ES2004807A6 - Procedimiento para la produccion de una composicion farmaceutica nasal de octreotide - Google Patents
Procedimiento para la produccion de una composicion farmaceutica nasal de octreotideInfo
- Publication number
- ES2004807A6 ES2004807A6 ES8702432A ES8702432A ES2004807A6 ES 2004807 A6 ES2004807 A6 ES 2004807A6 ES 8702432 A ES8702432 A ES 8702432A ES 8702432 A ES8702432 A ES 8702432A ES 2004807 A6 ES2004807 A6 ES 2004807A6
- Authority
- ES
- Spain
- Prior art keywords
- compsn
- nasal
- octreotide
- procedure
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DEQANNDTNATYII-OULOTJBUSA-N (4r,7s,10s,13r,16s,19r)-10-(4-aminobutyl)-19-[[(2r)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-n-[(2r,3r)-1,3-dihydroxybutan-2-yl]-7-[(1r)-1-hydroxyethyl]-13-(1h-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxa Chemical group C([C@@H](N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC=2C3=CC=CC=C3NC=2)NC(=O)[C@H](CC=2C=CC=CC=2)NC1=O)C(=O)N[C@H](CO)[C@H](O)C)C1=CC=CC=C1 DEQANNDTNATYII-OULOTJBUSA-N 0.000 title abstract 2
- 108010016076 Octreotide Proteins 0.000 title abstract 2
- 229960002700 octreotide Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hcl hcl Chemical compound Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
- -1 nasal applicator Substances 0.000 abstract 1
- 239000007922 nasal spray Substances 0.000 abstract 1
- 229940097496 nasal spray Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 239000008215 water for injection Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868620035A GB8620035D0 (en) | 1986-08-18 | 1986-08-18 | Organic compounds |
| GB868626821A GB8626821D0 (en) | 1986-11-10 | 1986-11-10 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2004807A6 true ES2004807A6 (es) | 1989-02-01 |
Family
ID=26291187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8702432A Expired ES2004807A6 (es) | 1986-08-18 | 1987-08-18 | Procedimiento para la produccion de una composicion farmaceutica nasal de octreotide |
Country Status (24)
| Country | Link |
|---|---|
| KR (1) | KR880002537A (cs) |
| AT (1) | AT396331B (cs) |
| AU (2) | AU612589B2 (cs) |
| BE (1) | BE1001748A4 (cs) |
| CA (1) | CA1322331C (cs) |
| CH (1) | CH672252A5 (cs) |
| CS (1) | CS411491A3 (cs) |
| DE (1) | DE3726517A1 (cs) |
| DK (1) | DK428287A (cs) |
| ES (1) | ES2004807A6 (cs) |
| FI (1) | FI93307C (cs) |
| FR (1) | FR2602680B1 (cs) |
| GR (1) | GR871289B (cs) |
| HK (1) | HK80493A (cs) |
| HU (1) | HU200940B (cs) |
| IE (1) | IE60761B1 (cs) |
| IL (1) | IL83572A (cs) |
| IT (1) | IT1222510B (cs) |
| LU (1) | LU86971A1 (cs) |
| NL (1) | NL8701874A (cs) |
| NO (1) | NO175519C (cs) |
| NZ (1) | NZ221473A (cs) |
| PT (1) | PT85545B (cs) |
| SE (1) | SE8703183L (cs) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003216084A1 (en) | 2002-01-22 | 2003-09-02 | New York University | Methods for therapeutic treatment of benign prostatic hypertrophy (bph) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6034925B2 (ja) * | 1979-07-31 | 1985-08-12 | 帝人株式会社 | 持続性鼻腔用製剤およびその製造法 |
| ATE2512T1 (de) * | 1979-11-27 | 1983-03-15 | Sandoz Ag | Polypeptide, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen, die diese polypeptide enthalten, und ihre verwendung. |
| US4451394A (en) * | 1982-10-25 | 1984-05-29 | American Home Products Corporation | Dodecapeptides preventing glucose and triglyceride assimilation |
| JPS59163313A (ja) * | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
| US4505897A (en) * | 1983-04-18 | 1985-03-19 | The Administrators Of The Tulane Educational Fund | Cyclic pentapeptides displaying somatostatin antagonism and method of treatment of mammals therewith |
| GB8514090D0 (en) * | 1985-06-04 | 1985-07-10 | Sandoz Ltd | Organic compounds |
| US4612302A (en) * | 1983-11-14 | 1986-09-16 | Brigham And Women's Hospital | Clinical use of somatostatin analogues |
| JPS60224616A (ja) * | 1984-04-24 | 1985-11-09 | Teijin Ltd | 経鼻投与用組成物 |
| US4725577A (en) * | 1985-04-25 | 1988-02-16 | Administrators Of The Tulane Educational Fund | Biologically active lysine containing octapeptides |
| JPH085913B2 (ja) * | 1985-09-12 | 1996-01-24 | ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド | 治療用ソマトスタチン同族体 |
-
1987
- 1987-08-08 DE DE19873726517 patent/DE3726517A1/de not_active Ceased
- 1987-08-10 HU HU873618A patent/HU200940B/hu not_active IP Right Cessation
- 1987-08-10 FR FR8711402A patent/FR2602680B1/fr not_active Expired - Fee Related
- 1987-08-10 NL NL8701874A patent/NL8701874A/nl not_active Application Discontinuation
- 1987-08-10 BE BE8700893A patent/BE1001748A4/fr not_active IP Right Cessation
- 1987-08-14 CH CH3134/87A patent/CH672252A5/de not_active IP Right Cessation
- 1987-08-14 LU LU86971A patent/LU86971A1/fr unknown
- 1987-08-17 SE SE8703183A patent/SE8703183L/ not_active Application Discontinuation
- 1987-08-17 AT AT0206087A patent/AT396331B/de not_active IP Right Cessation
- 1987-08-17 AU AU77120/87A patent/AU612589B2/en not_active Ceased
- 1987-08-17 KR KR1019870008981A patent/KR880002537A/ko not_active Ceased
- 1987-08-17 NZ NZ221473A patent/NZ221473A/xx unknown
- 1987-08-17 GR GR871289A patent/GR871289B/el unknown
- 1987-08-17 PT PT85545A patent/PT85545B/pt not_active IP Right Cessation
- 1987-08-17 FI FI873548A patent/FI93307C/fi not_active IP Right Cessation
- 1987-08-17 NO NO873452A patent/NO175519C/no unknown
- 1987-08-17 IE IE218787A patent/IE60761B1/en not_active IP Right Cessation
- 1987-08-17 CA CA000544704A patent/CA1322331C/en not_active Expired - Fee Related
- 1987-08-17 DK DK428287A patent/DK428287A/da unknown
- 1987-08-17 IL IL83572A patent/IL83572A/xx not_active IP Right Cessation
- 1987-08-18 IT IT21670/87A patent/IT1222510B/it active
- 1987-08-18 ES ES8702432A patent/ES2004807A6/es not_active Expired
-
1991
- 1991-10-09 AU AU85689/91A patent/AU637530B2/en not_active Ceased
- 1991-12-27 CS CS914114A patent/CS411491A3/cs unknown
-
1993
- 1993-08-05 HK HK804/93A patent/HK80493A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20001204 |