EP2011127B1 - Aimant courbé à guidage de faisceau à bobines supraconductrices en forme de selle et de trajectoire de course et installation d'irradiation équipée d'un aimant de ce type - Google Patents
Aimant courbé à guidage de faisceau à bobines supraconductrices en forme de selle et de trajectoire de course et installation d'irradiation équipée d'un aimant de ce type Download PDFInfo
- Publication number
- EP2011127B1 EP2011127B1 EP07712257A EP07712257A EP2011127B1 EP 2011127 B1 EP2011127 B1 EP 2011127B1 EP 07712257 A EP07712257 A EP 07712257A EP 07712257 A EP07712257 A EP 07712257A EP 2011127 B1 EP2011127 B1 EP 2011127B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- guiding
- magnet
- coils
- curved
- irradiation machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Not-in-force
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Classifications
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H7/00—Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
- H05H7/04—Magnet systems, e.g. undulators, wigglers; Energisation thereof
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
- G21K1/00—Arrangements for handling particles or ionising radiation, e.g. focusing or moderating
- G21K1/08—Deviation, concentration or focusing of the beam by electric or magnetic means
- G21K1/093—Deviation, concentration or focusing of the beam by electric or magnetic means by magnetic means
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
- G21K5/00—Irradiation devices
- G21K5/04—Irradiation devices with beam-forming means
Definitions
- a corresponding irradiation system is z. B. from the WO 02/069350 A1 or the DE 199 04 675 A1 out.
- Curved beam guiding magnets are widely used in particle accelerator systems for deflecting and / or focusing a beam of charged particles, such as electrons or ions.
- such systems can also be designed for radiotherapy in the field of medical technology.
- a corresponding therapy system goes from the mentioned DE 199 04 675 A1 or the US 4,870,287 out. It comprises a particle source or an accelerator for generating a high-energy particle beam which emerges from the source in the direction of an irradiation axis and onto a region of a subject to be irradiated such. B. a tumor of a patient is addressed.
- the beam is in a so-called "gantry" by means of an array of different deflection and focusing magnets repeatedly deflected from the direction of the original irradiation axis so that it at a predetermined angle with respect to this axis, in particular at 45 to 90 °, to be irradiated on the Area occurs.
- the magnet arrangement of deflection and focusing magnets is arranged on a frame of the gantry and rotatable around the original irradiation direction as a rotation axis or gantry rotation axis, whereby the exiting beam is always guided through a fixed point in the so-called called "isocenter" runs and so the exposure to radiation in the surrounding area or tissue can be limited by distribution over a relatively large area.
- the radius of curvature and the magnet length of the commonly used magnets with deflection / bending angles of 45 ° to 90 ° are in this case for the case of irradiation with C 6+ ions at a few meters. With these dimensions, however, the weight of the iron yokes of the magnets is correspondingly high. So z. As the magnets of a known gantry system a total weight of about 95 t. The required bogie for the pivoting magnets of such a gantry system must be carried out accordingly stable and thereby ensure an accurate beam guidance.
- the DE 43 35 807 A1 discloses a superconductive deflection magnet apparatus for deflecting an electron beam.
- This device has a magnetic shield surrounding a cryostat. In the cryostat two groups of coils are arranged. Overall, the deflection electromagnet device comprises two main coils and four and six pole correction coils.
- the superconducting magnet coils are cooled within the cryostat in a refrigerant bath, preferably a bath of liquid helium.
- the EP 0 208 163 A1 discloses a magnetic field device for a system for accelerating and / or storing electrically charged particles.
- the electrically charged particles in particular electrons, are deflected with the specified magnetic field device along a curved particle path.
- the magnetic field device has superconducting windings which generate a dipole.
- the magnetic Guide field which is effective on the particle beam should act in particular with respect to this focusing.
- the US 6,403,967 B1 discloses a device with a magnet system for ion implantation.
- the magnet system serves to generate a dipole field for deflecting the ion beam.
- the corresponding device has in particular specially shaped ferromagnetic yokes for magnetic field shaping.
- the US 5,111,173 discloses a charged particle deflection magnet suitable for a synchrotron, for example.
- a 180 ° deflection magnet is provided with superconducting coils which are suitable for generating a magnetic field which is improved in terms of its homogeneity.
- the object of the present invention is to specify an irradiation system with at least one beam guiding magnet, wherein the beam guiding magnet should have reduced values with respect to its size and its weight compared with corresponding normal conducting magnets.
- the beam guiding magnet 2 serves for deflecting a particle beam 3 indicated by a broken line about a central curvature or arc angle ⁇ , which is preferably between 30 ° and 90 ° (ie with 30 ° ⁇ ⁇ 90 °).
- the particle beam 3 is a beam of electrically charged particles, such as ions, in particular C 6+ ions.
- the particle beam is held or guided by means of magnetic forces within a correspondingly curved beam guiding tube 5.
- the curved path of the particle beam defines a beam guiding plane 6, which in FIG. 2 should be indicated by a dashed line.
- superconductors are used to construct the magnet windings or coils of the beam guiding magnet 2.
- known materials for superconductors usable here are known metallic LTC (Low T c ) superconductor materials such.
- a He cooling technique is generally required for LTC superconductors, for example at operating temperatures of about 4.2 K, higher operating temperatures of, for example, 10 to 40 K, preferably 20 to 30 K may be provided when using HTC superconductors.
- known HTC superconductors to generate the required magnetic field strengths sufficiently high critical current densities.
- For the required cooling of the superconductor can be made of known refrigeration equipment.
- a system of at least six superconducting individual coils has to be provided, of which in each case two are formed and arranged in pairs in mirror image to the beam guidance plane 6.
- the system comprises on individual coils two in the beam-guiding direction elongated, saddle-shaped, hereinafter referred to as main coils Coils 8 and 9. These coils each have two curved, laterally to the beam guide tube 5 extending side parts 8a, 8b and 9a, 9b and end-side end portions 8c, 8d and 9c, 9d.
- the end-side end parts are preferably each bent or bent from the plane spanned by the side parts of the main spool such that they lead around the beam-guiding tube 5 in each case in the manner of a semicircle.
- the design form of corresponding main coils is generally known (cf. EP 0 276 360 B1 ).
- other known saddle shapes are suitable, which lie on a curved cylinder jacket surface. That is to say, the side parts 8a, 8b and 9a, 9b need not each extend exactly in a non-curved plane and / or the front end parts 8c, 8db or 9c, 9d do not necessarily have to be exactly semicircular in shape, but can also be formed parabolic-like shape (cf. JP 02-246305 A ).
- secondary coils coils 10 and 11 are provided in parallel planes. These coils are designed as curved racetrack coils and preferably extend between the end, winding-like end portions of the main coils 8 and 9.
- the design form corresponding, here for example, about 90 ° curved banana-shaped secondary coils is also known (see. EP 0 185 955 B1 or DE 35 04 211 A1 ).
- the conductors of the secondary coils 10 and 11 each enclose a banana-shaped curved inner region 12 or 13 and there each a correspondingly curved, hereinafter referred to as additional coil 14 and 15 also of the racetrack type. How out FIG. 2 As can be seen, the winding cross-section of these additional coils 14 and 15 is significantly smaller than that of the sub-coils 10 and 11 respectively enclosing them. In this figure, also the current flow directions in the coils 10, 11, 14 and 15 are indicated.
- the individual coils can be assigned more coils to required field conditions z. B. with regard to homogeneity on. However, with the minimum number of six coils, generally satisfactory field conditions can be achieved.
- thermal insulation means comprise as shown in FIG. 2 a trained as a vacuum or cryostat housing warm outer housing 17 which includes a vacuum space 18.
- a cold inner vessel 20 within this vacuum space is a cold inner vessel 20, in which a holding structure 21 for receiving and fixing the individual superconducting coils is arranged.
- the conductors of the individual superconducting coils the required cooling capacity must be provided for their cooling, for example via a refrigerant in a suitable manner.
- FIG. 2 is also indicated, between the cold inner vessel 20 and the warm outer housing 17 in the vacuum chamber 18 even more, even discretely cooled insulation means such as radiation shields or insulating films 22 are provided.
- FIG. 3 shows a lateral view of the made in the beam guide plane longitudinal section through a corresponding beam guiding magnet 2 with a curvature angle ⁇ of 90 °.
- the leading out of this plane angle heads or end portions of one of the saddle-shaped main coils, for example, the semi-circular arc-like end portions 8c and 8d of the coil 8 are particularly highlighted.
- the support structure 21 for the main coil 8 is provided with special reinforcing ribs 23. These parts are located within the cold inner vessel 20, the z. B. for receiving a liquid refrigerant such as He or Ne serves.
- the inner vessel is equipped with front end flanges 25 and 26. In a corresponding manner, end-face end flanges 27 and 28 are also provided for the warm outer housing 17.
- the secondary coils 10 and 11 and the additional coils 14 and 15 are formed as completely flat, lying in a plane, banana-shaped curved racetrack coils.
- at least partially these coils are designed only approximately flat. This is understood to mean that the coils can also be bent saddle-shaped at least in the region of their arcuate end parts. The coils are then no longer in a flat plane but on a lateral surface of a cylinder which surrounds the curved beam guide axis 4.
- Such coils can be produced, for example, from initially flat, curved racetrack coils by then being adapted in a form-fitting manner to the lateral surface of the curved cylinder.
- FIGS. 1 to 3 described curved beam guiding magnet 2 is suitable for any irradiation facilities for the deflection of rays of any electrically charged particles per se (see, for. US 4,870,287 A or JP 2000-075100 A ). It is preferably provided for a gantry system which serves for medical therapy.
- the design features of corresponding systems are also generally known (cf. DE 199 04 675 A1 or WO 02/069350 A1 ).
- Such a system is characterized in that its end focusing and deflection magnets to a gantry rotation axis are designed pivotally. Only the pivotable deflection of such a system are in FIG. 4 indicated in a highly schematic representation.
- the gantry system generally designated 30, has an irradiation source 31, which is not detailed in the figure, for generating a beam 3 of ions, in particular C 6+ ions. These ions emerge from the source in a beam-guiding direction, which at the same time defines the gantry rotation axis A.
- the ion beam 3 is brought into a region remote from the axis A and from there through an inventively formed, for example by 90 ° deflecting deflection or beam guiding magnet 2 is directed in a direction perpendicular to the axis of rotation A direction where it intersects the axis A in an isocenter 35.
- deflection magnets such. B. from a 45 ° magnet and a 135 ° magnet or two 30 ° magnets and a 120 ° magnet suitable.
- one of the beam 3 traversed by means of an iron box magnetically shielded diagnostic head for the beam position and the radiation dose is designated 36.
- FIG. 4 For comparison purposes is also in the FIG. 4 indicated by dashed lines another magnet system 38, which would result if instead of a system of superconducting magnets corresponding normal conducting magnets would be used with field-forming iron yokes.
- the isocenter 35 would then be located about 1 m farther from the ion source 31, based on the values shown in the following table: embodiment conventional superconducting magnet technology Cu conductor and iron LTC or HTC conductor Aperture field B max 1.8 Tesla 4-5 Tesla field shaping iron yoke Air coils without iron Magnetic material (1 90 ° magnet, 2 45 ° magnets) about 95 t about 6 tons Power consumption at B max 830 kW 15-30 kW Gantry diameter x gantry length ⁇ 12 mx 18 m ⁇ 7 mx 12 m
- FIG. 4 and the table above immediately shows the advantage of using superconducting magnets in a gantry plant as an irradiation facility.
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- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Optics & Photonics (AREA)
- Plasma & Fusion (AREA)
- Particle Accelerators (AREA)
- Radiation-Therapy Devices (AREA)
Claims (8)
- Installation (30) d'exposition à un rayonnement, comprenant
une source 31 de rayonnement fixe et produisant un faisceau (3) de particules chargées électriquement et un système Gantry comprenant au moins un
aimant ( 2 ) de guidage du faisceau pour dévier le faisceau ( 3 ) de particules chargées électriquement le long d'une trajectoire ( 4 ) de particules courbée, dans laquelle- la trajectoire ( 4 ) de particules courbée fixe un plan ( 6 ) de guidage du faisceau,- le système Gantry peut tourner autour d'un axe ( A ) passant dans le plan ( 6 ) de guidage du faisceau,
et- l'aimant ( 2 ) de guidage du faisceau est exempt de matériau ferromagnétique et influençant le guidage du faisceau et est pourvua) d'un tube ( 5 ) de guidage du faisceau courbé et entourant la trajectoire ( 6 ) de particules courbée,b) d'un système associé au tube ( 5 ) de guidage du faisceau d'au moins six bobines individuelles supraconductrices courbées et s'étendant dans la direction de guidage du faisceau de particules, qui sont formées et disposées par paire d'une manière symétrique comme en un miroir, par rapport au plan ( 6 ) de guidage du faisceau, le système de bobine comprenant au moins :- deux bobines ( 8, 9 ) principales en forme de selle ayant des parties ( 8a, 8b et 9a, 9b ) latérales s'étendant en longueur dans la direction de guidage du faisceau, et des parties (8c, 8d et 9c, 9d) courbées d'extrémité, du côté frontal,- deux bobines ( 10, 11 ) auxiliaires plates courbées en forme de banane, du type à piste de course, qui entourent respectivement une zone ( 12 et 13 ) intérieure,- deux bobines ( 14, 15 ) supplémentaires, de type à piste de course, courbées en forme de banane et disposées respectivement dans la partie ( 12, 13 ) intérieure des bobines ( 10, 11 ) auxiliaires respectives,
etc) de moyens d'isolation thermique et de moyens de refroidissement des diverses bobines supraconductrices. - Installation ( 30 ) d'exposition à un rayonnement suivant la revendication 1, caractérisée par un aimant ( 2 ) de guidage du faisceau ayant un angle ( α ) de courbure au centre compris entre 30° et 90°.
- Installation ( 30 ) d'exposition à un rayonnement suivant la revendication 1 ou 2, caractérisée en ce que les bobines ( 10, 11 ) auxiliaires de l'aimant (12) de guidage du faisceau s'étendent entre les parties (8c, 8d et 9c, 9d ) courbées d'extrémité de leur bobine ( 8 et 9 ) principale associée respectivement.
- Installation (30) d'exposition à un rayonnement suivant l'une des revendications précédentes, caractérisée en ce que les conducteurs des bobines individuelles de l'aimant ( 2 ) de guidage du faisceau ont des matériaux supraconducteurs LTC métalliques.
- Installation (30) d'exposition à un rayonnement suivant l'une des revendications 1 à 3, caractérisée en ce que les conducteurs des diverses bobines de l'aimant ( 2 ) de guidage du faisceau ont des matériaux supraconducteurs HTC en oxyde métallique.
- Installation ( 30 ) d'exposition à un rayonnement suivant la revendication 5, caractérisée par une température de fonctionnement des conducteurs des diverses bobines comprise entre 10 K et 40 K, de préférence entre 20 K et 30 K.
- Installation (30) d'exposition à un rayonnement suivant l'une des revendications précédentes, caractérisée en ce que le faisceau ( 3 ) de particules contient des particules C6+.
- Installation (30) d'exposition à un rayonnement suivant l'une des revendications précédentes, caractérisée par une intensité du champ magnétique d'ouverture de l'aimant ( 2 ) de guidage du faisceau dans son tube ( 5 ) de guide du faisceau d'au moins 2 Tesla, de préférence compris entre 3 et 5 Tesla.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006018635A DE102006018635B4 (de) | 2006-04-21 | 2006-04-21 | Bestrahlungsanlage mit einem Gantry-System mit einem gekrümmten Strahlführungsmagneten |
PCT/EP2007/051642 WO2007122025A1 (fr) | 2006-04-21 | 2007-02-21 | Aimant courbé à guidage de faisceau à bobines supraconductrices en forme de selle et de trajectoire de course et installation d'irradiation équipée d'un aimant de ce type |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2011127A1 EP2011127A1 (fr) | 2009-01-07 |
EP2011127B1 true EP2011127B1 (fr) | 2011-04-20 |
Family
ID=37951500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07712257A Not-in-force EP2011127B1 (fr) | 2006-04-21 | 2007-02-21 | Aimant courbé à guidage de faisceau à bobines supraconductrices en forme de selle et de trajectoire de course et installation d'irradiation équipée d'un aimant de ce type |
Country Status (5)
Country | Link |
---|---|
US (1) | US20090091409A1 (fr) |
EP (1) | EP2011127B1 (fr) |
AT (1) | ATE506679T1 (fr) |
DE (2) | DE102006018635B4 (fr) |
WO (1) | WO2007122025A1 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102007021033B3 (de) * | 2007-05-04 | 2009-03-05 | Siemens Ag | Strahlführungsmagnet zur Ablenkung eines Strahls elektrisch geladener Teilchen längs einer gekrümmten Teilchenbahn und Bestrahlungsanlage mit einem solchen Magneten |
DE102007025584B4 (de) * | 2007-06-01 | 2009-05-14 | Siemens Ag | Strahlungsführungsmagnet zur Ablenkung eines Strahls elektrisch geladener Teilchen längs einer gekrümmten Teilchenbahn und Bestrahlungsanlage mit einem solchen Magneten |
DE102007046508B4 (de) | 2007-09-28 | 2010-01-21 | Siemens Ag | Bestrahlungsanlage mit einem Strahlführungsmagneten |
DE102007050035B4 (de) * | 2007-10-17 | 2015-10-08 | Siemens Aktiengesellschaft | Vorrichtung und Verfahren zur Ablenkung eines Strahls elektrisch geladener Teilchen auf eine gekrümmte Teilchenbahn |
EP2283711B1 (fr) * | 2008-05-22 | 2018-07-11 | Vladimir Yegorovich Balakin | Dispositif d'acceleration d'un faisceau de particules chargees faisant partie d'un systeme de traitement anticancereux par particules chargees |
DE102010012073B4 (de) * | 2010-03-19 | 2012-05-31 | Karlsruher Institut für Technologie | Vorrichtung zur Verringerung der Erwärmung einer Vakuumkammer |
CN103140013B (zh) * | 2013-02-06 | 2015-04-15 | 江苏海明医疗器械有限公司 | 高能电子束消色散偏转装置 |
CN104124055B (zh) * | 2014-07-17 | 2016-05-04 | 中国科学院近代物理研究所 | 窗口型不规则马鞍形线圈的绕线装置及绕制方法 |
JP6460922B2 (ja) * | 2015-06-16 | 2019-01-30 | 株式会社日立製作所 | ビーム用超電導偏向電磁石およびそれを用いたビーム偏向装置 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0185955B1 (fr) * | 1984-12-10 | 1988-05-25 | Siemens Aktiengesellschaft | Procédé pour fabriquer une bobine magnétique en forme de disque cambré et dispositifs pour exécuter ce procédé |
DE3504211A1 (de) * | 1985-02-07 | 1986-08-07 | Siemens AG, 1000 Berlin und 8000 München | Verfahren zur herstellung einer gekruemmten magnetspule und vorrichtung zur durchfuehrung dieses verfahrens |
EP0208163B1 (fr) * | 1985-06-24 | 1989-01-04 | Siemens Aktiengesellschaft | Dispositif à champ magnétique pour un appareil d'accélération et/ou de stockage de particules chargées |
EP0276360B1 (fr) * | 1987-01-28 | 1993-06-09 | Siemens Aktiengesellschaft | Dispositif magnétique à bobines courbées |
JPS63304606A (ja) * | 1987-06-03 | 1988-12-12 | Sumitomo Electric Ind Ltd | 酸化物超伝導2極マグネットコイル |
US4870287A (en) * | 1988-03-03 | 1989-09-26 | Loma Linda University Medical Center | Multi-station proton beam therapy system |
JP2896188B2 (ja) * | 1990-03-27 | 1999-05-31 | 三菱電機株式会社 | 荷電粒子装置用偏向電磁石 |
US5153546A (en) * | 1991-06-03 | 1992-10-06 | General Electric Company | Open MRI magnet |
JP2549233B2 (ja) * | 1992-10-21 | 1996-10-30 | 三菱電機株式会社 | 超電導電磁石装置 |
US5442928A (en) * | 1994-08-05 | 1995-08-22 | General Electric | Hybrid cooling system for a superconducting magnet |
US5446433A (en) * | 1994-09-21 | 1995-08-29 | General Electric Company | Superconducting magnet having a shock-resistant support structure |
DE19904675A1 (de) * | 1999-02-04 | 2000-08-10 | Schwerionenforsch Gmbh | Gantry-System und Verfahren zum Betrieb des Systems |
US6509819B2 (en) * | 1999-07-23 | 2003-01-21 | American Superconductor Corporation | Rotor assembly including superconducting magnetic coil |
US6403967B1 (en) * | 1999-10-15 | 2002-06-11 | Advanced Ion Beam Technology, Inc. | Magnet system for an ion beam implantation system using high perveance beams |
US6770888B1 (en) * | 2003-05-15 | 2004-08-03 | Axcelis Technologies, Inc. | High mass resolution magnet for ribbon beam ion implanters |
ATE384553T1 (de) * | 2003-12-02 | 2008-02-15 | Radinova Ab | Mehrzimmer-strahlungsbehandlungssystem |
US7170377B2 (en) * | 2004-07-28 | 2007-01-30 | General Electric Company | Superconductive magnet including a cryocooler coldhead |
WO2007130164A2 (fr) * | 2006-01-19 | 2007-11-15 | Massachusetts Institute Of Technology | Synchrocyclotron supraconducteur à champ élevé |
DE102006035101A1 (de) * | 2006-07-28 | 2008-02-07 | Siemens Ag | Strahlführungsmagnet zur Ablenkung geladener Teilchen längs einer gekrümmten Bahn mit zugeordneter Kühlvorrichtung und Bestrahlungsanlage mit einem solchen Magneten |
-
2006
- 2006-04-21 DE DE102006018635A patent/DE102006018635B4/de not_active Expired - Fee Related
-
2007
- 2007-02-21 US US12/297,374 patent/US20090091409A1/en not_active Abandoned
- 2007-02-21 DE DE502007006995T patent/DE502007006995D1/de active Active
- 2007-02-21 EP EP07712257A patent/EP2011127B1/fr not_active Not-in-force
- 2007-02-21 AT AT07712257T patent/ATE506679T1/de active
- 2007-02-21 WO PCT/EP2007/051642 patent/WO2007122025A1/fr active Application Filing
Non-Patent Citations (1)
Title |
---|
PRIANO C. ET AL: "A superconducting magnet for a beam delivery system for carbon ion cancer therapy", IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, vol. 12, no. 1, March 2002 (2002-03-01), pages 988 - 992, XP011069190 * |
Also Published As
Publication number | Publication date |
---|---|
DE102006018635B4 (de) | 2008-01-24 |
ATE506679T1 (de) | 2011-05-15 |
DE502007006995D1 (de) | 2011-06-01 |
DE102006018635A1 (de) | 2007-10-25 |
EP2011127A1 (fr) | 2009-01-07 |
US20090091409A1 (en) | 2009-04-09 |
WO2007122025A1 (fr) | 2007-11-01 |
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