ES8609286A1 - Un metodo para preparar un compuesto de morfolinol - Google Patents
Un metodo para preparar un compuesto de morfolinolInfo
- Publication number
- ES8609286A1 ES8609286A1 ES544862A ES544862A ES8609286A1 ES 8609286 A1 ES8609286 A1 ES 8609286A1 ES 544862 A ES544862 A ES 544862A ES 544862 A ES544862 A ES 544862A ES 8609286 A1 ES8609286 A1 ES 8609286A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- compounds
- pharmaceutical compounds
- hydrogen
- heterocyclic pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
METODO PARA PREPARAR NUEVOS MORFOLINOLES. CONSISTE EN HACER REACCIONAR UN C.D.F. (II) CON UN C.D.F. (III), EN ETANOL O METANOL, PARA OBTENER UN C.D.F. (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES DE ADICION DE ACIDOS. SIENDO: R, H O ALQUILO DE C 1 A 4; Y, H O FLUOR; L, BROMO O P-TOLUENSULFONILOXI. SE UTILIZAN EN FORMA DE CAPSULAS, SELLOS, TABLETAS O PASTILLAS PARA TRATAR LA PROFILAXIS EN MAMIFEROS Y LA DISCENISIS TARDIA (TARDIRE DYSKINESIA TD) Y LA DISFUNCION CEREBRAL MINIMA (MINIMAL BRAIN DYSFONCTION) EN SERES HUMANOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848417170A GB8417170D0 (en) | 1984-07-05 | 1984-07-05 | Heterocyclic pharmaceutical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
ES544862A0 ES544862A0 (es) | 1986-07-16 |
ES8609286A1 true ES8609286A1 (es) | 1986-07-16 |
Family
ID=10563453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES544862A Expired ES8609286A1 (es) | 1984-07-05 | 1985-07-04 | Un metodo para preparar un compuesto de morfolinol |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0170430A1 (es) |
JP (1) | JPS6124578A (es) |
KR (1) | KR860001083A (es) |
AU (1) | AU4459585A (es) |
DK (1) | DK307385A (es) |
ES (1) | ES8609286A1 (es) |
FI (1) | FI852657L (es) |
GB (1) | GB8417170D0 (es) |
GR (1) | GR851645B (es) |
HU (1) | HUT39437A (es) |
IL (1) | IL75720A0 (es) |
ZA (1) | ZA855072B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8924528D0 (en) * | 1989-10-31 | 1989-12-20 | Wellcome Found | Heterocyclic pharmaceutical compounds,preparation and use |
GB9108629D0 (en) * | 1991-04-23 | 1991-06-12 | Wellcome Found | Heterocyclic pharmaceutical compounds,preparation and use |
US7098206B2 (en) | 1998-01-21 | 2006-08-29 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
CA2318268A1 (en) | 1998-01-21 | 1999-07-29 | Glaxo Group Limited | Pharmaceutically active morpholinol |
US6998400B2 (en) | 1998-01-22 | 2006-02-14 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
US6734213B2 (en) | 1999-01-20 | 2004-05-11 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
US6855820B2 (en) | 1999-01-20 | 2005-02-15 | Smithkline Beecham Corporation | Pharmaceutically active morpholinol |
WO2007002597A2 (en) | 2005-06-27 | 2007-01-04 | Biovail Laboratories International S.R.L. | Modified-release formulations of a bupropion salt |
KR101014438B1 (ko) * | 2008-09-26 | 2011-02-14 | 동아제약주식회사 | 탁산 유도체의 제조방법 |
ES2546492T3 (es) * | 2010-05-21 | 2015-09-24 | Research Triangle Institute | Derivados de 1-fenilmorfolina como análogos de hidroxibupropion para tratar drogodependencia |
ES2687095T3 (es) | 2010-05-21 | 2018-10-23 | Research Triangle Institute | Fenilimorfolinas y análogos de las mismas |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3117967A (en) * | 1962-04-02 | 1964-01-14 | Smith Kline French Lab | 2-biphenylyl-2-hydroxy-morpholinium halides |
FR2553413B1 (fr) * | 1983-10-17 | 1986-03-21 | Lafon Labor | Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique |
-
1984
- 1984-07-05 GB GB848417170A patent/GB8417170D0/en active Pending
-
1985
- 1985-07-04 EP EP85304762A patent/EP0170430A1/en not_active Withdrawn
- 1985-07-04 HU HU852608A patent/HUT39437A/hu unknown
- 1985-07-04 IL IL75720A patent/IL75720A0/xx unknown
- 1985-07-04 KR KR1019850004786A patent/KR860001083A/ko not_active Application Discontinuation
- 1985-07-04 JP JP14762385A patent/JPS6124578A/ja active Pending
- 1985-07-04 ZA ZA855072A patent/ZA855072B/xx unknown
- 1985-07-04 AU AU44595/85A patent/AU4459585A/en not_active Abandoned
- 1985-07-04 DK DK307385A patent/DK307385A/da not_active Application Discontinuation
- 1985-07-04 ES ES544862A patent/ES8609286A1/es not_active Expired
- 1985-07-04 GR GR851645A patent/GR851645B/el unknown
- 1985-07-04 FI FI852657A patent/FI852657L/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES544862A0 (es) | 1986-07-16 |
GB8417170D0 (en) | 1984-08-08 |
DK307385D0 (da) | 1985-07-04 |
FI852657A0 (fi) | 1985-07-04 |
FI852657L (fi) | 1986-01-06 |
AU4459585A (en) | 1986-01-09 |
KR860001083A (ko) | 1986-02-22 |
HUT39437A (en) | 1986-09-29 |
ZA855072B (en) | 1987-02-25 |
JPS6124578A (ja) | 1986-02-03 |
GR851645B (es) | 1985-11-26 |
EP0170430A1 (en) | 1986-02-05 |
DK307385A (da) | 1986-01-06 |
IL75720A0 (en) | 1985-11-29 |
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