GEP20033012B - Liquid Polymeric Compositions for Controlled Release of Bioactive Substances - Google Patents

Liquid Polymeric Compositions for Controlled Release of Bioactive Substances

Info

Publication number
GEP20033012B
GEP20033012B GEAP19995598A GEAP1999005598A GEP20033012B GE P20033012 B GEP20033012 B GE P20033012B GE AP19995598 A GEAP19995598 A GE AP19995598A GE AP1999005598 A GEAP1999005598 A GE AP1999005598A GE P20033012 B GEP20033012 B GE P20033012B
Authority
GE
Georgia
Prior art keywords
controlled release
polymeric compositions
bioactive substances
liquid polymeric
casing
Prior art date
Application number
GEAP19995598A
Inventor
Joel R Zingerman
Rey T Chern
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of GEP20033012B publication Critical patent/GEP20033012B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

1. Technical Result Preparing liquid composition covered with casing and/or forming incapsulated liquid in the casing. 2. Essence A composition comprises hydrophobic bioactive substance, lactide and glycolide copolymer and a mixture of hydrophilic and lipophilic solvents. 3. Field of Application Medicine.
GEAP19995598A 1998-03-19 1999-03-18 Liquid Polymeric Compositions for Controlled Release of Bioactive Substances GEP20033012B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7957498P 1998-03-19 1998-03-19
GBGB9815801.7A GB9815801D0 (en) 1998-07-21 1998-07-21 Liquid polymeric compositions for controlled released bioactive substances

Publications (1)

Publication Number Publication Date
GEP20033012B true GEP20033012B (en) 2003-07-25

Family

ID=10835852

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP19995598A GEP20033012B (en) 1998-03-19 1999-03-18 Liquid Polymeric Compositions for Controlled Release of Bioactive Substances

Country Status (10)

Country Link
JP (1) JP4829405B2 (en)
AT (1) ATE499069T1 (en)
DE (1) DE69943225D1 (en)
DK (1) DK1484033T3 (en)
GB (1) GB9815801D0 (en)
GE (1) GEP20033012B (en)
PT (1) PT1484033E (en)
RS (1) RS49840B (en)
SI (1) SI1484033T1 (en)
UA (1) UA53788C2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8362086B2 (en) * 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
JP6273252B2 (en) * 2012-03-13 2018-01-31 バイエル・ニュージーランド・リミテッド Long-acting composition
BR112016005589B8 (en) * 2013-09-16 2023-04-18 Merck Sharp & Dohme LIQUID PHARMACEUTICAL COMPOSITION, AND USE THEREOF
KR102101969B1 (en) * 2017-09-06 2020-04-22 (주)인벤티지랩 Microparticles containing moxidectin and method for manufacturing same

Also Published As

Publication number Publication date
SI1484033T1 (en) 2011-06-30
YU54100A (en) 2002-11-15
PT1484033E (en) 2011-04-21
JP4829405B2 (en) 2011-12-07
ATE499069T1 (en) 2011-03-15
GB9815801D0 (en) 1998-09-16
UA53788C2 (en) 2003-02-17
JP2002506797A (en) 2002-03-05
RS49840B (en) 2008-08-07
DK1484033T3 (en) 2011-06-14
DE69943225D1 (en) 2011-04-07

Similar Documents

Publication Publication Date Title
BG104838A (en) Liquid polymeric compositions for controlled release of bioactive substances
MY118835A (en) Sustained release compositions and the process for their preparation
DE69623087D1 (en) Effervescent and its manufacture
CA2348016A1 (en) Controlled release liquid delivery compositions with low initial drug burst
GEP20053427B (en) Pharmaceutical Compositions Providing Enhanced Drug Concentrations
GR3030732T3 (en) Pharmaceutical compositions including a drug, a cross-linked polymeric substance, an oil, and a surface active agent.
HUT53813A (en) Coating material controlling release of medicaments
IL115138A0 (en) Implantable polymer-containing molded articles for the administration of active substances to plants and processes for the preparation thereof
HK1027751A1 (en) Pharmaceutical compositions containing vitamin D and calcium, their preparation and therapeutic use.
GEP20033012B (en) Liquid Polymeric Compositions for Controlled Release of Bioactive Substances
ATE85213T1 (en) A MEDICINAL PRODUCT CONTAINING AN ACTIVE SUBSTANCE AND A WATER-SWELLING POLYMER.
GR1000266B (en) Preparation method of a composition based on a polyester for the controlled emission of pharmaceutical substances