EP2651368B1 - Dispositif pour remplir des capsules de produit de remplissage - Google Patents

Dispositif pour remplir des capsules de produit de remplissage Download PDF

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Publication number
EP2651368B1
EP2651368B1 EP20110778626 EP11778626A EP2651368B1 EP 2651368 B1 EP2651368 B1 EP 2651368B1 EP 20110778626 EP20110778626 EP 20110778626 EP 11778626 A EP11778626 A EP 11778626A EP 2651368 B1 EP2651368 B1 EP 2651368B1
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EP
European Patent Office
Prior art keywords
filling
capsule
station
capsule holder
row
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP20110778626
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German (de)
English (en)
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EP2651368A1 (fr
Inventor
Werner Runft
Jens Schlipf
Walter Boehringer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
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Robert Bosch GmbH
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Publication date
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Publication of EP2651368A1 publication Critical patent/EP2651368A1/fr
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Publication of EP2651368B1 publication Critical patent/EP2651368B1/fr
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations

Definitions

  • the present invention relates to a device for filling, in particular powdery, contents in capsules.
  • Capsules eg made of gelatin, which are produced from essentially cylindrical hollow shapes with hemispherical end regions are frequently used, in particular for medicaments.
  • One half of the capsules are filled with a medium, in particular a drug, and then the other half of the capsule is placed in order to obtain a closed capsule.
  • the filling of the capsule takes place here in filling machines, which in particular must ensure a high accuracy in the filling of the respective quantities in order to prevent incorrect dosages of a drug.
  • capsules often have longer filling times, which limits an output of a filling machine.
  • a device for metering and filling of powdery contents in containers in which two filling units are arranged side by side in series.
  • a partial filling by the first filling unit and a final final filling by the second filling unit can take place.
  • EP 1 413 434 A1 shows a device according to the preamble of claim 1.
  • the inventive device for filling of product in capsules with the features of claim 1 has the advantage over that in comparison with the known devices, an increase in performance by a improved filling of the capsules is achieved.
  • the device comprises a filling device for filling the capsules and a capsule holder, wherein the capsule holder at least one row of several receptacles, in which the capsules to be filled are arranged.
  • a station arrangement is provided with a plurality of stations, which are arranged one after the other.
  • a movement device which allows a relative filling movement between the filling device and the capsule holder at a capsule filling station, wherein the filling device occupies at least a first filling position for filling a first capsule and a second filling position for filling a second capsule relative to the capsule holder.
  • the filling device occupies at least a first filling position for filling a first capsule and a second filling position for filling a second capsule relative to the capsule holder.
  • the station arrangement comprises a station wheel with a plurality of capsule holders. This allows a very efficient flow during the filling process can be achieved.
  • the movement device performs a relative movement between the filling device and the capsule holder in the radial direction.
  • a relative movement in a first direction and a second direction in a horizontal plane is possible between the filling device and the capsule holder.
  • a plurality of parallel rows of capsules can be filled.
  • the first direction perpendicular to the second direction.
  • the filling station has a particularly compact design and it can be easily brought a sufficient amount of filling in the different filling positions.
  • the metering wheel has at least a first filling chamber and a second filling chamber and the metering rotates during a movement process from the first filling position to the second filling position to bring a filling chamber filled with filling material in the filling position and the empty filling chamber again fill. Due to the simultaneous movements of the dosing wheel and the capsule holder, capsule filling can be carried out in rapid succession both in the first filling position and in the second filling position.
  • a filling process of a capsule at the capsule filling station by means of the filling device is the shortest of all individual processes in the station arrangement.
  • a filling process in the capsule filling station takes half as long as the next shortest process in a station.
  • the capsule holder comprises a first series of receptacles and a second series of receptacles which are arranged parallel to one another.
  • a plurality of capsules can be arranged in a small area. More preferably, several more parallel rows, e.g. three or four or five rows.
  • the device further comprises a second capsule filling station with a second filling device.
  • a second capsule filling station with a second filling device.
  • the movement device is arranged on the filling device and the filling device is moved relative to the capsule holder. In this way, a high variability of the relative movement between the filling device and the capsule holder can be ensured.
  • the moving device comprises a driven cam or a linear motor or a servomotor.
  • a reliable movement of the moving device in the radial and vertical directions with short cycle times is possible.
  • an intermediate gear or as an intermediate member a carriage combined with a coupling or deflection can be provided to convert a generated vertical movement into a horizontal movement by means of deflection.
  • this can also be a screw (rack / pinion) can be used.
  • the drive can also be positioned below the machine level or base plate of the station.
  • the movement device is arranged on the capsule holder in order to move the capsule holder relative to the filling device.
  • the capsule holder has to be removed from the station wheel and has to be moved relative to the filling device.
  • the movement device comprises a guide element with curved path.
  • a slotted guide is further provided to bring the capsule holder in a first position and a second position.
  • a radial movement of the capsule holder during the downtime of the device is made possible.
  • the drive of the scenery can be done purely mechanically or via a cam mechanism by means of a linear or servo motor. For smaller outputs, the use of a pneumatic drive is also possible as an alternative.
  • the filling device preferably comprises a plurality of filling units, which are arranged in series, at the same time several To fill capsules in a row.
  • a number of filling units corresponds to a number of capsule receptacles in a row of the capsule holder.
  • the filling device is a pressure-vacuum filling device, wherein a filling amount is sucked by means of vacuum and discharged by means of pressure.
  • the filling device comprises a flexible product feed, which is provided between the reservoir and filling station.
  • a flexible product feed which is provided between the reservoir and filling station. This enables optimal product feeding to the moving filling station. For better cleaning and to prevent influences on the product properties, it is advantageous to produce the steel feeder and to make it pivotable. Between the reservoir or the filling station and the pivotable product supply each flexible seals are provided.
  • FIGS. 1 to 5 a device 20 for filling of powdery product 21 according to a first preferred embodiment described in detail.
  • FIG. 1 shows an overall view of the device 20, which includes a station wheel 40 with a total of twelve stations 1 to 12.
  • a total of twelve capsule holders 30 are arranged along the circumference, wherein each capsule holder 30 has a plurality of receptacles 31, 32 for receiving capsules 22.
  • the receptacles 31, 32 are arranged in each capsule holder 30 in two rows, namely a first row R1 and a second row R2 parallel to each other.
  • a rotational direction of the station wheel 40 is indicated by the arrow A.
  • the stations of the station wheel 40 are as follows. At station 1, empty, closed capsules, which comprise a capsule bottom part 23 and a capsule top part 24, are supplied from a supply. The capsules are introduced individually into a receptacle 31 of the capsule holder 30.
  • the capsules 22 are opened, that is, the capsule top 24 is removed from the capsule bottom 23 so that the capsule bottom 23 remains in the receptacle 31.
  • the feeding and opening of the capsules can also take place at the same station. Also, e.g. at station 1, the first row and at station 2, the second row are filled with capsules, and at the stations preferably also be opened the same.
  • the stations 3 and 4 are not occupied in this embodiment.
  • the station 5 is a filling station in which the opened capsules 22 are filled.
  • a filling device 25 is provided, which in detail in the Figures 2 and 3 is shown.
  • the filling device 25 comprises a metering wheel 26 and a storage hopper 27, in which the powdery filling material 21 is arranged.
  • the filling device 25 comprises a movement device, not visible here, which moves the filling device 25 in two directions, namely a first direction X and a second direction Y.
  • the two directions X, Y are perpendicular to each other (see. FIG. 1 ) and move the filling device 25 in a horizontal plane.
  • the movement device preferably comprises two separate drives which move the filling device 25 in the two directions X, Y.
  • FIG. 2 shows a start position of the filling, wherein the filling device 25 is disposed over a receptacle 31 of the first row R1 of the recordings and is thus positioned in a first filling position.
  • the metering wheel 26 has a first metering chamber 28a and a second metering chamber 28b. In the in FIG. 2 shown position is sucked at a receiving position E in the first metering chamber 28a by means of vacuum, a small filling amount 80. Thereafter, the metering wheel 26 rotates in the direction of arrow B by 180 ° and the small filling amount 80 at a discharge position F by means of compressed air, so that the filling amount 80 falls into the capsule base 23 into it. How out FIG.
  • the filling device 25 then performs a movement in the direction X, so that the dispensing position F is thus positioned in a second filling position on a receptacle 32 of the second row R2.
  • a second filling 51 is then filled in the same way in the capsule bottom 23 in the receptacle 32 of the second row R2.
  • the filling device 25 is moved in the direction Y and filled the capsule base 23 in the next shot. Then, the filler 25 can be moved again in the X direction to fill the next capsule bottom 23 in the first row R1.
  • the filling device can also be moved to a second filling position in the second direction Y after filling the capsule lower part 23 previously filled in the first row R1 in order to fill a further capsule bottom part 23 in the first row R1.
  • a movement in the second direction Y can also take place in order to fill a further capsule lower part 23 in the second row R2.
  • the metering wheel 26 may also have four metering chambers arranged at an angle of 90 ° to one another, wherein the metering wheel 26 is further rotated by 90 ° in each case for receiving and discharging the contents 21.
  • the filling device may also comprise a plurality of filling units in series, the number of filling units being equal to, or a multiple or a subset thereof, of the number of receptacles 31, 32 in the row R1 and R2.
  • a further filling device may also be provided at the station 6, so that, for example, the first filling device at the station 5 performs a partial filling and the second filling device 6 performs a final final filling and accurate metering of the filling quantity.
  • a weighing device may be provided to check the filled capsules.
  • the station 8 is an ejection station in which damaged or unfilled or incorrectly filled capsules can be discarded.
  • the capsule tops 24 are again positioned over the now filled capsule bottoms 23 and in the station 10, the capsules are closed again. This can be done for example by lowering the capsule caps on the capsule parts.
  • the station 11 is the dispensing station of the filled capsules and the station 12 is a cleaning station in which the capsule holders 30 are cleaned in order to avoid incorrect filling of the capsules into the receptacles 31.
  • FIG. 4 shows a arranged on the filling device 25 moving device 50, which performs a relative movement between the filling device 25 and the capsule holder 30 in the X direction.
  • the moving device 50 in this case comprises a carriage 53 which is fixed at one end to the filling device 25 and is slidably supported or stored in a holding device 55 by means of a bearing 54.
  • the opposite end of the carriage 53 is rotatably mounted on a cam 51, which is driven by a drive 52, for. B. a servomotor, is moved in the direction of arrow K and thus moves the carriage 53 together with the filling device 25 in the X direction.
  • the filling device 25 also has a flexible product supply 200, which is tubular and is arranged between a reservoir 210 and the storage hopper 27 pivotally. As a result, an optimal supply of the filling material 21 from the storage container 210 to the moving filling station 25 is achieved.
  • a movement device 60 can also be provided, from which a cam 61 together with drive 62 is arranged below a base plate 67 of the station 5.
  • the Moving device 60 has a mounted on the base plate 67 holding device 68, in which a first carriage 63 is slidably supported by a first bearing 64.
  • One end of the carriage 63 is rotatably connected to the cam 61, which is driven by a drive 62, preferably a form of a servomotor.
  • the opposite end of the first carriage 63 is connected via a deflection 65 with a second carriage 66 which is displaceably mounted in the holding device 68 by means of a second bearing 67.
  • FIG. 5 As can be seen, in this case a substantially vertical movement of the first carriage 63 in a direction S in a movement in the direction X is generated, which causes the displacement of the filling device 25 from the first row R1 to the second row R2 of the capsule holder 30.
  • a drive for the movement of the filling device 25 in the Y direction is in the FIGS. 4 and 5 not shown for simplicity of illustration, wherein the drive in the Y direction may be the same as that in the X direction. Alternatively, a linear drive can be provided.
  • FIGS. 6 to 9 a device 20 for filling of powdery product according to a second preferred embodiment described in detail.
  • the same or functionally identical components are designated here by the same reference numerals as in the first embodiment.
  • the device 20 in this second embodiment comprises a movement device 70 which is arranged on the station wheel 40 and a relative movement between the filling device 25 and the capsule holder 30 in FIG radial direction or X-direction performs.
  • the movement device 70 has a guide element 71 with a curved path 72.
  • a slotted guide 73 with a recess 74 formed therein (see FIG. FIG. 8 ) intended.
  • a holder 75 is attached (see FIG. FIG. 6 ), by means of which a capsule holder 30 is fixed to the movement device 70 via a rod 76 fixed in the holder 75.
  • the capsule holder 30 is moved in the radial direction or X-direction relative to the filling device 25, not shown here, in accordance with the shape of the curved path 72.
  • the slide guide 73 is located in an in FIG. 6 and FIG. 8 each represented by an arrow first position B, so that a row R1 of capsule holder 30 located in the capsule base 23 (see FIG. FIG. 6 ) can be filled.
  • the slide guide 73 is displaced from the first position B into a second position C represented by an arrow when the station wheel 40 is at a standstill FIG. 9 is illustrated.
  • a filling of capsule parts 23 in a second row R2 of a capsule holder 30 'positioned in this way can then take place (see FIG. FIG. 7 ).
  • both the filling device and the capsule holder can be moved.
  • a faster positioning of the capsule holder used and the filling station is possible, whereby a further increase in machine efficiency can be achieved in an individual application.
  • this also increases the machine outlay.
  • the filling device 25 has a filling time which is half a time of a station having the second shortest processing time. This makes it possible to comply with a given clock of the station wheel 40 very well, in particular, when using a filling device with five filling units, both the first row R1 and the second row R2 of the capsule holder 30 can be filled in only one station.
  • the device according to the invention for filling contents 21 into capsules 22 is preferably used for filling capsules with medicaments.

Claims (14)

  1. Dispositif pour remplir des capsules (22) de produit de remplissage (21), comprenant :
    - un dispositif de remplissage (25) pour acheminer du produit de remplissage (21) aux capsules (22),
    - un support de capsules (30) comprenant au moins une rangée de logements (31), dans lesquels sont disposées les capsules (22) à remplir,
    - un agencement de postes comprenant plusieurs postes qui sont disposés les uns après les autres, l'agencement de postes comprenant au moins un poste de remplissage de capsules (5) et un entraînement fonctionnant de manière cadencée, et
    - un dispositif de déplacement (50 ; 60 ; 70) qui effectue, au niveau d'un poste de remplissage de capsules (5), un mouvement relatif entre le dispositif de remplissage (25) et le support de capsules (30),
    - le dispositif de remplissage (25) adoptant, par rapport au support de capsules (30), au moins une première position de remplissage pour remplir une première capsule et une deuxième position de remplissage pour remplir une deuxième capsule,
    caractérisé en ce que le poste de remplissage de capsules (5) présente une roue de dosage (26) et une trémie de réserve (27) pour recevoir le produit de remplissage (21).
  2. Dispositif selon la revendication 1, caractérisé en ce que l'agencement de postes comprend une roue de postes (40) avec une pluralité de supports de capsules (30) et le dispositif de déplacement (50 ; 60 ; 70) effectue un mouvement relatif entre le dispositif de remplissage (25) et le support de capsules (30) dans la direction radiale (X).
  3. Dispositif selon l'une quelconque des revendications précédentes, caractérisé en ce qu'un mouvement relatif entre le dispositif de remplissage (25) et le support de capsules (30) est possible dans une première direction (X) et une deuxième direction (Y) dans un plan horizontal, la première direction (X) étant perpendiculaire à la deuxième direction (Y).
  4. Dispositif selon la revendication 1, caractérisé en ce que la roue de dosage (26) présente au moins une première chambre de remplissage (28a) et une deuxième chambre de remplissage (28b) et la roue de dosage (26) tourne pendant une opération de déplacement de la première position de remplissage à la deuxième position de remplissage, afin de remplir l'une des chambres de remplissage (28a, 28b) avec du produit de remplissage.
  5. Dispositif selon l'une quelconque des revendications précédentes, caractérisé en ce qu'un temps de remplissage dans le poste de remplissage de capsules (5) est le temps d'opération le plus court pour toutes les opérations individuelles des postes respectifs de l'agencement de postes.
  6. Dispositif selon l'une quelconque des revendications précédentes, caractérisé en ce que le support de capsules (30) comprend une première rangée (R1) de logements (31) et une deuxième rangée (R2) de logements (31), la première et la deuxième rangée étant disposées parallèlement l'une à l'autre.
  7. Dispositif selon l'une quelconque des revendications précédentes, caractérisé par un deuxième poste de remplissage de capsules (5) avec un deuxième dispositif de remplissage.
  8. Dispositif selon l'une quelconque des revendications précédentes, caractérisé en ce que le dispositif de déplacement (50 ; 60) est disposé au niveau du dispositif de remplissage (25) et déplace le dispositif de remplissage (25) par rapport au support de capsules (30).
  9. Dispositif selon la revendication 8, caractérisé en ce que le dispositif de déplacement (50, 60) comprend une came entraînée (50) ou un moteur linéaire ou un servomoteur.
  10. Dispositif selon l'une quelconque des revendications 1 à 7, caractérisé en ce que le dispositif de déplacement (70) est disposé sur le support de capsules (30) et déplace le support de capsules (30) par rapport au dispositif de remplissage (25).
  11. Dispositif selon la revendication 10, caractérisé en ce que le dispositif de déplacement (70) comprend un élément de guidage (71) avec une piste de came (72).
  12. Dispositif selon la revendication 11, comprenant en outre un guide à coulisse (73) afin d'amener le support de capsules (30) dans une première position (B) et dans une deuxième position (C).
  13. Dispositif selon l'une quelconque des revendications précédentes, caractérisé en ce que le dispositif de remplissage (25) comprend plusieurs unités de remplissage afin de remplir simultanément plusieurs capsules dans les logements (31) d'une rangée (R1, R2), le nombre des unités de remplissage correspondant notamment au nombre des logements (31) dans une rangée et le dispositif de remplissage étant notamment un dispositif de remplissage à pression de vide.
  14. Dispositif selon l'une quelconque des revendications précédentes, caractérisé en ce que le dispositif de remplissage (25) comprend une alimentation flexible en produit (200).
EP20110778626 2010-12-15 2011-11-04 Dispositif pour remplir des capsules de produit de remplissage Active EP2651368B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102010063138 2010-12-15
DE102011084555A DE102011084555A1 (de) 2010-12-15 2011-10-14 Vorrichtung zum Abfüllen von Füllgut in Kapseln
PCT/EP2011/069395 WO2012079840A1 (fr) 2010-12-15 2011-11-04 Dispositif pour remplir des capsules de produit de remplissage

Publications (2)

Publication Number Publication Date
EP2651368A1 EP2651368A1 (fr) 2013-10-23
EP2651368B1 true EP2651368B1 (fr) 2015-04-29

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Application Number Title Priority Date Filing Date
EP20110778626 Active EP2651368B1 (fr) 2010-12-15 2011-11-04 Dispositif pour remplir des capsules de produit de remplissage

Country Status (7)

Country Link
US (1) US9549876B2 (fr)
EP (1) EP2651368B1 (fr)
JP (1) JP5774123B2 (fr)
KR (1) KR101843717B1 (fr)
CN (1) CN103260581B (fr)
DE (1) DE102011084555A1 (fr)
WO (1) WO2012079840A1 (fr)

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DE102013113446B4 (de) 2013-12-04 2017-04-13 Fette Engineering GmbH Vorrichtung und Verfahren zum Befüllen von Kapseln
DE102015206407A1 (de) * 2015-04-10 2016-10-13 Robert Bosch Gmbh Vorrichtung zum Dosieren von pulverförmigem Füllgut
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JP5227708B2 (ja) 2008-09-18 2013-07-03 株式会社ミューチュアル 粉粒体の分配装置および分配方法
IT1390803B1 (it) * 2008-09-30 2011-10-19 Mg2 Srl Apparecchiatura per la dosatura di materiali pulverulenti o granulari in capsule o similari
IT1397691B1 (it) * 2009-12-22 2013-01-24 Mg 2 Srl Macchina rotativa intermittente per il riempimento di capsule con prodotti farmaceutici.

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JP5774123B2 (ja) 2015-09-02
CN103260581B (zh) 2015-08-26
US9549876B2 (en) 2017-01-24
EP2651368A1 (fr) 2013-10-23
CN103260581A (zh) 2013-08-21
US20130255833A1 (en) 2013-10-03
KR20130140076A (ko) 2013-12-23
KR101843717B1 (ko) 2018-03-30
DE102011084555A1 (de) 2012-06-21
WO2012079840A1 (fr) 2012-06-21
JP2014501673A (ja) 2014-01-23

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