HU198194B - Process for production of new derivatives of dioxazocin and medical compositions containing them - Google Patents

Process for production of new derivatives of dioxazocin and medical compositions containing them Download PDF

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Publication number
HU198194B
HU198194B HU865513A HU551386A HU198194B HU 198194 B HU198194 B HU 198194B HU 865513 A HU865513 A HU 865513A HU 551386 A HU551386 A HU 551386A HU 198194 B HU198194 B HU 198194B
Authority
HU
Hungary
Prior art keywords
formula
mol
chloro
dioxazocine
compound
Prior art date
Application number
HU865513A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT47260A (en
Inventor
Laszlo Rozsa
Lujza Petoecz
Marton Fekete
Kiszelly Enokoe Szirtne
Maria Hegedues
Istvan Gacsanyi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU865513A priority Critical patent/HU198194B/hu
Priority to YU02352/87A priority patent/YU235287A/xx
Priority to CN198787108190A priority patent/CN87108190A/zh
Priority to ZA879733A priority patent/ZA879733B/xx
Priority to SE8705187A priority patent/SE465429B/sv
Priority to DK691087A priority patent/DK691087A/da
Priority to PH36312A priority patent/PH24384A/en
Priority to NO875465A priority patent/NO169230B/no
Priority to ES8800216A priority patent/ES2006539A6/es
Priority to CS8710091A priority patent/CS270579B2/cs
Priority to DD87311670A priority patent/DD267038A5/de
Priority to CH5095/87A priority patent/CH675877A5/de
Priority to IL84976A priority patent/IL84976A/xx
Priority to FR878718272A priority patent/FR2609030B1/fr
Priority to BE8701495A priority patent/BE1001240A3/fr
Priority to NL8703150A priority patent/NL8703150A/nl
Priority to AT0345087A priority patent/AT389304B/de
Priority to SU874203954A priority patent/SU1575938A3/ru
Priority to AU83140/87A priority patent/AU596258B2/en
Priority to IT8723271A priority patent/IT1233443B/it
Priority to PL1987269812A priority patent/PL151402B1/pl
Priority to FI875767A priority patent/FI875767A/fi
Priority to DE19873744549 priority patent/DE3744549A1/de
Priority to KR1019870015470A priority patent/KR880007502A/ko
Priority to GB8730298A priority patent/GB2199827B/en
Priority to GR872083A priority patent/GR872083B/el
Priority to JP63000045A priority patent/JPS63174978A/ja
Publication of HUT47260A publication Critical patent/HUT47260A/hu
Publication of HU198194B publication Critical patent/HU198194B/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C07D273/01Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having one nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU865513A 1986-12-30 1986-12-30 Process for production of new derivatives of dioxazocin and medical compositions containing them HU198194B (en)

Priority Applications (27)

Application Number Priority Date Filing Date Title
HU865513A HU198194B (en) 1986-12-30 1986-12-30 Process for production of new derivatives of dioxazocin and medical compositions containing them
YU02352/87A YU235287A (en) 1986-12-30 1987-12-22 Process for obtaining new amino-alcanoil-dibenzo-/d,g//1,3,6/-dioxazocine
CN198787108190A CN87108190A (zh) 1986-12-30 1987-12-28 新型氨基烷酰基-二苯并[d,g][1,3,6]二氧杂氮杂辛因及其制备方法
ZA879733A ZA879733B (en) 1986-12-30 1987-12-29 Novel aminoalkanoyl-dibenzo(d,g)(1,3,6)dioxazocines and a process for the preparation thereof
SE8705187A SE465429B (sv) 1986-12-30 1987-12-29 Nya aminoalkanoyl-dibenso /d,g/ /1,3,6/ dioxazociner, foerfarande foer framstaellning daerav samt farmaceutisk beredning
DK691087A DK691087A (da) 1986-12-30 1987-12-29 Dioxazocinderivater
PH36312A PH24384A (en) 1986-12-30 1987-12-29 Aminoalkanoyl-dibenzo (d,g) (1,3,6) dioxazocines and composition thereof
NO875465A NO169230B (no) 1986-12-30 1987-12-29 Analogifremgangsmaate for fremstilling av terapeutisk aktive aminoalkanoyl-dibenzo(d,g)(1,3,6)dioxazociner
ES8800216A ES2006539A6 (es) 1986-12-30 1987-12-29 Procedimiento de preparar nuevas aminoalcanoil-dibenzo(d,g)(1,3,6)dioxazocinas.
CS8710091A CS270579B2 (en) 1986-12-30 1987-12-29 Method of new aminoalkanoyl-dibenzo (d,g) (1,3,6) dioxazocines production
DD87311670A DD267038A5 (de) 1986-12-30 1987-12-29 Verfahren zur herstellung von neuen aminoalkanoyl-dibenzo [d,g][1,3,6]dioxazocinderivaten
CH5095/87A CH675877A5 (es) 1986-12-30 1987-12-29
IL84976A IL84976A (en) 1986-12-30 1987-12-29 Aminoalkanoyl-dibenzo-(d,g)(1,3,6)dioxazocines,their preparation and pharmaceutical compositions containing them
FR878718272A FR2609030B1 (fr) 1986-12-30 1987-12-29 Nouvelles aminoalcanoyldibenzo (d, q) (1,3,6) dioxazocines, leur procede de preparation et compositions pharmaceutiques les contenant
BE8701495A BE1001240A3 (fr) 1986-12-30 1987-12-29 Nouvelles aminoalcanoyldibenzo [d,g][1,3,6] dioxazocines et leur procede de preparation.
NL8703150A NL8703150A (nl) 1986-12-30 1987-12-29 Nieuwe aminoalkanoyl-dibenzo d,g 1,3,6 dioxazocinen en een werkwijze voor de bereiding ervan.
AT0345087A AT389304B (de) 1986-12-30 1987-12-30 Neue aminoalkanoyl-dibenzo (d,g) (1,3,6)dioxazocinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
SU874203954A SU1575938A3 (ru) 1986-12-30 1987-12-30 Способ получени производных аминоалканоилдибензо ( @ , @ ) (1,3,6) диоксазоцина или их фармацевтически приемлемых аддитивных солей с кислотами
AU83140/87A AU596258B2 (en) 1986-12-30 1987-12-30 Novel aminoalkanoyl-dibenzo(d,g)(1,3,6)dioxazocines and a process for the preparation thereof
IT8723271A IT1233443B (it) 1986-12-30 1987-12-30 Amminoalcanoil-dibenzo (d,g,) (1,3,6) diossazocine e procedimento per la loro preparazione
PL1987269812A PL151402B1 (en) 1986-12-30 1987-12-30 Novel aminoalkanoyl-dibenzo(d g)(1 3 6)dioxazocines & process for preparation thereof
FI875767A FI875767A (fi) 1986-12-30 1987-12-30 Foerfarande foer framstaellning av nya aminoalkanoyl-dibenso (d,g) (1,3,6) dioxaziner.
DE19873744549 DE3744549A1 (de) 1986-12-30 1987-12-30 12h-12-(carbamoyl)- beziehungsweise 12h-12-aminoalkanoyl)-dibenzo(d,g)(1,3,6)dioxazocinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
KR1019870015470A KR880007502A (ko) 1986-12-30 1987-12-30 신규의 아미노알카노일-디벤조[d, g][1,3,6]디옥사조신 및 그의 제조방법
GB8730298A GB2199827B (en) 1986-12-30 1987-12-30 Novel aminoalkanoyl-dibenzo[d,g][1,3,6]dioxazocines and a process for the preparation thereof
GR872083A GR872083B (en) 1986-12-30 1987-12-30 Preparation process of aminoalkanoyl-dibenzo (d,g),(1,3,6) dioxazocines
JP63000045A JPS63174978A (ja) 1986-12-30 1988-01-04 新規なアミノアルカイノイルージベンゾ−d,g−1,3,6−ジオキサゾシン及びその製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU865513A HU198194B (en) 1986-12-30 1986-12-30 Process for production of new derivatives of dioxazocin and medical compositions containing them

Publications (2)

Publication Number Publication Date
HUT47260A HUT47260A (en) 1989-02-28
HU198194B true HU198194B (en) 1989-08-28

Family

ID=10970381

Family Applications (1)

Application Number Title Priority Date Filing Date
HU865513A HU198194B (en) 1986-12-30 1986-12-30 Process for production of new derivatives of dioxazocin and medical compositions containing them

Country Status (26)

Country Link
JP (1) JPS63174978A (es)
KR (1) KR880007502A (es)
CN (1) CN87108190A (es)
AT (1) AT389304B (es)
AU (1) AU596258B2 (es)
BE (1) BE1001240A3 (es)
CH (1) CH675877A5 (es)
CS (1) CS270579B2 (es)
DD (1) DD267038A5 (es)
DE (1) DE3744549A1 (es)
DK (1) DK691087A (es)
ES (1) ES2006539A6 (es)
FI (1) FI875767A (es)
FR (1) FR2609030B1 (es)
GB (1) GB2199827B (es)
GR (1) GR872083B (es)
HU (1) HU198194B (es)
IL (1) IL84976A (es)
IT (1) IT1233443B (es)
NL (1) NL8703150A (es)
NO (1) NO169230B (es)
PL (1) PL151402B1 (es)
SE (1) SE465429B (es)
SU (1) SU1575938A3 (es)
YU (1) YU235287A (es)
ZA (1) ZA879733B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201318B (en) * 1987-12-31 1990-10-28 Egyt Gyogyszervegyeszeti Gyar Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same
ATE91487T1 (de) * 1989-10-20 1993-07-15 Akzo Nv Dibenzodioxazecin- und dibenzodioxaazacycloundecin-derivate.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2659M (fr) * 1963-04-25 1964-08-14 Millot Lab Médicament a base de dérivé de la phénothiazine.
HU174126B (hu) * 1977-08-02 1979-11-28 Egyt Gyogyszervegyeszeti Gyar Sposob poluchenija novykh proizvodnykh dibenzo-kvadratnaja skobka-d,g-kvadratnaja skobka zakryta-kvadratnaja skobka-1,3,6-kvadratnaja skobka zakryta-dioksazocina
HU195491B (en) * 1985-12-20 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
HU201318B (en) * 1987-12-31 1990-10-28 Egyt Gyogyszervegyeszeti Gyar Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same

Also Published As

Publication number Publication date
NO875465D0 (no) 1987-12-29
SE465429B (sv) 1991-09-09
SE8705187L (sv) 1988-07-01
AU596258B2 (en) 1990-04-26
CN87108190A (zh) 1988-07-13
DE3744549A1 (de) 1988-07-14
KR880007502A (ko) 1988-08-27
HUT47260A (en) 1989-02-28
NL8703150A (nl) 1988-07-18
FI875767A0 (fi) 1987-12-30
DK691087D0 (da) 1987-12-29
CH675877A5 (es) 1990-11-15
IL84976A0 (en) 1988-06-30
PL151402B1 (en) 1990-08-31
ATA345087A (de) 1989-04-15
AT389304B (de) 1989-11-27
ZA879733B (en) 1988-06-24
FR2609030A1 (fr) 1988-07-01
IT1233443B (it) 1992-04-01
PL269812A1 (en) 1988-09-15
GB2199827A (en) 1988-07-20
JPS63174978A (ja) 1988-07-19
IL84976A (en) 1991-09-16
YU235287A (en) 1988-10-31
CS1009187A2 (en) 1989-11-14
FI875767A (fi) 1988-07-01
NO875465L (no) 1988-07-01
DK691087A (da) 1988-07-01
GB8730298D0 (en) 1988-02-03
FR2609030B1 (fr) 1991-05-31
ES2006539A6 (es) 1989-05-01
IT8723271A0 (it) 1987-12-30
SU1575938A3 (ru) 1990-06-30
GB2199827B (en) 1990-10-03
SE8705187D0 (sv) 1987-12-29
AU8314087A (en) 1988-06-30
GR872083B (en) 1988-04-27
CS270579B2 (en) 1990-07-12
BE1001240A3 (fr) 1989-08-29
NO169230B (no) 1992-02-17
DD267038A5 (de) 1989-04-19

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee