EP2393028A3 - Medikamentenauswahlverfahren - Google Patents
Medikamentenauswahlverfahren Download PDFInfo
- Publication number
- EP2393028A3 EP2393028A3 EP20110001368 EP11001368A EP2393028A3 EP 2393028 A3 EP2393028 A3 EP 2393028A3 EP 20110001368 EP20110001368 EP 20110001368 EP 11001368 A EP11001368 A EP 11001368A EP 2393028 A3 EP2393028 A3 EP 2393028A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- selecting
- genotype
- patient
- genes encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
- G16B50/10—Ontologies; Annotations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
- G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Public Health (AREA)
- Databases & Information Systems (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Bioethics (AREA)
- Primary Health Care (AREA)
- Medicinal Chemistry (AREA)
- Data Mining & Analysis (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Business, Economics & Management (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44854703P | 2003-02-20 | 2003-02-20 | |
| EP04713404.4A EP1599576B1 (de) | 2003-02-20 | 2004-02-20 | Verfahren zur auswahl von antidepressiva-medikationen |
Related Parent Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP04713404.4 Division | 2004-02-20 | ||
| EP04713404.4A Division-Into EP1599576B1 (de) | 2003-02-20 | 2004-02-20 | Verfahren zur auswahl von antidepressiva-medikationen |
| EP04713404.4A Division EP1599576B1 (de) | 2003-02-20 | 2004-02-20 | Verfahren zur auswahl von antidepressiva-medikationen |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP2393028A2 EP2393028A2 (de) | 2011-12-07 |
| EP2393028A3 true EP2393028A3 (de) | 2012-02-29 |
| EP2393028B1 EP2393028B1 (de) | 2015-09-30 |
Family
ID=32908604
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP04713404.4A Expired - Lifetime EP1599576B1 (de) | 2003-02-20 | 2004-02-20 | Verfahren zur auswahl von antidepressiva-medikationen |
| EP11001368.7A Expired - Lifetime EP2393028B1 (de) | 2003-02-20 | 2004-02-20 | Verfahren zur Auswahl von Antidepressiva-Medikationen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP04713404.4A Expired - Lifetime EP1599576B1 (de) | 2003-02-20 | 2004-02-20 | Verfahren zur auswahl von antidepressiva-medikationen |
Country Status (6)
| Country | Link |
|---|---|
| US (6) | US8401801B2 (de) |
| EP (2) | EP1599576B1 (de) |
| JP (3) | JP5348840B2 (de) |
| DK (2) | DK1599576T3 (de) |
| ES (2) | ES2557885T3 (de) |
| WO (1) | WO2004074456A2 (de) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8401801B2 (en) | 2003-02-20 | 2013-03-19 | Mayo Foundation For Medical Education And Research | Methods for selecting medications |
| US8688385B2 (en) * | 2003-02-20 | 2014-04-01 | Mayo Foundation For Medical Education And Research | Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype |
| CA3113166A1 (en) | 2004-09-30 | 2006-04-13 | Vanda Pharmaceuticals Inc. | Methods for the administration of iloperidone |
| EP3223182A1 (de) * | 2005-11-29 | 2017-09-27 | Children's Hospital Medical Center | Optimierung und individualisierung von medikamentenauswahl und -dosierung |
| EP1976426A4 (de) * | 2006-01-19 | 2011-01-19 | Samuel R Valenti | Medizinisches diagnosesystem und verfahren |
| WO2007133506A2 (en) * | 2006-05-09 | 2007-11-22 | University Of Louisville Research Foundation , Inc. | Personalized medicine management software |
| WO2008052167A2 (en) * | 2006-10-27 | 2008-05-02 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Methods to identify patients at risk of developing adverse events during treatment with antidepressant medication |
| WO2008076434A2 (en) * | 2006-12-18 | 2008-06-26 | Theragenetics | Predicting a response to risperidone |
| US8099298B2 (en) | 2007-02-14 | 2012-01-17 | Genelex, Inc | Genetic data analysis and database tools |
| US7795033B2 (en) * | 2007-03-19 | 2010-09-14 | The United States Of America As Represented By The Department Of Health And Human Services | Methods to predict the outcome of treatment with antidepressant medication |
| JP2011501276A (ja) * | 2007-10-12 | 2011-01-06 | ペイシェンツライクミー, インコーポレイテッド | 健康関連の転帰を予測するためのオンラインコミュニティを使用した自己改善方法 |
| US8688416B2 (en) * | 2008-10-20 | 2014-04-01 | Michael Fearon | Methods and systems for improved pharmaceutical intervention in coagulation control |
| US8315815B2 (en) | 2008-12-30 | 2012-11-20 | The Invention Science Fund I, Llc | Computational methods and systems for suggesting modulators of CYP450 as treatment options |
| US8073633B2 (en) * | 2008-12-30 | 2011-12-06 | The Invention Science Fund I, Llc | Computational methods and systems for suggesting modulators of CYP450 as treatment options |
| US8321151B2 (en) | 2008-12-30 | 2012-11-27 | The Invention Science Fund I, Llc | Computational methods and systems for treatment in relation to modulation of CYP450 enzyme activity |
| WO2010090203A1 (ja) | 2009-02-04 | 2010-08-12 | 株式会社トクヤマ | 多結晶シリコンの製造法 |
| CA2758481C (en) | 2009-04-30 | 2018-03-20 | Patientslikeme, Inc. | Systems and methods for encouragement of data submission in online communities |
| US9558320B2 (en) * | 2009-10-26 | 2017-01-31 | Genomas, Inc. | Physiogenomic method for predicting drug metabolism reserve for antidepressants and stimulants |
| JP5672705B2 (ja) * | 2010-01-26 | 2015-02-18 | 住友化学株式会社 | 発光装置およびその製造方法 |
| US10435746B2 (en) | 2010-10-21 | 2019-10-08 | Mayo Foundation For Medical Education And Research | Methods for selecting medications for treating patients having attention-deficit hyperactivity disorder |
| CN110838348A (zh) * | 2010-11-01 | 2020-02-25 | 皇家飞利浦电子股份有限公司 | 包括专有测试的特许使用费的自动化代理的体外诊断测试 |
| US20120209081A1 (en) * | 2011-02-11 | 2012-08-16 | Abbas Sadeghian | Method of preventing patient injury |
| US9235686B2 (en) | 2012-01-06 | 2016-01-12 | Molecular Health Gmbh | Systems and methods for using adverse event data to predict potential side effects |
| WO2014055398A1 (en) | 2012-10-05 | 2014-04-10 | Siemens Healthcare Diagnostics Inc. | Method for detecting an increased risk or incidence of colorectal cancer |
| US10210312B2 (en) | 2013-02-03 | 2019-02-19 | Youscript Inc. | Systems and methods for quantification and presentation of medical risk arising from unknown factors |
| US20140243211A1 (en) | 2013-02-28 | 2014-08-28 | Indiana University Research & Technology Corporation | Blood biomarkers for suicidality |
| US20170253928A1 (en) * | 2013-03-15 | 2017-09-07 | Pathway Genomics Corporation | Method and system to predict response to treatments for mental disorders |
| US20140274764A1 (en) * | 2013-03-15 | 2014-09-18 | Pathway Genomics Corporation | Method and system to predict response to treatments for mental disorders |
| US20190055603A1 (en) * | 2015-04-28 | 2019-02-21 | Proove Biosciences, Inc. | System and method for processing genotype information relating to drug metabolism |
| WO2016176482A1 (en) * | 2015-04-28 | 2016-11-03 | Proove Biosciences, Inc. | System and method for processing genotype information relating to non-opioid response |
| US10395759B2 (en) | 2015-05-18 | 2019-08-27 | Regeneron Pharmaceuticals, Inc. | Methods and systems for copy number variant detection |
| CN108291259A (zh) | 2015-06-12 | 2018-07-17 | 印第安纳大学研究与技术公司 | 使用组合的基因组和临床风险评估预测自杀倾向 |
| US12071669B2 (en) | 2016-02-12 | 2024-08-27 | Regeneron Pharmaceuticals, Inc. | Methods and systems for detection of abnormal karyotypes |
| EP3635130A4 (de) | 2017-05-12 | 2021-06-09 | Indiana University Research and Technology Corporation | Präzisionsmedikament zur behandlung und prävention von suizidalität |
| CN120636518A (zh) | 2017-05-12 | 2025-09-12 | 密歇根大学董事会 | 个体和队列药理学表型预测平台 |
| US12417825B2 (en) | 2017-09-15 | 2025-09-16 | Alden Scientific, Inc. | Systems and methods for collecting and analyzing comprehensive medical information |
| WO2019083024A1 (ja) * | 2017-10-27 | 2019-05-02 | シスメックス株式会社 | 遺伝子解析方法、遺伝子解析装置、管理サーバ、遺伝子解析システム、プログラム、および記録媒体 |
| JP7320345B2 (ja) * | 2017-10-27 | 2023-08-03 | シスメックス株式会社 | 遺伝子解析方法、遺伝子解析装置、遺伝子解析システム、プログラム、および記録媒体 |
| US10950354B1 (en) * | 2018-03-02 | 2021-03-16 | Allscripts Software, Llc | Computing system for pharmacogenomics |
| US11894139B1 (en) | 2018-12-03 | 2024-02-06 | Patientslikeme Llc | Disease spectrum classification |
| US11965206B2 (en) | 2018-12-21 | 2024-04-23 | John Stoddard | Method of dosing a patient with multiple drugs using adjusted phenotypes of CYP450 enzymes |
| AU2020326626A1 (en) * | 2019-08-02 | 2022-03-10 | Tempus Ai, Inc. | Data-based mental disorder research and treatment systems and methods |
| CN110643689A (zh) * | 2019-10-29 | 2020-01-03 | 陕西佰美基因股份有限公司 | 一种检测HTR2A基因rs6313位点的TaqMan探针实时荧光PCR方法及其引物探针组合 |
| EP4329759A4 (de) | 2021-04-30 | 2025-07-16 | Mind Medicine Inc | Lsd-salzkristallformen |
| EP4387624A4 (de) | 2021-08-19 | 2025-07-30 | Mind Medicine Inc | Formulierungen von d-lysrgsäurediethylester mit sofortiger freisetzung für therapeutische anwendungen |
| AR132917A1 (es) | 2023-03-22 | 2025-08-13 | Neomente Corp | Método para la selección de fármacos neuropsiquiátricos para el tratamiento de la depresión |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002012434A2 (en) * | 2000-08-10 | 2002-02-14 | Glaxo Group Limited | A global electronic medicine response profile testing network |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5252743A (en) | 1989-11-13 | 1993-10-12 | Affymax Technologies N.V. | Spatially-addressable immobilization of anti-ligands on surfaces |
| US5833599A (en) | 1993-12-13 | 1998-11-10 | Multum Information Services | Providing patient-specific drug information |
| DE19782097T1 (de) | 1996-11-06 | 1999-10-14 | Sequenom Inc | Zusammensetzungen und Verfahren zur Immobilisierung von Nucleinsäuren an feste Träger |
| US20020010595A1 (en) | 1998-02-27 | 2002-01-24 | Kapp Thomas L. | Web-based medication management system |
| CN1304512A (zh) * | 1998-04-03 | 2001-07-18 | 三角药品公司 | 为疗法选择提供指导的系统、方法和计算机程序产品 |
| US6183963B1 (en) | 1998-10-23 | 2001-02-06 | Signalgene | Detection of CYP1A1, CYP3A4, CYP2D6 and NAT2 variants by PCR-allele-specific oligonucleotide (ASO) assay |
| WO2000050639A2 (en) * | 1999-02-22 | 2000-08-31 | Variagenics, Inc. | Gene sequence variations with utility in determining the treatment of disease |
| US20010034023A1 (en) * | 1999-04-26 | 2001-10-25 | Stanton Vincent P. | Gene sequence variations with utility in determining the treatment of disease, in genes relating to drug processing |
| US6297014B1 (en) * | 1999-07-02 | 2001-10-02 | Cedars-Sinai Medical Center | Genetic test to determine non-responsiveness to statin drug treatment |
| AU2001231091A1 (en) * | 2000-01-21 | 2001-07-31 | Vincent P. Stanton Jr. | Identification of genetic components of drug response |
| JP2001256305A (ja) * | 2000-03-13 | 2001-09-21 | Kazutoshi Mogi | 遺伝子検査データ活用方法 |
| WO2001079540A2 (en) * | 2000-04-18 | 2001-10-25 | Virco Bvba | Methods for measuring drug resistance |
| US20020010552A1 (en) * | 2000-05-26 | 2002-01-24 | Hugh Rienhoff | System for genetically characterizing an individual for evaluation using genetic and phenotypic variation over a wide area network |
| US20020076774A1 (en) | 2000-06-21 | 2002-06-20 | Chunhua Yan | Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof |
| JP2002024385A (ja) | 2000-06-30 | 2002-01-25 | Coreflow Technologies:Kk | 遺伝子情報管理システム及びその管理方法 |
| US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| JPWO2002025519A1 (ja) * | 2000-09-20 | 2004-01-29 | 株式会社東芝 | 遺伝子による診療情報提供方法、診療情報提供端末及び診療情報受給端末 |
| WO2002025528A1 (en) | 2000-09-21 | 2002-03-28 | Theradoc.Com, Inc. | Systems and methods for manipulating medical data via a decision support system |
| US6450956B1 (en) | 2000-11-06 | 2002-09-17 | Siemens Corporate Research, Inc. | System and method for treatment and outcome measurement analysis |
| JP2002197189A (ja) | 2000-12-26 | 2002-07-12 | Sanyo Electric Co Ltd | 薬品テーラーメイドシステム |
| JP2002245171A (ja) | 2001-02-13 | 2002-08-30 | Canon Sales Co Inc | 医療情報管理装置、その方法、プログラム、記憶媒体 |
| US20030170176A1 (en) | 2001-03-14 | 2003-09-11 | Mcgill University | Individualization of therapy with antipsychotics |
| JP2002318858A (ja) * | 2001-04-19 | 2002-10-31 | Toshitada Kameda | 医療計画作成支援システム及びコンピュータプログラム |
| US20020187483A1 (en) * | 2001-04-20 | 2002-12-12 | Cerner Corporation | Computer system for providing information about the risk of an atypical clinical event based upon genetic information |
| WO2003008637A2 (en) | 2001-07-17 | 2003-01-30 | Xanthus Life Sciences, Inc. | Use of genotyping in the individualization of therapy |
| US7529685B2 (en) * | 2001-08-28 | 2009-05-05 | Md Datacor, Inc. | System, method, and apparatus for storing, retrieving, and integrating clinical, diagnostic, genomic, and therapeutic data |
| US7461006B2 (en) | 2001-08-29 | 2008-12-02 | Victor Gogolak | Method and system for the analysis and association of patient-specific and population-based genomic data with drug safety adverse event data |
| US20030105596A1 (en) | 2001-10-29 | 2003-06-05 | Goldstein David Benjamin | Methods for evaluating responses of a group of test subjects to a drug or other clinical treatment and for predicting responses in other subjects |
| US20030108938A1 (en) * | 2001-11-06 | 2003-06-12 | David Pickar | Pharmacogenomics-based clinical trial design recommendation and management system and method |
| US20030157110A1 (en) | 2002-01-07 | 2003-08-21 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of metabolic disorders, including obesity and diabetes |
| US7274707B2 (en) | 2002-03-07 | 2007-09-25 | Koninklijke Philips Electronics N. V. | Coexistence of stations capable of different modulation schemes in a wireless local area network |
| US20030204415A1 (en) * | 2002-04-30 | 2003-10-30 | Calvin Knowlton | Medical data and medication selection and distribution system |
| US7809585B1 (en) | 2002-06-12 | 2010-10-05 | Anvita, Inc. | System and method for patient-specific optimization of medical therapy by simultaneous symbolic reasoning in all clinical dimensions |
| US8688385B2 (en) | 2003-02-20 | 2014-04-01 | Mayo Foundation For Medical Education And Research | Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype |
| US8401801B2 (en) | 2003-02-20 | 2013-03-19 | Mayo Foundation For Medical Education And Research | Methods for selecting medications |
| US20040193446A1 (en) | 2003-03-27 | 2004-09-30 | Mayer Steven Lloyd | System and method for managing a patient treatment program including a prescribed drug regimen |
| US20050069936A1 (en) | 2003-09-26 | 2005-03-31 | Cornelius Diamond | Diagnostic markers of depression treatment and methods of use thereof |
| WO2005038049A2 (en) | 2003-10-06 | 2005-04-28 | Heinrich Guenther | System and method for optimizing drug therapy |
| US7813880B2 (en) | 2004-03-25 | 2010-10-12 | University Of Maryland, Baltimore | Apparatus and method for providing optimal concentrations for medication infusions |
| AU2005241496A1 (en) | 2004-05-03 | 2005-11-17 | Cygene Laboratories, Inc. | Method and system for a comprehensive knowledge-based anonymous testing and reporting, and providing selective access to test results and report |
| US20050260549A1 (en) | 2004-05-19 | 2005-11-24 | Feierstein Roslyn E | Method of analyzing question responses to select among defined possibilities and means of accomplishing same |
| US7546285B1 (en) | 2004-09-24 | 2009-06-09 | Sprint Communications Company L.P. | System and method for scoring development concepts |
| KR101178463B1 (ko) | 2004-12-21 | 2012-09-07 | 아카데미아 시니카 | 와파린의 감도를 예측하는 유전적 변이체 |
| WO2006075254A2 (en) | 2005-01-13 | 2006-07-20 | Progenika Biopharma, S.A. | Methods and products for in vitro genotyping |
| US20060280786A1 (en) | 2005-06-14 | 2006-12-14 | Rabinow Barrett E | Pharmaceutical formulations for minimizing drug-drug interactions |
| FR2887663A1 (fr) | 2005-06-24 | 2006-12-29 | Ippm Holding Sa | Procede et systeme d'information pour generer des donnees d'optimisation d'un traitement medical, et equipement mis en oeuvre dans ce systeme |
| EP3223182A1 (de) | 2005-11-29 | 2017-09-27 | Children's Hospital Medical Center | Optimierung und individualisierung von medikamentenauswahl und -dosierung |
| US20140046696A1 (en) * | 2012-08-10 | 2014-02-13 | Assurerx Health, Inc. | Systems and Methods for Pharmacogenomic Decision Support in Psychiatry |
-
2004
- 2004-02-20 US US10/545,931 patent/US8401801B2/en active Active
- 2004-02-20 ES ES11001368.7T patent/ES2557885T3/es not_active Expired - Lifetime
- 2004-02-20 JP JP2006503753A patent/JP5348840B2/ja not_active Expired - Lifetime
- 2004-02-20 WO PCT/US2004/005113 patent/WO2004074456A2/en not_active Ceased
- 2004-02-20 DK DK04713404.4T patent/DK1599576T3/en active
- 2004-02-20 EP EP04713404.4A patent/EP1599576B1/de not_active Expired - Lifetime
- 2004-02-20 DK DK11001368.7T patent/DK2393028T3/en active
- 2004-02-20 EP EP11001368.7A patent/EP2393028B1/de not_active Expired - Lifetime
- 2004-02-20 ES ES04713404.4T patent/ES2575903T3/es not_active Expired - Lifetime
-
2010
- 2010-01-13 JP JP2010004875A patent/JP5438524B2/ja not_active Expired - Lifetime
- 2010-07-08 JP JP2010155468A patent/JP5438610B2/ja not_active Expired - Lifetime
-
2013
- 2013-03-11 US US13/792,365 patent/US20130311202A1/en not_active Abandoned
-
2015
- 2015-01-30 US US14/610,941 patent/US9111028B2/en not_active Expired - Lifetime
- 2015-11-13 US US14/940,375 patent/US20160237494A1/en not_active Abandoned
-
2019
- 2019-05-15 US US16/413,125 patent/US20200048712A1/en not_active Abandoned
-
2023
- 2023-02-01 US US18/104,717 patent/US20230420139A1/en not_active Abandoned
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002012434A2 (en) * | 2000-08-10 | 2002-02-14 | Glaxo Group Limited | A global electronic medicine response profile testing network |
Non-Patent Citations (1)
| Title |
|---|
| EVANS WILLIAM E ET AL: "Pharmacogenomics: Translating functional genomics into rational therapeutics", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, WASHINGTON, DC; US, vol. 286, no. 5439, 15 October 1999 (1999-10-15), pages 487 - 491, XP002193947, ISSN: 0036-8075, DOI: 10.1126/SCIENCE.286.5439.487 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20150148336A1 (en) | 2015-05-28 |
| US9111028B2 (en) | 2015-08-18 |
| WO2004074456A2 (en) | 2004-09-02 |
| EP1599576A4 (de) | 2008-02-13 |
| ES2557885T3 (es) | 2016-01-29 |
| JP2010273681A (ja) | 2010-12-09 |
| US20130311202A1 (en) | 2013-11-21 |
| EP2393028A2 (de) | 2011-12-07 |
| US20070003931A1 (en) | 2007-01-04 |
| EP1599576B1 (de) | 2016-04-27 |
| DK1599576T3 (en) | 2016-08-01 |
| JP2007525154A (ja) | 2007-09-06 |
| US8401801B2 (en) | 2013-03-19 |
| HK1164503A1 (en) | 2012-09-21 |
| JP5348840B2 (ja) | 2013-11-20 |
| EP1599576A2 (de) | 2005-11-30 |
| US20230420139A1 (en) | 2023-12-28 |
| JP5438610B2 (ja) | 2014-03-12 |
| JP5438524B2 (ja) | 2014-03-12 |
| EP2393028B1 (de) | 2015-09-30 |
| JP2010176661A (ja) | 2010-08-12 |
| WO2004074456A3 (en) | 2006-07-27 |
| US20200048712A1 (en) | 2020-02-13 |
| DK2393028T3 (en) | 2016-01-11 |
| US20160237494A1 (en) | 2016-08-18 |
| ES2575903T3 (es) | 2016-07-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2393028A3 (de) | Medikamentenauswahlverfahren | |
| WO2008017038A3 (en) | Methods for selecting medications | |
| WO2005112886A3 (en) | Methods and articles for the delivery of therapeutic agents | |
| WO2008118258A3 (en) | Genemap of the human genes associated with adhd | |
| WO2002040717A3 (en) | In vitro cell-based methods for biological validation and pharmacological screening of chemical entities and biologicals | |
| WO2001035316A3 (en) | Computationally derived protein structures in pharmacogenomics | |
| EP2392660A3 (de) | ENA-Nukleinsäurearzneimittel, die das Splicing im mRNA-Vorläufer verändern | |
| WO2005047904A3 (en) | High-density amine-functionalized surface | |
| CA2179012A1 (en) | Molecular diagnosis of familial adenomatous polyposis | |
| WO2008112177A8 (en) | Genemap of the human genes associated with schizophrenia | |
| WO2008067195A3 (en) | Genemap of the human genes associated with crohn's disease | |
| AU2003267581A1 (en) | Drug delivery | |
| WO2002066684A3 (en) | Genome-based personalized medicine | |
| WO2004083385A3 (en) | Quorum sensing signaling in bacteria | |
| WO2007025085A8 (en) | Genemap of the human genes associated with crohn's disease | |
| AU2003266291A1 (en) | Single nucleotide polymorphisms predicting adverse drug reactions and drug efficacy in cardiovascular disease | |
| WO2002072604A3 (en) | Genes and polymorphisms associated with cardiovascular disease and their use | |
| EP2249155A3 (de) | Krebsmarker | |
| WO2003016563A3 (fr) | Cible moleculaire de la neurotoxicite | |
| EP1948831A4 (de) | Alzheimer-assoziierte genetische polymorphismen, nachweisverfahren dafür und verwendung davon | |
| WO2008123901A3 (en) | Genemap of the human genes associated with endometriosis | |
| WO2004035819A8 (en) | Oligonucleotide analogues for detecting and analyzing nucleic acids | |
| WO2005052180A3 (en) | Ntrk1 genetic markers associated with progression of alzheimer’s disease | |
| AU2003276727A1 (en) | Method of haplotype-based genetic analysis for determining risk for developing insulin resistance, coronary artery disease and other phenotypes | |
| EP2354228A3 (de) | Auf interferontherapie ansprechender identifizierungsmarker für nierenzellkrebs |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AC | Divisional application: reference to earlier application |
Ref document number: 1599576 Country of ref document: EP Kind code of ref document: P |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| PUAL | Search report despatched |
Free format text: ORIGINAL CODE: 0009013 |
|
| AK | Designated contracting states |
Kind code of ref document: A3 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/68 20060101ALN20120125BHEP Ipc: G06F 19/00 20110101ALI20120125BHEP Ipc: G06F 19/28 20110101AFI20120125BHEP |
|
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1164503 Country of ref document: HK |
|
| 17P | Request for examination filed |
Effective date: 20120820 |
|
| 17Q | First examination report despatched |
Effective date: 20130219 |
|
| GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
| RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12Q 1/68 20060101ALI20150323BHEP Ipc: G06F 19/00 20110101ALI20150323BHEP Ipc: G06F 19/28 20110101AFI20150323BHEP |
|
| INTG | Intention to grant announced |
Effective date: 20150424 |
|
| GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
| GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
| AC | Divisional application: reference to earlier application |
Ref document number: 1599576 Country of ref document: EP Kind code of ref document: P |
|
| AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
| REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP Ref country code: GB Ref legal event code: FG4D |
|
| REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 752803 Country of ref document: AT Kind code of ref document: T Effective date: 20151015 |
|
| REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602004048012 Country of ref document: DE |
|
| REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: RENTSCH PARTNER AG, CH |
|
| REG | Reference to a national code |
Ref country code: DK Ref legal event code: T3 Effective date: 20160108 |
|
| REG | Reference to a national code |
Ref country code: SE Ref legal event code: TRGR |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20151231 |
|
| REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2557885 Country of ref document: ES Kind code of ref document: T3 Effective date: 20160129 |
|
| REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 752803 Country of ref document: AT Kind code of ref document: T Effective date: 20150930 |
|
| REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 13 |
|
| REG | Reference to a national code |
Ref country code: NL Ref legal event code: FP |
|
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: GR Ref document number: 1164503 Country of ref document: HK |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150930 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150930 Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150930 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150930 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150930 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160201 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602004048012 Country of ref document: DE |
|
| PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
| 26N | No opposition filed |
Effective date: 20160701 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150930 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150930 |
|
| REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 14 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: LU Payment date: 20170227 Year of fee payment: 14 |
|
| REG | Reference to a national code |
Ref country code: CH Ref legal event code: PCAR Free format text: NEW ADDRESS: BELLERIVESTRASSE 203 POSTFACH, 8034 ZUERICH (CH) |
|
| REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 15 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 20171228 Year of fee payment: 15 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: NL Payment date: 20180214 Year of fee payment: 15 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DK Payment date: 20180212 Year of fee payment: 15 Ref country code: FI Payment date: 20180209 Year of fee payment: 15 Ref country code: CH Payment date: 20180213 Year of fee payment: 15 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20040220 Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150930 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20180221 Year of fee payment: 15 Ref country code: TR Payment date: 20180212 Year of fee payment: 15 Ref country code: SE Payment date: 20180213 Year of fee payment: 15 Ref country code: IE Payment date: 20180212 Year of fee payment: 15 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150930 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Ref document number: 602004048012 Country of ref document: DE Free format text: PREVIOUS MAIN CLASS: G06F0019280000 Ipc: G16B0050000000 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180220 |
|
| REG | Reference to a national code |
Ref country code: DK Ref legal event code: EBP Effective date: 20190228 |
|
| REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
| REG | Reference to a national code |
Ref country code: SE Ref legal event code: EUG |
|
| REG | Reference to a national code |
Ref country code: NL Ref legal event code: MM Effective date: 20190301 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190221 Ref country code: FI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190220 |
|
| REG | Reference to a national code |
Ref country code: BE Ref legal event code: MM Effective date: 20190228 |
|
| REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190228 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190228 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190301 Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190220 Ref country code: DK Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190228 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190228 Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190220 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20190220 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20230223 Year of fee payment: 20 Ref country code: ES Payment date: 20230323 Year of fee payment: 20 |
|
| PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20230214 Year of fee payment: 20 Ref country code: DE Payment date: 20230227 Year of fee payment: 20 |
|
| P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230613 |
|
| REG | Reference to a national code |
Ref country code: DE Ref legal event code: R071 Ref document number: 602004048012 Country of ref document: DE |
|
| REG | Reference to a national code |
Ref country code: GB Ref legal event code: PE20 Expiry date: 20240219 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20240219 |
|
| REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20240503 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20240221 |
|
| PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20240221 |