EP2197590B1 - Device for separately storing a substance, preferably a medical or pharmaceutical substance, and a liquid and mixing the same prior to the delivery thereof - Google Patents
Device for separately storing a substance, preferably a medical or pharmaceutical substance, and a liquid and mixing the same prior to the delivery thereof Download PDFInfo
- Publication number
- EP2197590B1 EP2197590B1 EP08801309A EP08801309A EP2197590B1 EP 2197590 B1 EP2197590 B1 EP 2197590B1 EP 08801309 A EP08801309 A EP 08801309A EP 08801309 A EP08801309 A EP 08801309A EP 2197590 B1 EP2197590 B1 EP 2197590B1
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- EP
- European Patent Office
- Prior art keywords
- container
- substance
- pump
- liquid
- wall
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/0005—Components or details
- B05B11/0078—Arrangements for separately storing several components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
- B05B11/1042—Components or details
- B05B11/1043—Sealing or attachment arrangements between pump and container
- B05B11/1046—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container
- B05B11/1047—Sealing or attachment arrangements between pump and container the pump chamber being arranged substantially coaxially to the neck of the container the pump being preassembled as an independent unit before being mounted on the container
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B15/00—Details of spraying plant or spraying apparatus not otherwise provided for; Accessories
- B05B15/30—Dip tubes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/0005—Components or details
- B05B11/0027—Means for neutralising the actuation of the sprayer ; Means for preventing access to the sprayer actuation means
Definitions
- the invention relates to an apparatus for separately storing a substance such as a pharmaceutical agent and a liquid, and mixing them before dispensing, with a first container containing the liquid, a second container containing the substance having a bottom to be opened so that the Substance can enter the liquid, and with a device which is advanceable to exert a force on the bottom of the second container, so that it is opened, further comprising a tubular insert which is inserted into a neck of the first container, wherein the front part of a pump device slidably engages in the tubular insert and forms the force-applying device.
- a substance such as a pharmaceutical agent and a liquid
- the substance may be any substance in solid or liquid form which is initially intended to be kept separate from the liquid in the first container and mixed with this liquid before use.
- the substance may be, for example, freeze-dried lactic acid bacteria, which is mixed with a suitable suspension liquid for probiotic applications before use.
- the second container containing the substance is constituted by a tubular insert inserted in the neck of the first container having a bottle shape.
- a predetermined breaking groove is formed, so that the soil can be broken or unfolded by the action of force, so that the substance falls into the liquid of the first container.
- the opening of the floor is accomplished by the front part of an airless pump, which is slidably disposed in the insert. When the airless pump is advanced in the longitudinal direction of the first container, ie pushed into the container, it breaks open the bottom of the insert.
- US 6,230,884 B1 discloses a container cap having a blister pack which is opened by depressing a neck portion of the cap, a pen-like lug pushing a tablet out of the blister pack which falls into the liquid in a bottle. This ambient air can enter the bottle unhindered.
- the US 4,770,323 addresses the problem of providing a sterile package for a fluid which is hermetically sealed by a rupturable sealing membrane until it is first dispensed, allowing unobstructed dispensing of the container contents over a long period of time after rupture of the sealing membrane.
- a tubular perforating member is pushed through the sealing membrane and engages a riser in the container, the riser being connected to a dispensing channel extending through the cap of the package. Even with this packaging, air may enter the package after the sealing membrane breaks open.
- WO 01/30668 A discloses a dispenser according to the preamble of claim 1.
- the dispenser includes on the housing part to which the front part of the pump is fixed, a spaced from the peripheral wall of the pump sealing lip which slidably rests against the inner wall of the container, in which engages the pump part , The task of the sealing lip is to prevent the escape of liquid from the container.
- the housing member which defines an annular air space above the container, is engaged on its cylindrical outer wall either with annular projections in spaced apart annular grooves in the outer side of the neck of the outer container or is in a threaded engagement therewith.
- the present invention has for its object to provide a device in which the above-mentioned malfunctions when pumping the liquid are largely avoided.
- the invention provides that the front part of the pump device is held by a pump housing part, which limits an air space in the retracted initial position of the pump above the tubular insert, and in that in a wall, preferably the peripheral wall of the pump housing part, at least one through the wall Is formed opening through which the air escapes from the decreasing air space to the outside during the advancement of the airless pump, without this air enters the first container.
- the front part of the pump device is sealed at its outer periphery by at least one annular seal against the tubular insert.
- the peripheral wall of the tubular insert has at least one opening passing through the wall, preferably one or more elongated slots, preferably extending from the free end of the tubular insert to about half its height. Through these openings or slots enters the Liquid in the insert and thus in the intake of the pump, wherein at the same time in the interior of the tubular insert located air can escape through these slots.
- the second container is formed by a blister pack which is attached to the tubular insert.
- the substance is sealed in a housing which has a preferably flat bottom and a substantially cup-shaped or bubble-shaped upper chamber wall. To release the substance of the flat bottom or the flat rear wall is broken, wherein the chamber wall is preferably everted through the bottom.
- the bottom wall consists of an aluminum foil or a multilayer foil containing aluminum, and this may also apply to the chamber wall.
- an aluminum-containing multilayer film PE-AL-PVC is mentioned without the invention being limited thereto.
- the chamber wall can be made of LDPE (possibly with an aluminum layer).
- This blister pack is conveniently attached to the tubular insert, which may protrude into the first container.
- the attachment can be done in any suitable manner, for example, by the fact that, for example, 3 to 4 mm wide edge of the blister pack is attached by ultrasonic welding to the lower edge of the insert element, wherein instead of a fastening by hot stamping is possible.
- Other ways of attaching the blister pack are these for example, with an overcap to clamp firmly or to snag with the insert element.
- the attachment can be done in any suitable way.
- the front part of the pump means preferably the suction part of an airless pump, is slidably disposed and constitutes the force applying means with which the bottom of the blister pack can be broken.
- the front part of the pump device is advanced so that the bottom of the blister pack opens inevitably.
- the curved chamber wall of the blister pack can be everted through the broken bottom without being injured or broken up.
- the blister pack further closes the lower opening of the tubular insert.
- a cutting device is attached, which may be formed for example by a sharp-edged metal ring.
- the curved chamber wall of the blister pack is broken or cut.
- the tubular insert forms the second container, as in the DE 197 42 559 C2 the case is.
- the bottom of the second container containing the substance when the bottom of the second container containing the substance is opened by advancing the suction end of the airless pump in the tubular insert, it is prevented that air is pressed into the interior of the liquid container.
- This is independent of whether a blister pack is used as a container for the substance or - as in the case of DE 197 42 559 C2 -
- the tubular insert itself forms the second container and has a réellehyroidden floor.
- FIG. 1 shows the device comprises a bottom cap 1, above a tearing ring 2 for tamper-evident, which is attached to the lower edge of a housing part 3, and an upper cap 4.
- the upper cap 4 covers a generally designated 5 airless pump 5 and is in front of them Remove operation.
- the suction part 9 of the pump 5 is fixed to a pump casing part 11 having a cylindrical peripheral wall 12 abutting the outside of the wall portion 8 of the tubular insert 7 and one at the upper end portion of the pump Suction part 9 adjacent upper wall 12a includes, which define an annular chamber 13 together with the suction part 9 and the top of the tubular insert 7.
- a pump casing part 11 having a cylindrical peripheral wall 12 abutting the outside of the wall portion 8 of the tubular insert 7 and one at the upper end portion of the pump Suction part 9 adjacent upper wall 12a includes, which define an annular chamber 13 together with the suction part 9 and the top of the tubular insert 7.
- holes or slots 14 passing through the wall.
- the insert 7 through the wall penetrating, elongated openings 15, which may extend to the lower edge of the insert 7 or short over it.
- a blister pack 17 is secured in a suitable manner, for example by the edge of the blister pack 17 is welded to the edge 16 of the insert 7.
- the blister pack 17 has a flat lower bottom 18 and an arched chamber wall 19 projecting upwardly into the interior of the insert 7.
- the substance within the blister pack 17 is sealed, and by suitable choice of the material of the walls 18 and 19 vapor diffusion into the interior of the blister pack can be excluded.
- the tear strip 2 is first removed, whereupon the pump 5 can be moved with its suction part 9 in the direction of the blister pack 17.
- the housing part 3 whose outer wall is aligned with the outer walls of the lower cap 1 and the upper cap 4 in threaded engagement with an inwardly offset upper wall portion 21 of the lower cap 1.
- the threaded engagement is in FIG. 3 indicated by the reference numeral 22.
- the housing part 3 can also be rotated with the help of the upper cap 4, which is deducted from the housing part 3 upwards but rotatably connected to this.
- container liquid enters the suction region of the pump part 9, from which any air present therein can easily be displaced.
- FIG. 4 shows that the head end 20 of the suction part 9 of the pump 5 is provided with a cutting ring 24 which has cut the curved chamber wall 19 of the blister pack 17.
- FIG. 4 shows, moreover, details of the airless pump 5, which are known in the art, so that they will not be described here. These details are out FIG. 4 recognizable.
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Closures For Containers (AREA)
- Packages (AREA)
- Package Specialized In Special Use (AREA)
Abstract
Description
Die Erfindung betrifft eine Vorrichtung zum getrennten Aufbewahren einer Substanz wie eines pharmazeutischen Wirkstoffs und einer Flüssigkeit, und zum Mischen derselben vor der Abgabe, mit einem die Flüssigkeit enthaltenden ersten Behälter, einem die Substanz enthaltenden zweiten Behälter, der einen zu öffnenden Boden hat, damit die Substanz in die Flüssigkeit gelangen kann, und mit einer Einrichtung, die vorschiebbar ist, um auf den Boden des zweiten Behälters eine Kraft auszuüben, damit dieser geöffnet wird, ferner mit einem rohrförmigen Einsatz, der in einen Hals des ersten Behälters eingesetzt ist, wobei der vordere Teil einer Pumpeneinrichtung verschieblich in den rohrförmigen Einsatz eingreift und die Kraft ausübende Einrichtung bildet.The invention relates to an apparatus for separately storing a substance such as a pharmaceutical agent and a liquid, and mixing them before dispensing, with a first container containing the liquid, a second container containing the substance having a bottom to be opened so that the Substance can enter the liquid, and with a device which is advanceable to exert a force on the bottom of the second container, so that it is opened, further comprising a tubular insert which is inserted into a neck of the first container, wherein the front part of a pump device slidably engages in the tubular insert and forms the force-applying device.
Bei der Substanz kann es sich um jede Substanz in fester oder auch flüssiger Form handeln, die zunächst von der Flüssigkeit in dem ersten Behälter getrennt aufbewahrt werden soll und vor dem Gebrauch mit dieser Flüssigkeit gemischt wird. Bei der Substanz kann es sich beispielsweise um gefriergetrocknete Milchsäurebakterien handeln, die für probiotische Anwendungen mit einer geeigneten Suspensionsflüssigkeit vermischt wird, bevor die Anwendung erfolgt.The substance may be any substance in solid or liquid form which is initially intended to be kept separate from the liquid in the first container and mixed with this liquid before use. The substance may be, for example, freeze-dried lactic acid bacteria, which is mixed with a suitable suspension liquid for probiotic applications before use.
Eine Vorrichtung der genannten Art ist in der
Bei dieser bekannten Ausbildung tritt das Problem auf, dass beim Vorschieben bzw. Einschieben der Pumpeneinrichtung Luft in den Ansaugbereich der Pumpe gedrückt wird, was zu Funktionsstörungen beim Anpumpen der Flüssigkeit führen kann. Wenn zudem - wie dies bei einigen Anwendungen beispielsweise auf dem medizinischen oder pharmazeutischen Gebiet oder auf dem Gebiet der Hygiene der Fall ist - der Behälterinhalt steril bleiben soll, ist dies mit der vorbekannten Vorrichtung nicht zu gewährleisten, da die beim Vorschub der Pumpe ins Behälterinnere hineingepresste Luft kontaminiert sein kann.In this known training, the problem arises that when advancing or pushing the pump device air is pressed into the intake of the pump, which can lead to malfunction when pumping the liquid. Moreover, if - as is the case with some applications, for example in the medical or pharmaceutical field or in the field of hygiene - the container contents should remain sterile, this can not be guaranteed with the previously known device, since it was pressed into the container interior during the advancement of the pump Air may be contaminated.
Die
Der vorliegenden Erfindung liegt die Aufgabe zugrunde, eine Vorrichtung anzugeben, bei der die oben erwähnten Funktionsstörungen beim Anpumpen der Flüssigkeit weitestgehend vermieden sind.The present invention has for its object to provide a device in which the above-mentioned malfunctions when pumping the liquid are largely avoided.
Diese Aufgabe wird erfindungsgemäß durch die Merkmal des Patentanspruchs 1 gelöst.This object is achieved by the feature of
Vorteilhafte Ausgestaltungen sind in den Unteransprüchen gekennzeichnet.Advantageous embodiments are characterized in the subclaims.
Die Erfindung sieht vor, dass der vordere Teil der Pumpeneinrichtung von einem Pumpengehäuseteil gehalten ist, das in der zurückgezogenen Ausgangsstellung der Pumpe über dem rohrförmigen Einsatz einen Luftraum begrenzt, und dass in einer Wand, vorzugsweise der Umfangswand des Pumpengehäuseteils, wenigstens eine durch die Wand durchgehende Öffnung ausgebildet ist, durch die beim Vorschub der Airless-Pumpe die Luft aus dem sich verkleinernden Luftraum nach außen entweicht, ohne dass diese Luft in den ersten Behälter eintritt. Hierzu ist außerdem erfindungsgemäß vorgesehen, dass der vordere Teil der Pumpeneinrichtung an seinem Außenumfang durch wenigstens eine Ringdichtung gegenüber dem rohrförmigen Einsatz abgedichtet ist.The invention provides that the front part of the pump device is held by a pump housing part, which limits an air space in the retracted initial position of the pump above the tubular insert, and in that in a wall, preferably the peripheral wall of the pump housing part, at least one through the wall Is formed opening through which the air escapes from the decreasing air space to the outside during the advancement of the airless pump, without this air enters the first container. For this purpose, it is also provided according to the invention that the front part of the pump device is sealed at its outer periphery by at least one annular seal against the tubular insert.
Durch diese Ausbildung ist erreicht, dass Funktionsstörungen beim Anpumpen der Airless-Pumpe vermieden sind, da beim Vorschub der Pumpe in die Gebrauchsstellung keine Luft in den Ansaugraum der Pumpe eintritt. Außerdem wird die Sterilität des Behälterinhalts nicht durch Eintritt von evtl. kontaminierter Luft in Frage gestellt.This design ensures that malfunctions when pumping the airless pump are avoided because when the pump is moved to the position of use no air enters the suction chamber of the pump. In addition, the sterility of the container contents is not questioned by the entry of possibly contaminated air.
Des weiteren wird mit Vorteil vorgeschlagen, dass die Umfangswand des rohrförmigen Einsatzes wenigstens eine durch die Wand hindurchgehende Öffnung, vorzugsweise einen oder mehrere lang gestreckte Schlitze aufweist, die sich vorzugsweise vom freien Ende des rohrförmigen Einsatzes bis etwa zu dessen halber Höhe erstrecken. Durch diese Öffnungen oder Schlitze tritt die Flüssigkeit in den Einsatz und damit in den Ansaugbereich der Pumpe ein, wobei gleichzeitig im Innenraum des rohrförmigen Einsatzes befindliche Luft durch diese Schlitze austreten kann.Furthermore, it is advantageously proposed that the peripheral wall of the tubular insert has at least one opening passing through the wall, preferably one or more elongated slots, preferably extending from the free end of the tubular insert to about half its height. Through these openings or slots enters the Liquid in the insert and thus in the intake of the pump, wherein at the same time in the interior of the tubular insert located air can escape through these slots.
Diese Ausbildung hat zur Folge, dass bei der erstmaligen Inbetriebnahme der Vorrichtung bereits ein oder zwei Pumpvorgänge der Airlesspumpe ausreichen, um Behälterinhalt abzugeben.As a result of this design, when the device is first put into operation, one or two pumping operations of the airless pump are sufficient to dispense container contents.
In weiterer Ausgestaltung der Erfindung kann vorgesehen sein, dass der zweite Behälter durch eine Blisterpackung gebildet ist, die an dem rohrförmigen Einsatz befestigt ist. Dabei ist die Substanz in ein Gehäuse eingesiegelt, das einen vorzugsweise ebenen Boden und eine im wesentlichen napfförmige oder blasenförmige obere Kammerwand hat. Zur Freigabe der Substanz wird der ebene Boden bzw. die ebene Rückwand aufgebrochen, wobei die Kammerwand vorzugsweise durch den Boden hindurch umgestülpt wird.In a further embodiment of the invention can be provided that the second container is formed by a blister pack which is attached to the tubular insert. In this case, the substance is sealed in a housing which has a preferably flat bottom and a substantially cup-shaped or bubble-shaped upper chamber wall. To release the substance of the flat bottom or the flat rear wall is broken, wherein the chamber wall is preferably everted through the bottom.
Wenn die Substanz - beispielsweise ein medizinischer oder pharmazeutischer Wirkstoff - sicher gegen eindringende Feuchtigkeit zu schützen ist, besteht zumindest die Bodenwand aus einer Aluminiumfolie oder einer Aluminium enthaltenden Mehrschichtfolie, wobei dies auch für die Kammerwand zutreffen kann. Als Beispiel für eine Aluminium enthaltende Mehrschichtfolie wird PE-AL-PVC genannt, ohne dass die Erfindung hierauf beschränkt ist. Die Kammerwand kann aus LDPE (evtl. mit einer Aluminiumschicht versehen) bestehen.If the substance - for example a medicinal or pharmaceutical active substance - is to be protected reliably against penetrating moisture, at least the bottom wall consists of an aluminum foil or a multilayer foil containing aluminum, and this may also apply to the chamber wall. As an example of an aluminum-containing multilayer film, PE-AL-PVC is mentioned without the invention being limited thereto. The chamber wall can be made of LDPE (possibly with an aluminum layer).
Diese Blisterpackung ist zweckmäßigerweise an dem rohrförmigen Einsatz befestigt, der in den ersten Behälter hineinragen kann.This blister pack is conveniently attached to the tubular insert, which may protrude into the first container.
Die Befestigung kann auf jede geeignete Weise erfolgen, beispielsweise dadurch, dass der z.B. 3 bis 4 mm breite Rand der Blisterpackung durch Ultraschallschweißen an dem unteren Rand des Einsatzelementes angebracht ist, wobei statt dessen auch eine Befestigung durch Heißprägen möglich ist. Weitere Möglichkeiten der Befestigung der Blisterpackung bestehen darin, diese beispielsweise mit einer Überkappe fest zu klemmen oder mit dem Einsatzelement zu verschnappen. Wie gesagt, kann die Befestigung auf jede geeignete Art erfolgen.The attachment can be done in any suitable manner, for example, by the fact that, for example, 3 to 4 mm wide edge of the blister pack is attached by ultrasonic welding to the lower edge of the insert element, wherein instead of a fastening by hot stamping is possible. Other ways of attaching the blister pack are these for example, with an overcap to clamp firmly or to snag with the insert element. As mentioned, the attachment can be done in any suitable way.
Der vordere Teil der Pumpeneinrichtung, vorzugsweise der Saugteil einer Airless-Pumpe, ist verschieblich angeordnet und bildet die Kraft ausübende Einrichtung, mit der der Boden der Blisterpackung aufgebrochen werden kann. Hierzu wird der vordere Teil der Pumpeneinrichtung so vorgeschoben, dass sich der Boden der Blisterpackung zwangsläufig öffnet.The front part of the pump means, preferably the suction part of an airless pump, is slidably disposed and constitutes the force applying means with which the bottom of the blister pack can be broken. For this purpose, the front part of the pump device is advanced so that the bottom of the blister pack opens inevitably.
Hierbei kann die gewölbte Kammerwand der Blisterpackung durch den aufgebrochenen Boden hindurch umgestülpt werden, ohne dabei selbst verletzt bzw. aufgebrochen zu werden. In diesem Fall verschließt die Blisterpackung weiterhin die untere Öffnung des rohrförmigen Einsatzes.In this case, the curved chamber wall of the blister pack can be everted through the broken bottom without being injured or broken up. In this case, the blister pack further closes the lower opening of the tubular insert.
Es kann aber auch vorgesehen sein, dass an dem freien Ende des vorderen Teils der Pumpeneinrichtung eine Schneideinrichtung befestigt ist, die beispielsweise durch einen scharfkantigen Metallring gebildet sein kann. In diesem Fall wird auch die gewölbte Kammerwand der Blisterpackung aufgebrochen bzw. aufgeschnitten.But it can also be provided that at the free end of the front part of the pump device, a cutting device is attached, which may be formed for example by a sharp-edged metal ring. In this case, the curved chamber wall of the blister pack is broken or cut.
In einer alternativen Ausgestaltung der Erfindung bildet der rohrförmige Einsatz den zweiten Behälter, wie dies bei der
Gemäß der Erfindung ist verhindert, dass beim Öffnen des Bodens des die Substanz enthaltenden zweiten Behälters durch Vorschub des Saugendes der Airlesspumpe in dem rohrförmigen Einsatz Luft ins Innere des Flüssigkeitsbehälters gepresst wird. Dies ist unabhängig davon, ob als Behälter für die Substanz eine Blisterpackung verwendet wird oder - wie im Falle der
Weitere Einzelheiten der Erfindung ergeben sich aus der nachfolgenden Beschreibung von bevorzugten Ausführungsformen der Erfindung sowie anhand der Zeichnungen. Dabei zeigen:
Figur 1- eine Seitenansicht einer Ausführungsform der erfindungsgemäßen Vorrichtung;
Figur 2- einen Schnitt A-A durch die Vorrichtung gemäß
;Figur 1 Figur 3- eine vergrößerte Darstellung des eingekreisten Bereichs der
;Figur 2 - Figur 4
- eine Darstellung
ähnlich Figur 3 , jedoch in der Gebrauchsstellung der Airless-Pumpe und
- FIG. 1
- a side view of an embodiment of the device according to the invention;
- FIG. 2
- a section AA through the device according to
FIG. 1 ; - FIG. 3
- an enlarged view of the circled area of
FIG. 2 ; - FIG. 4
- a representation similar
FIG. 3 , but in the position of use of the airless pump and
Wie
In der Bodenkappe 1 sitzt - drehfest mit dieser verbunden - ein etwa flaschenförmiger Behälter 6, in dem sich eine Flüssigkeit befindet. In den Hals des Behälters 6 ist ein rohrförmiger Einsatz 7 eingesetzt, der den Behälterhals mit einem ringförmigen äußeren Wandabschnitt 8 übergreift. In dem Einsatz 7 sitzt verschieblich der vordere Teil oder Saugteil 9 der Airless-Pumpe 5. Am oberen Randbereich des Einsatzes 7 befindet sich eine Ringdichtung 10, die den Zwischenraum zwischen der Innenwand des Einsatzes 7 und der Außenwand des Saugteils 9 der Pumpe 5 abdichtet.In the
Das Saugteil 9 der Pumpe 5 ist an einem Pumpengehäuseteil 11 befestigt, das eine zylindrische Umfangswand 12, die an der Außenseite des Wandabschnitts 8 des rohrförmigen Einsatzes 7 anliegt, und eine an dem oberen Endbereich des Saugteils 9 anliegende obere Wand 12a enthält, die zusammen mit dem Saugteil 9 und der Oberseite des rohrförmigen Einsatzes 7 eine ringförmige Kammer 13 begrenzen. In der Umfangswand 12 des Pumpengehäuseteils 11 befinden sich durch die Wand hindurchgehende Löcher oder Schlitze 14.The suction part 9 of the
Im unteren Bereich enthält auch der Einsatz 7 durch die Wand hindurchgehende, langgestreckte Öffnungen 15, die sich bis zum unteren Rand des Einsatzes 7 erstrecken können oder kurz darüber enden.In the lower part also contains the
An dem unteren Rand 16 des Einsatzes 7 ist eine Blisterpackung 17 auf geeignete Weise befestigt, beispielsweise indem der Rand der Blisterpackung 17 an dem Rand 16 des Einsatzes 7 festgeschweißt ist. Die Blisterpackung 1 7 hat einen ebenen unteren Boden 18 und eine nach oben ins Innere des Einsatzes 7 hineinragende gewölbte Kammerwand 19. Die Substanz innerhalb der Blisterpackung 17 ist eingesiegelt, wobei durch geeignete Wahl des Materials der Wände 18 und 19 eine Dampfdiffusion ins Innere der Blisterpackung ausgeschlossen werden kann.At the
In der in den
Zum Vermischen der Substanz der Blisterpackung 17 mit der in dem Behälter 6 bzw. in einem Innenbeutel des Behälters 6 befindlichen Flüssigkeit wird zunächst der Abreißstreifen 2 entfernt, woraufhin die Pumpe 5 mit ihrem Saugteil 9 in Richtung der Blisterpackung 17 bewegt werden kann. Hierzu steht das Gehäuseteil 3, deren Außenwand mit den Außenwänden der unteren Kappe 1 und der oberen Kappe 4 fluchtet im Gewindeeingriff mit einem nach innen versetzten oberen Wandabschnitt 21 der unteren Kappe 1. Der Gewindeeingriff ist in
Wenn das Gehäuseteil 3 auf dem Wandabschnitt 21 nach unten geschraubt wird, nimmt sein radial innerer Ringabschnitt 23 gleichzeitig dasWhen the
Pumpengehäuseteil 11 und damit den Saugteil 9 der Pumpe 5 nach unten mit, wobei das Kopfende 20 des Saugteils 9 auf die Blisterpackung 17 auftrifft, die Bodenwand 18 aufreißt und die obere Kammerwand 19 nach unten stülpt. Dieser Zustand ist in
Bei diesem Vorgang wird Luft aus dem Ringraum 13 durch die Wandöffnungen 14 verdrängt, ohne dass diese Luft wegen der Ringdichtung 10 ins Innere des rohrförmigen Einsatzes 7 gelangt.In this process, air is displaced from the
Durch die Schlitze 15 tritt Behälterflüssigkeit in den Saugbereich des Pumpenteils 9 ein, aus dem evtl. darin befindliche Luft leicht verdrängt werden kann.Through the
Es wird betont, dass die Erfindung nicht auf die beschriebenen und dargestellten Ausführungsformen beschränkt ist. Vielmehr sind alle offenbarten Merkmale auf jede sinnvolle Weise einzeln miteinander kombinierbar.It is emphasized that the invention is not limited to the described and illustrated embodiments. Rather, all disclosed features can be individually combined with each other in any meaningful way.
Claims (5)
- Apparatus for separately storing a substance, such as a pharmaceutically active substance, and a liquid and for mixing the same before dispensing including a first container (6) containing the liquid, a second container (17) containing the substance, which has a base (18) which is to be opened so that the substance can get into the liquid, and including a device which may be advanced in order to exert a force on the base (18) of the second container (17) so that it is opened and also including a tubular insert (7), which is inserted into a throat of the first container (6), wherein the front portion (9) of a pump device (6) movably engages in the tubular insert (7) and constitutes the force-exerting device and wherein the front portion (9) of the pump device (5) is held by a pump housing portion (11), which, in the retracted starting position of the pump device (5) above the tubular insert (7), bounds an air space (13), characterised in that formed in a wall of the pump housing portion (11) there is at least one opening (14) passing through the wall, through which air outside the first container (6) escapes when the pump device (5) is advanced and that situated at the upper edge of the insert (7) there is an annular seal (10), which seals the space between the inner wall of the insert (7) and the outer wall of the suction portion (9) of the pump (5) in an air-tight manner.
- Apparatus as claimed in claim 1, characterised in that the peripheral wall of the tubular insert (7) affords at least one opening, preferably at least two slots (15).
- Apparatus as claimed in claim 1, characterised in that fastened to the free end (20) of the front portion (9) of the pump device (5) there is a cutting device (24).
- Apparatus as claimed in one of claims 1 to 3, characterised in that the second container is a blister package (17), which is secured to the tubular insert (7), which projects into the first container (6).
- Apparatus as claimed in claim 1 or 3, characterised in that the tubular insert (7) constitutes the second container.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102007046625A DE102007046625B4 (en) | 2007-09-27 | 2007-09-27 | Device for the separate storage of a substance, preferably a medicinal or pharmaceutical active substance, and a liquid and for mixing the same before use |
PCT/DE2008/001505 WO2009039821A1 (en) | 2007-09-27 | 2008-09-08 | Device for separately storing a substance, preferably a medical or pharmaceutical substance, and a liquid and mixing the same prior to the delivery thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2197590A1 EP2197590A1 (en) | 2010-06-23 |
EP2197590B1 true EP2197590B1 (en) | 2011-11-02 |
Family
ID=40344835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP08801309A Not-in-force EP2197590B1 (en) | 2007-09-27 | 2008-09-08 | Device for separately storing a substance, preferably a medical or pharmaceutical substance, and a liquid and mixing the same prior to the delivery thereof |
Country Status (13)
Country | Link |
---|---|
US (1) | US8267280B2 (en) |
EP (1) | EP2197590B1 (en) |
JP (1) | JP5605781B2 (en) |
CN (1) | CN101855023B (en) |
AT (1) | ATE531460T1 (en) |
AU (1) | AU2008302828B2 (en) |
BR (1) | BRPI0815960A8 (en) |
CA (1) | CA2701051C (en) |
DE (1) | DE102007046625B4 (en) |
ES (1) | ES2375085T3 (en) |
MX (1) | MX338713B (en) |
RU (1) | RU2438797C1 (en) |
WO (1) | WO2009039821A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102010009101A1 (en) | 2010-02-24 | 2011-08-25 | GAPLAST GmbH, 82442 | packaging |
DE102010009102B4 (en) | 2010-02-24 | 2014-08-28 | Gaplast Gmbh | Double-walled squeeze bottle with valve in the airless system |
US8141700B2 (en) * | 2010-05-28 | 2012-03-27 | Tap the Cap, Inc. | Bottle cap for dispersing powdered supplement in situ |
KR101192603B1 (en) * | 2010-11-22 | 2012-10-26 | (주)연우 | Cosmetic vessel having mixed two-type materials |
WO2015080252A1 (en) * | 2013-11-29 | 2015-06-04 | 株式会社ダイゾー | Content-accommodating container, content-accommodating product using same, discharging product, and discharging device |
FR3016617B1 (en) * | 2014-01-17 | 2016-02-19 | Aptar France Sas | FLUID PRODUCT TANK AND DISPENSER INTEGRATING SUCH TANK. |
EP2957347B1 (en) * | 2014-06-18 | 2017-02-22 | Albea Thomaston Inc. | System for dispensing a mixture of a first product and a second product |
KR101619957B1 (en) * | 2015-04-10 | 2016-05-12 | (주)연우 | Cosmetic vessel having mixed two-type materials |
CN107912034B (en) * | 2015-04-27 | 2019-10-18 | 麦克罗盖亚生物科技有限公司 | Mixer plug |
FR3042181B1 (en) * | 2015-10-08 | 2020-02-28 | Qualipac | DEVICE FOR PACKAGING AND DISPENSING BY DOSE OF A FLUID PRODUCT |
CN106829184B (en) * | 2017-01-20 | 2019-04-02 | 付佳琦 | A kind of mixing vessel and production method of solute and liquid |
FR3089431B1 (en) * | 2018-12-05 | 2021-01-01 | Qualipac Sa | PACKAGING AND DISTRIBUTION DEVICE PER DOSE OF A FLUID PRODUCT, INCLUDING A REUSABLE BOTTLE |
CN210556616U (en) * | 2019-10-11 | 2020-05-19 | 浙江越甲药业有限公司 | Bottle and bottle cap device thereof |
CN110934794B (en) * | 2019-12-18 | 2021-07-16 | 宁夏艾伊生物工程研发有限公司 | Shampoo special for industrial enterprises |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3080094A (en) * | 1958-04-29 | 1963-03-05 | Modern Lab Inc | Compartmented pressurized container valve assembly and a cutter therefor |
US3172568A (en) * | 1959-03-27 | 1965-03-09 | Modern Lab Inc | Pressurized dispensing device |
US3655096A (en) * | 1969-10-22 | 1972-04-11 | Pillsbury Co | Container for diluting and dispensing material |
FR2593147B1 (en) * | 1986-01-17 | 1988-03-18 | Aerosol Inventions Dev | STERILE PACKAGING OF LIQUID AND SEMI-LIQUID FLUID SUBSTANCES. |
IT1259853B (en) * | 1992-12-09 | 1996-03-28 | Bernardino Parise | CONTAINER FOR CONCENTRATED SUBSTANCES IN POWDER OR LIQUID TO BE PUT IN SOLUTION WITHIN A WRAPPER AT THE TIME OF USE |
US5642838A (en) * | 1995-12-28 | 1997-07-01 | Stoody; William Robert | Frangible sealing lid for spile access |
ES2221159T3 (en) * | 1997-03-12 | 2004-12-16 | Fredrick Coory | DOWNLOAD CAPERUTA WITH DISPOSABLE BASKET CONTAINING TABLETS. |
DE19742559C2 (en) * | 1997-09-26 | 1999-08-05 | Gaplast Gmbh | Container with a pump |
US6098795A (en) * | 1997-10-14 | 2000-08-08 | Mollstam; Bo | Device for adding a component to a package |
FR2800360B1 (en) * | 1999-10-29 | 2002-01-18 | Valois Sa | EXTEMPORANE MIXTURE DISPENSER |
KR200266847Y1 (en) * | 2001-12-05 | 2002-03-04 | (주)연우 | dispenser |
-
2007
- 2007-09-27 DE DE102007046625A patent/DE102007046625B4/en active Active
-
2008
- 2008-09-08 AT AT08801309T patent/ATE531460T1/en active
- 2008-09-08 CN CN2008801156062A patent/CN101855023B/en not_active Expired - Fee Related
- 2008-09-08 RU RU2010116416/05A patent/RU2438797C1/en not_active IP Right Cessation
- 2008-09-08 MX MX2010003344A patent/MX338713B/en active IP Right Grant
- 2008-09-08 EP EP08801309A patent/EP2197590B1/en not_active Not-in-force
- 2008-09-08 ES ES08801309T patent/ES2375085T3/en active Active
- 2008-09-08 CA CA2701051A patent/CA2701051C/en not_active Expired - Fee Related
- 2008-09-08 AU AU2008302828A patent/AU2008302828B2/en not_active Ceased
- 2008-09-08 JP JP2010526152A patent/JP5605781B2/en not_active Expired - Fee Related
- 2008-09-08 WO PCT/DE2008/001505 patent/WO2009039821A1/en active Application Filing
- 2008-09-08 US US12/680,457 patent/US8267280B2/en active Active
- 2008-09-08 BR BRPI0815960A patent/BRPI0815960A8/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE531460T1 (en) | 2011-11-15 |
JP5605781B2 (en) | 2014-10-15 |
JP2011501721A (en) | 2011-01-13 |
BRPI0815960A8 (en) | 2018-04-17 |
BRPI0815960A2 (en) | 2018-02-14 |
MX2010003344A (en) | 2010-05-03 |
CN101855023A (en) | 2010-10-06 |
DE102007046625A1 (en) | 2009-04-09 |
MX338713B (en) | 2016-04-28 |
WO2009039821A1 (en) | 2009-04-02 |
EP2197590A1 (en) | 2010-06-23 |
AU2008302828A1 (en) | 2009-04-02 |
US20100219202A1 (en) | 2010-09-02 |
AU2008302828B2 (en) | 2013-03-07 |
CA2701051C (en) | 2016-02-02 |
CN101855023B (en) | 2013-03-13 |
ES2375085T3 (en) | 2012-02-24 |
RU2010116416A (en) | 2011-11-10 |
US8267280B2 (en) | 2012-09-18 |
DE102007046625B4 (en) | 2012-06-06 |
CA2701051A1 (en) | 2009-04-02 |
RU2438797C1 (en) | 2012-01-10 |
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