EP2066609A4 - Procédé de préparation d'éther éthylique de fluorométhyl 2,2,2-trifluoro-1-(trifluorométhyle) - Google Patents
Procédé de préparation d'éther éthylique de fluorométhyl 2,2,2-trifluoro-1-(trifluorométhyle)Info
- Publication number
- EP2066609A4 EP2066609A4 EP20060790484 EP06790484A EP2066609A4 EP 2066609 A4 EP2066609 A4 EP 2066609A4 EP 20060790484 EP20060790484 EP 20060790484 EP 06790484 A EP06790484 A EP 06790484A EP 2066609 A4 EP2066609 A4 EP 2066609A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- fluoromethyl
- trifluoro
- trifluoromethyl
- preparation
- ethyl ether
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/34—Separation; Purification; Stabilisation; Use of additives
- C07C41/44—Separation; Purification; Stabilisation; Use of additives by treatments giving rise to a chemical modification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/BR2006/000198 WO2008037040A2 (fr) | 2006-09-29 | 2006-09-29 | Procédé de préparation d'éther éthylique de fluorométhyl 2,2,2-trifluoro-1-(trifluorométhyle) |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2066609A2 EP2066609A2 (fr) | 2009-06-10 |
EP2066609A4 true EP2066609A4 (fr) | 2010-04-28 |
EP2066609B1 EP2066609B1 (fr) | 2016-01-06 |
Family
ID=39230552
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06790484.7A Not-in-force EP2066609B1 (fr) | 2006-09-29 | 2006-09-29 | Procédé de préparation d'éther éthylique de fluorométhyl 2,2,2-trifluoro-1-(trifluorométhyle) |
Country Status (8)
Country | Link |
---|---|
US (1) | US8044247B2 (fr) |
EP (1) | EP2066609B1 (fr) |
JP (1) | JP5021745B2 (fr) |
CN (1) | CN101679169B (fr) |
BR (1) | BRPI0622034B1 (fr) |
HK (1) | HK1142588A1 (fr) |
MX (1) | MX2009003354A (fr) |
WO (1) | WO2008037040A2 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2069278B1 (fr) * | 2006-09-29 | 2016-01-06 | Cristália Produtos Químicos Farmacêuticos Ltda. | Procédé de préparation d'éther éthylique de chlorométhyl 2,2,2-trifluoro-1-(trifluorométhyle) |
CN101314560B (zh) * | 2008-07-02 | 2011-06-15 | 鲁南制药集团股份有限公司 | 七氟烷的合成方法 |
CN101462929B (zh) * | 2009-01-08 | 2011-07-20 | 中国中化集团公司 | 用作吸入麻醉剂的异氟醚的制备方法 |
CA2769797A1 (fr) | 2009-08-10 | 2011-02-17 | Solvay Fluor Gmbh | Procede de fabrication de sevoflurane |
CN102199076B (zh) * | 2010-03-25 | 2014-05-14 | 上海源力生物技术有限公司 | 制备七氟烷的方法 |
US8729313B2 (en) * | 2011-08-15 | 2014-05-20 | Baxter International Inc. | Process for the manufacturing of sevoflurane |
RU2479566C1 (ru) * | 2012-01-11 | 2013-04-20 | Общество с ограниченной ответственностью "Пермская химическая компания" | Способ получения севофлурана |
CN103360222A (zh) * | 2013-07-29 | 2013-10-23 | 中国科学院上海有机化学研究所 | 2,2,2-三氟乙基1,1,2,3,3,3-六氟丙基醚的制备 |
CN107698430B (zh) * | 2017-11-01 | 2021-01-08 | 华东医药(西安)博华制药有限公司 | 一种七氟烷反应液的后处理方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0822172A1 (fr) * | 1996-02-21 | 1998-02-04 | Central Glass Company, Limited | Procede de preparation de l'ether de fluoromethyle 1,1,1,3,3,3-hexafluoro-isopropylique |
US6100434A (en) * | 1999-03-26 | 2000-08-08 | Abbott Laboratories | Method for synthesizing sevoflurane and an intermediate thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL32586A (en) | 1968-10-28 | 1973-11-28 | Baxter Laboratories Inc | 1,3-polyhalo-2-propyl methyl and halomethyl ethers and their preparation |
US3689571A (en) | 1970-07-31 | 1972-09-05 | Baxter Laboratories Inc | Fluorinated ether |
FR2416237A1 (fr) * | 1978-02-01 | 1979-08-31 | Dia Prosim | Procede de chloromethylation de polymeres en vue de la preparation de resines echangeuses d'ions anioniques |
JPS6049170B2 (ja) * | 1979-10-31 | 1985-10-31 | 株式会社クラレ | β−アルコキシエトキシメチルハライドの製造方法 |
MX2007005899A (es) * | 2004-11-17 | 2007-07-24 | Minrad Inc | Metodo para la preparacion de sevoflurano. |
-
2006
- 2006-09-29 JP JP2009529473A patent/JP5021745B2/ja not_active Expired - Fee Related
- 2006-09-29 MX MX2009003354A patent/MX2009003354A/es active IP Right Grant
- 2006-09-29 CN CN2006800563471A patent/CN101679169B/zh active Active
- 2006-09-29 EP EP06790484.7A patent/EP2066609B1/fr not_active Not-in-force
- 2006-09-29 US US12/443,440 patent/US8044247B2/en not_active Expired - Fee Related
- 2006-09-29 BR BRPI0622034-7A patent/BRPI0622034B1/pt active IP Right Grant
- 2006-09-29 WO PCT/BR2006/000198 patent/WO2008037040A2/fr active Application Filing
-
2010
- 2010-09-21 HK HK10109030.1A patent/HK1142588A1/xx not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0822172A1 (fr) * | 1996-02-21 | 1998-02-04 | Central Glass Company, Limited | Procede de preparation de l'ether de fluoromethyle 1,1,1,3,3,3-hexafluoro-isopropylique |
US6100434A (en) * | 1999-03-26 | 2000-08-08 | Abbott Laboratories | Method for synthesizing sevoflurane and an intermediate thereof |
Non-Patent Citations (1)
Title |
---|
See also references of WO2008037040A2 * |
Also Published As
Publication number | Publication date |
---|---|
US20090247791A1 (en) | 2009-10-01 |
HK1142588A1 (en) | 2010-12-10 |
WO2008037040A2 (fr) | 2008-04-03 |
WO2008037040A3 (fr) | 2009-02-12 |
EP2066609B1 (fr) | 2016-01-06 |
CN101679169B (zh) | 2012-12-19 |
JP5021745B2 (ja) | 2012-09-12 |
US8044247B2 (en) | 2011-10-25 |
EP2066609A2 (fr) | 2009-06-10 |
MX2009003354A (es) | 2009-04-14 |
BRPI0622034B1 (pt) | 2021-06-22 |
CN101679169A (zh) | 2010-03-24 |
JP2010504917A (ja) | 2010-02-18 |
BRPI0622034A2 (pt) | 2014-04-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1142588A1 (en) | Process for the preparation of fluoromethyl 2,2,2-trifluoro-1- (trifluoromethyl) ethyl ether | |
SI1797037T1 (sl) | Postopek priprave 4-(4-((((4-kloro-3-(trifluorometil)fenil)amino)karbonil)amino) fenioksi)N-metilpiridin-2-karboksamida | |
DK3872059T3 (en) | Process for the preparation of 2,3,3,3 tetrahydrofluoropropene | |
PL1993985T3 (pl) | Sposób wytwarzania 1,2-propanodiolu | |
HK1135087A1 (en) | Process for the preparation of chloromethyl 2,2,2-trifluoro-1- (trifluoromethyl) ethyl ether | |
AP2350A (en) | Method for the preparation of sevoflurane. | |
EP2368871B8 (fr) | Procédé d'élaboration de (1R,2R)-3-(3-diméthylamino-1-éthyl-2-méthyl-propyl)-phénol | |
ZA200700925B (en) | Process for the preparation of polymorphs of mesotrione | |
HK1201822A1 (en) | Process for the preparation of 5,6-dihydro-1h-pyridin-2-one compounds 56--1h--2- | |
SI1844036T1 (sl) | Postopek za pripravo aripiprazola | |
EP2231574A4 (fr) | Procédé de purification d'éther fluorométhyl 1,1,1,3,3,3-hexafluoro-isopropylique (sévoflurane) | |
PT1976960E (pt) | Processo para a preparação de biodiesel | |
ZA200810509B (en) | Process for the preparation of pure dimethyl ether | |
HK1144682A1 (en) | Process for the preparation of alkyl 3,3-dialkoxypropionates 33- | |
SI2044099T1 (sl) | Postopek priprave S-fluorometil-6,9-difluoro-11-hidroksi-16-metil-17-propioniloksi-3-okso -androsta-1,4-dien-17-karbotioata in vmesnih spojin | |
AP2277A (en) | Process for production of 1,2,2,2-tertafluoro ethyl difluoro methyl ether. | |
EP2343269A4 (fr) | Méthode de production de fluorométhyl-1,1,1,3,3,3-hexafluoroisopropyléther | |
EP1996192A4 (fr) | Procede de preparation de thiazolidin-2-ones bi-substitues en 3,4 | |
IL193068A0 (en) | Process for the stereoselective preparation of alcohols from alpha, beta-insaturated compounds | |
EP2084168A4 (fr) | Processus pour la préparation de composés dialkyldithiophosphiniques hautement purifiés | |
AP2440A (en) | A process for the preparation of dispiro 1,2,4-trioxolane antimalarials 'OZ277' | |
ZA201003264B (en) | Method for the preparation of 2 chloro1,1,1,2,3,3,3 heptafluopropane | |
IL187658A0 (en) | Process for the preparation of 3,7-dihydroxy-1,5-diazacyclooctanes | |
IL177353A0 (en) | Process for the preparation of aq4n | |
EP1915380A4 (fr) | Procédé de synthèse d oxabispidines n,n´-disubstituées |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20090327 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20100325 |
|
17Q | First examination report despatched |
Effective date: 20100525 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07C 41/01 20060101ALI20150811BHEP Ipc: C07C 41/05 20060101ALI20150811BHEP Ipc: C07C 41/22 20060101AFI20150811BHEP Ipc: C07C 41/44 20060101ALI20150811BHEP Ipc: C07C 43/12 20060101ALI20150811BHEP |
|
INTG | Intention to grant announced |
Effective date: 20150826 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 768709 Country of ref document: AT Kind code of ref document: T Effective date: 20160215 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602006047673 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: MP Effective date: 20160106 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 768709 Country of ref document: AT Kind code of ref document: T Effective date: 20160106 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160407 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160506 Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: PL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160506 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602006047673 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 |
|
26N | No opposition filed |
Effective date: 20161007 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160406 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R119 Ref document number: 602006047673 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20160929 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: ST Effective date: 20170531 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20170401 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160930 Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160930 Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160929 Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160929 Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160930 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20160929 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20060929 Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20160106 |