ES8104285A1 - Un procedimiento para la obtencion de un derivado del acido clarulanico. - Google Patents

Un procedimiento para la obtencion de un derivado del acido clarulanico.

Info

Publication number
ES8104285A1
ES8104285A1 ES490721A ES490721A ES8104285A1 ES 8104285 A1 ES8104285 A1 ES 8104285A1 ES 490721 A ES490721 A ES 490721A ES 490721 A ES490721 A ES 490721A ES 8104285 A1 ES8104285 A1 ES 8104285A1
Authority
ES
Spain
Prior art keywords
preparation
pharmaceutical compositions
acid derivatives
clavulanic acid
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490721A
Other languages
English (en)
Other versions
ES490721A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8104285A1 publication Critical patent/ES8104285A1/es
Publication of ES490721A0 publication Critical patent/ES490721A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO DEL ACIDO CLAVULANICO, DE FORMULA (I), O UNA SAL, O UN ESTER ESCINDIBLE DEL MISMO, DONDE X ES UN ATOMO DE AZUFRE O UN GRUPO SO O SO2. CONSISTE EN HACER REACCIONAR UN ESTER ESCINDIBLE DE UN COMPUESTO DE FORMULA (II), CON UN COMPUESTO DE FORMULA (III), SIENDO Y UN ATOMO O GRUPO DESPLAZABLE; W PUEDE SER DISTINTOS TIPOS DE RADICALES. LA REACCION SE REALIZA EN PRESENCIA DE UNA FOSFINA. ESTE COMPUESTO PRESENTA PROPIEDADES ANTIBACTERIANAS. *FORMULA*
ES490721A 1979-04-21 1980-04-18 Un procedimiento para la obtencion de un derivado del acido clarulanico. Granted ES490721A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7913949 1979-04-21

Publications (2)

Publication Number Publication Date
ES8104285A1 true ES8104285A1 (es) 1981-04-16
ES490721A0 ES490721A0 (es) 1981-04-16

Family

ID=10504697

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490721A Granted ES490721A0 (es) 1979-04-21 1980-04-18 Un procedimiento para la obtencion de un derivado del acido clarulanico.

Country Status (7)

Country Link
EP (1) EP0018203B1 (es)
JP (1) JPS55143991A (es)
AU (1) AU5758980A (es)
DE (1) DE3062168D1 (es)
DK (1) DK167780A (es)
ES (1) ES490721A0 (es)
ZA (1) ZA802323B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6472383B1 (en) 1994-04-25 2002-10-29 Smithkline Beecham P.L.C. Pharmaceutical formulations
EP0758240B1 (en) * 1994-04-25 2003-10-29 SmithKline Beecham plc Pharmaceutical formulations containing a beta-lactamase inhibiting penem in combination with a beta-lactam antibiotic and their use in the treatment of bacterial infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL50080A (en) * 1975-07-29 1979-07-25 Beecham Group Ltd 4-oxa-1-azabicyclo(3.2.0)heptan-7-one-2-car boxylic acid derivatives and their preparation
GB1574906A (en) * 1976-01-31 1980-09-10 Beecham Group Ltd Therapeutic compounds containing - lactams
IL51267A (en) * 1976-01-31 1979-12-30 Beecham Group Ltd Clavulanic acid thioethers their preparation and pharmaceutical compositions containing them
BE851821A (fr) * 1976-02-27 1977-08-25 Glaxo Lab Ltd Antibiotiques, inhibiteurs de 3-lactamases, clavulamiques et leur preparation

Also Published As

Publication number Publication date
EP0018203A1 (en) 1980-10-29
EP0018203B1 (en) 1983-03-02
DE3062168D1 (en) 1983-04-07
ZA802323B (en) 1981-04-29
JPS55143991A (en) 1980-11-10
AU5758980A (en) 1980-10-30
DK167780A (da) 1980-10-22
ES490721A0 (es) 1981-04-16

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