ES2009347A6 - Procedimiento para la preparacion de una composicion farmaceutica. - Google Patents
Procedimiento para la preparacion de una composicion farmaceutica.Info
- Publication number
- ES2009347A6 ES2009347A6 ES8803091A ES8803091A ES2009347A6 ES 2009347 A6 ES2009347 A6 ES 2009347A6 ES 8803091 A ES8803091 A ES 8803091A ES 8803091 A ES8803091 A ES 8803091A ES 2009347 A6 ES2009347 A6 ES 2009347A6
- Authority
- ES
- Spain
- Prior art keywords
- sustained release
- release composition
- biodegradable polyester
- based sustained
- medicinal substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000013268 sustained release Methods 0.000 title abstract 2
- 229920000229 biodegradable polyester Polymers 0.000 title 1
- 239000004622 biodegradable polyester Substances 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
- 229920002988 biodegradable polymer Polymers 0.000 abstract 2
- 239000004621 biodegradable polymer Substances 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- 239000012907 medicinal substance Substances 0.000 abstract 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- YIMQCDZDWXUDCA-UHFFFAOYSA-N [4-(hydroxymethyl)cyclohexyl]methanol Chemical compound OCC1CCC(CO)CC1 YIMQCDZDWXUDCA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA, DESTINADA EN PARTICULAR A LA LIBERACION PROLONGADA Y CONTROLADA DE UNA DOSIS EFICAZ DE SUSTANCIA MEDICAMENTOSA, EN EL QUE SE DISPERSA O SE DISUELVE LA SUSTANCIA MEDICAMENTOSA EN UN SOPORTE QUE CONSISTE EN UN COPOLIMERO O UNA MEZCLA DE POLIMEROS Y/O COPOLIMEROS BIODEGRADABLES DE UN ACIDO DICARBOXILICO ELEGIDO ENTRE LOS ACIDOS DEL CICLO DE KREBS Y DE UN DIOL ALIFATICO QUE CONTIENE 4 ATOMOS DE CARBONO O EL 1,4-CICLOHEXANO-DIMETANOL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH4022/87A CH672887A5 (es) | 1987-10-14 | 1987-10-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2009347A6 true ES2009347A6 (es) | 1989-09-16 |
Family
ID=4268357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8803091A Expired ES2009347A6 (es) | 1987-10-14 | 1988-10-11 | Procedimiento para la preparacion de una composicion farmaceutica. |
Country Status (14)
Country | Link |
---|---|
JP (1) | JP2716747B2 (es) |
BE (1) | BE1001687A5 (es) |
CA (1) | CA1332808C (es) |
CH (1) | CH672887A5 (es) |
DE (1) | DE3835099A1 (es) |
DK (1) | DK571488A (es) |
ES (1) | ES2009347A6 (es) |
FR (1) | FR2622105B1 (es) |
GB (1) | GB2211091B (es) |
GR (1) | GR1000266B (es) |
IE (1) | IE60475B1 (es) |
IT (1) | IT1227394B (es) |
NL (1) | NL8802490A (es) |
PT (1) | PT88757B (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2037621A1 (es) * | 1991-07-22 | 1993-06-16 | Debio Rech Pharma Sa | Procedimiento para la preparacion de microesferas de material polimero biodegradable. |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU221294B1 (en) * | 1989-07-07 | 2002-09-28 | Novartis Ag | Process for producing retarde compositions containing the active ingredient in a polymeric carrier |
CH681425A5 (es) * | 1990-11-14 | 1993-03-31 | Debio Rech Pharma Sa | |
EP0588255A1 (en) * | 1992-09-12 | 1994-03-23 | Dott Limited Company | Physiologically active peptide compositions |
GB9310030D0 (en) * | 1993-05-15 | 1993-06-30 | Scras | Dry processed particles and process for the preparation of the same |
US6440457B1 (en) | 1993-05-27 | 2002-08-27 | Alza Corporation | Method of administering antidepressant dosage form |
FR2777895A1 (fr) | 1998-04-28 | 1999-10-29 | Debio Rech Pharma Sa | Polymere sequence non-reticule,procede pour sa preparation, et ses utilisations |
US20060286138A1 (en) * | 2003-04-10 | 2006-12-21 | Malshe Vinod C | Novel biodegradable aliphatic polyesters and pharmaceutical compositions and applications thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3978203A (en) * | 1974-07-12 | 1976-08-31 | Dynatech Corporation | Sustained release of pharmaceuticals from polyester matrices |
WO1978000011A1 (en) * | 1977-06-07 | 1978-12-21 | Garching Instrumente | Form of implant medicament and preparation process |
US4130639A (en) * | 1977-09-28 | 1978-12-19 | Ethicon, Inc. | Absorbable pharmaceutical compositions based on isomorphic copolyoxalates |
US4186189A (en) * | 1977-09-28 | 1980-01-29 | Ethicon, Inc. | Absorbable pharmaceutical compositions based on poly(alkylene oxalates) |
US4594407A (en) * | 1983-09-20 | 1986-06-10 | Allied Corporation | Prosthetic devices derived from krebs-cycle dicarboxylic acids and diols |
US4481353A (en) * | 1983-10-07 | 1984-11-06 | The Children's Medical Center Corporation | Bioresorbable polyesters and polyester composites |
-
1987
- 1987-10-14 CH CH4022/87A patent/CH672887A5/fr not_active IP Right Cessation
-
1988
- 1988-10-10 GB GB8823735A patent/GB2211091B/en not_active Expired - Fee Related
- 1988-10-11 ES ES8803091A patent/ES2009347A6/es not_active Expired
- 1988-10-11 IT IT8805224A patent/IT1227394B/it active
- 1988-10-11 NL NL8802490A patent/NL8802490A/nl active Search and Examination
- 1988-10-13 PT PT88757A patent/PT88757B/pt active IP Right Grant
- 1988-10-13 IE IE311088A patent/IE60475B1/en not_active IP Right Cessation
- 1988-10-13 FR FR8813487A patent/FR2622105B1/fr not_active Expired - Fee Related
- 1988-10-13 DK DK571488A patent/DK571488A/da not_active Application Discontinuation
- 1988-10-13 GR GR880100688A patent/GR1000266B/el not_active IP Right Cessation
- 1988-10-13 CA CA000579976A patent/CA1332808C/en not_active Expired - Fee Related
- 1988-10-14 JP JP63260364A patent/JP2716747B2/ja not_active Expired - Fee Related
- 1988-10-14 BE BE8801184A patent/BE1001687A5/fr not_active IP Right Cessation
- 1988-10-14 DE DE3835099A patent/DE3835099A1/de not_active Ceased
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2037621A1 (es) * | 1991-07-22 | 1993-06-16 | Debio Rech Pharma Sa | Procedimiento para la preparacion de microesferas de material polimero biodegradable. |
Also Published As
Publication number | Publication date |
---|---|
GB8823735D0 (en) | 1988-11-16 |
DE3835099A1 (de) | 1989-04-27 |
PT88757B (pt) | 1993-01-29 |
DK571488A (da) | 1989-04-15 |
IE883110L (en) | 1989-04-14 |
CA1332808C (en) | 1994-11-01 |
JP2716747B2 (ja) | 1998-02-18 |
GR1000266B (el) | 1992-05-12 |
DK571488D0 (da) | 1988-10-13 |
JPH01157920A (ja) | 1989-06-21 |
IE60475B1 (en) | 1994-07-13 |
BE1001687A5 (fr) | 1990-02-06 |
IT1227394B (it) | 1991-04-08 |
IT8805224A0 (it) | 1988-10-11 |
FR2622105A1 (fr) | 1989-04-28 |
FR2622105B1 (fr) | 1993-05-14 |
GB2211091B (en) | 1991-02-13 |
CH672887A5 (es) | 1990-01-15 |
GB2211091A (en) | 1989-06-28 |
NL8802490A (nl) | 1989-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SA6 | Expiration date (snapshot 920101) |
Free format text: 2008-10-11 |
|
PC1A | Transfer granted |
Owner name: DEBIO RECHERCHE PHARMACEUTIQUE S.A. |