ES2040278T3 - Soluciones de mezcla de micelas con inhibidores de inflamacion no esteroideos. - Google Patents

Soluciones de mezcla de micelas con inhibidores de inflamacion no esteroideos.

Info

Publication number
ES2040278T3
ES2040278T3 ES198888101411T ES88101411T ES2040278T3 ES 2040278 T3 ES2040278 T3 ES 2040278T3 ES 198888101411 T ES198888101411 T ES 198888101411T ES 88101411 T ES88101411 T ES 88101411T ES 2040278 T3 ES2040278 T3 ES 2040278T3
Authority
ES
Spain
Prior art keywords
micella
mixing solutions
inflammation inhibitors
steroid
steroid inflammation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888101411T
Other languages
English (en)
Inventor
Alberto Dr. Ferro
Hans Dr. Steffen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2040278T3 publication Critical patent/ES2040278T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

DISOLUCIONES ACUOSAS DE MICELA ALEADA DE SALES DE ACIDO BILIAR Y LIPIDOS PUEDEN UTILIZARSE PARA SOLUBILIZACION DE INHIBIDORES DE INFLAMACION NO ESTEROIDALES Y PARA FABRICACION DE FORMAS DE SUMINISTRO PARENTERAL COMPATIBLE LOCALMENTE PARA TALES MEDICAMENTOS.
ES198888101411T 1987-02-03 1988-02-01 Soluciones de mezcla de micelas con inhibidores de inflamacion no esteroideos. Expired - Lifetime ES2040278T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH38087 1987-02-03

Publications (1)

Publication Number Publication Date
ES2040278T3 true ES2040278T3 (es) 1993-10-16

Family

ID=4185694

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888101411T Expired - Lifetime ES2040278T3 (es) 1987-02-03 1988-02-01 Soluciones de mezcla de micelas con inhibidores de inflamacion no esteroideos.

Country Status (13)

Country Link
US (1) US4882164A (es)
EP (1) EP0280887B1 (es)
JP (1) JP2645427B2 (es)
AT (1) ATE71288T1 (es)
AU (1) AU599198B2 (es)
CA (1) CA1319886C (es)
DE (1) DE3867502D1 (es)
DK (1) DK175662B1 (es)
ES (1) ES2040278T3 (es)
IE (1) IE61068B1 (es)
NZ (1) NZ223290A (es)
PH (1) PH24848A (es)
ZA (1) ZA88562B (es)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3903753A1 (de) * 1989-02-06 1990-08-23 Schering Ag Verfahren zur herstellung waessriger mischmicelloesungen
NZ232865A (en) * 1989-03-21 1992-07-28 Hoffmann La Roche A mixed-micelle solution comprising a micelle former and an immunomodulator
AU6461090A (en) * 1989-10-30 1991-05-02 Abbott Laboratories Injectable formulation for lipophilic drugs
US5085864A (en) * 1989-10-30 1992-02-04 Abbott Laboratories Injectable formulation for lipophilic drugs
DE3938030A1 (de) * 1989-11-13 1991-05-16 Schering Ag Verfahren zur herstellung waessriger mischmicelloesungen
CA2033725C (en) * 1990-01-24 2001-05-29 Folker Pittrof Pharmaceutical and cosmetic compositions containing a salt of cholanic acid
US5009895A (en) * 1990-02-02 1991-04-23 Merck & Co., Inc. Sustained release with high and low viscosity HPMC
JP3249147B2 (ja) * 1990-06-01 2002-01-21 キリン−アムジエン・インコーポレーテツド 生理活性蛋白含有経口製剤
FR2663224B1 (fr) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa Forme galenique parenterale.
FR2715846A1 (fr) * 1994-02-07 1995-08-11 Rhone Poulenc Rorer Sa Nouvelle composition pharmceutique à base de taxoïdes.
JP2740153B2 (ja) * 1995-03-07 1998-04-15 エフ・ホフマン−ラ ロシユ アーゲー 混合ミセル
DE19522693A1 (de) * 1995-06-22 1997-01-02 Dianorm G Maierhofer Gmbh Zusammensetzung zur Herstellung feindisperser Systeme und Verfahren zu ihrer Herstellung
US5891472A (en) * 1996-11-19 1999-04-06 Meri Charmyne Russell Treatment of equine laminitis
GB9625589D0 (en) 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
DZ2479A1 (fr) * 1997-05-05 2003-02-01 Pfizer Composés inhibiteurs sélectifs de cox-2 anti-inflammatoires et compositions pharmaceutiques les contenant.
AU773615B2 (en) * 1997-05-05 2004-05-27 Pfizer Inc. COX-2 selective carprofen for treating pain and inflammation in dogs
US20030212123A1 (en) * 1997-05-05 2003-11-13 Pfizer Inc. COX-2 selective carprofen for treating pain and inflammation in dogs
CH692322A5 (it) 1997-05-26 2002-05-15 Westy Ag Formulazione iniettabile limpida di Propofol.
WO1999043301A1 (en) * 1998-02-24 1999-09-02 The Board Of Trustees Of The University Of Illinois Lipid emulsions in the treatment of systemic poisoning
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
SE0100901D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab New composition
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US20030190343A1 (en) * 2002-03-05 2003-10-09 Pfizer Inc. Palatable pharmaceutical compositions for companion animals
GB0207529D0 (en) * 2002-04-02 2002-05-08 Norbrook Lab Ltd Injectable veterinary composition for small animals
AU2003100262B4 (en) * 2003-04-07 2003-09-18 Jurox Pty Ltd Stable carprofen composition
EP1651187A4 (en) * 2003-07-31 2009-03-11 Univ Texas STERILE PREPARATIONS OF PHOSPHOLIPIDES AND ANTI-INFLAMMATORY PHARMACEUTICALS AND MANUFACTURING AND USE METHOD
NZ567601A (en) * 2005-11-30 2010-12-24 Generex Pharm Inc Orally absorbed pharmaceutical formulation and method of administration
US8703204B2 (en) 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
WO2008135828A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
KR100785656B1 (ko) 2007-05-14 2007-12-17 재단법인서울대학교산학협력재단 소염제로 사용되는 소디움글리코콜레이트 또는 그 유도체
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
WO2008149192A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
EP2240162A4 (en) 2007-12-06 2013-10-09 Bend Res Inc NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER
WO2009073215A1 (en) 2007-12-06 2009-06-11 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
FI2504353T4 (fi) 2009-11-23 2023-11-30 Cubist Pharmaceuticals Llc Lipopeptidikoostumukset ja vastaavat menetelmät
WO2013081120A1 (ja) * 2011-11-30 2013-06-06 学校法人日本大学 レシチンオルガノゲル形成剤
EP2857043B1 (en) 2012-05-31 2019-01-23 Terumo Kabushiki Kaisha pH-SENSITIVE CARRIER AND METHOD FOR PRODUCTION THEREOF, pH-SENSITIVE MEDICINE AND pH-SENSITIVE PHARMACEUTICAL COMPOSITION EACH CONTAINING SAID CARRIER, AND CULTURE METHOD USING SAID pH-SENSITIVE MEDICINE OR SAID pH-SENSITIVE PHARMACEUTICAL COMPOSITION
JP6487850B2 (ja) * 2013-11-29 2019-03-20 テルモ株式会社 アジュバント組成物およびこれを含むワクチン組成物、並びにこれらの製造方法
US20170035701A1 (en) * 2015-08-04 2017-02-09 Taipei Medical University Stabilized high drug load nanocarriers, methods for their preparation and use thereof
US9937147B2 (en) 2015-10-29 2018-04-10 NBDD, Inc. Edible base product composition
WO2018129345A1 (en) 2017-01-08 2018-07-12 Resq Pharma, Inc. Methods for decreasing injuries associated with intraoperative hypotension
CN110169951A (zh) * 2019-05-17 2019-08-27 河北远征药业有限公司 一种兽用卡洛芬注射液及其制备方法和应用
CN110025575A (zh) * 2019-05-24 2019-07-19 安徽奥力欣生物科技有限公司 一种替米考星混合胶束可溶性粉及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE610853A (es) * 1960-12-05
US3896145A (en) * 1972-07-24 1975-07-22 Hoffmann La Roche Carbazoles
IT1202370B (it) * 1976-07-12 1989-02-09 Hoffmann La Roche Soluzioni inietabili in cui l'atti vita' emolitica degli agenti di formazione di micelle naturali e' evitata mediante l'aggiunta di lipoidi e relativi prodotti
US4328222A (en) * 1978-11-21 1982-05-04 Hoffmann-La Roche Inc. Pharmaceutical compositions for parenteral or local administration
GR73668B (es) * 1978-11-21 1984-03-28 Hoffmann La Roche
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
FR2453711A1 (fr) * 1979-04-14 1980-11-07 Hanning Elektro Werke Machine servant a aiguiser des outils et des instruments tranchants ou d'autres objets a meuler
DE3221579A1 (de) * 1982-06-08 1983-12-22 Eckert, Theodor, Prof. Dr., 4400 Münster Solubilisierung von in wasser schwerloeslichen wirkstoffen in waessrige loesung unter verwendung eines gemisches von cholinphosphorsaeureglycerindiester (cholin-lecithin) und natriumdesoxycholat als loesungsvermittler und die therapeutische verwendung der so erhaltenen waessrigen loesungen
IL72420A (en) * 1983-07-22 1987-10-30 Hoffmann La Roche Aqueous vitamin e solutions and their manufacture
CA1264162A (en) 1984-03-15 1990-01-02 Manfred Breuninger Glycerol ether phosphatides
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung

Also Published As

Publication number Publication date
IE61068B1 (en) 1994-09-21
IE880279L (en) 1988-08-03
EP0280887B1 (de) 1992-01-08
DK175662B1 (da) 2005-01-10
NZ223290A (en) 1990-11-27
AU599198B2 (en) 1990-07-12
ATE71288T1 (de) 1992-01-15
DK4088D0 (da) 1988-01-06
ZA88562B (en) 1988-08-03
JPS63201133A (ja) 1988-08-19
US4882164A (en) 1989-11-21
AU1076688A (en) 1988-08-04
EP0280887A1 (de) 1988-09-07
DE3867502D1 (de) 1992-02-20
DK4088A (da) 1988-08-04
JP2645427B2 (ja) 1997-08-25
PH24848A (en) 1990-12-26
CA1319886C (en) 1993-07-06

Similar Documents

Publication Publication Date Title
ES2040278T3 (es) Soluciones de mezcla de micelas con inhibidores de inflamacion no esteroideos.
ES2052645T3 (es) Acidos poliinsaturados con accion vasocinetica y formulaciones farmaceuticas y cosmeticas que los contienen.
ES2103563T3 (es) Esteres nitricos con una actividad farmacologica y procedimiento para su preparacion.
IT1164548B (it) Forme galeniche di somministrazione di medicamenti per via orale,a liberazione programmata,e loro procedimenti di preparazione
BG47033A3 (en) Method for preparing of derivatives of imidazolamine
DE3774148D1 (de) Im magen verbleibende granula.
ES2167910T3 (es) Parches oleosos para uso externo que contienen diclofenaco sodico.
DE69033856D1 (de) Verabreichungssystem für phospholipide
ES2059965T3 (es) Un procedimiento para preparar una composicion farmaceutica para el tratamiento de enfermedades inflamatorias.
TW282393B (es)
ES546840A0 (es) Un procedimiento para preparar una sal de acido n-acetil- neuraminico
IT1303671B1 (it) Sali dell'acido nitrico con farmaci attivi nel trattamento dipatologie del sistema respiratorio
ES2033483T3 (es) Derivados de acido alquenoico
NO20002649D0 (no) Anvendelse av en blanding av diol og en alfa-hydroksysyre for behandling av hyperkeratotiske hudsykdommer
BG43692A3 (en) Method for preparing of 6, 16- dimethylcorticoids
ES2167329T3 (es) Cristal de hidrato de derivado de acido quinolonacarboxilico.
FI911207A (fi) Menetelmä uuden terapeuttisesti käyttökelpoisen retinoidin valmistamiseksi
ES2163147T3 (es) Perfeccionamientos de agentes antimicrobianos de accion prolongada o relativos a los mismos.
MX163682B (es) Proceso para la produccion de alfa-amilasa estable en solucion y alfa-amilasa liquida producida por el mismo
ES2129654T3 (es) Dosificacion directa del colesterol.
ES2059737T3 (es) Sulfonanilidas anti-hipertensoras.
KR940006600A (ko) 혈전용해의 활성을 가지는 의약품의 제조를 위한 트롬빈의 직접적인 억제제의 이용
ES2063713B1 (es) Ampolla y solucion para infusion de acido tioctico en forma de las sales solubles en agua del acido tioctico.
DE69634203D1 (de) Cis-9,10-octadecenoamidase
ES2005525T3 (es) Procedimiento para la fabricacion de 5-hidroxi-diprafenona y sus sales con acidos.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 280887

Country of ref document: ES