ES2039210T3 - Un procedimiento para preparar compuestos heterociclicos. - Google Patents

Un procedimiento para preparar compuestos heterociclicos.

Info

Publication number
ES2039210T3
ES2039210T3 ES198787101043T ES87101043T ES2039210T3 ES 2039210 T3 ES2039210 T3 ES 2039210T3 ES 198787101043 T ES198787101043 T ES 198787101043T ES 87101043 T ES87101043 T ES 87101043T ES 2039210 T3 ES2039210 T3 ES 2039210T3
Authority
ES
Spain
Prior art keywords
group
procedure
cyclic compounds
hetero cyclic
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787101043T
Other languages
English (en)
Inventor
Shiro Terashima
Yoshio Ito
Takeo Kawabata
Kunikazu Sakai
Tamejiro Hiyama
Yoshikazu Kimura
Makoto Sunagawa
Katsumi Tamoto
Akira Sasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharmaceuticals Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Application granted granted Critical
Publication of ES2039210T3 publication Critical patent/ES2039210T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN COMPUESTO DE FORMULA (I) EN LA QUE R1,R2,R3 Y R4 SON CADA UNO DE ELLOS UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO INFERIOR, UN GRUPO ALQUILO INFERIOR-ARILO O UN GRUPO ARILO, O R1 Y R2 PUEDEN SER COMBINADOS CONJUNTAMENTE PARA FORMAR UN GRUPO ALQUILENO INFERIOR Y/O R3 Y R4 SON COMBINADOS CONJUNTAMENTE PARA FORMAR UN GRUPOALQUILENO INFERIOR, O R1 Y R2, R3 Y R4 PUEDEN COMBINARSE UNOS CON OTROS PARA FORMAR UN GRUPO O-FENILENO, X ES UN ATOMO DE HALOGENO E Y ES UN ATOMO DE OXIGENO O UN ATOMO DE NITROGENO SUSTITUIDOS CON UN ALQUILO INFERIOR O ARILO, EL CUAL COMPUESTO ES UTIL COMO COMPUESTO INTERMEDIO EN LA SINTESIS DE COMPUESTOS 1 BETAMETILCARBAPENEM VALIOSOS COMO ANTIBIOTICOS.
ES198787101043T 1986-01-27 1987-01-26 Un procedimiento para preparar compuestos heterociclicos. Expired - Lifetime ES2039210T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1374786 1986-01-27
JP4606086 1986-03-05

Publications (1)

Publication Number Publication Date
ES2039210T3 true ES2039210T3 (es) 1993-09-16

Family

ID=26349587

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787101043T Expired - Lifetime ES2039210T3 (es) 1986-01-27 1987-01-26 Un procedimiento para preparar compuestos heterociclicos.

Country Status (9)

Country Link
EP (1) EP0232786B1 (es)
JP (1) JP2789190B2 (es)
KR (1) KR940008748B1 (es)
DE (1) DE3778049D1 (es)
ES (1) ES2039210T3 (es)
FI (1) FI92059C (es)
GR (1) GR3004335T3 (es)
HU (2) HU199428B (es)
IE (1) IE59138B1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631363A (en) * 1992-11-13 1997-05-20 Tanabe Seiyaku Co., Ltd. Azetidinone compound and process for preparation thereof
US5442055A (en) * 1992-11-13 1995-08-15 Tanabe Seiyaku Co., Ltd. Azetidinone compound and process for preparation thereof
US6011150A (en) * 1992-11-13 2000-01-04 Tanabe Seiyaku Co., Ltd. Azetidinone compound and process for preparation thereof
JP2856913B2 (ja) * 1993-05-18 1999-02-10 宣治 山下 可撓性型枠材及びそれを利用した貫通孔形成工法
US5550229A (en) * 1993-06-23 1996-08-27 Tanabe Seiyaku Co., Ltd. Alkylation process for preparing azetidinone compound and starting compound therefor
IT1391259B1 (it) * 2008-10-28 2011-12-01 Acs Dobfar Spa Derivati 1,3-imidazolidinici e loro utilizzo per la produzione di carbapenem
EP2345645A1 (en) 2009-12-22 2011-07-20 Savior Lifetec Corporation Method for manufacturing stereoselective preparation of 4-bma using a chiral auxiliary and chiral auxiliary
CN102250033A (zh) * 2011-05-27 2011-11-23 菏泽睿智科技开发有限公司 一种合成培南类抗生素的新型手性辅基的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH422743A (de) * 1961-11-10 1966-10-31 Sandoz Ag Verfahren zur Herstellung neuer Phosphorsäureester
GB1482879A (en) * 1975-07-24 1977-08-17 Nippon Chemiphar Co 5-benzyl-2-oxazolidone derivatives and a process for producing the same
JPS6169839A (ja) * 1984-08-24 1986-04-10 Toray Ind Inc 着色エポキシ系球状微粒子
CA1276156C (en) * 1985-03-29 1990-11-13 Thomas N. Salzmann Enantioselective process for producing 1-beta- methylcarbapenem antibiotic intermediates
JPS61275267A (ja) * 1985-03-29 1986-12-05 メルク　エンド　カムパニ−　インコ−ポレ−テツド １−β−メチルカルバペネム抗生物質中間体の鏡像異性選択的製造方法

Also Published As

Publication number Publication date
DE3778049D1 (de) 1992-05-14
KR870007142A (ko) 1987-08-17
FI870315A0 (fi) 1987-01-26
HUT45233A (en) 1988-06-28
FI92059C (fi) 1994-09-26
FI870315A (fi) 1987-07-28
IE870199L (en) 1987-07-27
JP2789190B2 (ja) 1998-08-20
IE59138B1 (en) 1994-01-12
KR940008748B1 (ko) 1994-09-26
HU199428B (en) 1990-02-28
GR3004335T3 (es) 1993-03-31
JPS6310765A (ja) 1988-01-18
EP0232786B1 (en) 1992-04-08
FI92059B (fi) 1994-06-15
HU209952B (en) 1994-12-28
HU895128D0 (en) 1990-03-28
EP0232786A1 (en) 1987-08-19

Similar Documents

Publication Publication Date Title
ES2074441T3 (es) Compuestos espiro heterociclicos y su preparacion.
ES2062501T3 (es) Aditivos de carbamato para composiciones lubricantes.
ATE67493T1 (de) Heterocyclische verbindungen.
ES2120499T3 (es) Derivado de eritromicina.
ES2046271T3 (es) Empleo de derivados de 4-formilaminopiperidina como estabilizantes y material organico estabilizado con ellos.
DE69224212D1 (de) Piperazinderivate als 5-ht1a antagonisten.
CO4990939A1 (es) Derivados de ariletil-(piperidin-4-il metil) amina
ES2039210T3 (es) Un procedimiento para preparar compuestos heterociclicos.
ES2144455T3 (es) Derivado de 1,3-oxazin-4-ona, herbicida que lo contiene, e intermedio nuevo para producirlo.
AR241422A1 (es) Procedimiento para la preparacion de derivados de difenil(metil-etil-0 etenil) piperidinas.
ES2055384T3 (es) Compuestos dioxafosforinanos y composiciones poliolefinicas estabilizadas con ellos.
ES543300A0 (es) Derivados de b-lactama
DE3686232D1 (de) Lactamderivate, deren herstellung und deren benutzung als hypotensive mittel.
ES2037011T3 (es) Procedimiento para la preparacion de nuevos derivados de benzofuran-2-il-imidazol.
ES2076215T3 (es) Nuevos derivados de imidazol.
CR5971A (es) Fenilglicinamida n-sulfonilica y n-sulfinilica
KR850004756A (ko) 4,5,6,7-테트라하이드로 티아졸로[5,4-c]피리딘 유도체의 제조방법
ES2077042T3 (es) Derivados de benzoxazina, derivados de benzotiazina y herbicidas que comprenden los mismos.
ES2088270T3 (es) Derivados alquilicos de la trazodona provistos de actividad sobre el sistema nervioso central.
JPS57209231A (en) N-alkylation of nitrogen-containing organic compound
ES502073A0 (es) Metodo de producir lactamas antihipertensoras
ES2052783T3 (es) Procedimiento para la preparacion de 4-alquil-1,4-dihidropiridinas.
DK0481742T3 (da) Piperazinderivater
CO4870760A1 (es) DERIVADOS DE BENZO [g] QUINOLINA
ES338693A1 (es) Procedimiento para la preparacion de una composicion fungi-cida.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 232786

Country of ref document: ES