EP3750521B1 - Système de prise en charge de vérification de médicament - Google Patents

Système de prise en charge de vérification de médicament Download PDF

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Publication number
EP3750521B1
EP3750521B1 EP18905390.3A EP18905390A EP3750521B1 EP 3750521 B1 EP3750521 B1 EP 3750521B1 EP 18905390 A EP18905390 A EP 18905390A EP 3750521 B1 EP3750521 B1 EP 3750521B1
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EP
European Patent Office
Prior art keywords
machine
packaging
auditing
sachets
medication
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP18905390.3A
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German (de)
English (en)
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EP3750521A1 (fr
EP3750521A4 (fr
Inventor
Yu Tojo
Hirokazu Okutsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Toyama Chemical Co Ltd
Original Assignee
Fujifilm Toyama Chemical Co Ltd
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Filing date
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Application filed by Fujifilm Toyama Chemical Co Ltd filed Critical Fujifilm Toyama Chemical Co Ltd
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Publication of EP3750521A4 publication Critical patent/EP3750521A4/fr
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B57/00—Automatic control, checking, warning, or safety devices
    • B65B57/02—Automatic control, checking, warning, or safety devices responsive to absence, presence, abnormal feed, or misplacement of binding or wrapping material, containers, or packages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B43/00—Forming, feeding, opening or setting-up containers or receptacles in association with packaging
    • B65B43/12—Feeding flexible bags or carton blanks in flat or collapsed state; Feeding flat bags connected to form a series or chain
    • B65B43/123—Feeding flat bags connected to form a series or chain
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/101—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
    • B65B5/103—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
    • B65B61/26—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for marking or coding completed packages
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B9/00—Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
    • B65B9/06—Enclosing successive articles, or quantities of material, in a longitudinally-folded web, or in a web folded into a tube about the articles or quantities of material placed upon it
    • B65B9/08—Enclosing successive articles, or quantities of material, in a longitudinally-folded web, or in a web folded into a tube about the articles or quantities of material placed upon it in a web folded and sealed transversely to form pockets which are subsequently filled and then closed by sealing

Definitions

  • the present invention relates to a medication auditing support system provided with a dose-packaging machine and an auditing machine.
  • the dose-packaging machine automates packaging work to put medication into packaging sachets based on prescription data. Further, the auditing machine automates auditing work to check whether the medications are put in packaging sachets according to the prescription data or not.
  • PTL 1 discloses: a packaged medication dispensing part having a discharging unit; a post-process part having a conveying unit and a packaged medication inspecting part; and a controlling part.
  • the controlling part associates a conveyance speed of the conveying unit and a discharge speed of the discharging unit, and controls at least one of the conveying unit and the discharging unit so that a post-process is performed without a bundle of packaged medications being damaged.
  • PTL 2 describes a medicine wrapping machine solving the problem to merely set reels for an automatic post-process by installing a winding machine receiving a wrapped bag delivered from a wrapping machine and winding it on the reels.
  • PTL 3 - PTL 11 contribute technological background to the present invention.
  • the present invention has been made in consideration of such a situation, and aims to provide a medication auditing support system capable of adjusting a difference between processing speeds of a dose-packaging machine and an auditing machine.
  • the invention provides a medication auditing support system according to claim 1. Preferred embodiments of the invention are disclosed in the dependent claims.
  • a medication auditing support system of a first aspect is provided with: a dose-packaging machine configured to package medication based on prescription data and discharge continuous packaging sachets; a conveying machine configured to receive the continuous packaging sachets discharged from the dose-packaging machine and feed the continuous packaging sachets in a length direction; an auditing machine configured to feed the packaging sachets to the auditing machine and a route to feed the packaging sachets to a place other than the auditing machine.
  • a buffer unit is provided, it is possible to adjust a difference between processing speeds of a dose-packaging machine and an auditing machine.
  • Medication prescribing work performed in hospitals, pharmacies and the like includes prescription data inputting work, picking work, automatic packaging work, dispensing auditing work, and administration guiding and prescribing work, when being roughly classified.
  • administration guiding and prescribing work a pharmacist performs administration guidance to a patient, and prescribes packaged medication, after the dispensing auditing work.
  • the prescription data includes, for example, a patient's name and age, a medication type of a medication or a name of the medication, an amount of the medication, usage of the medication, or a dose of the medication and the like.
  • medication type of a medication in the present specification is synonymous with a classification of the medication or a kind of the medication.
  • the pharmacist operates the receipt computer to print the prescription data from a printer connected to the receipt computer.
  • the pharmacist picks a medication corresponding to the prescription data from a medication shelf.
  • the medication includes, for example, tablets, capsules and the like.
  • an automatic picking device configured to automatically pick the medication based on the prescription data inputted to the receipt computer may be used.
  • FIG 1 is a schematic configuration diagram of a medication auditing support system.
  • a medication auditing support system 10 is provided with: a dose-packaging machine 100; a conveying machine 200; an auditing machine 300; and a controlling machine 500 configured to control the dose-packaging machine 100, the conveying machine 200 and the auditing machine 300.
  • up/upward and “down/downward” indicating directions respectively mean “up/upward” and “down/downward” when the medication auditing support system is installed in a normal use state.
  • vertical (longitudinal) and “horizontal (lateral) with reference to a folded portion of a long (continuous) packaging paper, respectively mean a direction orthogonal to the folded portion and a direction parallel to the folded portion.
  • orthogonal includes “substantially orthogonal”
  • parallel includes “substantially parallel”.
  • upstream and downstream with regard to a conveyance direction of packaging paper or packaging sachets (packaging sachets), a conveyance destination direction side relative to a certain reference means “downstream”, and a side opposite to the conveyance destination direction means “upstream”.
  • controlling machine 500 for example, a personal computer is given. Prescription data is inputted to the controlling machine 500 from a receipt computer online.
  • the controlling machine 500 is provided, for example, with a displaying unit 502 having a display device and an operating unit 504 having a keyboard.
  • FIG. 2 is a block diagram showing the configuration of the medication auditing support system 10.
  • the controlling machine 500 is electrically connected to the dose-packaging machine 100, the conveying machine 200, the auditing machine 300, the displaying unit 502 and the operating unit 504.
  • the controlling machine 500 includes: a processing unit 506 configured to perform various kinds of controls; a storing unit 508 configured to store various kinds of data; and a communication interface 510 configured to perform data communication with an external network.
  • the controlling machine 500 is connected to the receipt computer via the communication interface 510.
  • the dose-packaging machine 100 has a casing 102.
  • the dose-packaging machine 100 is provided with a plurality of feeders 104 for storing a plurality of medications.
  • the plurality of feeders 104 are arranged in a vertical direction (longitudinal direction) and in a horizontal direction (lateral direction).
  • the plurality of feeders 104 can be arranged on a back side when seen from a front.
  • the feeders 104 can drop the medications stored therein one by one, to the lower side.
  • the controlling machine 500 can select necessary feeders 104 based on prescription data and cause the feeders to drop medication corresponding to one sachet to the lower side.
  • Each feeder 104 can include: a cassette configured to accommodate medication; and a shooter or the like configured to guide the medication from the cassette to the lower side.
  • the dose-packaging machine 100 is provided with a hopper 106 on the lower side of the feeders 104.
  • the hopper 106 is a tubular member having openings on both sides. The opening on the upper side is wide, and the opening on the lower side is narrower than the upper-side opening.
  • the hopper 106 collects medication dropped from feeders 104 on the upper side thereof and gathers the medication in one place on the lower side thereof.
  • a feeding pipe 108 is provided on the lower side of the hopper 106.
  • the dose-packaging machine 100 has a packaging mechanism 110 on the lower side of the feeding pipe 108. Tablets gathered by the hopper 106 are guided to the packaging mechanism 110 by the feeding pipe 108.
  • the feeding pipe 108 is a tube-shaped member that extends in a vertical direction. A cross-section of the feeding pipe 108 may be in a circular shape or in an oval shape. Further, the feeding pipe 108 may be in a cylindrical shape or in a frustum shape. The shape of the feeding pipe 108 is not especially limited so long as the feeding pipe 108 can guide tablets to the packaging mechanism 110.
  • the packaging mechanism 110 is provided with a supplying mechanism 114 configured to feed packaging paper 112 and a heat sealing mechanism 116 configured to heat-fuse the packaging paper 112.
  • the packaging paper 112 is formed of a heat fusible material.
  • the packaging paper 112 is in a state where a continuous sheet is two-folded in a lateral direction, and then wound in a roll shape.
  • the heat sealing mechanism 116 has, for example, a vertical heating head (longitudinal heating head) 116A that is vertically (longitudinally) arranged and a horizontal heating head (lateral heating head) 116B that is horizontally (laterally) arranged.
  • the heat sealing mechanism 116 can form vertical seal portions (longitudinal seal portions) and horizontal seal portions (lateral seal portions) on the packaging paper 112 that is being conveyed.
  • the supplying mechanism 114 includes, for example, a shaft configured to hold the packaging paper 112 in a roll shape, a drive motor configured to rotate the shaft and the like.
  • the controlling machine 500 can intermittently or continuously drive the drive motor to rotate.
  • the packaging paper 112 is conveyed in a state in which the folded portion is located on the lower side.
  • the vertical seal portion is formed on the packaging paper 112 by the vertical heating head 116A of the heat sealing mechanism 116.
  • the packaging paper 112 is in a state of being half closed.
  • the half-closed packaging paper 112 passes below the feeding pipe 108.
  • Medication corresponding to one sachet is supplied to the half-closed packaging paper 112 from the feeding pipe 108.
  • the horizontal seal portion is formed by the horizontal heating head 116B of the heat sealing mechanism 116.
  • the heat sealing mechanism 116 heat fuses packaging paper 112 to form packaging sachets 118 which individually packages the medication.
  • the dose-packaging machine 100 discharges continuous packaging sachets 118 from a discharge port 120.
  • the vertical heating head 116A of the heat sealing mechanism 116 may be provided with a perforation forming machine (not shown).
  • the perforation forming machine is provided, for example, with a plurality of blades or the like capable of penetrating the packaging paper 112.
  • the perforation forming machine can form perforations on the vertical seal portion.
  • the packaging mechanism 110 may include a print head 122.
  • the print head 122 performs printing on an area in the packaging paper 112 where packaging sachets are formed, after the packaging paper 112 passes through the heat sealing mechanism 116.
  • Printed information includes, for example, a patient's name, a name and usage of the medication, and the like.
  • the auditing machine 300 has a casing 301.
  • the casing 301 is provided with an introduction port 302 configured to receive the continuous packaging sachets 118 and a discharge port 334 configured to discharge the continuous packaging sachets 118.
  • the auditing machine 300 is provided with a pair of first conveying rollers 304 on the upstream side and a pair of second conveying rollers 306 on the downstream side.
  • the first conveying rollers 304 and the second conveying rollers 306 sandwich (hold therebetween) the horizontal seal portions of the continuous packaging sachets 118 from upward and downward directions. By sandwiching the horizontal seal portions, it is possible to avoid medication from being caught between the first conveying rollers 304 and the second conveying rollers 306 so that the medication is not damaged.
  • An imaging area is provided on a conveying path between the first conveying rollers 304 and the second conveying rollers 306.
  • a first camera 308 is arranged on the upper side of the conveying path
  • a second camera 310 is arranged on the lower side of the conveying path.
  • the first camera 308 and the second camera 310 are, for example, digital cameras.
  • a plurality of light sources 312 are arranged on the upper and lower sides of the conveying path. On the upper side of the conveying path, four light sources 312 are arranged at equal intervals on the same circumference around an imaging optical axis of the first camera 308. Similarly, on the lower side of the conveying path, four light sources 312 are arranged at equal intervals on the same circumference around an imaging optical axis of the second camera 310.
  • the imaging area of the conveying path is formed of a transparent member.
  • the first camera 308 and the second camera 310 image medications packaged in each conveyed packaging sachet 118 from the upward and downward directions.
  • the packaging sachet 118 is in a horizontal state.
  • the horizontal state means that a plane surrounded by the vertical seal portions, horizontal seal portions and folded portion of each packaging sachet 118 is horizontal.
  • a spreading mechanism (not shown) is provided in the imaging area.
  • the spreading mechanism eliminates overlap among medications in each packaging sachet 118. By causing the spreading mechanism to operate, the first camera 308 and the second camera 310 can accurately image the medications in each packaging sachet 118.
  • a guide 314 is arranged downstream of the imaging area.
  • the guide 314 guides the packaging sachets 118 to the conveying path on the lower side.
  • the auditing machine 300 is provided with a label printer mechanism 316.
  • a third camera 330 is arranged at a position facing the label printer mechanism 316, with the conveying path interposed between the third camera 330 and the label printer mechanism 316.
  • the third camera 330 images perforations formed on the vertical seal portions of each packaging sachet 118 to detect positions of the perforations. Positions where labels are attached are adjusted based on the detected positions of the perforations.
  • the label printer mechanism 316 includes: a supplying mechanism 320 configured to feed labeled backing paper 318; a label printer 322; a label peeling mechanism 324; and a winding mechanism 326 configured to wind the backing paper.
  • the supplying mechanism 320 includes, for example, a shaft configured to hold the labeled backing paper 318 in a roll shape, a drive motor configured to rotate the shaft, and the like.
  • the label printer 322 includes, for example, a thermal head printer.
  • the winding mechanism 326 includes a shaft configured to wind the backing paper 318 that is unlabeled, a drive motor configured to rotate the shaft, and the like.
  • the label peeling mechanism 324 includes a pair of belt conveying mechanisms. The labeled backing paper 318 is caused to pass through between the pair of belt conveying mechanisms and folded so as to peel a printed label from the backing paper. The peeled label is attached to the packaging sachet 118.
  • the print head 122 of the packaging mechanism 110 and the label printer mechanism 316 of the auditing machine 300 can be used in parallel with each other, or only one of the print head 122 and print head 122 can be used.
  • a pair of third conveying rollers 332 is arranged downstream of the label printer mechanism 316.
  • the third conveying rollers 332 discharge the continuous packaging sachets 118 to which the labels are attached, from the discharge port 334.
  • the packaging sachets 118 discharged from the discharge port 334 are accommodated into an accommodation box 400.
  • a winding device may be arranged instead of the accommodation box 400.
  • the winding device includes a winding shaft, a drive motor configured to drive the winding shaft, and the like.
  • the conveying machine 200 has a casing 201.
  • the casing 201 is provided with an introduction port 202 configured to receive the continuous packaging sachets 118 and a discharge port 224 configured to discharge the continuous packaging sachets 118.
  • the conveying machine 200 is provided with a pair of first conveying rollers 204, a turret mechanism 208 and a pair of second conveying rollers 206 in this order from the upstream side toward the downstream side.
  • the turret mechanism 208 is provided with a disk-shaped turn table 210, and a table rotating shaft 212 configured to rotatably support the turn table 210.
  • the table rotating shaft 212 is connected to a drive motor (not shown).
  • the turn table 210 is provided with a plurality of rotating shafts (a winding rotating shaft 214 and a feeding rotating shaft 216).
  • the winding rotating shaft 214 and the feeding rotating shaft 216 are arranged in point symmetry with each other, with the table rotating shaft 212 as a center.
  • Each of the winding rotating shaft 214 and the feeding rotating shaft 216 is connected to a drive motor (not shown).
  • the winding rotating shaft 214 and the feeding rotating shaft 216 can rotate clockwise and counterclockwise by the drive motor.
  • the turret mechanism 208 is a mechanism configured to switch positions of the winding rotating shaft 214 and the feeding rotating shaft 216 by rotating the turn table 210.
  • the structure of the turn table 210 is not limited if it is possible to switch the positions.
  • the turret mechanism may have a structure provided with a linear arm, an arm rotating shaft configured to rotatably support the center of the arm, and rotating shafts configured to wind and feed packaging sachets, the rotating shafts being on both ends of the linear arm.
  • the winding rotating shaft 214 is located on a side near to the dose-packaging machine 100.
  • the position is referred to as a winding position.
  • the winding rotating shaft 214 can rotate clockwise to wind packaging sachets 118 discharged from the dose-packaging machine 100 in a roll shape via the first conveying rollers 204.
  • the packaging sachets 118 discharged from the dose-packaging machine 100 are wound by the winding rotating shaft 214 corresponding to one rotating shaft among the plurality of rotating shafts (the winding rotating shaft 214 and the feeding rotating shaft 216).
  • the feeding rotating shaft 216 is located on a side near to the auditing machine 300.
  • the position is referred to as a feeding position.
  • the feeding rotating shaft 216 can rotate counterclockwise to feed other packaging sachets 118 wound in a roll shape to the auditing machine 300 via the second conveying rollers 206 and the discharge port 224.
  • the packaging sachets 118 discharged from the dose-packaging machine 100 are wound by the feeding rotating shaft 216 corresponding to one rotating shaft among the plurality of rotating shafts (the winding rotating shaft 214 and the feeding rotating shaft 216).
  • outer circumferences of the first conveying rollers 204 and the second conveying rollers 206 are configured with soft members (sponges, brushes or the like) so as not to damage medication packaged in packaging sachets 118.
  • All packaging sachets 118 are fed from the feeding rotating shaft 216 that is at the feeding position. Dividing and packaging sachets 118 wound by the winding rotating shaft 214 that is at the winding position are targeted by the next feeding.
  • packaging sachets 118 are wound around the winding rotating shaft 214 until a certain diameter is reached, or winding is ended in a state that packaging sachets 118 have not been wound until the certain diameter is reached.
  • the turn table 210 is caused to rotate at 180° around the table rotating shaft 212.
  • the winding rotating shaft 214 moves to the feeding position, and the feeding rotating shaft 216 moves to the winding position. Having moved to the feeding position, the winding rotating shaft 214 becomes the feeding rotating shaft 216. On the other hand, having moved to the winding position, the feeding rotating shaft 216 becomes the winding rotating shaft 214.
  • the feeding rotating shaft 216 By rotating the feeding rotating shaft 216 counterclockwise, the packaging sachets 118 that have been already wound are unwound and fed to the auditing machine 300.
  • the winding rotating shaft that has fed the packaging sachets 118 rotates clockwise and winds packaging sachet 118 discharged from the dose-packaging machine 100.
  • the conveying machine 200 can be provided with a diameter detecting sensor 220 for a wound roll at the winding position, and a diameter detecting sensor 222 for a feed roll at the feeding position.
  • a roll diameter of the wound packaging sachets 118 is acquired at the winding position by the diameter detecting sensor 220.
  • a winding amount of packaging sachets 118 is calculated.
  • a roll diameter of the packaging sachets 118 at the feeding position is acquired by the diameter detecting sensor 222.
  • a feeding amount of the packaging sachets 118 is calculated.
  • a timing to drive the turn table 210 can be controlled based on the winding amount and the feeding amount of the packaging sachets 118.
  • the diameter detecting sensors 220 and 222 are, for example, non-contact type ultrasonic sensors, laser sensors or the like.
  • the dose-packaging machine 100 and the auditing machine 300 are different in processing speed.
  • the processing speed means a length of packaging sachets 118 discharged from each of the dose-packaging machine 100 and the auditing machine 300 per unit time.
  • the processing speed of the auditing machine 300 is slower than the processing speed of the dose-packaging machine 100.
  • the conveying machine 200 shown in Figure 1 can wind packaging sachets 118 at a speed suitable for the processing speed of the dose-packaging machine 100 and feed packaging sachets 118 to the auditing machine 300 at the processing speed of the auditing machine 300.
  • the turret mechanism 208 functions as a buffer unit.
  • the buffer unit has a function of temporarily storing packaging sachets 118, and the structure is not limited so long as the function can be realized.
  • the buffer unit is effectively works to adjust the difference between the processing speeds of the dose-packaging machine 100 and the auditing machine 300 while being conveyed.
  • the maximum permissible range means a maximum value of a storage amount of packaging sachets 118, and the maximum permissible range can be arbitrarily decided in advance according to the structure of the conveying machine 200.
  • the amount of the packaging sachets 118 reaches the maximum permissible range, temporarily stop the operation of the dose-packaging machine 100.
  • the temporary stop of the operation can suppress the packaging sachets 118 from getting stuck in the dose-packaging machine 100.
  • FIG 4 is a block diagram of the controlling machine 500.
  • the controlling machine 500 is provided with the processing unit 506 and the storing unit 508.
  • the processing unit 506 is provided with a dose-packaging machine controlling unit 512 configured to control the dose-packaging machine 100 (not shown), a conveying machine controlling unit 520 configured to control the conveying machine 200 (not shown) and an auditing machine controlling unit 530 configured to control the auditing machine 300 (not shown).
  • Functions of these components are realized by a device, such as a CPU (Central Processing Unit) and various kinds of electronic circuits, referring to data stored in an EEPROM (Electronically Erasable and Programmable Read Only Memory: a non-transitory recording medium) or the like. Further, the functions of these components are performed by executing a medication test supporting program stored in an ROM (Read Only Memory: a non-transitory recording medium) or the like. At the time of processing, a RAM (Random Access Memory) or the like is used as a temporary storage area and a working area.
  • the devices such as the CPU are not shown in Figure 4 .
  • the dose-packaging machine controlling unit 512 is provided, for example, with a feeder unit 512A and a packaging unit 512B.
  • the feeder unit 512A controls the operation of feeders 104 of the dose-packaging machine 100 based on prescription data.
  • the packaging unit 512B controls the operations of the supplying mechanism 114 and heat sealing mechanism 116 of the packaging mechanism 110.
  • the conveying machine controlling unit 520 is provided with, for example, a buffer controlling unit 520A, a conveying unit 520B and a warning unit 520C.
  • the buffer controlling unit 520A controls the operation of the turret mechanism 208.
  • the conveying unit 520B controls the operations of the first conveying rollers 204 and the second conveying rollers 206.
  • the warning unit 520C issues a stop signal to the dose-packaging machine controlling unit 512.
  • the auditing machine controlling unit 530 is provided, with an imaging unit 530A, an auditing unit 530B, a printing unit 530C and a conveying unit 530D.
  • the imaging unit 530A controls the first camera 308 and the second camera 310 to image audit-target medication packaged in each packaging sachet 118 and acquires an imaged image.
  • the auditing unit 530B outputs information showing whether the audit-target medication shown by the imaged image and medication shown by an image obtained based on the prescription data are the same or not.
  • the printing unit 530C controls the label printer mechanism 316 to perform printing on a label and paste the printed label to the packaging sachet 118.
  • the conveying unit 530D controls the operations of the first conveying rollers 304, the second conveying rollers 306 and the third conveying rollers 332.
  • the function of the processing unit 506 can be realized using various kinds of processors.
  • the various kinds of processors include, for example, a CPU (Central Processing Unit) which is a general-purpose processor configured to execute software (a program) to realize various kinds of functions.
  • a programmable logic device PLD which is a processor the circuit configuration of which is changeable after production, such as an FPGA (Field Programmable Gate Array), is also included.
  • a dedicated electrical circuit which is a processor having a circuit configuration specially designed to execute particular processing, such as ASIC (Application Specific Integrated Circuit), is also included in the various kinds of processors described above.
  • each unit may be realized by one processor or may be realized by a combination of a plurality of processors. Further, a plurality of functions may be realized by one processor.
  • a processor includes a combination of one or more CPU's and software, and this processor realizes the plurality of functions as represented by a computer such as a client and a server.
  • a processor that realizes functions of a whole system by one IC (Integrated Circuit) chip is used, as represented by System On Chip (SoC) or the like.
  • SoC System On Chip
  • a computer-readable code of a program that causes a dispensing auditing support device (a computer) to execute a dispensing auditing support method according to the present invention is recorded to a non-transitory recording medium such as a ROM (Read Only Memory) not shown.
  • the storing unit 508 includes a non-transitory recording medium such as a CD (Compact Disk), a DVD (Digital Versatile Disk), a hard disk and various kinds of semiconductor memories, and a controlling unit thereof.
  • the storing unit 508 can store, for example, prescription data 508A, medication data 508B, medication images 508C, an audit result 508D and the like.
  • the prescription data 508A is information related to medical prescription and includes, for example, a patient's name, and a name, usage and amount of the medication.
  • the medication data 508B includes an external appearance image of the medication, and a type, shape and size of the medication.
  • the medication images 508C are images of the audit-target medication.
  • the audit result 508D is information showing an audit result created by the processing unit 506.
  • Medications are prepared in the plurality of feeders 104, and the packaging paper 112 is prepared in the supplying mechanism 114.
  • the feeder unit 512A controls the feeders 104 based on the prescription data 508A, and the feeders 104 supply medication corresponding to one sachet to the packaging mechanism 110.
  • the packaging unit 512B controls the packaging mechanism 110.
  • Pieces of packaging paper 112 are intermittently conveyed from the supplying mechanism 114, and the heat sealing mechanism 116 forms the vertical seal portions on each piece of packaging paper 112 and forms perforations.
  • the medication is supplied to the packaging paper 112 from the feeding pipe 108.
  • the pieces of packaging paper 112 are intermittently conveyed, and the heat sealing mechanism 116 forms the horizontal seal portions on each piece of packaging paper 112.
  • the dose-packaging machine 100 discharges packaging sachets 118.
  • the conveying machine 200 receives the packaging sachets 118 from the introduction port 202.
  • the conveying unit 520B controls the first conveying rollers 204 to convey the packaging sachets 118 to the turret mechanism 208.
  • the buffer controlling unit 520A controls the turret mechanism 208.
  • the winding rotating shaft 214 is rotated at the winding position, and the packaging sachets 118 are wound at a speed suitable for the processing speed of the dose-packaging machine 100.
  • the turn table 210 is rotated.
  • the wound packaging sachets 118 are moved to the feeding position.
  • the packaging sachets 118 are unwound at a speed suitable for the processing speed of the auditing machine 300 by the feeding rotating shaft 216.
  • the conveying unit 520B controls the second conveying rollers 206 to feed the packaging sachets 118 to the auditing machine 300 at a speed suitable for the auditing machine 300.
  • the packaging sachets 118 are fed to the auditing machine 300. While the packaging sachets 118 are being fed, the packaging sachets 118 are wound by the winding rotating shaft 214.
  • the warning unit 520C calculates the storage amount of packaging sachets 118 from a signal of the diameter detecting sensor 220.
  • the warning unit 520C issues a stop signal as necessary.
  • the auditing machine 300 receives the packaging sachets 118 from the introduction port 302.
  • the conveying unit 530D controls the first conveying rollers 304 and the second conveying rollers 306 to convey the packaging sachets 118 to the imaging area.
  • the imaging unit 530A controls the light sources 312, the first camera 308 and the second camera 310 to image medication of each packaging sachet 118 from the upward and downward directions and acquires the medication images 508C.
  • the auditing unit 530B acquires the medication data 508B including images, from the prescription data 508A.
  • the auditing unit 530B determines whether the audit-target medication is the same as medication shown in the prescription data 508A or not from the medication data 508B and the medication images 508C, and outputs information about the audit result 508D.
  • the printing unit 530C controls the label printer mechanism 316 to attach a label on which the prescription data and the information obtained by the auditing unit 530B are printed, to the packaging sachet 118.
  • the conveying unit 530D controls the third conveying rollers 332.
  • the third conveying rollers 332 discharge labeled packaging sachets 118 into the accommodation box 400 via the discharge port 334.
  • the conveying machine 200 adjusts the difference between the processing speeds of the dose-packaging machine 100 and the auditing machine 300.
  • the controlling machine 500 instructs the dose-packaging machine 100 to package medication, based on the audit result 508D of the auditing machine 300.
  • the packaging sachet 118 determined not to correspond (referred to as an improper packaging sachet) is not used.
  • the controlling machine 500 controls the dose-packaging machine 100 based on the audit result 508D, and the dose-packaging machine 100 newly packages medication in the packaging paper 112 based on the prescription data of the improper packaging sachet in order to make up for the shortage of the packaging sachets 118.
  • shortage of packaging sachets 118 is automatically supplemented.
  • FIG 5 is a partially enlarged diagram of the auditing machine 300.
  • the same components as those of the auditing machine 300 shown in Figure 1 are given the same reference numerals, and description of the components is omitted.
  • the auditing machine 300 is provided with a passage detecting sensor 342 and a perforation forming machine 344 in this order from the upstream to the downstream, between the discharge port 334 and the third conveying rollers 332.
  • the dose-packaging machine 100 is provided with the perforation forming machine.
  • the perforations between the packaging sachets 118 may cause unintended cutting of the packaging sachets 118 during conveyance in the dose-packaging machine 100, the conveying machine 200 and the auditing machine 300.
  • the packaging sachets 118 may get stuck in the dose-packaging machine 100, the conveying machine 200 and the auditing machine 300.
  • the jam may cause failure of the dose-packaging machine 100, the conveying machine 200 and the auditing machine 300.
  • the throughput of the medication auditing support system 10 decreases.
  • the auditing machine 300 shown in Figure 5 is provided with the perforation forming machine 344 configured to form perforations on the continuous packaging sachets 118 that have been audited.
  • the perforation forming machine 344 of the auditing machine 300 can suppress the packaging sachets 118 from being cut due to the perforations while being conveyed. It is preferable that the perforation forming machine 344 is arranged upstream or downstream of the third conveying rollers 332 which are discharge rollers. Since the packaging sachets 118 on which perforations are formed are discharged from the downstream discharge port 334, tension applied to the perforations of the packaging sachets 118 can be reduced. As a result, it is possible to suppress unintended cutting of the packaging sachets 118.
  • the third camera 330 detects vertical seal portions. Since each packaging sachet 118 is conveyed by the conveying unit 530D based on the position of the vertical seal portion, the packaging sachets 118 can be aligned with the positions where labels are attached and perforation forming positions.
  • the perforation forming machine 344 includes a first perforation blade (not shown) having a plurality of protruding edges and a second perforation blade (not shown) having holes to receive the protruding edges of the first perforation blade.
  • the vertical seal portion of each packaging sachet 118 is held between the first perforation blade and the second perforation blade so that perforations are formed on the vertical seal portion.
  • the passage detecting sensor 342 shown in Figure 5 is a detector configured to detect a movement of one packaging sachet 118.
  • the passage detecting sensor 342 can detect a label attached on the packaging sachet 118 and confirm passage of the one packaging sachet 118.
  • a reflection-type sensor and a transmission-type sensor is applicable.
  • each of the reflection-type sensor and the transmission-type sensor is provided with a light emitting unit and a light receiving unit.
  • the auditing machine controlling unit 530 detects passage of one packaging sachet 118, information is transmitted to the conveying machine controlling unit 520. Based on a result of the passage detecting sensor 342, the conveying machine controlling unit 520 controls the conveying machine 200.
  • the conveying machine 200 receives the one packaging sachet 118 from the dose-packaging machine 100.
  • FIG. 6 is a partially enlarged diagram of the dose-packaging machine 100 and the conveying machine 200.
  • the dose-packaging machine 100 is provided with a switching mechanism 130 configured to switch between routes of packaging sachets 118.
  • the switching mechanism 130 is provided with an introduction port 132 for packaging sachets 118, a discharge port 134 for packaging sachets 118, and a movable conveying path 136 between the introduction port 132 and the discharge port 134.
  • the movable conveying path 136 has a fulcrum 138 on the dose-packaging machine 100 side.
  • the movable conveying path 136 can move up and down within a predetermined range, with the fulcrum 138 as a center.
  • the route can be switched to a route to feed the packaging sachet 118 to a place other than the auditing machine 300.
  • a second embodiment is described with reference to Figures 7 to 10 .
  • the same reference numerals are given, and detailed description of the components is omitted.
  • a configuration of a buffer unit that is different from the other embodiments is mainly described.
  • Figure 7 is a schematic configuration diagram of the conveying machine 200 of the medication auditing support system 10.
  • the dose-packaging machine 100, the auditing machine 300 and the controlling machine 500 are omitted.
  • the conveying machine 200 is provided with the casing 201 having the introduction port 202 and the discharge port 224, and the pair of first conveying rollers 204, the pair of second conveying rollers 206, a dancer roller mechanism 230 and a pair of third conveying rollers 240 in this order from the upstream toward the downstream side.
  • the dancer roller mechanism 230 is provided with two guide rollers 232 and a dancer roller 234 arranged between the two guide rollers 232.
  • the dancer roller mechanism 230 is a mechanism configured to change a relative distance between the guide rollers 232 and the dancer roller 234.
  • the dancer roller 234 is movably configured.
  • the two guide rollers 232 are fixed, and the dancer roller 234 can move in the upward and downward directions.
  • a rotating shaft supporting the dancer roller 234 is movable up and down, and can be fixed to a frame or the like in a rotatable state.
  • the dancer roller mechanism 230 functions as a buffer unit. By adjusting the amount of packaging sachets 118 accumulated in the dancer roller mechanism 230, it is possible to adjust the difference between the processing speeds of the dose-packaging machine 100 (not shown) and the auditing machine 300.
  • the storage amount of packaging sachets 118 is increased by lowering the dancer roller 234. It is possible to feed the packaging sachets 118 at a conveyance speed suitable for the processing speed of the auditing machine 300 by the third conveying rollers 240.
  • the buffer controlling unit 520A shown in Figure 4 controls the operation of the dancer roller mechanism 230.
  • the dose-packaging machine controlling unit 512 can stop the dose-packaging machine 100.
  • the dose-packaging machine 100 is not stopped as necessary.
  • FIG 8 is a schematic configuration diagram of the conveying machine 200 according to a modification of the second embodiment.
  • the dancer roller mechanism 230 of the conveying machine 200 is provided with four guide rollers 232 and three dancer rollers 234.
  • the dancer roller mechanism 230 can accumulate more packaging sachets 118 because of a relationship with the operation of the dose-packaging machine 100. Therefore, it is preferable that the guide rollers 232 and the dancer rollers 234 are arranged at a plurality of stages as shown in Figure 8 .
  • the plurality of stages means that the dancer roller mechanism 230 is provided with two or more dancer rollers 234. Though the four guide rollers 232 and the three dancer rollers 234 are shown in Figure 8 , the numbers are not limited thereto.
  • the numbers of guide rollers 232 and dancer rollers 234 can be decided in consideration of the processing speeds of the dose-packaging machine 100 and the auditing machine 300.
  • Figure 9 is an explanatory diagram showing an operation of the dancer roller mechanism 230 according to the modification of the second embodiment.
  • Reference numeral 901 in Figure 9 shows a state in which all the three dancer rollers 234 are located at the highest points. The packaging sachets 118 are not conveyed.
  • Reference numeral 902 in Figure 9 shows a state in which the packaging sachets 118 start to be conveyed from the dose-packaging machine 100 (not shown) to the dancer roller mechanism 230 of the conveying machine 200 (not shown).
  • the dancer roller 234 near to the auditing machine 300 (not shown) is moved toward the lower side.
  • the packaging sachets 118 start to be accumulated.
  • Reference numeral 903 in Figure 9 shows a state in which the packaging sachets 118 are continuously being conveyed to the dancer roller mechanism 230.
  • the dancer roller 234 nearest to the auditing machine 300 reaches the lowest point, the dancer roller 234 in the center is moved toward the lower side.
  • the packaging sachets 118 are further accumulated in the dancer roller mechanism 230.
  • Reference numeral 904 in Figure 9 shows a state in which the packaging sachets 118 are continuously being conveyed to the dancer roller mechanism 230.
  • the dancer roller 234 near to the auditing machine 300 and the dancer roller 234 in the center reach the lowest point, the dancer roller 234 near to the dose-packaging machine 100 is moved toward the lower side.
  • the dancer roller mechanism 230 accumulates the packaging sachets 118 by an amount of the maximum permissible range.
  • Reference numeral 905 in Figure 9 shows a state in which conveyance of packaging sachets 118 from the dose-packaging machine 100 is stopped, and the packaging sachets 118 accumulated in the dancer roller mechanism 230 start to be conveyed to the auditing machine 300.
  • the dancer roller 234 near to the auditing machine 300 is moved toward the upper side, and the accumulated packaging sachets 118 are conveyed to the auditing machine 300.
  • Reference numeral 906 in Figure 9 shows a state in which the packaging sachets 118 are continuously being conveyed to the auditing machine 300.
  • the dancer roller 234 near to the auditing machine 300 reaches the highest point, the dancer roller 234 in the center is moved toward the upper side, and the accumulated packaging sachets 118 are conveyed to the auditing machine 300.
  • FIG 10 is an explanatory diagram showing another operation according to the modification of the second embodiment.
  • the dancer roller 234 near to the auditing machine 300 (not shown) is moved toward the upper side so that the packaging sachets 118 accumulated in the dancer roller mechanism 230 are conveyed to the auditing machine 300.
  • the dancer roller 234 near to the dose-packaging machine 100 is moved toward the lower side so that the packaging sachets 118 conveyed from the dose-packaging machine 100 are accumulated in the dancer roller mechanism 230.
  • a third embodiment is described with reference to Figure 11 .
  • components having the same operation as the first and second embodiments the same reference numerals are given, and detailed description of the components is omitted.
  • a configuration of a buffer unit that is different from the other embodiments is mainly described.
  • Figure 11 is a schematic configuration diagram of the conveying machine 200 of the medication auditing support system 10.
  • the dose-packaging machine 100, the auditing machine 300 and the controlling machine 500 are omitted.
  • the conveying machine 200 is provided with the casing 201 having the introduction port 202 and the discharge port 224, and the pair of first conveying rollers 204, the pair of second conveying rollers 206, a folding mechanism 250, the pair of third conveying rollers 240 and a pair of fourth conveying rollers 246, in this order from the upstream toward the downstream side.
  • the folding mechanism 250 is provided with a pair of movable conveying rollers 252 and a position detecting sensor 254.
  • the folding mechanism 250 functions as a buffer unit.
  • the folding mechanism 250 is a mechanism configured to form a folding edge on packaging sachets 118 for each predetermined length of the packaging sachets 118, to stack the packaging sachets 118.
  • the predetermined length can be appropriately set according to the size and the like of the conveying machine 200.
  • the pair of movable conveying rollers 252 can reciprocate in the horizontal direction.
  • the packaging sachets 118 conveyed from the dose-packaging machine 100 pass through the pair of movable conveying rollers 252 that continuously reciprocate in the horizontal direction, and are fed to the lower side of the conveying machine 200. As a result, the packaging sachets 118 are accumulated in the folding mechanism 250, being stacked in a zigzag shape by the movable conveying rollers 252.
  • the packaging sachets 118 are conveyed to the auditing machine 300 (not shown) by the third conveying rollers 240 and the fourth conveying rollers 246.
  • the position detecting sensor 254 can detect whether the packaging sachets 118 have reached the maximum permissible range or not.
  • a tension adjusting mechanism (not shown) in the conveying machine 200 to impart certain tension to packaging sachets 118.
  • the tension adjusting mechanism is operated to impart the certain tension to the packaging sachets 118.
  • the packaging sachets 118 are pulled to the conveying machine 200 and received into the conveying machine 200. Therefore, the conveying machine 200 can receive the packaging sachets 118 in synchronization with discharge of the packaging sachets 118 from the dose-packaging machine 100.
  • a dancer roller is applicable as the tension adjusting mechanism.
  • the tension on the packaging sachets 118 is decided.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)

Claims (9)

  1. Système de prise en charge de vérification de médicament (10) comprenant :
    une machine de conditionnement sous forme de doses (100) configurée pour conditionner un médicament sur la base de données de prescription et pour évacuer des sachets de conditionnement continus (118) ;
    une machine de transport (200) configurée pour recevoir les sachets de conditionnement continus (118) évacués à partir de la machine de conditionnement (100) et pour alimenter les sachets de conditionnement continus (118) ;
    une machine de vérification (300) configurée pour recevoir les sachets de conditionnement continus (118) alimentés à partir de la machine de transport (200) et pour vérifier le médicament conditionné dans les sachets de conditionnement (118) sur la base des données de prescription ;
    le système de prise en charge de vérification de médicament étant caractérisé en ce que
    une machine de commande (500) est configurée pour commander la machine de conditionnement sous forme de doses (100), la machine de transport (200) et la machine de vérification (300), dans lequel
    la machine de transport (200) comprend une unité de tampon (208, 230, 250) configurée pour stocker les sachets de conditionnement continus (118), et
    lorsqu'une quantité des sachets de conditionnement (118) stockés dans l'unité de tampon (208, 230, 250) atteint une plage maximum admissible, la machine de commande (500) arrête temporairement un fonctionnement de la machine de conditionnement sous forme de doses (100).
  2. Système de prise en charge de vérification de médicament selon la revendication 1, dans lequel
    l'unité de tampon inclut un mécanisme à rouleau danseur (230).
  3. Système de prise en charge de vérification de médicament (10) selon la revendication 1, dans lequel
    l'unité de tampon inclut un mécanisme de tourelle (208) comprenant une pluralité d'arbres rotatifs (214, 216) et configuré pour commuter des positions de la pluralité d'arbres rotatifs (214, 216), le mécanisme de tourelle (208) étant configuré pour enrouler une pièce des sachets de conditionnement (118) évacués à partir de la machine de conditionnement sous forme de doses (100) par l'un (214) des arbres rotatifs et alimenter une autre partie des sachets de conditionnement (118) vers la machine de vérification (300) via un autre (214) des arbres rotatifs.
  4. Système de prise en charge de vérification de médicament (10) selon l'une quelconque des revendications 1 à 3, dans lequel
    la machine de transport (200) reçoit les sachets de conditionnement (118) en synchronisation avec une évacuation des sachets de conditionnement (118) à partir de la machine de conditionnement sous forme de doses (100).
  5. Système de prise en charge de vérification de médicament (10) selon la revendication 4, dans lequel
    la machine de transport (200) imprime une certaine tension aux sachets de conditionnement continus (118) et ne reçoit que les sachets de conditionnement (118) évacués à partir de la machine de conditionnement (100).
  6. Système de prise en charge de vérification de médicament (10) selon la revendication 5, comprenant un détecteur (342) configuré pour détecter un mouvement d'un certain des sachets de conditionnement continus (118) évacué à partir de la machine de conditionnement (100), dans lequel
    la machine de transport (200) reçoit le certain des sachets de conditionnement (118) sur la base d'un résultat du détecteur (342).
  7. Système de prise en charge de vérification de médicament (10) selon l'une quelconque des revendications 1 à 6, dans lequel
    la machine de commande (500) ordonne à la machine de conditionnement sous forme de doses (100) de conditionner le médicament sur la base d'un résultat de vérification de la machine de vérification (300).
  8. Système de prise en charge de vérification de médicament (10) selon l'une quelconque des revendications 1 à 7, comprenant
    une machine de formation de perforation (344) configurée pour former des perforations sur les sachets de conditionnement continus (118) qui ont été vérifiés par la machine de vérification (300).
  9. Système de prise en charge de vérification de médicament (10) selon l'une quelconque des revendications 1 à 8, dans lequel
    la machine de conditionnement (100) comprend un mécanisme de commutation (130) configuré pour commuter entre un trajet pour alimenter les sachets de conditionnement (118) vers la machine de vérification (300) et un trajet pour distribuer les sachets de conditionnement (118) vers un emplacement autre que la machine de vérification (300).
EP18905390.3A 2018-02-09 2018-12-27 Système de prise en charge de vérification de médicament Active EP3750521B1 (fr)

Applications Claiming Priority (2)

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JP2018022236 2018-02-09
PCT/JP2018/048330 WO2019155788A1 (fr) 2018-02-09 2018-12-27 Système de prise en charge de vérification de médicament

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JP7301988B2 (ja) * 2019-09-10 2023-07-03 富士フイルム富山化学株式会社 搬送機、及び薬剤監査支援システム

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Publication number Priority date Publication date Assignee Title
JPH07265382A (ja) * 1994-03-29 1995-10-17 Tokyo Shokai:Kk 薬包体の監査システム
JP3779773B2 (ja) * 1996-07-30 2006-05-31 高園産業株式会社 収納体内の薬剤の検査装置及び収納体内の薬剤の検査方法
JPH11309198A (ja) * 1999-03-23 1999-11-09 Yuyama Seisakusho:Kk 薬剤包装機
JP2001212207A (ja) * 2000-02-07 2001-08-07 Tosho Inc 薬剤分包機
US9334096B2 (en) * 2004-10-01 2016-05-10 Edge Medical Properties, Llc Multiple inspection system and method that inspects different medications
JP4752595B2 (ja) * 2006-04-27 2011-08-17 横浜ゴム株式会社 シート状ゴム材料の供給装置
JP5159716B2 (ja) * 2009-07-01 2013-03-13 Ｃｋｄ株式会社 Ｐｔｐシート製造装置
CN109592135B (zh) * 2012-10-03 2021-06-01 株式会社汤山制作所 药剂检查系统、卷绕装置、送料装置、及保持器
WO2016139056A1 (fr) * 2015-03-03 2016-09-09 Pfm Iberica Packaging Machinery S.A. Dispositif permettant la compensation continue d'un étirement d'un film durant un tirage applicable sur des machines à emballer
EP3275419A4 (fr) * 2015-03-23 2018-10-10 Yuyama Mfg. Co., Ltd. Dispositif d'emballage de portion de médicament
JP7023597B2 (ja) * 2016-03-28 2022-02-22 株式会社Ｓｃｒｅｅｎホールディングス 印刷装置、印刷システム、印刷方法および動作制御プログラム
KR101971319B1 (ko) 2016-05-26 2019-04-24 (주)제이브이엠 제어 장치

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EP3750521A1 (fr) 2020-12-16
JP6911160B2 (ja) 2021-07-28
JPWO2019155788A1 (ja) 2020-12-03
EP3750521A4 (fr) 2021-03-31

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