EP3385174B1 - Dispositif d'emballage de portions de médicament - Google Patents

Dispositif d'emballage de portions de médicament Download PDF

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Publication number
EP3385174B1
EP3385174B1 EP17165405.6A EP17165405A EP3385174B1 EP 3385174 B1 EP3385174 B1 EP 3385174B1 EP 17165405 A EP17165405 A EP 17165405A EP 3385174 B1 EP3385174 B1 EP 3385174B1
Authority
EP
European Patent Office
Prior art keywords
packaging material
packaging
material web
joining
drug portions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP17165405.6A
Other languages
German (de)
English (en)
Other versions
EP3385174A1 (fr
Inventor
Dietmar Gross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson Rowa Germany GmbH
Original Assignee
Becton Dickinson Rowa Germany GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP17165405.6A priority Critical patent/EP3385174B1/fr
Application filed by Becton Dickinson Rowa Germany GmbH filed Critical Becton Dickinson Rowa Germany GmbH
Priority to DK17165405T priority patent/DK3385174T3/da
Priority to AU2018249339A priority patent/AU2018249339B2/en
Priority to PCT/EP2018/056274 priority patent/WO2018184795A1/fr
Priority to BR112019020156-4A priority patent/BR112019020156B1/pt
Priority to KR1020197029406A priority patent/KR102532860B1/ko
Priority to CN201880023514.5A priority patent/CN110536838A/zh
Priority to JP2019554983A priority patent/JP2020516546A/ja
Priority to CA3056480A priority patent/CA3056480A1/fr
Publication of EP3385174A1 publication Critical patent/EP3385174A1/fr
Application granted granted Critical
Publication of EP3385174B1 publication Critical patent/EP3385174B1/fr
Priority to JP2022189400A priority patent/JP7497412B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/101—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
    • B65B5/103—Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B51/00—Devices for, or methods of, sealing or securing package folds or closures; Devices for gathering or twisting wrappers, or necks of bags
    • B65B51/10—Applying or generating heat or pressure or combinations thereof
    • B65B51/26—Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
    • B65B61/04—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for severing webs, or for separating joined packages
    • B65B61/06—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for severing webs, or for separating joined packages by cutting
    • B65B61/10—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for severing webs, or for separating joined packages by cutting using heated wires or cutters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B9/00—Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
    • B65B9/10—Enclosing successive articles, or quantities of material, in preformed tubular webs, or in webs formed into tubes around filling nozzles, e.g. extruded tubular webs
    • B65B9/20—Enclosing successive articles, or quantities of material, in preformed tubular webs, or in webs formed into tubes around filling nozzles, e.g. extruded tubular webs the webs being formed into tubes in situ around the filling nozzles
    • B65B9/22—Forming shoulders; Tube formers
    • G—PHYSICS
    • G07—CHECKING-DEVICES
    • G07F—COIN-FREED OR LIKE APPARATUS
    • G07F17/00—Coin-freed apparatus for hiring articles; Coin-freed facilities or services
    • G07F17/0092—Coin-freed apparatus for hiring articles; Coin-freed facilities or services for assembling and dispensing of pharmaceutical articles

Definitions

  • the present invention relates to a device for packaging medicament portions and the use of individual components of the device.
  • Devices for packaging medicament portions are known, for example, from US Pat WO 2013/034504 A1 known.
  • the devices comprise, depending on the expansion stage, several hundred storage and dispensing stations, in each of which several drug portions of a particular type of drug are stored.
  • individual drug portions may be dispensed from the supply and dispensing stations, which are then fed via a guide means to a packaging device at which the drug portions are packaged.
  • the medicament portions stored in the storage and dispensing stations are compiled and blistered according to the individual patient's intake in accordance with the prescribed medication.
  • corresponding supply and dispensing stations for dispensing one or more medicament portions are activated by means of a control device of the device.
  • the actual delivery takes place by separating a medicament portion stored in a storage container with a separating device of the storage and dispensing station and transferring it via a dispensing opening to a guide device of the device for packaging medicament portions.
  • the guide device By means of the guide device, the medicament portion is fed, regularly with the interposition of a collecting device, to a packaging device which packages or fuses one or more medicament portions.
  • Modern blister machines regularly include a plurality of supply and dispensing stations and also a plurality of collection devices, in which compilations of optionally several drug portions are temporarily stored before they are handed over to the packaging device.
  • Modern blister machines are capable of packaging a large number of drug portion assortments per hour.
  • a packaging material web is converted from a packaging device into a blister tube having a multiplicity of blister bags arranged one behind the other.
  • the packaging device is supplied via a packaging material supply a flexible, elongated packaging material web. This is folded in the direction V-shaped and welded at predetermined intervals transversely to the direction, with a partially closed blister bag is formed, in which then the compilation is handed over to drug portions. Due to the pretreatment of the packaging material web, the actual receiving area has approximately the shape of an inverted hollow pyramid.
  • the partially closed blister bag is closed by welding in the direction of travel and another welding transversely to the direction of travel (which can also form the first transverse weld for the subsequent blister bag).
  • the device for packaging medicament portions according to Claim 1 comprises a plurality of supply and dispensing stations for dispensing individual medicament portions, at least one guiding and collecting arrangement for receiving and conveying the medicament portions dispensed from the supply and dispensing stations, and a packaging material supply for feeding a flexible, elongated packaging material web.
  • the device according to the invention further comprises a packaging device with a folding and guiding device, wherein the folding and guiding device has a packaging material receiving area with a through opening and is designed such that the elongated packaging material web is fed to the through opening, which in turn is designed such that the elongated packaging material web is formed in the running direction to a defined by the passage opening tubular packaging material web with a packaging material overlap region, and arranged above the folding and guide device guide with a receiving portion for drug portions and a guide portion extending in the direction of the passage opening of the folding and guiding device extends and drug delivery leads into the tubular packaging material web.
  • a first joining device arranged downstream of the folding and guiding device is provided in the device according to the invention, which joins the tubular packaging material web in the packaging material overlap region in the running direction of the tubular packaging material that a circumferentially closed hose is formed. Furthermore, a second joining device arranged downstream of the first joining device is provided, which connects the tubular one Packaging material web at predetermined intervals, based on the direction of travel, fauxhex, so that upwardly open bag-shaped receiving portions arise.
  • the second joining device is regularly designed such that the assembly of the packaging material web is performed approximately orthogonally or transversely to the direction of travel of the packaging material web, wherein the exact alignment of the joint depends on the shape of the blister bag to be achieved.
  • the packaging material web is formed into a differently shaped receiving region, namely an upwardly open bag-shaped receiving region, so that the risk of a jump-out of medicament portions is reduced solely due to the smaller number of open sides.
  • the direction of delivery of the medicament portions when transferring into the bag-shaped receiving area is different. Due to the configuration of the preformed partially closed blister bag, it was necessary in the prior art, the packaging material web obliquely, for example, to lead at a 45 ° angle, and then transfer the drug portions, for example, obliquely from above into the partially closed blister. Due to the design, the feeding direction of the medicament portions in the receiving area always deviated from the running direction of the packaging material web.
  • the second joining device is designed such that it is suitable for the high desired operating speeds. To periodically produce a joint substantially transverse to the direction of packaging material web can be stopped, for example, clocked; in the stop time, the packaging material web can then be joined together with suitable joining agents.
  • the packaging material web is not stopped periodically.
  • the joining device may, for example, comprise opposing rotating welding rolls with one or more welding means. At which distance then the joints are introduced, depends on several factors, namely the speed of the packaging material web, the rotational speed of the welding rollers and the number of welding agents per welding roller.
  • the second joining device comprises a drive device with which the second joining device is movable in and against the running direction of the tubular packaging material web.
  • the second joining device in the process of assembling the packaging material web, is carried along with it (transversely to the running direction) and, after assembly, is again moved counter to the running direction. Once all the drug portions to be introduced are supplied to the bag-shaped receiving portion, the process of assembly begins again; The length of the blister bag can thus be varied without changing the running speed of the packaging material web, that the time between the individual joining operations is varied.
  • blister tubes with a variety of Blister bags, each containing a collection of drug portions.
  • the blister tubes are usually stored outside the blister machine in roll form.
  • the blister packs of a blister hose do not virtually differ visually, so that a separation after removal from the blister machine is complicated.
  • the device for packaging medicament portions comprises a cutting device with a cutting means, with which the blister tube at predetermined intervals, based on the direction of travel, can be severed. How exactly the separation is carried out depends on the exact design of the blister hose. Usually, a transverse joint is part of two blister bags, ie the "lower” end of one and the “upper” end of another blister hose. A separation then takes place exactly at a joint; If each blister bag has two "own” joints, it can be separated between two joints.
  • the blister hose can already be severed during manufacture, a subsequent finding of the separation point is eliminated. Blister hoses of very different lengths can also be produced without problems with a corresponding device. It is even conceivable to separate the blister bags directly after production.
  • pre-separated Blister hoses include several blister packs, and these blister packs regularly affect several recipes, patients or intake times. Subsequent separation of the blister bag will therefore be necessary on a regular basis.
  • the cutting means comprises a plurality of incisors, and the blister tube and the cutting means are arranged to be movable relative to one another such that the blister tube is severable or pierceable.
  • the blister hose can therefore be provided with a component both severed and perforated.
  • patient-specific blister tubes can be produced, the individual blister bags can be easily solved and opened from each other due to the introduced between these perforation.
  • the way of distribution separation / perforation can be varied depending on the application.
  • the cutting device is structurally associated with the second joining device, so that the separation or perforation can be carried out particularly simply, since an exact detection of the point to be separated or perforated is not necessary, since the cutting means is carried along with the joining device ,
  • the second joining device comprises a joining means, in which the cutting means is accommodated, in such a way that the joining means extends in the running direction of the packaging material web downstream and upstream of the cutting means.
  • the invention further relates to a use of a packaging device with a folding and guiding device, which has a packaging material receiving area with a through opening and is designed such that an elongated packaging material web is fed to the through opening, which is designed such that the elongated packaging material web in the running direction to a tubular packaging material web defined by the through-opening is formed with a packaging material overlap region, a guide arranged above the folding and guiding device with a portion for drug portions and a guide portion which extends in the direction of the passage opening of the folding and guiding device and drug portions in the tubular
  • the packaging material web leads, a first joining device arranged downstream of the folding and guiding device, which assembles the tubular packaging material web in the packaging material overlap region in the running direction of the tubular packaging material, and a second joining device arranged downstream of the first joining device, which feeds the tubular packaging material web at predetermined intervals relative to the Running direction, fauxhegt, for producing a drug portions containing blister tube.
  • the invention relates to a use of a folding and guiding device for forming a moving in a direction of packaging material web for producing a drug portions containing Blisterschlauches, wherein the folding and guiding means comprises a packaging material receiving portion having a through hole and is formed such that an elongated packaging material web is supplied to the through hole, which is designed such that the elongated packaging material web is formed in the running direction to a defined by the passage opening tubular packaging material web with a packaging material overlap region.
  • FIG. 1 shows a schematic perspective view of an embodiment of the device according to the invention for the packaging of medicament portions, for the sake of clarity, a plurality of for the invention as such unessential components, such as cladding components, are omitted.
  • the apparatus 1 comprises a central frame comprising a plurality of vertical struts 2 (only one of which is visible), three horizontal struts 3a, 3b, 3c and a plurality of struts 4.
  • the lower horizontal strut 3c extends substantially the entire length of the struts Device, the upper horizontal struts 3a, 3b extend only in the "right" part of the device.
  • a guiding and collecting arrangement is arranged, which consists in the embodiment shown of a plurality of individual components.
  • the leadership and Collection arrangement comprises three axes 24a, 24b, 24c, which are received in corresponding holes of the horizontal struts 3a, 3b, 3c.
  • the axles 24a, 24b, 24c comprise one (24c), two (24b), or three (24a) pulleys 25, wherein between the pulleys 25 transport belts 22a, 22b, 22c are arranged.
  • the transport belts themselves are different in length according to the arrangement of the axes 24a, 24b, 24c on the different horizontal struts; the two upper conveyor belts are the same length and form a kind of composite, the lower conveyor belt is correspondingly longer and extends substantially over the entire length of the device.
  • This division into two parts is based on the fact that different components of the guiding and collecting arrangement are arranged on the transport belts 22a, 22b and the transport belt 22c.
  • elongated guide means 20 are arranged on holding means 23, while collecting means 21 are arranged on holding means 23 on the lower conveyor belt 22c, only a few of the guide means and the collecting means being shown for the purpose of illustration.
  • the device 1 comprises a drive 26 with which the axle 24a can be driven, whereby the transport belts 22a, 22b, 22c are moved via the deflection rollers. Since the transport belts 22a, 22b and the transport belt 22c are driven via the same axis 24a, they move at the same speed in the direction of rotation. With respect to the guide means and the collection means this means that they can be moved in the area between the axes 24a and 24b at the same speed and aligned with each other in the direction of rotation, so that for this path of the synchronous drug portions of a Guide device can be transferred to a guided under this collector.
  • the various drug portions are arranged in a plurality of supply and dispensing stations 10, of which in illustration 1 only a partial matrix is indicated.
  • These storage and dispensing stations 10 are attached to the device via components (not shown).
  • the storage and dispensing stations comprise a storage part, in which medicament portions are stored, and a dispensing part, via which individual medicament portions are transferred on request via a dispensing opening into a receiving opening of a guide device.
  • five horizontal rows of storage and dispensing stations are arranged, so that in this case the guide device comprises five receiving openings, via which medicament portions can be received.
  • the guide means are passed over the transport belts 22a, 22b to the supply and dispensing stations 10, and during this passage medicament portions can be dispensed from the supply and dispensing stations to the guide means, which align the drug portions with one below the guide means and in unison with this moving collecting device passes. Due to the construction of the device according to the invention, a guide device is thus guided past all the supply and delivery stations 10 of the device, so that each collection device can be supplied with each type of drug stored in the device during each run.
  • the device for packaging medicament portions comprises on the "left" side, on which the transport belts 22a, 22b do not extend, below the transport belt 22c, and thus below the collecting devices 21 fastened to the transport belt 22c, a packaging device 30 and a packaging material. feed 40.
  • About the packaging material supply 40 of the packaging means an elongated packaging material web 41 is supplied.
  • the packaging device 30 forms from the elongated packaging material web a blister tube 45 with a plurality of blister bags 44, wherein during this transformation medicament portions, which are temporarily stored in the collection devices 21, are transferred to the respective blister bags.
  • the formation of the blister bag and the transfer of the drug portions in the blister bag will be described with reference to the following figures.
  • the guiding and collecting arrangement is very complex, but allows a high blinding speed and access to a large number of types of drugs. But there are also much simpler management and collective arrangements conceivable.
  • the guiding and collecting arrangement may comprise only one (stationary) collecting device, to which all compositions of medicament portions are supplied. It is also conceivable that only a guide means is provided which can receive drug portions of all supply and dispensing stations.
  • FIG. 2 shows a schematic partial view of the packaging device in relation to a portion of the guiding and collecting arrangement.
  • the orientation of the packaging device 30 with respect to a portion of the guiding and collecting arrangement namely the orientation of a guide 60 of the packaging device 30 below the collecting means 21.
  • drug portions a dispensing flap 27 of the corresponding aligned collecting device opened and arranged in the collection drug portions fall by gravity in the guide 60, which feeds the actual Verblist für
  • FIGS. 3a-3d show different views of the packaging device.
  • the guiding device 60 which takes over assemblies of medicament portions from the collecting devices (not shown).
  • the guide 60 has a receiving portion 61 which is funnel-shaped.
  • the guide device 60 further comprises a guide section, which feeds drug portions into a receiving area of the packaging material web preformed to an open-top blister tube, the aforementioned process being described with reference to the following figures.
  • the folding and guiding device 50 which in particular below with reference to the FIGS. 5a-5c is described conically at the center and comprises a central passage opening 51, by means of which the supplied packaging material web is formed tubular. Roughly, the folding and guiding device has a crater-like configuration, wherein the packaging material web is fed via the outer flanks of the middle.
  • the packaging device comprises a first joining device 70 and a second joining device 90 for forming the blister bag having the separate blister bag, the first joining device 70 being located downstream of the guide 60 and the second joining device 90 downstream of the first joining device, with respect to the running direction of the packaging material web.
  • the packaging material web is preformed tube-shaped, but is still open to the circumference of the tube and downwards and upwards.
  • the first, arranged downstream of the guide joining device adds the packaging material web parallel to the direction, so that a closed tube is formed in FIG. 3a below the first joining device is indicated by reference numeral 42.
  • the second joining device 90 is arranged, by means of which the closed tube is joined transversely to the direction of rotation, it is thus produced with this joining means the bag shape as such.
  • the second joining device 90 is designed such that it can be moved with and against the running direction of the packaging material web.
  • the joining means 91a, 91b are moved together. Once the joining means have moved together, the joining device is moved downwards in the running direction, the duration of the merging being dependent on the time required for secure joining.
  • the joint is usually a weld, but other types of assembly are also conceivable.
  • the joining means are moved apart and moved the joining device as such again against the direction "up".
  • medicament portions can be supplied from above via the guide device to the receiving region just created. This receiving area is formed after insertion of the joint as open top bag.
  • the packaging material web is not stopped, but is moved further in the running direction, so that it continues to move downwards during the filling process.
  • the actual filling or the introduction of drug portions in the receiving portion so the open-top preformed blister, but clocked.
  • the joining means 91a, 91b of the second joining device are again brought together and the latter moved downwards with the packaging material web, whereby a further joint is introduced, which simultaneously produces the "upper” Joint of the blister bag just made and the "bottom” joint of the subsequently produced Blister bacterias is.
  • the packaging device is associated with a packaging material feed 40, via which the elongated packaging material web 41 of the folding and guiding device 50 is supplied (see in particular 3d figure ).
  • the packaging material feed 40 comprises a central packaging material roll 46 and various deflection rollers, which finally supply the elongate packaging material web 41 to the folding and guiding device 50.
  • two of the various pulleys are coupled to a drive 47.
  • the packaging material supply 40 is a central component of the packaging device; in other embodiments, the packaging material supply may be disposed outside of the actual packaging device to ensure a rapid change of the packaging material roll.
  • FIG. 4 shows a detailed view of the packaging device.
  • the second joining device 90 is associated with a drive unit 100 with which the part of the second joining device comprising the joining means 91a, 91b can be moved in and against the running direction of the packaging material web.
  • the first joining device 70 comprises two drive belts 74a, 74b, which encompasses a packaging material overlapping region 43, which is formed on account of the special configuration of the folding and guiding device. In this packaging material overlap region 43, the actual assembly of the packaging material takes place parallel to the running direction of the packaging material, wherein the components used for this purpose are described with reference to the following figures.
  • FIG. 4 Furthermore, a horizontal adjustment 92 assigned to the joining means 91b can be seen, with which the joining means can be moved in the X direction on the tubular packaging material web for introducing a joint and can be removed after introduction of the joint.
  • the second joining device can be moved in the Y direction in and against the running direction of the packaging material web.
  • FIG. 5 shows a perspective view of the first joining means 70 of the packaging device.
  • the first joining device comprises a receiving plate 71 on which the folding and joining device is arranged.
  • the first joining means comprises two drive belts 74a, 74b which engage around the packaging material overlap region.
  • the first joining device 70 comprises joining means 73a, 73b which rest against the packaging material for joining the latter; to better illustrate the individual components, the joining means in FIG. 5 spaced apart from each other.
  • the joining means 73a, 73b and the drive belts 74a, 74b are coupled to drives 72a-72c.
  • FIGS. 6a - 6b show two perspective views of the second joining device 90.
  • the second joining means 90 comprises two joining means 91a, 91b, which can be moved horizontally.
  • the second joining device comprises two horizontal displacements 92, 93, which can be moved separately from one another.
  • FIGS. 6a, 6b shown portion of the second joining device via a drive unit 100 in and against the direction of travel of the packaging material web movable.
  • FIG. 7 shows a detailed view of the packaging device, in the area of the introduction of the drug portions and the joining of the packaging material web.
  • FIG. 7 the course of the packaging material web can be seen through the first and second joining device.
  • the folding and guiding device 50 forms the packaging material web into a tubular packaging material web 42 having a packaging material overlap region 43 which is joined downstream of the folding and guiding device by means of the joining means 73a, 73b, wherein welding of the overlapping region occurs in the illustrated embodiment.
  • the second joining device 90 arranged downstream of the first joining device 70, the introduction of the horizontal joints takes place, with a weld also being introduced here in the embodiment shown.
  • the joining means 91a for this purpose comprises two welding edges 94a, 94b which press the packaging material web to be welded during the actual introduction of the welding against two opposing edges 95a, 95b of the joining means 91a.
  • the joining means 91a comprises a cutting means 111, which is embedded centrally in the joining means, such that the welding edges 94a, 94b are arranged downstream and upstream of the cutting means with respect to the running direction of the packaging material web.
  • FIGS. 8a-8c show further detail views of the packaging device, wherein a part of the components of the packaging device is omitted for better illustration.
  • FIG. 8a the course of the packaging material web with the overlap region 43 can be clearly seen.
  • the second joining device 90 is shown in the open position, and below the second joining device 90, the blister hose 45 is indicated as such; the exact guidance of the blister after making the individual blister bag is not shown.
  • FIG. 8b is omitted as the packaging material, and it is the guide portion 62 of the guide 60 can be seen, extending through the central through hole 51 of the folding and guiding device 50, which in FIG. 8c is illustrated extends.
  • the guide section 62 assists in the formation and shaping of the tubular packaging material web and delivers the medicament portions to the actual receiving region of the preformed packaging material web, which is located below the guide section 62. How exactly the medicament portions are introduced into the preformed packaging material web has already been described with reference to the preceding figures.
  • FIGS. 9a-9c show different views of the combination folding and guide device / guide.
  • FIG. 9a shows the aforementioned combination as it is installed in the packaging device.
  • the guide portion 62 of the guide 60 extends through a central through hole 51 of the folding and guiding device 50.
  • Bei FIG. 9b the guide 60 is displaced vertically with respect to the folding and guiding device 50 at FIG. 9c the two aforementioned components are shown separately from each other.
  • the shaping of the packaging material web takes place in that it runs up the flanks of the folding and guiding device towards the central passage opening and extends downwards into the latter.
  • the central through-opening 51 of the folding and guiding device 50 is not closed to the outside, but has a gap 53, this gap forming the packaging material overlapping area 43 during the formation of the packaging material web.
  • a corresponding overlapping region could also be provided by other embodiments of the central through-opening or the folding and guiding device.
  • FIG. 10a shows one Snapshot of the introduction of a joint transverse to the direction of the packaging material web.
  • the joining means 91a comprises a horizontal recess in which a cutting means 111 is arranged. Downstream and upstream of the cutting means, the joining means 91a comprises welding edges 94a, 94b which cooperate with counter edges 95a, 95b of the joining means 91b.
  • FIG. 10b 1 illustrates the cutting device 110, comprising a cutting means 111 having a plurality of cutting teeth 112. The cutting means 111 as such is directly connected to the horizontal adjustment 93 via a plurality of components.
  • the joining means 91a is connected via springs 96a, 96b with the aforementioned horizontal adjustment. Moving the horizontal adjustment thus moves both the joining means and the cutting means. However, as soon as the joining means 91a is moved over its welding edges to a stop which is regularly provided over the opposite edges 95a, 95b, a relative movement of the cutting means 111 to the joining means 91a takes place, by the joining means 91a via the joining means 91b, which with a horizontal adjustment 93 is coupled, is pressed in the springs 96a, 96b (see FIG. 10c ).
  • the cutting means 111 During the relative movement of the cutting means 111 to the joining means 91b, the cutting means emerges from the receptacle within the joining means 91a and penetrates into the packaging material web arranged between the joining means.
  • the packaging material web can be perforated or severed by means of the incisors. If there is only a slight relative movement, the perforation takes place; if the joining means 91a is pushed further into the springs 96a, 96b via the joining means 91b, the packaging material web is severed.

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Claims (12)

  1. Dispositif (1) d'emballage de portions de médicament, comportant
    une pluralité de postes de stockage et de distribution (10) pour distribuer des portions de médicament individuelles,
    au moins un système de guidage et de collecte pour recevoir les portions de médicament distribuées par les postes de stockage et de distribution (10) et le transfert des portions de médicament,
    un système d'alimentation en matériau d'emballage (40) pour alimenter une bande de matériau d'emballage longitudinale souple (41),
    un dispositif d'emballage (30) avec un dispositif de pliage et de guidage (50), sachant que le dispositif de pliage et de guidage (50) comporte un secteur de réception de matériau d'emballage (52) avec une ouverture de passage (51) et est constitué de telle manière que la bande de matériau d'emballage longitudinale (41) est acheminée vers l'ouverture de passage (51), laquelle est exécutée de telle sorte que la bande de matériau d'emballage longitudinale (41) est formée avec une zone de chevauchement de matériau d'emballage (43) dans le sens de la marche vers une bande de matériau d'emballage (42) en forme de flexible définie par l'ouverture de passage (51),
    un premier dispositif d'assemblage (70) disposé en aval du dispositif de pliage et de guidage (50), lequel rejoint la bande de matériau d'emballage (42) en forme de flexible au secteur de chevauchement de matériau d'emballage (43) dans le sens de la marche du matériau d'emballage en forme de flexible, ainsi
    qu'un deuxième dispositif d'assemblage (90) disposé en aval du premier dispositif d'assemblage (70), lequel rejoint la bande de matériau d'emballage (42) en forme de flexible à des intervalles prédéfinis par rapport au sens de la marche de telle sorte qu'il se forme un tube flexible d'emballage-coque transparent (45),
    caractérisé par un dispositif d'orientation (60) disposé au-dessus du dispositif de pliage et de guidage (50) avec une section de réception (61) pour les portions de médicament et une section de guidage (62) qui s'étend en direction de l'ouverture de passage (51) du dispositif de pliage et de guidage (50) et oriente les portions de médicament dans la bande de matériau d'emballage en forme de flexible (42) .
  2. Dispositif (1) d'emballage de portions de médicament selon la revendication 1,
    caractérisé en ce que
    le deuxième dispositif d'assemblage (90) comprend un dispositif d'entraînement (100) avec lequel le deuxième dispositif d'assemblage (90) peut être déplacé en direction de la marche et à l'opposé de celle-ci de la bande de matériau d'emballage en forme de flexible (42).
  3. Dispositif (1) d'emballage de portions de médicament selon la revendication 1 ou 2,
    caractérisé en ce que
    le dispositif (1) d'emballage de portions de médicament comprend un dispositif de découpe (110) avec un moyen de coupe (111) avec lequel le tube flexible d'emballage-coque transparent (45) peut être séparé à des intervalles prédéfinis, en se référant au sens de la marche.
  4. Dispositif (1) d'emballage de portions de médicament selon la revendication 3,
    caractérisé en ce que
    le moyen de coupe (111) comprend une pluralité de dents de coupe (112) et en ce que le tube flexible d'emballage-coque transparent (42) et le moyen de coupe (111) sont disposés pouvant se déplacer l'un par rapport à l'autre de telle manière que le tube flexible d'emballage-coque transparent (42) peut être séparé ou perforé.
  5. Dispositif (1) d'emballage de portions de médicament selon l'une quelconque des revendications 3 ou 4,
    caractérisé en ce que
    le dispositif de découpe (110) est attribué du point de vue construction au deuxième dispositif d'assemblage (90).
  6. Dispositif (1) d'emballage de portions de médicament selon l'une quelconque des revendications 3 - 5,
    caractérisé en ce que
    le deuxième dispositif d'assemblage (90) comprend un moyen d'assemblage (91a) dans lequel est logé le moyen de coupe (111).
  7. Utilisation d'un dispositif d'emballage (30) avec un dispositif de pliage et de guidage (50), sachant que le dispositif de pliage et de guidage (50) comporte un secteur de réception de matériau d'emballage (52) avec une ouverture de passage (51) et est constitué de telle manière que la bande de matériau d'emballage longitudinale (41) est acheminée vers l'ouverture de passage (51), laquelle est exécutée de telle sorte que la bande de matériau d'emballage longitudinale (41) est formée avec une zone de chevauchement de matériau d'emballage (43) dans le sens de la marche vers une bande de matériau d'emballage (42) en forme de flexible définie par l'ouverture de passage (51),
    un premier dispositif d'assemblage (70) disposé en aval du dispositif de pliage et de guidage (50), lequel rejoint la bande de matériau d'emballage (42) au secteur de chevauchement de matériau d'emballage (43) dans le sens de la marche du matériau d'emballage en forme de flexible, ainsi
    qu'un deuxième dispositif d'assemblage (90) disposé en aval du premier dispositif d'assemblage (70), lequel rejoint la bande de matériau d'emballage (42) en forme de flexible à des intervalles prédéfinis par rapport au sens de la marche,
    pour la fabrication d'un tube flexible d'emballage-coque transparent (45) comprenant des portions de médicament,
    caractérisé par
    un dispositif d'orientation (60) disposé au-dessus du dispositif de pliage et de guidage (50) avec une section de réception (61) pour les portions de médicament et une section de guidage (62) qui s'étend en direction de l'ouverture de passage (51) du dispositif de pliage et de guidage (50) et oriente les portions de médicament dans la bande de matériau d'emballage en forme de flexible (42).
  8. Utilisation d'un dispositif d'emballage (30) pour la fabrication d'un tube flexible d'emballage transparent (45) contenant des portions de médicament selon la revendication 7,
    caractérisé en ce que
    le deuxième dispositif d'assemblage (90) comprend un dispositif d'entraînement (100) avec lequel le deuxième dispositif d'assemblage (90) peut être déplacé en direction de la marche et à l'opposé de celle-ci de la bande de matériau d'emballage en forme de flexible (42).
  9. Utilisation d'un dispositif d'emballage (30) pour la fabrication d'un tube flexible d'emballage-coque transparent (45) contenant des portions de médicament selon la revendication 7 ou 8,
    caractérisé en ce que
    le dispositif (1) d'emballage des portions de médicament comprend un dispositif de découpe (110) avec un moyen de coupe (111) avec lequel le tube flexible d'emballage-coque transparent peut être séparé à des intervalles prédéfinis, en se référant au sens de la marche.
  10. Utilisation d'un dispositif d'emballage (30) pour la fabrication d'un tube flexible d'emballage-coque transparent (45) contenant des portions de médicament selon la revendication 9,
    caractérisé en ce que
    le moyen de coupe (111) comprend une pluralité de dents de coupe (112) et peut être déplacé de telle manière que le tube flexible d'emballage-coque transparent peut être séparé ou perforé.
  11. Utilisation d'un dispositif d'emballage (30) pour la fabrication d'un tube flexible d'emballage-coque transparent (45) contenant des portions de médicament selon la revendication 9 ou 10,
    caractérisé en ce que
    le dispositif de découpe (110) est attribué du point de vue construction au deuxième dispositif d'assemblage (90).
  12. Utilisation d'un dispositif d'emballage (30) pour la fabrication d'un tube flexible d'emballage-coque transparent (45) contenant des portions de médicament selon l'une quelconque des revendications 9 - 11,
    caractérisé en ce que le deuxième dispositif d'assemblage (90) comprend un moyen d'assemblage (91a) dans lequel le moyen de coupe (111) est logé.
EP17165405.6A 2017-04-07 2017-04-07 Dispositif d'emballage de portions de médicament Active EP3385174B1 (fr)

Priority Applications (10)

Application Number Priority Date Filing Date Title
DK17165405T DK3385174T3 (da) 2017-04-07 2017-04-07 Indretning til emballering af lægemiddelportioner
EP17165405.6A EP3385174B1 (fr) 2017-04-07 2017-04-07 Dispositif d'emballage de portions de médicament
PCT/EP2018/056274 WO2018184795A1 (fr) 2017-04-07 2018-03-13 Dispositif d'emballage de portions de médicaments
BR112019020156-4A BR112019020156B1 (pt) 2017-04-07 2018-03-13 Dispositivo para embalar porções de fármacos, uso de um dispositivo de embalagem e uso de um dispositivo de dobra e transporte
KR1020197029406A KR102532860B1 (ko) 2017-04-07 2018-03-13 약제 포장을 위한 장치
CN201880023514.5A CN110536838A (zh) 2017-04-07 2018-03-13 用于对药品份进行包装的设施
AU2018249339A AU2018249339B2 (en) 2017-04-07 2018-03-13 Device for packaging pharmaceutical portions
JP2019554983A JP2020516546A (ja) 2017-04-07 2018-03-13 薬剤ポーションを包装するためのデバイス
CA3056480A CA3056480A1 (fr) 2017-04-07 2018-03-13 Dispositif d'emballage de portions de medicaments
JP2022189400A JP7497412B2 (ja) 2017-04-07 2022-11-28 薬剤ポーションを包装するためのデバイス

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17165405.6A EP3385174B1 (fr) 2017-04-07 2017-04-07 Dispositif d'emballage de portions de médicament

Publications (2)

Publication Number Publication Date
EP3385174A1 EP3385174A1 (fr) 2018-10-10
EP3385174B1 true EP3385174B1 (fr) 2019-09-18

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ID=58501341

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Application Number Title Priority Date Filing Date
EP17165405.6A Active EP3385174B1 (fr) 2017-04-07 2017-04-07 Dispositif d'emballage de portions de médicament

Country Status (9)

Country Link
EP (1) EP3385174B1 (fr)
JP (2) JP2020516546A (fr)
KR (1) KR102532860B1 (fr)
CN (1) CN110536838A (fr)
AU (1) AU2018249339B2 (fr)
BR (1) BR112019020156B1 (fr)
CA (1) CA3056480A1 (fr)
DK (1) DK3385174T3 (fr)
WO (1) WO2018184795A1 (fr)

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Publication number Priority date Publication date Assignee Title
US11208223B2 (en) 2020-05-20 2021-12-28 Becton Dickinson Rowa Germany Gmbh Packaging apparatus for small piece goods and method for producing a blister tube comprising a plurality of blister bags
EP3912918A1 (fr) 2020-05-20 2021-11-24 Becton Dickinson Rowa Germany GmbH Dispositif d'emballage pour petites marchandises et procédé de fabrication d'un tube blister comprenant plusieurs sacs blister
EP3995401A1 (fr) 2020-11-09 2022-05-11 Becton Dickinson Rowa Germany GmbH Procédure et dispositif pour fabriquer un tube blister, et tube blister
US11673700B2 (en) 2021-06-22 2023-06-13 Vmi Holland B.V. Device and methods for packaging medicaments with fault detection
US11273103B1 (en) 2021-06-22 2022-03-15 Vmi Holland B.V. Method, computer program product and dispensing device for dispensing discrete medicaments
US11498761B1 (en) 2021-06-22 2022-11-15 Vmi Holland B.V. Method for dispensing discrete medicaments, a test station for testing a feeder unit, and a method for determining a fill level of a feeder unit

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Also Published As

Publication number Publication date
BR112019020156B1 (pt) 2023-10-10
CA3056480A1 (fr) 2018-10-11
BR112019020156A2 (pt) 2020-04-22
AU2018249339A1 (en) 2019-10-31
AU2018249339B2 (en) 2023-07-06
DK3385174T3 (da) 2019-10-28
KR102532860B1 (ko) 2023-05-15
WO2018184795A1 (fr) 2018-10-11
JP7497412B2 (ja) 2024-06-10
CN110536838A (zh) 2019-12-03
JP2020516546A (ja) 2020-06-11
EP3385174A1 (fr) 2018-10-10
JP2023025121A (ja) 2023-02-21
KR20190134644A (ko) 2019-12-04

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