ES2007377A6 - Un procedimiento para la preparacion de una composicion farmaceutica - Google Patents

Un procedimiento para la preparacion de una composicion farmaceutica

Info

Publication number
ES2007377A6
ES2007377A6 ES8702231A ES8702231A ES2007377A6 ES 2007377 A6 ES2007377 A6 ES 2007377A6 ES 8702231 A ES8702231 A ES 8702231A ES 8702231 A ES8702231 A ES 8702231A ES 2007377 A6 ES2007377 A6 ES 2007377A6
Authority
ES
Spain
Prior art keywords
preparation
procedure
pharmaceutical composition
solution
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8702231A
Other languages
English (en)
Inventor
Kazumi Ogata
Hideo Terayama
Satoshi Takei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Publication of ES2007377A6 publication Critical patent/ES2007377A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE UNA COMPOSICION FARMACEUTICA CONSTITUIDA POR UNA SOLUCION ISOTONICA ESTABLE DEL ACIDO 1-ETIL-6,8-DIFLUOR-1,4-DIHIDRO-7-(3-METIL-1-PIPERAZINIL)-4-OXOQUINOLIN-3- CARBOXILICO (I) O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO QUE CONSISTE EN AÑADIR AL COMPUESTO DE FORMULA (I) AGUA Y UN AGENTE ISOTONIZANTE SELECCIONADO ENTRE UN POLIALCOHOL O ACIDO BORICO Y AJUSTAR EL PH DE LA SOLUCION A UN VALOR COMPRENDIDO ENTRE 3 Y 6,5 APROXIMADAMENTE.EL COMPUESTO (I) ES UN MICROBICIDA DE AMPLIO ESPECTRO ANTIBACTERIANO CONTRA MICROOGANISMOS GRAM-POSITIVOS Y GRAM-NEGATIVOS Y LAS SOLUCIONES ISOTONICAS OBTENIDAS SON MUY ADECUADAS PARA LA PREPARACION DE COMPOSICIONES FARMACEUTICAS EN FORMA DE SOLUCIONES INYECTABLES, GOTAS OTICAS, SOLUCION INTRANASAL O SOLUCION OFTALMICA.
ES8702231A 1987-01-14 1987-07-29 Un procedimiento para la preparacion de una composicion farmaceutica Expired ES2007377A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62006727A JPH0696533B2 (ja) 1987-01-14 1987-01-14 キノロンカルボン酸の水性組成物

Publications (1)

Publication Number Publication Date
ES2007377A6 true ES2007377A6 (es) 1989-06-16

Family

ID=11646274

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8702231A Expired ES2007377A6 (es) 1987-01-14 1987-07-29 Un procedimiento para la preparacion de una composicion farmaceutica

Country Status (11)

Country Link
US (1) US4780465A (es)
JP (1) JPH0696533B2 (es)
CA (1) CA1284109C (es)
CH (1) CH676549A5 (es)
DE (1) DE3715918A1 (es)
ES (1) ES2007377A6 (es)
FR (1) FR2609394B1 (es)
GB (1) GB2199745B (es)
IT (1) IT1205113B (es)
PT (1) PT85808B (es)
SE (1) SE503256C2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2549285B2 (ja) * 1987-02-02 1996-10-30 第一製薬株式会社 鼻用噴霧剤
DE69004066T2 (de) * 1989-08-03 1994-02-17 Eisai Co Ltd Verfahren zur photostabilisierung von augenspüllösungen.
US5290774A (en) * 1989-08-03 1994-03-01 Eisai Co., Ltd. Photostabilizing method for ophthalmic solutions and the resulting ophthalmic solutions therefrom
FR2679773A1 (fr) * 1991-07-30 1993-02-05 Merck Sharp & Dohme Preparation ophtalmique contenant un agent osmotique acceptable antimicrobien.
US5505953A (en) 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
CN1133432C (zh) 1998-08-21 2004-01-07 千寿制药株式会社 含水液体药物组合物
KR100473963B1 (ko) * 1998-12-14 2005-08-02 씨제이 주식회사 퀴놀론계항균화합물의주사또는주입용수용액제제
US7625574B2 (en) * 2001-09-28 2009-12-01 Shiseido Research Center Skin treatment composition
JP4881159B2 (ja) * 2004-03-18 2012-02-22 株式会社アールテック・ウエノ チアゾール誘導体を含む水性組成物
ITTO20050533A1 (it) * 2005-07-29 2007-01-30 Euro Pharma S R L Soluzioni otologiche a base di estratti di lapacho
BRPI0719514A2 (pt) * 2006-10-12 2014-10-07 Kyorin Seiyaku Kk Preparações líquidas aquosas compreendendo gatifloxacina
TW200900066A (en) * 2007-03-22 2009-01-01 Daiichi Sankyo Co Ltd Quinolone medical composition containing alcohols

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017622A (en) * 1972-12-18 1977-04-12 Dainippon Pharmaceutical Co., Ltd. Piperazine derivatives
US4292317A (en) * 1977-09-20 1981-09-29 Laboratorie Roger Bellon 1,4-Dihydro-quinoline-3-carboxylic acid derivatives, process for their preparation and compositions containing them
DE3333719A1 (de) * 1983-09-17 1985-04-04 Bayer Ag Loesungen milchsaurer salze von piperazinylchinolon- und piperazinyl-azachinoloncarbonsaeuren
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
US4551456A (en) * 1983-11-14 1985-11-05 Merck & Co., Inc. Ophthalmic use of norfloxacin and related antibiotics
IT1196051B (it) * 1984-03-16 1988-11-10 Schiena Ricerche Composti ad attivita' antibatterica
JPS60246313A (ja) * 1984-05-22 1985-12-06 Yamanouchi Pharmaceut Co Ltd 塩酸ニカルジピンの注射剤およびその製法
JPS61180771A (ja) * 1985-01-05 1986-08-13 バイエル・アクチエンゲゼルシヤフト 安定な抗バクテリア剤水溶液
DE3517709A1 (de) * 1985-01-05 1986-07-10 Bayer Ag Basische zubereitungen von chinoloncarbonsaeuren
HUT40429A (en) * 1985-04-29 1986-12-28 Chinoin Gyogyszer Es Vegyeszet Process for production of salts of derivatives of kynolin carbonic acid

Also Published As

Publication number Publication date
IT1205113B (it) 1989-03-15
DE3715918A1 (de) 1988-07-28
DE3715918C2 (es) 1992-04-02
GB8711275D0 (en) 1987-06-17
PT85808A (en) 1987-10-01
FR2609394B1 (fr) 1991-06-21
IT8720727A0 (it) 1987-05-29
SE8701961L (sv) 1988-07-15
JPS63174930A (ja) 1988-07-19
PT85808B (pt) 1990-11-20
US4780465A (en) 1988-10-25
FR2609394A1 (fr) 1988-07-15
GB2199745B (en) 1990-09-26
SE503256C2 (sv) 1996-04-29
JPH0696533B2 (ja) 1994-11-30
GB2199745A (en) 1988-07-20
CA1284109C (en) 1991-05-14
SE8701961D0 (sv) 1987-05-13
CH676549A5 (es) 1991-02-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20070730