ES2006539A6 - Procedimiento de preparar nuevas aminoalcanoil-dibenzo(d,g)(1,3,6)dioxazocinas. - Google Patents

Procedimiento de preparar nuevas aminoalcanoil-dibenzo(d,g)(1,3,6)dioxazocinas.

Info

Publication number
ES2006539A6
ES2006539A6 ES8800216A ES8800216A ES2006539A6 ES 2006539 A6 ES2006539 A6 ES 2006539A6 ES 8800216 A ES8800216 A ES 8800216A ES 8800216 A ES8800216 A ES 8800216A ES 2006539 A6 ES2006539 A6 ES 2006539A6
Authority
ES
Spain
Prior art keywords
dioxazocines
aminoalkanoyl
dibenzo
preparation
nitrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8800216A
Other languages
English (en)
Inventor
Laszlo Rozsa
Lujza Petocz
Marton Fekete
Eniko Szirt Nee Kiszelly
Maria Hegedus
Istvan Gacsalyi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES2006539A6 publication Critical patent/ES2006539A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C07D273/01—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO DE PREPARAR NUEVAS AMINOALCANOIL-DIBENZO(D,G)(1,3,6)DIOXAZOCINAS, DE LA FORMULA (I) DADA EN LA DESCRIPCION, SEGUN LA CUAL UNA DIBENZO(D,G)(1,3,6)DIOXAZOCINA SE ACILA CON UN COMPUESTO DE LA FORMULA HAL-C=O-A-HAL'' Y LA ALCANOIL-DIBENZO(D,G)(1,3,6)DIOXAZOCINA ASI OBTENIDA SE HACE REACCIONAR CON UNA AMINA; EN LA DESCRIPCION Y LAS REIVINDICACIONES SE PRESENTAN ALTERNATIVAS QUE ACABAN OPCIONALMENTE CON LA CONVERSION DEL PRODUCTO EN UNA SAL DE ADICION DE ACIDO O CON LA LIBERACION DEL COMPUESTO DE FORMULA (I) DE UNA SAL DE ADICION DE ACIDO, MEDIANTE EL EMPLEO DE UNA BASE. LOS COMPUESTOS OBTENIDOS SON PARTICULARMENTE APLICABLES COMO ANESTESICOS, TRANQUILO-SEDANTES Y ANTIPARKINSONICOS.
ES8800216A 1986-12-30 1987-12-29 Procedimiento de preparar nuevas aminoalcanoil-dibenzo(d,g)(1,3,6)dioxazocinas. Expired ES2006539A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU865513A HU198194B (en) 1986-12-30 1986-12-30 Process for production of new derivatives of dioxazocin and medical compositions containing them

Publications (1)

Publication Number Publication Date
ES2006539A6 true ES2006539A6 (es) 1989-05-01

Family

ID=10970381

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8800216A Expired ES2006539A6 (es) 1986-12-30 1987-12-29 Procedimiento de preparar nuevas aminoalcanoil-dibenzo(d,g)(1,3,6)dioxazocinas.

Country Status (26)

Country Link
JP (1) JPS63174978A (es)
KR (1) KR880007502A (es)
CN (1) CN87108190A (es)
AT (1) AT389304B (es)
AU (1) AU596258B2 (es)
BE (1) BE1001240A3 (es)
CH (1) CH675877A5 (es)
CS (1) CS270579B2 (es)
DD (1) DD267038A5 (es)
DE (1) DE3744549A1 (es)
DK (1) DK691087A (es)
ES (1) ES2006539A6 (es)
FI (1) FI875767A (es)
FR (1) FR2609030B1 (es)
GB (1) GB2199827B (es)
GR (1) GR872083B (es)
HU (1) HU198194B (es)
IL (1) IL84976A (es)
IT (1) IT1233443B (es)
NL (1) NL8703150A (es)
NO (1) NO169230B (es)
PL (1) PL151402B1 (es)
SE (1) SE465429B (es)
SU (1) SU1575938A3 (es)
YU (1) YU235287A (es)
ZA (1) ZA879733B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201318B (en) * 1987-12-31 1990-10-28 Egyt Gyogyszervegyeszeti Gyar Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same
ATE91487T1 (de) * 1989-10-20 1993-07-15 Akzo Nv Dibenzodioxazecin- und dibenzodioxaazacycloundecin-derivate.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2659M (fr) * 1963-04-25 1964-08-14 Millot Lab Médicament a base de dérivé de la phénothiazine.
HU174126B (hu) * 1977-08-02 1979-11-28 Egyt Gyogyszervegyeszeti Gyar Sposob poluchenija novykh proizvodnykh dibenzo-kvadratnaja skobka-d,g-kvadratnaja skobka zakryta-kvadratnaja skobka-1,3,6-kvadratnaja skobka zakryta-dioksazocina
HU195491B (en) * 1985-12-20 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
HU201318B (en) * 1987-12-31 1990-10-28 Egyt Gyogyszervegyeszeti Gyar Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same

Also Published As

Publication number Publication date
SE8705187L (sv) 1988-07-01
BE1001240A3 (fr) 1989-08-29
CS270579B2 (en) 1990-07-12
DK691087A (da) 1988-07-01
FR2609030B1 (fr) 1991-05-31
FI875767A0 (fi) 1987-12-30
CS1009187A2 (en) 1989-11-14
CN87108190A (zh) 1988-07-13
AU8314087A (en) 1988-06-30
KR880007502A (ko) 1988-08-27
DD267038A5 (de) 1989-04-19
SE465429B (sv) 1991-09-09
HUT47260A (en) 1989-02-28
IT8723271A0 (it) 1987-12-30
NO875465L (no) 1988-07-01
IT1233443B (it) 1992-04-01
GB8730298D0 (en) 1988-02-03
PL269812A1 (en) 1988-09-15
IL84976A (en) 1991-09-16
CH675877A5 (es) 1990-11-15
AU596258B2 (en) 1990-04-26
NL8703150A (nl) 1988-07-18
IL84976A0 (en) 1988-06-30
PL151402B1 (en) 1990-08-31
SE8705187D0 (sv) 1987-12-29
ATA345087A (de) 1989-04-15
AT389304B (de) 1989-11-27
NO875465D0 (no) 1987-12-29
GB2199827A (en) 1988-07-20
GR872083B (en) 1988-04-27
HU198194B (en) 1989-08-28
FR2609030A1 (fr) 1988-07-01
NO169230B (no) 1992-02-17
JPS63174978A (ja) 1988-07-19
ZA879733B (en) 1988-06-24
DK691087D0 (da) 1987-12-29
FI875767A (fi) 1988-07-01
DE3744549A1 (de) 1988-07-14
YU235287A (en) 1988-10-31
GB2199827B (en) 1990-10-03
SU1575938A3 (ru) 1990-06-30

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2007-12-29

FD1A Patent lapsed

Effective date: 20010301