ES482540A1 - Procedimiento para la preparacion de 2-fenilamino-imidazoli-na-(2) sustituidas. - Google Patents

Procedimiento para la preparacion de 2-fenilamino-imidazoli-na-(2) sustituidas.

Info

Publication number
ES482540A1
ES482540A1 ES482540A ES482540A ES482540A1 ES 482540 A1 ES482540 A1 ES 482540A1 ES 482540 A ES482540 A ES 482540A ES 482540 A ES482540 A ES 482540A ES 482540 A1 ES482540 A1 ES 482540A1
Authority
ES
Spain
Prior art keywords
substituted
acid addition
addition salts
imidazolines
phenylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES482540A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES482540A1 publication Critical patent/ES482540A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedimiento para la preparación de 2-fe- nilamino-imidazolinas-(2) sustituidas de la fórmula general **(Fórmula-01)** donde Ar significa 2,6-dibromofenilo, ó 3-bromo-4- fluorofenilo, y X significa oxígeno o azufre así como sus sales por adición de ácidos, caracterizado porque se hace reaccionar una 2- fenilamino-imidazolidina de la fórmula general **(Fórmula-02)** en donde Ar posee los significados mencionados anteriormente, con un halogenuro de la fórmula general **(Fórmula-03)** en donde Hal significa un átomo de cloro, bromo o yodo y X tiene el significado mencionado anteriormente, y porque eventualmente se transforma el producto final, obtenido según el modo de procedimiento, en una sal por adición de ácidos.
ES482540A 1978-07-18 1979-07-17 Procedimiento para la preparacion de 2-fenilamino-imidazoli-na-(2) sustituidas. Expired ES482540A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782831480 DE2831480A1 (de) 1978-07-18 1978-07-18 Neue substituierte 2-phenylamino- imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben

Publications (1)

Publication Number Publication Date
ES482540A1 true ES482540A1 (es) 1980-04-01

Family

ID=6044662

Family Applications (1)

Application Number Title Priority Date Filing Date
ES482540A Expired ES482540A1 (es) 1978-07-18 1979-07-17 Procedimiento para la preparacion de 2-fenilamino-imidazoli-na-(2) sustituidas.

Country Status (13)

Country Link
EP (1) EP0007428A1 (es)
JP (1) JPS5519264A (es)
AU (1) AU4899379A (es)
DE (1) DE2831480A1 (es)
DK (1) DK299779A (es)
ES (1) ES482540A1 (es)
FI (1) FI792234A (es)
GR (1) GR70254B (es)
IL (1) IL57820A0 (es)
NO (1) NO792368L (es)
NZ (1) NZ191037A (es)
PT (1) PT69926A (es)
ZA (1) ZA793604B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2951601A1 (de) * 1979-12-21 1981-07-02 C.H. Boehringer Sohn, 6507 Ingelheim Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2102733A1 (en) * 1971-01-21 1972-08-03 CH. Boehringer Sohn, 6507 Ingelheim 2-arylamino-2-imidazolines
US3850926A (en) * 1971-01-21 1974-11-26 Boehringer Sohn Ingelheim 2-(n-substituted-phenylamino)-imidazolines-(2)
DE2308883C3 (de) * 1973-02-23 1978-05-24 C.H. Boehringer Sohn, 6507 Ingelheim 2-Phenylamino-thienylmethyl-imidazoline-(2), Verfahren zur Herstellung derselben und diese enthaltene Arzneimittel

Also Published As

Publication number Publication date
IL57820A0 (en) 1979-11-30
ZA793604B (en) 1981-03-25
PT69926A (de) 1979-08-01
GR70254B (es) 1982-09-02
NZ191037A (en) 1981-04-24
AU4899379A (en) 1980-01-24
DE2831480A1 (de) 1980-01-31
NO792368L (no) 1980-01-21
FI792234A (fi) 1980-01-19
EP0007428A1 (de) 1980-02-06
DK299779A (da) 1980-01-19
JPS5519264A (en) 1980-02-09

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