Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
  • A61M39/02—Access sites
  • A61M39/04—Access sites having pierceable self-sealing members
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
  • A61M39/02—Access sites
  • A61M39/04—Access sites having pierceable self-sealing members
  • A61M39/045—Access sites having pierceable self-sealing members pre-slit to be pierced by blunt instrument
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
  • A61J1/14—Details; Accessories therefor
  • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
  • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
  • A61M39/10—Tube connectors; Tube couplings
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
  • A61M39/10—Tube connectors; Tube couplings
  • A61M39/16—Tube connectors; Tube couplings having provision for disinfection or sterilisation
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
  • A61M39/20—Closure caps or plugs for connectors or open ends of tubes
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
  • A61M39/22—Valves or arrangement of valves
  • A61M39/26—Valves closing automatically on disconnecting the line and opening on reconnection thereof
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
  • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
  • A61J1/14—Details; Accessories therefor
  • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
  • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
  • A61J1/202—Separating means
  • A61J1/2044—Separating means having slits
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
  • A61M39/10—Tube connectors; Tube couplings
  • A61M2039/1061—Break-apart tubing connectors or couplings
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
  • A61M39/10—Tube connectors; Tube couplings
  • A61M2039/1072—Tube connectors; Tube couplings with a septum present in the connector
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
  • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
  • A61M39/10—Tube connectors; Tube couplings
  • A61M39/1011—Locking means for securing connection; Additional tamper safeties

Definitions

• the invention relates to a device for connecting a syringe to a container or a hose line, in particular for connecting a syringe to a container for receiving infusion, transfusion or enteral nutrient solutions, and in particular for connecting a syringe to a tubing of a blood tubing system of an extracorporeal Blood treatment device or tubing for venous access.
• the invention relates to a container and a hose line with such a device.
• DE-A-197 28 775 describes an infusion bag with an injection part and a removal part.
• the injection part is intended for supplying a medicament by means of a syringe, while the extraction part serves to remove the solution by means of a spike.
• the injection and removal part have a tubular connection part which is closed by a protective cap designed as a break-off part.
• conical connections with a conical shaft and a conical sleeve are known in medical technology whose conical surfaces are normalized.
• the non-lockable conical connections with normalized conical surfaces are referred to as Luer connectors and the lockable conical connections as Luer-Lock connectors.
• the conical luer or luer lock connectors are referred to as male connectors and cones with conical hulls as female connectors.
• An infusion bag with connectors for supplying and removing liquids is also known from DE-A-103 48 016.
• the connector for supplying a liquid allows the connection of a conventional syringe with a conical connection, in particular a luer-lock conical connection, which does not have a hypodermic needle. Since an injection needle with a small cross-section is not required, agents of greater viscosity can be injected quickly. For the nursing staff there is no risk of injury. There is also no risk that the infusion bag is injured. The possibility of screwing the syringe and connector ensures that the connection does not break loose.
• the connector has a self-sealing, slotted membrane that is pierced by the cone shank of the syringe. After pulling out the conical shank, the membrane closes again and thus prevents leakage of the liquid from the bag.
• the connector has proven itself in practice. Proper functioning of the known connector requires, however, that the membrane can be opened easily and safely.
• EP-A-0 681 493 describes a connector for connecting a syringe based on a different functional principle than the connector described above.
• the known connector has a hollow mandrel which is disposed within a plug sealing the connector tightly.
• the mandrel has several lateral openings below its tip.
• EP 0 309 771 A1 describes a device for injecting fluids into a channel of a cannula fitting which has a membrane which is pierced by a cannula upon connection of the cone of a syringe.
• the basic principle is that the conical shaft of the syringe detects a clamping sleeve enclosing the membrane, which is supported on a lower flange of the membrane. As a result, the membrane is pushed over the cannula. Because of the additional clamping sleeve, the production and assembly of the known device is relatively expensive and expensive.
• US Pat. No. 7,360,551 B2 describes an arrangement of connectors in which a membrane of the one connector is penetrated by a hollow body, wherein the hollow body Kö ⁇ er advances in a cylindrical body of the other connector.
• the cylindrical body is not the cone of a syringe.
• the invention has for its object to provide a device that allows easy connection of a syringe to a container or a hose without the risk of injury, the device after removal of the syringe, the container or the hose securely seals.
• the solution of this object is achieved by the features specified in claim 1.
• the device according to the invention has a connection part to be connected to the container or the hose line, which has a recess in which a membrane is arranged, with which the recess is closed.
• a hollow Kö ⁇ er is further arranged with a tip such that the membrane is pierced when connecting the syringe to the connection part.
• the device according to the invention is characterized in that at least the part of the membrane which is pierced, is arranged in the recess of the connecting part above the hollow Kö ⁇ ers, so that when connecting the syringe to the connector part to be pierced part of the membrane on the top of hollow body Kö ⁇ ers is pressed. This ensures that the membrane can be easily and safely pierced without the risk of twisting the membrane exists.
• the conical shank of the syringe and the hollow Kö ⁇ er are arranged such that the Tapering the syringe seals against the hollow body when the syringe is connected to the device.
• the tip of the syringe presses the membrane directly onto the hollow body. The tip of the syringe directly attacks the membrane.
• the conical shaft of the syringe seals not only against the hollow body but also against the connector with the preferably conical fitting of the device, so that both parts are securely sealed against each other, especially when administering Cytostatics is crucial.
• the tip of the syringe is advantageously arranged at a distance from the preferably slotted membrane, an unintentional opening of the membrane is excluded even if both containers should be sterilized with the device according to the invention, the risk of deformation of the membrane due to the pressure in the container consists.
• At least the part of the membrane which is pierced and the hollow body are arranged at a distance from each other in the recess of the connecting part. It is also possible in principle that the tip of the hollow body touches the membrane. The only decisive factor is that the membrane is not damaged by the tip of the hollow body before connecting the syringe to the connector.
• the hollow body, with which the membrane is pierced is formed as a cannula with a ground joint. Consequently, the hollow body need not have any side openings or slits.
• the liquid can flow in the axial direction into the lumen of the cannula.
• a further particularly preferred embodiment of the invention provides that the hollow body is secured in the recess of the connecting part to a disc-shaped body, which preferably has openings.
• the openings in the disc-shaped bodies are preferably circumferentially distributed around the hollow body arranged holes.
• This preferred embodiment has the advantage that the container to which the device is connected can be filled through the openings.
• Another advantage is that if necessary, an injection of additional fluids, such as insulin or heparin, with a syringe with injection needle (cannula), if necessary, also directly through the openings is basically possible.
• the membrane is preferably slotted for sealingly receiving the taper shank of a syringe. This facilitates the piercing of the self-sealing membrane, in particular with a hollow body made of plastic. After pulling out the conical shaft of the syringe, the membrane can close again, so that leakage of the liquid from the container or the hose is prevented. But it is also possible that the membrane is not slotted, especially when the hollow body (mandrel) is a metal mandrel.
• the connecting part preferably has an external thread for connecting a Luer-Lock syringe, which can be securely screwed to the connecting part. But it is also possible that the connection part does not have an external thread, so that only the connection of a Luer syringe without screw thread is possible.
• the connecting part is composed of an upper portion and a lower portion, which are set snapping.
• the disc-shaped body for fixing the hollow-shaped body is preferably arranged at the upper end of the lower portion.
• the membrane is preferably clamped between the upper and lower sections. This simplifies assembly.
• the connection part can also be integral.
• the membrane preferably has an upper dish-shaped section, followed by an annular lower section.
• the lower annular portion of the membrane in this embodiment is preferably clamped between the upper and lower portions of the fitting, while the cup-shaped portion of T / EP2009 / 00685!
• the tip of the hollow body is completely punctured when connecting the syringe.
• the membrane preferably has a trough-shaped depression on the upper side, which on the one hand ensures that the conical shank of the syringe is securely guided and, on the other hand, ensures that the membrane seals securely after the conical shaft has been pulled out.
• the recess of the closing snap-off part of the device according to the invention is advantageously designed as a flat handle to be held with your thumb and forefinger can, whereby the handling is simplified.
• the break-off part can be connected to the connection part of the device via a ring-breaking zone, so that the break-off part has a secure hold, but nevertheless can be loosened relatively easily.
• the device according to the invention is expediently an injection-molded part which can be produced inexpensively in large quantities.
• the container according to the invention for medical fluid is characterized in that the device according to the invention is connected to the container.
• the connection part of the device can be designed differently. Adhesive and / or welded joints are possible.
• the container may be a bag, in particular an infusion or transfusion bag or a bag for receiving an enteral nutrient solution, wherein the connection part may be designed as a closure part to be welded or glued to the bag.
• the container may also be a bottle, wherein the device may be designed as a closure cap or the connection part of the device as an adapter for the closure of a bottle.
• the hose line according to the invention for medical fluids is characterized in that the device according to the invention is connected to the hose line.
• the tubing may, for example, be part of a blood tubing system extracorporeal blood treatment device or tubing for venous access.
• Fig. 1 shows an embodiment of the device according to the invention in the
• FIG. 2 shows a section through the device of Fig. 1 along the line A-A
• FIG. 3 shows a section through the device of Fig. 2 along the line C-C
• FIG. 4 shows the detail A of FIG. 2 in an enlarged view
• FIGS. 1 to 5 shows the device of FIGS. 1 to 5 with connected syringe in a sectional view
• Fig. 7 an infusion or transfusion bag with the invention
• Fig. 9 shows the device of Fig. 8 with connected syringe in cut
• Fig. 12 shows a fourth embodiment of the device according to the invention.
• Fig. 13 shows a fifth embodiment of the device according to the invention.
• Figures 1 to 6 show a first embodiment of the device according to the invention, which is intended for connection of a syringe to a container.
• Figures 1 and 2 show the device according to the invention in side view and in a sectional view, wherein the syringe is not connected to the device.
• the device 1 according to the invention is designed as an injection part for injecting an active substance into a container containing a medicinal liquid, in particular into an infusion or transfusion bag.
• the device according to the invention is therefore a connector 1.
• the connector 1 which is an injection molded part made of polypropylene, has a connection part 2 with a channel-shaped recess 3, which is assembled in the position of use from a bag-side lower portion 4 and a connection-side upper portion 5.
• the lower portion 4 of the connecting part 2 has a lower and upper substantially cylindrical portion 6, 7, wherein the lower portion 6 has a smaller outer diameter than the upper portion 7.
• the lower portion 6 can be inserted or inserted into a connecting piece of a film bag and welded or glued to the socket. But it can also be welded or glued directly into the foil bag without a nozzle.
• the lower and upper part 4, 5 of the connector 1 are snap-connected.
• the upper cylindrical portion 7 of the lower portion 4 of the Connecting part 2 on the outer wall a circumferential projection 8, which snaps into a circumferential groove 9 on the inner wall of the upper portion 5 of the connecting part 2 during compression of the two sections 4, 5.
• the lower edge 10 of the upper portion 5 is supported on a circumferential projection 11 at the lower end of the upper cylindrical portion 7 of the lower portion 4.
• a self-sealing membrane 12 made of an elastic material, which is also referred to as a septum, the same held clamped under elastic deformation.
• the membrane 12 has an annular lower portion 13 which is clamped between the lower and upper part 4, 5 of the connecting part 2.
• an upper plate-shaped portion 14 connects.
• the membrane 12 is provided with a continuous slot 15.
• the membrane 12 may be provided with only a transverse slot or slit also crosswise or star-shaped. The slot preferably extends almost over the entire cross-section of the dish-shaped portion 14 of the membrane.
• the membrane 12 in the center of a trough-shaped depression 16.
• the connecting part 2 is formed as a connecting piece, which has an inner cone 17 and an outer thread 18.
• Inner cone 17 and external thread 18 correspond to the conical shank of a Luer-Lock conical connection of a conventional Luer-Lock syringe, so that the conical shank of the Luer-Lock syringe can be inserted sealingly into the inner cone of the connection piece and securely screwed to the connecting part.
• the break-off part 20 forms a tamper-evident closure for the connector. It has a lower rotationally symmetrical base part 2OA and an upper flat handle piece 2OB.
• the flat handle piece 2OB is provided with a recess 21st provided, which is designed in the manner of a downward arrow, which identifies the connector as Zuspritzteil.
• the connector 1 When connecting a Luer-Lock syringe to the connector, the membrane 12 is pierced.
• the connector 1 has a hollow body 22 with a tip 23.
• the hollow body with the tip is formed as a cannula 22 with a ground 23 having two opposing side facets 23A and 23B.
• the ground cannula 22 is fixed in the center of a disc-shaped body 24, which is integrally formed on the upper end of the lower portion 4 of the connecting part 2.
• the disc-shaped body 24 has a plurality of bores 25, which are arranged distributed circumferentially around the cannula 22.
• the cannula 22 extends from the disc-shaped body 24 of the lower portion 4 of the connecting part 2 in the cylindrical recess 26, which is enclosed by the lower annular portion 13 of the membrane 12. It remains between the bottom of the upper plate-shaped portion 14 of the membrane 12 and the tip 23 of the cannula 22, only a narrow gap 27th
• the lower portion 4 above the peripheral projection 8 has an external toothing 28 and the upper portion 5 has a corresponding internal toothing 29, which engage in the joining of the two parts.
• the break-off part 20 of the connector 2 is turned off or broken off by turning or breaking it, so that the self-sealing membrane 12 is exposed. Then a conventional Luer-Lock syringe is screwed to the connector 2.
• FIG. 6 shows the connector 2 with the break-off part 20 broken off, the Luer-lock syringe 28 being screwed onto the connector, so that a fluid connection is established between the syringe and the connector is made.
• the front end of the conical shaft 29 of the syringe 28 abuts the trough-shaped recess 16 in the plate-shaped portion 14 of the membrane 12.
• the conical shank pushes the upper plate-shaped Section 14 of the membrane 12 down, whereby the membrane with the underside on the tip 23 of the cannula 22 abuts.
• the cannula 22 When the cone shank is advanced further when the syringe is screwed on, the cannula 22 pierces the pre-slit membrane 12, the cannula 22 penetrating into the cylindrical recess 30 of the conical shank 29.
• a narrow gap 31 remains between the conical shaft 29 of the syringe 28 and the disc-shaped body 24 of the lower portion 4 of the connecting part 2.
• the conical shaft 29 is retracted, whereby the upper plate-shaped portion 14th the membrane 12 can go back to its original position to securely close the connector.
• the tip 23 of the cannula 22 can penetrate the membrane 12 without injuring the membrane. This ensures that the membrane reseals the connector when unscrewing the syringe.
• Fig. 7 shows an infusion or transfusion bag 32 together with the connector 1.
• the bag 32 consists of two film layers 32 A and 32 B, which are welded together at the edges 32C. In Fig. 7, only a portion of the bag is shown. In the upper edge of the bag, the connector 1 is welded. The lower portion 4 of the connecting part 2 of the connector 1 is inserted into the connecting piece 32 D and welded to the neck during sterilization.
• the bag 32 can be filled prior to assembly of the connector 1 via the holes 25 in the lower portion 4 of the connecting part 2 with a transfusion or infusion solution, but also an enteral nutrient solution when the lower and upper sections 4, 5 are not yet connected are.
• connection part is designed differently. While the connector of Figs. 1 to 6 intended for connection to a bag is, the devices described below are intended for connection to a bottle or a hose. Since the individual connectors differ only by the design of the connecting part 2, in particular of the lower portion 6 of the lower portion 4 of the connecting part 2, only the differences from the first embodiment of the connector according to the invention will be described below. The corresponding parts are provided in the figures with the same reference numerals.
• FIGS. 8 and 9 show a sectional view of an embodiment of the connector 1 'according to the invention, FIG. 8 showing the connector 1' before connection and FIG. 9 the connector after connection of the syringe 28.
• the lower portion of the lower portion 4 of the connector is formed in this embodiment in the manner of a shuttle 33 which can be welded or glued to a foil bag.
• a shuttle 33 which can be welded or glued to a foil bag.
• Such boats are known in the art. They are formed as a flat body with lateral webs 33A and 33B.
• Fig. 10 shows an embodiment of the device 1 "according to the invention intended for connection to a bottle
• Fig. 11 shows the device 1" connected to the bottle 34.
• the bottle 34 is a conventional bottle for containing a medical fluid sealed with a plug 35.
• the inventive device which is designed as a connection adapter, has a spike 36 for piercing the plug 35 of the bottle 34.
• the spike 36 extends from the upper cylindrical portion 7 of the lower portion 4 of the device down.
• the spike 36 is surrounded by a cylindrical portion 37, which is also integrally formed on the upper portion 7 of the lower portion 4.
• the cylindrical portion 37 has on the inside a plurality of webs 38 and is provided with a plurality of slots 39 so that it can be placed on the closure of the bottle 34.
• the stopper 35 of the bottle is pierced, so that a removal of liquid with a Luer-lock syringe 28 is possible.
• the device 1 '" shows a further exemplary embodiment of the device 1 '"according to the invention, which is intended for connection to a hose line 40, for example a hose line for venous access
• the lower section 6 of the lower section 4 of the device is designed as a hollow-cylindrical connecting piece 41 , which is dimensioned such that the hose 40 can be pushed onto the connecting piece 41 and welded or glued to the socket 12.
• the embodiment of Fig. 12 does not differ in structure and operation from the embodiments described above.
• Fig. 13 shows a further embodiment of the inventive device 1 "", which is designed as a closure cap for a bottle.
• the closure cap has a round cover part 42, to which a cylindrical side part 43 adjoins. At the bottom of the side part 43 is a flange 44 for attaching the cap to the head of a bottle.
• the closure cap 1 "" has a port system 45, which comprises an injection point 46 for injecting liquid and a removal point 47 for withdrawing liquid. Both the injection point 46 and the removal point 47 are closed with a break-off part 48, 49, each of which marks the two points of the port system 45 as an injection or removal point with an arrow 50, 51.
• the lid part 42 and the cylindrical side part 43 constitute the connecting part of the device 1 "" according to the invention, which is placed on the bottle not shown in FIG. 13.
• the round cover part 42 of the closure cap 1 "" has a recess 3 'in which a self-sealing membrane 12' is arranged, with which the recess is closed.
• This membrane is identical to the membrane described with reference to the previous embodiments.
• the membrane 12 ' is pressed onto the tip of a hollow body 22' which is below the membrane 12 'is arranged.
• the tip 23 'of the hollow body 22' is not spaced, but directly below the membrane 12 '.
• the hollow body 22 'for piercing the membrane 12' when connecting the syringe is formed on a disc-shaped body 24 ', which sits together with the membrane in the recess 3' of the cover part 42 of the cap.
• the membrane 12 'and the hollow body 22' with the disk-shaped body 24 ' are clamped in the recess 3' by a projecting circumferential projection 52 which engages under the disk-shaped body 24 '.
• the lower portion of the membrane are based on an upper projecting shoulder 53 and the disk-shaped body on a lower projecting shoulder 54 in the recess 3 'of the cover part 42 of the cap. But it is also possible to glue the disc-shaped body with the cover part of the cap or to weld.
• the removal point 47 of the closure cap does not have the connection according to the invention in this embodiment. Therefore, the removal point of the cap is also not described in detail.

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• Health & Medical Sciences (AREA)
• Heart & Thoracic Surgery (AREA)
• Life Sciences & Earth Sciences (AREA)
• Animal Behavior & Ethology (AREA)
• General Health & Medical Sciences (AREA)
• Public Health (AREA)
• Veterinary Medicine (AREA)
• Pulmonology (AREA)
• Engineering & Computer Science (AREA)
• Anesthesiology (AREA)
• Biomedical Technology (AREA)
• Hematology (AREA)
• Pharmacology & Pharmacy (AREA)
• Epidemiology (AREA)
• Infusion, Injection, And Reservoir Apparatuses (AREA)
• Medical Preparation Storing Or Oral Administration Devices (AREA)

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• 2008
  • 2008-09-25 DE DE200810048988 patent/DE102008048988A1/de not_active Withdrawn
• 2009
  • 2009-09-23 CA CA2738406A patent/CA2738406A1/en not_active Abandoned
  • 2009-09-23 AU AU2009296326A patent/AU2009296326B2/en not_active Ceased
  • 2009-09-23 JP JP2011528236A patent/JP5642076B2/ja not_active Expired - Fee Related
  • 2009-09-23 MX MX2011002902A patent/MX2011002902A/es active IP Right Grant
  • 2009-09-23 BR BRPI0919741A patent/BRPI0919741A2/pt not_active IP Right Cessation
  • 2009-09-23 US US13/061,602 patent/US9108031B2/en not_active Expired - Fee Related
  • 2009-09-23 CN CN200980137567.0A patent/CN102164628B/zh not_active Expired - Fee Related
  • 2009-09-23 EP EP09740054A patent/EP2355888A1/de not_active Withdrawn
  • 2009-09-23 KR KR20117007002A patent/KR20110067023A/ko active IP Right Grant
  • 2009-09-23 WO PCT/EP2009/006851 patent/WO2010034470A1/de active Application Filing
• 2011
  • 2011-04-21 ZA ZA2011/03039A patent/ZA201103039B/en unknown
• 2012
  • 2012-03-05 HK HK12101853.0A patent/HK1161154A1/zh not_active IP Right Cessation

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