ES2012510A6 - Procedimiento para la produccion de derivados de calcitonina - Google Patents

Procedimiento para la produccion de derivados de calcitonina

Info

Publication number
ES2012510A6
ES2012510A6 ES8603267A ES8603267A ES2012510A6 ES 2012510 A6 ES2012510 A6 ES 2012510A6 ES 8603267 A ES8603267 A ES 8603267A ES 8603267 A ES8603267 A ES 8603267A ES 2012510 A6 ES2012510 A6 ES 2012510A6
Authority
ES
Spain
Prior art keywords
radical
alpha
amino acid
aminoacyl
calcitonin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8603267A
Other languages
English (en)
Spanish (es)
Inventor
Francois Cardinaux
Janos Pless
Robert Helmut Buck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES2012510A6 publication Critical patent/ES2012510A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/585Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES8603267A 1985-12-04 1986-12-03 Procedimiento para la produccion de derivados de calcitonina Expired - Lifetime ES2012510A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3542859 1985-12-04
DE3614784 1986-05-02

Publications (1)

Publication Number Publication Date
ES2012510A6 true ES2012510A6 (es) 1990-04-01

Family

ID=25838500

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8603267A Expired - Lifetime ES2012510A6 (es) 1985-12-04 1986-12-03 Procedimiento para la produccion de derivados de calcitonina

Country Status (20)

Country Link
US (1) US4758550A (en:Method)
JP (1) JPH085916B2 (en:Method)
KR (1) KR880006263A (en:Method)
AU (1) AU600242B2 (en:Method)
BE (1) BE905849A (en:Method)
CH (1) CH671229A5 (en:Method)
DK (1) DK580186A (en:Method)
ES (1) ES2012510A6 (en:Method)
FI (1) FI864939A7 (en:Method)
FR (1) FR2590902B1 (en:Method)
GB (1) GB2184729B (en:Method)
GR (1) GR862836B (en:Method)
HU (1) HUT44794A (en:Method)
IL (1) IL80846A0 (en:Method)
IT (1) IT1214754B (en:Method)
LU (1) LU86697A1 (en:Method)
NL (1) NL8602950A (en:Method)
NZ (1) NZ218473A (en:Method)
PT (1) PT83835B (en:Method)
SE (1) SE8605189L (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051647A1 (es) * 1992-12-10 1994-06-16 Lipotec Sa Procedimiento para la preparacion de calcitonina de salmon.

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2052642T3 (es) * 1987-07-08 1994-07-16 Mitsubishi Petrochemical Co Nuevo derivado de calcitonina y su sal.
AU609911B2 (en) * 1987-12-16 1991-05-09 Rorer International (Overseas) Inc. 8-glycine,16-x, des-19-leucine-calcitonin
GB2218102B (en) * 1988-04-08 1992-09-16 Sandoz Ltd Calcitonin peptide derivatives
AU629552B2 (en) * 1988-06-16 1992-10-08 Teijin Limited S-sulfonated calcitonin derivatives
US5026825A (en) * 1988-09-08 1991-06-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Intranasal calcitonin formulations
DE68912090T2 (de) * 1988-11-24 1994-06-16 Mitsubishi Petrochemical Co Calcitonin-Derivate und deren Salze.
FI913899A0 (fi) * 1989-02-23 1991-08-19 Rorer Int Holdings Terapeutiska aerosolblandningar.
US5204326A (en) * 1989-03-16 1993-04-20 Otsuka Pharmaceutical Co., Ltd. Polypeptide derivatives and calcium metabolism improving agent
JP2778249B2 (ja) * 1989-04-21 1998-07-23 株式会社ツムラ 新規生理活性ペプチド類および該ペプチド類を有効成分とするカルシウム代謝調整剤
US5175146A (en) * 1989-12-05 1992-12-29 Vical, Inc. Synthetic calcitonin peptides
US5364840A (en) * 1989-12-05 1994-11-15 Vical, Inc. Synthetic calcitonin peptides
CS89491A3 (en) * 1990-04-09 1992-01-15 Chugai Pharmaceutical Co Ltd Hybrid calcitonin
US5710244A (en) * 1992-12-31 1998-01-20 Labroo; Virender M. Derivatized calcitonins
AU673237B2 (en) * 1992-12-31 1996-10-31 University Of Washington Derivatized calcitonins
WO1995021622A1 (en) * 1994-02-09 1995-08-17 Brigham & Women's Hospital Gel-forming polypeptide derivatives
DE726075T1 (de) * 1995-02-08 1996-12-12 Therapicon Srl Nicht-inorganische pharmazeutische salzige Lösungen zur endonasale Verabreichung
KR960031478A (ko) * 1995-02-14 1996-09-17 성재갑 유비퀴틴 융합 인간 칼시토닌의 정제방법
US6034064A (en) * 1995-04-07 2000-03-07 Hoechst Pharmaceuticals & Chemicals K.K. Peptides and therapeutic agent for autoimmune diseases containing the same
US5721207A (en) * 1995-04-18 1998-02-24 Innapharma, Inc. Method for treatment of pain
US6936584B1 (en) 1998-02-13 2005-08-30 Amylin Pharmaceuticals, Inc. Mixed amylin activity compounds
CA2320962C (en) 1998-02-13 2011-04-19 Amylin Pharmaceuticals, Inc. Novel mixed amylin activity compounds
CA2643826A1 (en) * 2006-02-27 2008-06-12 Paul A. Wender Compositions and methods for transport of molecules with enhanced release properties across biological barriers
CA2855122A1 (en) * 2011-12-09 2013-06-13 The Regents Of The University Of California Modified mini-hepcidin peptides and methods of using thereof
US9816066B2 (en) 2012-04-24 2017-11-14 The Regents Of The University Of California Method for delivery of small molecules and proteins across the cell wall of algae using molecular transporters

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3926938A (en) * 1974-08-12 1975-12-16 Armour Pharma Synthesis of salmon calcitonin
JPS51128993A (en) * 1975-05-01 1976-11-10 Tanpakushitsu Kenkyu Shiyoureikai Process for preparing new polypeptides
GB1592969A (en) * 1976-09-13 1981-07-15 Armour Pharma Hentriacontapeptides and preparation thereof
JPS60500054A (ja) * 1983-02-15 1985-01-17 ア−マ−・フア−マシユ−テイカル・カンパニ− デス−アスパラギン−3−カルシトニン
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
GB8327346D0 (en) * 1983-10-12 1983-11-16 Morris H R Peptide
US4497732A (en) 1983-10-21 1985-02-05 Armour Pharmaceutical Company 1A-Endo-glycine-calcitonin
US4537716A (en) 1983-12-05 1985-08-27 Armour Pharmaceutical Co. Des-serine2 or des-glycine2 -leucine22 calcitonin
US4622386A (en) * 1985-03-28 1986-11-11 Armour Pharmaceutical Company [1,7-di-alanine]calcitonin
US4658014A (en) * 1985-12-20 1987-04-14 Kempe Tomas G Synthetic peptides with calcitonin-like activity
AU7468687A (en) * 1987-06-23 1989-01-05 Armour Pharmaceutical Company (n-acyl, 1,7-di-alanine) calcitonin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051647A1 (es) * 1992-12-10 1994-06-16 Lipotec Sa Procedimiento para la preparacion de calcitonina de salmon.

Also Published As

Publication number Publication date
NZ218473A (en) 1990-03-27
BE905849A (fr) 1987-06-03
LU86697A1 (fr) 1987-07-24
PT83835A (en) 1986-12-01
AU6606186A (en) 1987-06-11
IT1214754B (it) 1990-01-18
FI864939A7 (fi) 1987-06-05
JPH085916B2 (ja) 1996-01-24
NL8602950A (nl) 1987-07-01
JPS62132898A (ja) 1987-06-16
HUT44794A (en) 1988-04-28
CH671229A5 (en:Method) 1989-08-15
IT8648701A0 (it) 1986-12-04
IL80846A0 (en) 1987-03-31
GB2184729A (en) 1987-07-01
DK580186A (da) 1987-06-05
GB8628739D0 (en) 1987-01-07
FI864939A0 (fi) 1986-12-03
FR2590902B1 (fr) 1994-12-23
PT83835B (pt) 1989-06-30
AU600242B2 (en) 1990-08-09
SE8605189D0 (sv) 1986-12-03
SE8605189L (sv) 1987-06-05
GR862836B (en) 1987-04-02
DK580186D0 (da) 1986-12-02
KR880006263A (ko) 1988-07-22
GB2184729B (en) 1990-07-25
US4758550A (en) 1988-07-19
FR2590902A1 (fr) 1987-06-05

Similar Documents

Publication Publication Date Title
ES2012510A6 (es) Procedimiento para la produccion de derivados de calcitonina
YU46023B (sh) Postupak za dobijanje novih analoga insulina
ES2058347T3 (es) Nuevos acidos percarboxilicos imido-aromaticos.
ATE71947T1 (de) Tetrapyrrol-therapiemittel.
ATE121755T1 (de) Deletionsanaloga von magaininpeptiden.
EP0215410A3 (en) Retro-inverso hexapeptide neurotensin analogs, process for their preparation and pharmaceutical compositions containing them
SE9301911D0 (sv) New peptide derivatives
ATE74003T1 (de) Waessriges pharmazeutisches praeparat.
UA35592C2 (uk) Похідні оцтової кислоти
ATE154641T1 (de) Neues physiologisch aktives schweinepeptid (cnp- 53)
ES8400082A1 (es) Procedimiento para la produccion de n-acilo-polipeptidos.
DE3582575D1 (de) Basische zubereitungen von chinoloncarbonsaeuren.
IE781227L (en) New peptide derivatives.
ES8501364A1 (es) Un metodo para la preparacion de nuevos polipeptidos.
ES2012720A6 (es) Procedimiento para la obtencion de sales de adicion de acido de taurina o glicina amidada.
KR910016767A (ko) 신규한 펩티드
GB1502573A (en) Somatostatin analogues
DE69029377D1 (de) Substituierungsanaloge von magaininpeptiden
ES8401930A1 (es) Un procedimiento para preparar derivados de amida del acido nitrobenzoico.
ATE150028T1 (de) Neue ganglioside-derivaten
GB1516515A (en) Process for the preparation of insulin analogues and derivatives thereof
ES437586A1 (es) Procedimiento para la produccion de un peptido.
DK0517778T3 (da) Vasoaktive vasotocinderivater
KR840002346A (ko) 펩타이드의 제조방법
ATE83244T1 (de) Synthese von peptid-aminoalkylamiden und peptid- hydraziden mittels festphasenmethode.