EP2651368A1 - Dispositif pour remplir des capsules de produit de remplissage - Google Patents

Dispositif pour remplir des capsules de produit de remplissage

Info

Publication number
EP2651368A1
EP2651368A1 EP11778626.9A EP11778626A EP2651368A1 EP 2651368 A1 EP2651368 A1 EP 2651368A1 EP 11778626 A EP11778626 A EP 11778626A EP 2651368 A1 EP2651368 A1 EP 2651368A1
Authority
EP
European Patent Office
Prior art keywords
filling
capsule
station
capsule holder
movement
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP11778626.9A
Other languages
German (de)
English (en)
Other versions
EP2651368B1 (fr
Inventor
Werner Runft
Jens Schlipf
Walter Boehringer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
Original Assignee
Robert Bosch GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Bosch GmbH filed Critical Robert Bosch GmbH
Publication of EP2651368A1 publication Critical patent/EP2651368A1/fr
Application granted granted Critical
Publication of EP2651368B1 publication Critical patent/EP2651368B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations

Definitions

  • the present invention relates to a device for filling, in particular powdery, contents in capsules.
  • capsules e.g. made of gelatin, which are made of substantially cylindrical molds with hemispherical end portions.
  • One half of the capsules are filled with a medium, in particular a drug, and then the other half of the capsule is placed in order to obtain a closed capsule.
  • the filling of the capsule takes place here in filling machines, which in particular must ensure a high accuracy in the filling of the respective quantities in order to prevent incorrect dosages of a drug.
  • capsules often have longer filling times, which limits an output of a filling machine. From DE 199 15 259 A1, for example, a device for dosing and filling of
  • a partial filling by the first filling unit and a final final filling by the second filling unit can take place.
  • the device according to the invention for filling contents in capsules with the features of claim 1 has the advantage over that in comparison with the known devices an increase in performance is achieved by an improved filling of the capsules.
  • the device comprises a filling device for filling the capsules and a capsule holder, wherein the capsule holder at least one row of several receptacles, in which the capsules to be filled are arranged.
  • a station arrangement is provided with a plurality of stations, which are arranged one after the other.
  • Movement device which allows a relative filling movement between the filling device and the capsule holder at a capsule filling station, wherein the filling device relative to the capsule holder at least a first
  • Filling device and the capsule holder all capsules in the capsules are filled by taking several filling positions.
  • the filling device can fill the capsules located in the capsule holder both in the first and the second filling position.
  • the device is also characterized in particular by a very low structural complexity.
  • the station arrangement comprises a station wheel with a plurality of capsule holders. This allows a very efficient flow during the filling process can be achieved.
  • the movement device performs a relative movement between the filling device and the capsule holder in the radial direction.
  • a relative movement in a first direction and a second direction in a horizontal plane is possible between the filling device and the capsule holder.
  • Rows of capsules to be filled is the first direction perpendicular to the second direction.
  • the filling station preferably has a metering wheel and a storage hopper for receiving the contents.
  • a reliable operation of the filling material can be achieved in the metering without great structural complexity.
  • the filling station has a particularly compact design and it can be easily brought a sufficient amount of filling in the different filling positions.
  • the metering wheel has at least a first filling chamber and a second filling chamber and the metering wheel rotates during a movement process of the first
  • capsule filling can be carried out in rapid succession both in the first filling position and in the second filling position.
  • a filling process in the capsule filling station takes half as long as the next shortest process in a station.
  • the capsule holder comprises a first series of receptacles and a second series of receptacles which are arranged parallel to one another.
  • a plurality of capsules can be arranged in a small area. More preferably, several more parallel rows, e.g. three or four or five rows.
  • the device further comprises a second capsule filling station with a second filling device.
  • a second capsule filling station with a second filling device.
  • Moving device disposed on the filling device and the filling device is moved relative to the capsule holder.
  • the moving device comprises a driven one
  • Cam or a linear motor or a servomotor As a result, a reliable movement of the moving device in the radial and vertical directions with short cycle times is possible.
  • an intermediate gear or as an intermediate member a carriage combined with a coupling or deflection can be provided to convert a generated vertical movement into a horizontal movement by means of deflection.
  • this can also be a screw (rack / pinion) can be used.
  • the drive can also be positioned below the machine level or base plate of the station.
  • the movement device is arranged on the capsule holder in order to move the capsule holder relative to the filling device.
  • the capsule holder has to be removed from the station wheel and has to be moved relative to the filling device.
  • the movement device comprises a guide element with curved path.
  • a slotted guide is further provided to bring the capsule holder in a first position and a second position.
  • a radial movement of the capsule holder during the downtime of the device is made possible.
  • the filling device preferably comprises a plurality of filling units, which are arranged in series, at the same time several To fill capsules in a row.
  • a number of the filling units corresponds to a number of capsule receptacles in a row of the
  • the filling device is a pressure-vacuum filling device, wherein a filling amount is sucked by means of vacuum and discharged by means of pressure.
  • the filling device comprises a flexible product feed, which is provided between the reservoir and filling station.
  • a flexible product feed which is provided between the reservoir and filling station. This enables optimal product feeding to the moving filling station. For better cleaning and to prevent influences on the product properties, it is advantageous to produce the steel feeder and to make it pivotable. Between the reservoir or the filling station and the pivotable product supply are each flexible seals
  • FIG. 1 shows a schematic top view of a device for filling filling material according to a first exemplary embodiment of the invention
  • FIG. 2 shows a schematic sectional view through a filling device of FIG. 1 in a first position
  • FIG. 3 shows a schematic sectional view through a filling device of FIG. 1 in a second position
  • FIG. 4 shows a schematic sectional view of a movement device for the filling device of FIGS. 2 and 3
  • Figure 5 is a schematic sectional view of an alternative
  • FIG. 6 shows a perspective view of a second embodiment of a movement device including slide guide in a first position
  • Figure 7 is a perspective view of the movement device of
  • FIG. 6 in a second position
  • Figure 8 is an enlarged view of the slotted guide in the first
  • Figure 9 is an enlarged view of the slotted guide in the second
  • Figure 1 shows an overall view of the device 20, which includes a station wheel 40 with a total of twelve stations 1 to 12.
  • a total of twelve capsule holders 30 are arranged along the circumference, wherein each capsule holder 30 has a plurality of receptacles 31, 32 for receiving capsules 22.
  • the receptacles 31, 32 are arranged in each capsule holder 30 in two rows, namely a first row R1 and a second row R2 parallel to each other.
  • a rotational direction of the station wheel 40 is indicated by the arrow A.
  • the stations of the station wheel 40 are as follows. At the station 1 are empty, closed capsules, which a capsule base 23 and a
  • Capsule top 24 include, supplied from a supply.
  • the capsules are introduced individually into a receptacle 31 of the capsule holder 30.
  • the capsules 22 are opened, ie, the capsule upper part 24 is removed from the capsule lower part 23, so that the capsule lower part 23 remains in the receptacle 31.
  • the feeding and opening of the capsules can also take place at the same station. Also, e.g. at station 1 the first row and at station 2 the second row are filled up with capsules, and at the
  • Stations preferably also be opened the same.
  • the stations 3 and 4 are not occupied in this embodiment.
  • the station 5 is a filling station in which the opened capsules 22 are filled.
  • a filling device 25 is provided, which is shown in detail in Figures 2 and 3.
  • the filling device 25 comprises a metering wheel 26 and a storage hopper 27, in which the powdery filling material 21 is arranged.
  • the filling device 25 comprises a movement device, not visible here, which moves the filling device 25 in two directions, namely a first direction X and a second direction Y.
  • the two directions X, Y are perpendicular to each other (see Figure 1) and move the filling device 25 in a horizontal plane.
  • the movement device preferably comprises two separate drives which move the filling device 25 in the two directions X, Y.
  • the metering wheel 26 has a first metering chamber 28a and a second
  • Dosing chamber 28b on.
  • a small filling quantity 50 is sucked into the first metering chamber 28a at a receiving position E by means of a vacuum.
  • the metering wheel 26 rotates in the direction of arrow B by 180 ° and the small filling amount 50 at a discharge position F by means of compressed air, so that the filling amount 50 falls into the capsule base 23 inside.
  • the filling device 25 then moves in the direction X, so that the dispensing position F is thus in a second position
  • Filling position is positioned over a receptacle 32 of the second row R2.
  • a second filling 51 is then in the same way in the capsule base 23 in the
  • the filling device 25 is moved in the direction Y and filled the capsule base 23 in the next shot. Then, the filler 25 can be moved again in the X direction to fill the next capsule bottom 23 in the first row R1. Alternatively, the filling device can also be moved to a second filling position in the second direction Y after filling the capsule lower part 23 previously filled in the first row R1 with another one
  • Capsule bottom 23 in the first row R1 to fill.
  • a movement in the second direction Y can also take place in order to fill a further capsule lower part 23 in the second row R2.
  • the metering wheel 26 may also have four metering chambers arranged at an angle of 90 ° to one another, wherein the metering wheel 26 is further rotated by 90 ° in each case for receiving and discharging the contents 21.
  • the filling device may also comprise a plurality of filling units in series, the number of filling units being equal to, or a multiple or a subset thereof, of the number of receptacles 31, 32 in the row R1 and R2.
  • a further filling device may also be provided at the station 6, so that, for example, the first filling device at the station 5 performs a partial filling and the second filling device 6 performs a final final filling and accurate metering of the filling quantity.
  • a weighing device may be provided to check the filled capsules.
  • the station 8 is an ejection station in which damaged or unfilled or incorrectly filled capsules can be discarded.
  • the capsule tops 24 are again positioned over the now filled capsule bottoms 23 and in the station 10, the capsules are closed again. This can be done for example by lowering the capsule caps on the capsule parts.
  • the station 11 is the dispensing station of the filled capsules and the station 12 is a cleaning station in which the capsule holders 30 are cleaned in order to avoid incorrect filling of the capsules into the receptacles 31.
  • FIG. 4 shows a movement device 50 arranged on the filling device 25, which moves relative to a relative position between the filling device 25 and the filling device 25
  • Capsule holder 30 executes in the X direction.
  • the movement device 50 here comprises a carriage 53, which is fastened at one end to the filling device 25 and in a holding device 55 by means of a
  • Support 54 is slidably supported or stored.
  • the opposite end of the carriage 53 is rotatably mounted on a cam 51, which is driven by a drive 52, for. B. a servomotor, is moved in the direction of arrow K and thus moves the carriage 53 together with the filling device 25 in the X direction.
  • the filling device 25 is displaced from the position shown in FIG. 4 above the first row R1 into the position above the second row R2 of the capsule holder 30.
  • a subsequent movement of the driven cam disk 51 results in a corresponding movement in the reverse X direction.
  • Embodiment arranged substantially in a common plane.
  • the filling device 25 also has a flexible product feed 200, which is of tubular design and is arranged pivotably between a storage container 210 and the storage hopper 27. As a result, an optimal supply of the filling material 21 from the
  • Reservoir 210 reaches the moving filling station 25.
  • a moving device 60 may be provided, of which a cam 61 together with drive 62 below a base plate 67 of the station 5 is arranged.
  • the Moving device 60 has mounted on the base plate 67
  • Holding device 68 in which a first carriage 63 is slidably supported by a first bearing 64. One end of the carriage 63 is rotatably connected to the cam 61, which is driven by a drive 62,
  • a servomotor preferably form a servomotor, is driven.
  • first carriage 63 is connected via a deflection 65 with a second carriage 66 which is displaceably mounted in the holding device 68 by means of a second bearing 67.
  • second carriage 66 which is displaceably mounted in the holding device 68 by means of a second bearing 67.
  • this is a substantially vertical one
  • a drive for the movement of the filling device 25 in the Y-direction is not shown in FIGS. 4 and 5 for the sake of simplicity of illustration, the drive being in Y-direction.
  • a linear drive can be provided.
  • Capsule holder 30 allows. Furthermore, this ensures rapid filling of the capsules with significantly shorter cycle times. In addition, a flexible adaptation or integration of the movement device 50, 60 corresponding to the respective space conditions on the station wheel 40 of the device 20 according to the invention is possible.
  • the device 20 in this second embodiment comprises a
  • Moving device 70 which is arranged on the station wheel 40 and a
  • the movement device 70 has a guide element 71 with a curved path 72. Furthermore, a sliding guide 73 with a recess 74 formed therein (see FIG. 8) is provided on the guide element 71. A holder 75 is fastened in the recess 74 (see FIG. 6), by means of which a capsule holder 30 is fastened to the movement device 70 via a rod 76 fixed in the holder 75.
  • the capsule holder 30 is rotated in the radial direction or X-axis in accordance with the shape of the curved path 72.
  • the slotted guide 73 is in this case in a first position B represented in each case by an arrow in FIG. 6 and FIG. 8, so that a row R1 can be filled by capsule parts 23 located in the capsule holder 30 (see FIG.
  • the slide guide 73 is displaced from the first position B into a second position C represented by an arrow when the station wheel 40 is at a standstill, which is illustrated in FIG.
  • the filling device 25 has a filling time which is half a time of a station having the second shortest processing time. This makes it possible to have a
  • both the first row R1 and the second row R2 of the capsule holder 30 can be filled in only one station.
  • the device according to the invention for filling contents 21 into capsules 22 is preferably used for filling capsules with medicaments.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Basic Packing Technique (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne un dispositif pour remplir des capsules (22) de produit de remplissage (21), comprenant un dispositif de remplissage (25) pour amener le produit de remplissage (21) vers les capsules (22), un dispositif de support de capsules (30) comprenant au moins une rangée de logements (31) dans lesquels les capsules (22) à remplir sont disposées, un ensemble de stations comprenant plusieurs stations qui sont disposées les unes à côté des autres, l'ensemble de stations comprenant au moins une station de remplissage (5) et un entraînement fonctionnant de manière cadencée, et un dispositif de déplacement qui effectue dans la station de remplissage de capsule (5) un déplacement relatif entre le dispositif de remplissage (25) et le dispositif de support de capsule (30), le dispositif de remplissage (25) prenant par rapport au dispositif de support de capsules (30) au moins une première position de remplissage pour remplir une première capsule et une deuxième position de remplissage pour remplir une deuxième capsule.
EP20110778626 2010-12-15 2011-11-04 Dispositif pour remplir des capsules de produit de remplissage Active EP2651368B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102010063138 2010-12-15
DE102011084555A DE102011084555A1 (de) 2010-12-15 2011-10-14 Vorrichtung zum Abfüllen von Füllgut in Kapseln
PCT/EP2011/069395 WO2012079840A1 (fr) 2010-12-15 2011-11-04 Dispositif pour remplir des capsules de produit de remplissage

Publications (2)

Publication Number Publication Date
EP2651368A1 true EP2651368A1 (fr) 2013-10-23
EP2651368B1 EP2651368B1 (fr) 2015-04-29

Family

ID=44906149

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20110778626 Active EP2651368B1 (fr) 2010-12-15 2011-11-04 Dispositif pour remplir des capsules de produit de remplissage

Country Status (7)

Country Link
US (1) US9549876B2 (fr)
EP (1) EP2651368B1 (fr)
JP (1) JP5774123B2 (fr)
KR (1) KR101843717B1 (fr)
CN (1) CN103260581B (fr)
DE (1) DE102011084555A1 (fr)
WO (1) WO2012079840A1 (fr)

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IT1392277B1 (it) * 2008-12-18 2012-02-24 Ima Spa Macchina e metodo per riempire e controllare capsule
DE102011085283A1 (de) * 2011-02-21 2012-08-23 Robert Bosch Gmbh Vorrichtung zum Dosieren von pulverförmigem Füllgut
DE102013109471B8 (de) * 2013-08-30 2015-02-19 Fette Engineering GmbH Vorrichtung zum Befüllen und Verschließen von Kapseln
DE102013113446B4 (de) 2013-12-04 2017-04-13 Fette Engineering GmbH Vorrichtung und Verfahren zum Befüllen von Kapseln
DE102015206407A1 (de) * 2015-04-10 2016-10-13 Robert Bosch Gmbh Vorrichtung zum Dosieren von pulverförmigem Füllgut
DE102017204083A1 (de) * 2017-03-13 2018-09-13 Robert Bosch Gmbh Vorrichtung zum Abfüllen von Füllgut
EP3578157A1 (fr) * 2018-06-05 2019-12-11 Harro Höfliger Verpackungsmaschinen GmbH Machine de remplissage de capsule destiné à remplir des capsules et unité de nettoyage destinée à être à l'utilisation dans une machine de remplissage de capsules
EP3608233B1 (fr) * 2018-08-08 2020-10-21 Harro Höfliger Verpackungsmaschinen GmbH Cylindre doseur
IT201900013971A1 (it) * 2019-08-05 2021-02-05 Ima Spa Macchina per la realizzazione di capsule.
KR102333883B1 (ko) * 2021-07-14 2021-12-03 주식회사 피티케이 캡슐 충진기용 원료 공급 장치
CN115352690A (zh) * 2022-08-06 2022-11-18 扬州中惠制药有限公司 一种制药生产用的胶囊生产设备

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Also Published As

Publication number Publication date
US9549876B2 (en) 2017-01-24
CN103260581A (zh) 2013-08-21
KR101843717B1 (ko) 2018-03-30
JP2014501673A (ja) 2014-01-23
WO2012079840A1 (fr) 2012-06-21
EP2651368B1 (fr) 2015-04-29
JP5774123B2 (ja) 2015-09-02
KR20130140076A (ko) 2013-12-23
CN103260581B (zh) 2015-08-26
DE102011084555A1 (de) 2012-06-21
US20130255833A1 (en) 2013-10-03

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