1988-07-07 | 1995-11-15 | Univ Pennsylvania | Modulation von virus-wirtszell-wechselwirkungen unter verwendung von cyclischen oligosacchariden. |
-
1991
- 1991-03-12 ES ES91302039T patent/ES2067854T3/es not_active Expired - Lifetime
- 1991-03-12 DE DE69104877T patent/DE69104877T2/de not_active Expired - Fee Related
- 1991-03-12 DK DK91302039.2T patent/DK0447171T3/da active
- 1991-03-12 AT AT91302039T patent/ATE113612T1/de not_active IP Right Cessation
- 1991-03-12 EP EP91302039A patent/EP0447171B1/en not_active Expired - Lifetime
- 1991-03-13 US US07/668,634 patent/US5250520A/en not_active Expired - Fee Related
- 1991-03-14 CA CA002038254A patent/CA2038254A1/en not_active Abandoned
- 1991-03-15 KR KR1019910004164A patent/KR910016773A/ko not_active Application Discontinuation
-
1995
- 1995-02-01 GR GR940403896T patent/GR3014906T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK0447171T3 (da) | 1994-12-12 |
GR3014906T3 (en) | 1995-05-31 |
KR910016773A (ko) | 1991-11-05 |
CA2038254A1 (en) | 1991-09-16 |
ATE113612T1 (de) | 1994-11-15 |
US5250520A (en) | 1993-10-05 |
DE69104877D1 (de) | 1994-12-08 |
EP0447171A3 (en) | 1992-02-26 |
EP0447171A2 (en) | 1991-09-18 |
EP0447171B1 (en) | 1994-11-02 |
DE69104877T2 (de) | 1995-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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