EP3573900A1 - Récipient de réception, technique de remplissage d'un récipient de réception, procédé de transport de récipients de réception et utilisation d'un récipient de réception - Google Patents

Récipient de réception, technique de remplissage d'un récipient de réception, procédé de transport de récipients de réception et utilisation d'un récipient de réception

Info

Publication number
EP3573900A1
EP3573900A1 EP17701478.4A EP17701478A EP3573900A1 EP 3573900 A1 EP3573900 A1 EP 3573900A1 EP 17701478 A EP17701478 A EP 17701478A EP 3573900 A1 EP3573900 A1 EP 3573900A1
Authority
EP
European Patent Office
Prior art keywords
lid
container
component
receptacle
closed position
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP17701478.4A
Other languages
German (de)
English (en)
Inventor
Guido VOLLRATH
Werner BRÜSTLE
Richard WIESLI
Stanko MARKOVIC
Marc Germann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nolato Treff AG
Original Assignee
Nolato Treff AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nolato Treff AG filed Critical Nolato Treff AG
Publication of EP3573900A1 publication Critical patent/EP3573900A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/16—Closures not otherwise provided for with means for venting air or gas
    • B65D51/1672—Closures not otherwise provided for with means for venting air or gas whereby venting occurs by manual actuation of the closure or other element
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D39/00—Closures arranged within necks or pouring openings or in discharge apertures, e.g. stoppers
    • B65D39/0005—Closures arranged within necks or pouring openings or in discharge apertures, e.g. stoppers made in one piece
    • B65D39/0029—Plastic closures other than those covered by groups B65D39/0011 - B65D39/0023
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D39/00—Closures arranged within necks or pouring openings or in discharge apertures, e.g. stoppers
    • B65D39/0052—Closures arranged within necks or pouring openings or in discharge apertures, e.g. stoppers made in more than one piece
    • B65D39/0076—Plastic closures other than those covered by groups B65D39/0058 - B65D39/007
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • B65B7/2821—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers applying plugs or threadless stoppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2205/00—Venting means

Definitions

  • the present invention relates to a receptacle, a method for filling receptacles, a method for transporting receptacles and the use of receptacles according to the independent claims.
  • Containers for example in the form of vials
  • EP 0 517 121 proposes a vial having two open ends. In one end, a cap is inserted. The cap has a vent channel. The vial is filled by the opposite, open side. The vorhande ⁇ ne gas exits during the filling over the vent passage of the cap. After filling, the cap is pushed further into the vial, so that the vent channel is completely in the vial and an O-ring closes the fluid connection to the environment.
  • the vial Since one side of the vial remains open, the vial is not sealed to the environment after being filled. A contact Therefore, minimizing the sample after filling can not be prevented. In addition, it can not be ensured that the vial is not contaminated before being filled by the open end.
  • the container preferably a vial, comprises a body and a lid.
  • the body has an open end and a ge ⁇ connected end.
  • the lid is at least partially insertable into the open end of the body to close the body.
  • the lid comprises at least one plastic component, which is designed such that it can be pierced by a cannula and, after removal of the cannula, is fluid-tight (ie sealed against gas and liquid passage).
  • the container is designed so that the lid can assume at least a first and a second closed position. In the first closed position, a cavity of the body can be filled with a cannula through the lid. Gas can escape from the cavity in the first closed position via at least one venting path. In the second closed position, the at least one venting path is closed.
  • a container according to the invention can be filled with the aid of a cannula, which can be pierced directly through the lid.
  • the gas present in the cavity eg air or an inert gas
  • ⁇ represents that no arises to high overpressure in the vial, which could lead to a leak or another filling by the Prevents pressure. Since the lid is introduced in the first closure position ⁇ at least partially into the container, a contamination of the cavity before filling is at least minimized. After filling, the lid is brought into the second closed position, in which the venting path is closed. In the second closed position, the cavity with the sample is hermetically separated from the environment.
  • the cover in the second locked position is further introduced into the body, as in the first shutter ⁇ position.
  • the lid can be easily brought from the first to the second closed position.
  • the lid can be manually or automatically inserted further into the container by applying pressure, in order to adopt the second closed position in which the venting path is closed.
  • the second closure position can be achieved for example by a rotation of the lid relative to the container.
  • the lid preferably has grooves with at least partially circumferential sealing surfaces.
  • the at least one venting path preferably comprises a recess in a sealing surface of a first groove.
  • a sealing surface of at least one second groove, however, is formed circumferentially.
  • the container preferably has at least one counter rib, which with the
  • Sealing surfaces of the grooves can come into operative connection.
  • the opposite occurs with the rib Dichtflä ⁇ che the first groove operatively connected.
  • the air can escape from the cavity during filling.
  • the lid is further inserted into the cavity, so that the counter rib comes into operative connection with the circumferential sealing surface of the second groove. Since this sealing surface formed circumferentially is (ie has no recess), no air can escape from the cavity. The venting path is thus closed.
  • the lid comprises a rib and the container comprises at least two counter-grooves with at least partially ⁇ circumferential sealing surfaces, wherein a sealing surface of a first counter-groove comprises a recess and a Dichtflä ⁇ che of the second counter-groove is formed circumferentially.
  • the rib in the lid can be in operative connection with the two sealing surfaces. In the first position, in turn gas can escape through the recess from the cavity.
  • the recess is present in a rib (in the lid or in the container) instead of the sealing surface of the groove.
  • the venting path comprises a bore in a side wall of the container, which can be closed from the inside by rotation of the lid. It would also be conceivable that the venting path comprises a tube in ei ⁇ nem two- or multi-part lid. A portion of the lid could be rotated relative to the at least one further part so that the tube is no longer formed throughout and a ventilation path is closed with it.
  • the cavity comprises between 0.5 and 2 ml, more preferably 1 ml.
  • Containers having such cavities have been found to be suitable for various samples.
  • Containers according to the invention can also be designed with cavities with higher or lower volumes.
  • the body is 30-60 mm, more preferably 40-55 mm, more preferably 50 mm long.
  • the lid preferably has an area which is not insertable into the body.
  • one end of the lid may have a higher radius than the part of the lid which can be introduced into the container.
  • the radius of this end is preferably the same size as an outer radius of the container at the open end, so that an outer side of the lid in the inserted state is flush with the outside of the container. This allows the lid over the ⁇ not brought range can be easily removed from the container when force can be put on the cover over a non introduced outside ⁇ page.
  • the lid can be completely inserted into the container.
  • the cover has at least one at least partially encircling retaining groove on an outer side of the region which can not be introduced into the body.
  • the circumferential or partial retaining ⁇ groove facilitates manual or mechanical removal of the lid in addition. Due to the retaining groove, an outer side of the cover in the non-insertable region has a structure which makes removal easier. In addition, for example, at an automatic distance, a counterpart to the retaining groove can be introduced into the retaining groove in order to improve a power transmission to the cover.
  • the lid has two plastic components or consists of two plastic components. The two components differ in their Shore hardness. The component with the lower Shore hardness is in an area of the lid Radially arranged within the component with the higher Shore hardness ⁇ .
  • the shore-harder component is formed in the circumferential direction without interruption at least in a region of the lid which can be introduced into the body.
  • the component with the lower Shore hardness allows Pe ⁇ penetration with the cannula and subsequent sealing against the environment, as previously described.
  • the shore harder component imparts additional stability to the lid by the uninterrupted design at least in the area which is inserted into the body. Due to the increased stability, the tightness of the lid can be increased again.
  • the contact pressure between the body and lid remains substantially the same even after prolonged storage.
  • the shore-harder component is the radially outermost layer, it ensures contact between the inner surface of the body and the outer surface of the lid, which seals the contents of the container from the outside.
  • an additional component may be present radially outward, at least in the area that is introduced into the body.
  • This layer is preferably formed from a shore-softer plastic than the circumferentially formed shore harder component.
  • the shore-softer component is preferably at least partially ⁇ in the region of the lid, which is introduced into the body, circumferentially surrounded by the shore-harder component.
  • the shore-softer component of the lid can be circumferentially surrounded by the shore-harder component over the entire length in the direction of the longitudinal axis of the container or at least at a point of the lid, which is not introduced into the body, extend radially outward.
  • the shore softer component may be EXISTING ⁇ also in the area, which is introduced into the body, only over a certain length. In one area, for example, only the shore harder component is present, which thus forms a cavity.
  • the shore softer component radially running at ⁇ game as displayed on the closed end toward the end to the outside.
  • the shore-softer component can thus be surrounded by the shore-harder component only over a certain length in the region which can be arranged within the cover.
  • the shore-harder component is a polypropylene and the shore-softer component is an elastomer.
  • shore softer components for example, thermoplastic elastomers, rubber or silicone are possible.
  • the thermoplastic elastomer preferably has a Shore hardness in the range of 35-48 Shore A, measured according to ISO 7619. An elastomer works well for the required conditions.
  • the elastomer allows penetration with the cannula. Further, the elastomer seals the passage site after removal of the cannula again.
  • Other plastics that meet the penetration and Dichtungsanfor ⁇ requirements are conceivable.
  • the body preferably has at least one conically tapering section on the outside. This conical section has the closed end.
  • the container can be automatically transferred to a correct position if the position is detected by means of the geometry. Thus it can be brought at ⁇ playing manner for a sample removal through the cannula of the container in an upright position.
  • the container may also have a different geometry.
  • the body is formed so that it has a Konizi ⁇ ity in a lower quarter of 10-15 ° and has a Koni ⁇ capacity in an upper part of 1-5 °.
  • the body preferably has an outer surface
  • a flange open at the end.
  • a flange allows easy gripping of the container with a fork-shaped support member.
  • the support member should be designed so that a distance of the tines is greater than the diameter of the container below the flange, but smaller than the diameter of the container at the flange. So the container can be inserted and lifted into the tines.
  • the flange ensures that if a lid with a larger diameter than the vial is used, no additional edge is formed by the lid.
  • the flange is preferably formed conically, with the largest diameter is arranged at the open end. This largest outer diameter of the flange should correspond to the outer diameter of the lid, so that no additional edge is created.
  • the body comprises or consists of two plastic components.
  • At least one Comp ⁇ component is fully opaque or opaque formed and arranged at the closed end of the body.
  • This at least one fully opaque or opaque component has a code, preferably ⁇ example a 2D bar code, particularly preferably a data matrix code, for identifying on.
  • the code is applied to a non-opaque or transparent component.
  • the container and thereby the sample can be clearly identified and identified. This allows the container to be handled fully automatically and the sample of the container to be properly assigned. In addition, such a code allows anonymization of the container or the sample.
  • a code other than a 2D code may be used, such as a color code.
  • the fully opaque or opaque component includes or consists of polypropylene.
  • Polypropylene allows easy production of a fully opaque or opaque component. In addition, it allows the production in a 2 K injection molding process, together with the rest of the body.
  • the fully opaque or opaque component can also be made of another suitable material.
  • the lid and / or the body of the container is produced by an injection molding process, preferably a 2K injection molding process.
  • An injection molding process allows the parts of the container to be manufactured with consistent, high quality.
  • the parts can be produced with two plastic components in one manufacturing process.
  • the invention also relates to a method for filling a loading ⁇ pliers, preferably a container as described previously.
  • the method includes the steps:
  • the lid is further inserted into the body to place the lid in the second closed position.
  • the invention also relates to a method for transporting containers in a tube system with air flow. The method uses one of the containers described above.
  • FIG. 1 shows a lid of a vial according to the invention
  • FIG. 2 shows an external view of a vial according to the invention in the closed state
  • FIG. 3 shows an external view of a vial according to the invention in the open state
  • FIG. 1 shows a lid 3 of a vial 1 according to the invention (see FIG. 2 or 3).
  • the lid 3 is partially insertable into an open end of a body 2 (see Figure 2 or 3) and is formed of two components 3 ⁇ , 3 ⁇ ⁇ , which differ in their Shore hardness.
  • the lid 3 is with a 2 K
  • the shore-harder component 3 ⁇ is a polypropylene.
  • the shore-softer component 3 ⁇ ⁇ is a thermoplastic elastomer with a Shore hardness of 40 Shore A according to ISO 7619 measured.
  • the shore-softer component 3 ⁇ ⁇ is in a region of the lid 3, which can be introduced into the body 2, in the circumferential direction completely surrounded by the shore-harder component 3 ⁇ . In an upper end of the lid 3, however, the shore-softer component 3 ⁇ ⁇ runs radially outward.
  • the Shore-softer component 3 ⁇ ⁇ extends in the direction of the longitudinal axis of the vial 1 only over a partial distance of the shore harder component 3 ⁇ .
  • a towards the closed end zei ⁇ ing end of the lid 3 is formed only by the shore-harder compo ⁇ nent 3 ⁇ , which forms an additional, open on one side cavity.
  • the shore-softer component 3 ⁇ ⁇ allows a penetration of the lid with a cannula for sample filling and / or sampling. After removal of the cannula from the cover 3, closes the shore-softer component 3 ⁇ ⁇ the passage opening automatically ⁇ table.
  • the lid 3 has a lower region 5, which can be introduced into the body 2.
  • the lid 3 has an upper region 4 which has a larger radius than the lower region 5 and can not be introduced into the body 2.
  • the lower region has two grooves 6.
  • a sealing surface ei ⁇ ner lower groove 6 ⁇ is partially formed circumferentially.
  • a recess 7 interrupts the sealing surface of the lower groove 6 ⁇ .
  • a sealing surface of an upper groove 6 ⁇ ⁇ is formed completely circumferential.
  • FIG. 2 shows an external view of a vial 1 according to the invention with body 2 in the closed state.
  • the lid 3 is in the second closed position.
  • the body 2 is formed by two plastic components 2 ⁇ , 2 ⁇ ⁇ . Both components 2 ⁇ , 2 ⁇ ⁇ are polypropylene, wherein a component 2 ⁇ ⁇ is formed opaque.
  • the body 2 is again formed by a 2K injection molding process.
  • the opaque component 2 ⁇ ⁇ is disposed at a closed end of the body 2. At its surface facing away from the body 2, the opaque component has a data matrix code (not shown). The code is used to identify the vial. This allows the vial to be automatically assigned and edited.
  • the body 2 has a flange 10 (see Figure 3), which is formed by the non-opaque polypropylene component 2 ⁇ .
  • the flange 10 is formed flush with an outer diameter of the upper portion 4 of the lid and thereby ensures that two vials 1 with their lids 3 do not get caught. There are created by this training virtually no additional edges through the lid 3 or the body 2.
  • the outer wall runs in the opaque region 2 ⁇ ⁇ conical.
  • the area has a conicity of 10 °.
  • the upper section has a low taper of 2 °.
  • FIG. 3 shows an external view of a vial 1 according to the invention with body 2 in the open state.
  • a region near the open end of the body 2 has a counter rib 12 (see FIG. 5) which can interact with the grooves 6 ⁇ , 6 ⁇ ⁇ .
  • FIGS. 4a-c show a vial 1 according to the invention in different closure positions.
  • the lid 3 is not introduced into the body 2.
  • the vial 1 is in an open position.
  • the cover 3 is in the first shutter Stel ⁇ lung.
  • the cover 3 is partially inserted into the body 2 ⁇ .
  • the vial 1 can be filled. Gas that was in the vial can escape through the vent channel (indicated by dashed arrows). This prevents excessive overpressure inside the vial 1.
  • Figures 5a and 5b show a longitudinal section through a inventions dungsgmässes Vial 1 in a first and second closure Stel ⁇ lung.
  • FIG. 5b shows the cover 3 in the second closed position.
  • the upper groove 6 ⁇ ⁇ which has a circumferentially formed sealing surface, with the counter rib 12 in active ⁇ connection and seals the cavity of the vial 1 from the environment.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Closures For Containers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

L'invention concerne un récipient de réception (1) comprenant un corps (2) et un couvercle (3). Le corps (2) présente une extrémité ouverte et une extrémité fermée. Le couvercle (3) peut être inséré au moins en partie dans l'extrémité ouverte du corps (2) afin de fermer le corps (2). Le couvercle (3) comprend au moins un élément en plastique (3'') qui est conçu de façon à pouvoir être perforé par une canule et à être étanche aux fluides après le retrait de la canule. Le récipient (1) est conçu de façon à ce que le couvercle (3) puisse adopter au moins des première et seconde positions de fermeture. Dans la première position de fermeture, une cavité du corps peut être remplie à travers le couvercle (3) à l'aide d'une canule, et du gaz peut s'échapper de la cavité par l'intermédiaire d'au moins une voie de purge d'air. Dans la seconde position de fermeture, ladite voie de purge d'air est fermée.
EP17701478.4A 2017-01-24 2017-01-24 Récipient de réception, technique de remplissage d'un récipient de réception, procédé de transport de récipients de réception et utilisation d'un récipient de réception Withdrawn EP3573900A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2017/051441 WO2018137760A1 (fr) 2017-01-24 2017-01-24 Récipient de réception, technique de remplissage d'un récipient de réception, procédé de transport de récipients de réception et utilisation d'un récipient de réception

Publications (1)

Publication Number Publication Date
EP3573900A1 true EP3573900A1 (fr) 2019-12-04

Family

ID=57890815

Family Applications (1)

Application Number Title Priority Date Filing Date
EP17701478.4A Withdrawn EP3573900A1 (fr) 2017-01-24 2017-01-24 Récipient de réception, technique de remplissage d'un récipient de réception, procédé de transport de récipients de réception et utilisation d'un récipient de réception

Country Status (3)

Country Link
US (1) US20210331843A1 (fr)
EP (1) EP3573900A1 (fr)
WO (1) WO2018137760A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210131256A1 (en) * 2019-11-04 2021-05-06 Enercorp Sand Solutions Inc. Sand quantification skid

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901402A (en) * 1973-03-14 1975-08-26 Becton Dickinson Co Stopper-piston
FR2416848A1 (fr) * 1978-02-08 1979-09-07 Rumpler Jean Jacques Bouchon de recipient de produits medicamenteux
US4244478A (en) * 1979-06-27 1981-01-13 Mpl, Inc. Closure assembly for unit dose vial
AR231626A1 (es) * 1982-01-30 1985-01-31 Gesepa Patentverwertung Elemento de cierre para recipientes y procedimiento para su fabricacion
US5036992A (en) * 1990-03-27 1991-08-06 Mouchawar Marvin L Medicine vial cap for needleless syringe
US5203825A (en) 1991-06-07 1993-04-20 Becton, Dickinson And Company Capillary tube assembly including a vented cap
US5279606A (en) * 1991-08-28 1994-01-18 Habley Medical Technology Corporation Non-reactive composite sealing barrier
US5377854A (en) * 1993-04-16 1995-01-03 International Technidyne Corp. Stopper apparatus for a test tube or similar article
US5937616A (en) * 1998-04-22 1999-08-17 Ray; John D. Vial capping machine
US6604561B2 (en) * 2000-02-11 2003-08-12 Medical Instill Technologies, Inc. Medicament vial having a heat-sealable cap, and apparatus and method for filling the vial
FR2809710B1 (fr) * 2000-05-30 2002-12-13 Valois Sa Systeme d'obturation d'un reservoir d'un dispositif de distribution de produit lyophilise
ITFI20020246A1 (it) * 2002-12-13 2004-06-14 Molteni & C Contenitore sterile.
ES2261104B1 (es) * 2006-06-19 2007-06-16 Grifols, S.A. "tapon para frascos de productos esteriles y utilizacion de dicho tapon en la dosificacion esteril".
CN102740822A (zh) * 2010-02-01 2012-10-17 积水医疗株式会社 栓体及体液采集器具组

Also Published As

Publication number Publication date
WO2018137760A1 (fr) 2018-08-02
US20210331843A1 (en) 2021-10-28

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