ES2036438A1 - Procedimiento para la preparacion del acido 2,2-dimetil-5-(2,5-dimetelfenoxi)-pentanoico y de los productos intermedios para la obtencion del mismo. - Google Patents

Procedimiento para la preparacion del acido 2,2-dimetil-5-(2,5-dimetelfenoxi)-pentanoico y de los productos intermedios para la obtencion del mismo.

Info

Publication number
ES2036438A1
ES2036438A1 ES919101150A ES9101150A ES2036438A1 ES 2036438 A1 ES2036438 A1 ES 2036438A1 ES 919101150 A ES919101150 A ES 919101150A ES 9101150 A ES9101150 A ES 9101150A ES 2036438 A1 ES2036438 A1 ES 2036438A1
Authority
ES
Spain
Prior art keywords
dimethyl
image
intermediates
preparing
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES919101150A
Other languages
English (en)
Other versions
ES2036438B1 (es
Inventor
Zoltan Zubovics
Gabor Feher
Lajos Toldy
Gabor Kovacs
Antal Simay
Eva Kovacs
Imre Moravcsik
Ferenc Szederkenyi
Gyorgy Krasznai
Gyorgyi Vereczkey
Kalman Nagy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES2036438A1 publication Critical patent/ES2036438A1/es
Application granted granted Critical
Publication of ES2036438B1 publication Critical patent/ES2036438B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C07C59/13—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/63—Halogen-containing esters of saturated acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DEL ACIDO 2,2-DIMETIL-5- (2,5-DIMETILFENOXI)-PENTANOICO Y DE LOS PRODUCTOS INTERMEDIOS PARA LA OBTENCION DEL MISMO. EL PROCEDIMIENTO MEJORADO DE PREPARACION DEL ACIDO 2,2-DIMETIL-5-(2,5-DIMETILFENOXI)-PENTANOICO DE LA FORMULA GENERAL (I), CONSISTE EN HACER REACCIONAR UN ESTER DE FORMULA GENERAL (X), EN LA CUAL X ES UN HALOGENO Y Z UN GRUPO ALQUILENO DE CSI1-8 SC DE CADENA LINEAL O RAMIFICADA OPCIONALMENTE SUSTITUIDO POR UNO O DOS GRUPOS 2,2-DIMETIL-5-HELENOPENTANOILOXI, DONDE HALO REPRESENTA CLORO O BROMO, Y EN CUYO GRUPO ALQUILENO UNO O DOS GRUPOS METILENO PUEDEN SUSTITUIRSE OPCIONALMENTE CON HETERO ATOMO(S) O CON UN GRUPO HETEROCICLICO BIVALENTE CON UNA SAL ALCALINA DE 2,5-DIMETILFENO DE FORMULA (II) O CON UN ESTER DE ESTA ULTIMA FORMADO CON UN ACIDO ALCANOICO INFERIOR, E HIDROLIZAR EL ESTER SUSTITUIDO CON ARILOXI DE LA FORMULA GENERAL (XI) ASI OBTENIDO. ADEMAS, LAINVENCION SE REFIERE A COMPUESTOS INTERMEDIOS DE FORMULA GENERAL (X), EN LA QUE X Y Z SON COMO SE HA INDICADO ANTERIORMENTE.
ES09101150A 1990-05-11 1991-05-10 Procedimiento para la preparacion del acido 2,2-dimetil-5-(2,5-dimetelfenoxi)-pentanoico y de los productos intermedios para la obtencion del mismo. Expired - Fee Related ES2036438B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU902997A HU205891B (en) 1990-05-11 1990-05-11 Process for producing 2,2-dimethyl-5-/2,5-dimethyl-phenoxy/-pentanoic acid

Publications (2)

Publication Number Publication Date
ES2036438A1 true ES2036438A1 (es) 1993-05-16
ES2036438B1 ES2036438B1 (es) 1994-05-16

Family

ID=10962060

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09101150A Expired - Fee Related ES2036438B1 (es) 1990-05-11 1991-05-10 Procedimiento para la preparacion del acido 2,2-dimetil-5-(2,5-dimetelfenoxi)-pentanoico y de los productos intermedios para la obtencion del mismo.

Country Status (22)

Country Link
US (1) US5155260A (es)
JP (1) JP2511335B2 (es)
KR (1) KR910019953A (es)
CN (1) CN1032134C (es)
AT (1) AT400716B (es)
BG (1) BG60580B1 (es)
CA (1) CA2042304A1 (es)
CH (1) CH683340A5 (es)
CZ (1) CZ282906B6 (es)
DE (1) DE4115540A1 (es)
DK (1) DK88091A (es)
ES (1) ES2036438B1 (es)
FI (1) FI912303A (es)
FR (1) FR2661908B1 (es)
GB (1) GB2244271B (es)
GR (1) GR1002053B (es)
HU (2) HU205891B (es)
IT (1) IT1253707B (es)
NL (1) NL9100811A (es)
PL (1) PL290204A1 (es)
RU (1) RU2056403C1 (es)
YU (1) YU48481B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5549230B2 (ja) 2010-01-13 2014-07-16 株式会社リコー 測距装置、測距用モジュール及びこれを用いた撮像装置
JP5809390B2 (ja) 2010-02-03 2015-11-10 株式会社リコー 測距・測光装置及び撮像装置
JP5523993B2 (ja) * 2010-08-31 2014-06-18 富士フイルム株式会社 酸ハロゲン化物の製造方法、及び酸ハロゲン化物
HUE21212055T1 (hu) 2011-12-07 2022-11-28 Alnylam Pharmaceuticals Inc Biológiailag lebontható lipidek hatóanyagok bejuttatására

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674836A (en) * 1968-05-21 1972-07-04 Parke Davis & Co 2,2-dimethyl-{11 -aryloxy-alkanoic acids and salts and esters thereof
US4238492A (en) * 1978-05-31 1980-12-09 Societe De Recherches Industrielles S.O.R.I. Phenoxyalkylcarboxylic acids
EP0130077A2 (en) * 1983-06-24 1985-01-02 Yamanouchi Pharmaceutical Co. Ltd. Phenoxy derivatives, their preparation, and pharmaceutical compositions containing them
ES8505633A1 (es) * 1984-07-20 1985-06-01 Valles Rodoreda Enrique Procedimiento para la obtencion del acido 2, 2-dimetil-5(2, 5-xililoxi) valerico
ES8605216A1 (es) * 1985-12-02 1986-03-16 Servicios Y Suministros Farmac Procedimiento para la obtencion del acido 2,2-dimetil-5-(2, 5-dimetil-fenoxi)valerico y sus sales farmaceuticamente aceptables
ES8605217A1 (es) * 1985-12-02 1986-03-16 Servicios Y Suministros Farmac Procedimiento de obtencion del acido 2,2-dimetil-5-(2,5-di- metil-fenoxi)valerico
EP0226161A1 (en) * 1985-12-09 1987-06-24 Warner-Lambert Company Improved process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3759986A (en) * 1970-03-30 1973-09-18 Parke Davis & Co Esters of 2,2-dimethyl-5-(aryloxy)-1-pentanols
US3847994A (en) * 1970-03-30 1974-11-12 Parke Davis & Co 2,2-dimethyl-5-(aryloxy)-valeraldehydes

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3674836A (en) * 1968-05-21 1972-07-04 Parke Davis & Co 2,2-dimethyl-{11 -aryloxy-alkanoic acids and salts and esters thereof
US4238492A (en) * 1978-05-31 1980-12-09 Societe De Recherches Industrielles S.O.R.I. Phenoxyalkylcarboxylic acids
EP0130077A2 (en) * 1983-06-24 1985-01-02 Yamanouchi Pharmaceutical Co. Ltd. Phenoxy derivatives, their preparation, and pharmaceutical compositions containing them
ES8505633A1 (es) * 1984-07-20 1985-06-01 Valles Rodoreda Enrique Procedimiento para la obtencion del acido 2, 2-dimetil-5(2, 5-xililoxi) valerico
ES8605216A1 (es) * 1985-12-02 1986-03-16 Servicios Y Suministros Farmac Procedimiento para la obtencion del acido 2,2-dimetil-5-(2, 5-dimetil-fenoxi)valerico y sus sales farmaceuticamente aceptables
ES8605217A1 (es) * 1985-12-02 1986-03-16 Servicios Y Suministros Farmac Procedimiento de obtencion del acido 2,2-dimetil-5-(2,5-di- metil-fenoxi)valerico
EP0226161A1 (en) * 1985-12-09 1987-06-24 Warner-Lambert Company Improved process for preparing 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid

Also Published As

Publication number Publication date
DK88091D0 (da) 1991-05-10
GR1002053B (en) 1995-11-20
GB2244271A (en) 1991-11-27
DK88091A (da) 1991-11-12
CN1032134C (zh) 1996-06-26
YU48481B (sh) 1998-09-18
KR910019953A (ko) 1991-12-19
FI912303A (fi) 1991-11-12
PL290204A1 (en) 1992-09-21
ES2036438B1 (es) 1994-05-16
CA2042304A1 (en) 1991-11-12
YU81391A (sh) 1993-11-16
CH683340A5 (de) 1994-02-28
GB2244271B (en) 1994-05-11
JPH04226936A (ja) 1992-08-17
HU210180B (en) 1995-02-28
ITMI911290A0 (it) 1991-05-10
CZ282906B6 (cs) 1997-11-12
FI912303A0 (fi) 1991-05-10
AT400716B (de) 1996-03-25
ITMI911290A1 (it) 1992-11-10
IT1253707B (it) 1995-08-23
FR2661908A1 (fr) 1991-11-15
ATA96791A (de) 1995-07-15
JP2511335B2 (ja) 1996-06-26
GR910100202A (el) 1992-07-30
BG60580B1 (bg) 1995-09-29
GB9110157D0 (en) 1991-07-03
US5155260A (en) 1992-10-13
HU902997D0 (en) 1990-09-28
FR2661908B1 (fr) 1995-10-27
NL9100811A (nl) 1991-12-02
DE4115540A1 (de) 1991-11-14
HUT57176A (en) 1991-11-28
CN1056487A (zh) 1991-11-27
CS9101359A2 (en) 1991-11-12
HU205891B (en) 1992-07-28
RU2056403C1 (ru) 1996-03-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000301