EP1742649A1 - Complexes de substances actives provenant de plantes de la famille du varech, en particulier de la famille zosteraceae, son procede de production et son utilisation - Google Patents

Complexes de substances actives provenant de plantes de la famille du varech, en particulier de la famille zosteraceae, son procede de production et son utilisation

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Publication number
EP1742649A1
EP1742649A1 EP05716999A EP05716999A EP1742649A1 EP 1742649 A1 EP1742649 A1 EP 1742649A1 EP 05716999 A EP05716999 A EP 05716999A EP 05716999 A EP05716999 A EP 05716999A EP 1742649 A1 EP1742649 A1 EP 1742649A1
Authority
EP
European Patent Office
Prior art keywords
active ingredient
production
plants
complexes according
powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05716999A
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German (de)
English (en)
Inventor
Christel Dr. Dötsch-Jutsch
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Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102004012455A external-priority patent/DE102004012455A1/de
Application filed by Individual filed Critical Individual
Publication of EP1742649A1 publication Critical patent/EP1742649A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40—Colouring or decolouring of foods
    • A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706—Algae
    • A61K8/9722—Chlorophycota or Chlorophyta [green algae], e.g. Chlorella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • the invention relates to complexes of active substances from seaweed plants, in particular the Zosteraceae family, obtainable by producing spissum extracts from these plants or by converting the plants by air jet grinding into a herbal drug powder.
  • the complexes of active ingredients can be used as food, nutritional supplements or pharmaceuticals, medicinal, spa and luxury foods as well as for applications of thalasso and wellness therapies from the area of Healthcare & Wellbeing, generally for products in the healthcare industry.
  • the invention also relates to the use of the active ingredient complexes from dried whole seaweed plants for certain forms of use.
  • Marine flower plants are - like other marine organisms - characterized by special ingredients adapted to marine life (Lindequist, U. and Th. Schweder: Marine Biotechnology, in: Biotechnology. Z. Ed., Ed. H.- J. Rehm Wiley-NCH Weinheim 2001, pp. 442-473). This also applies to the sea grass. These include the 4 plant families of seaweed plants in the narrower sense, which include marine species of the Hydrocharitaceae, the Cymodoceaceae, the Posidoniaceae and the Zosteraceae. The Ruppiaceae with four marine species of the genus Ruppia are also classified as sea grasses. The use of the ingredients has been described in various marine plants for different applications.
  • the Zosteraceae family are submerged living flowering plants. They occur worldwide in two genera (Zostera and Phyllospadix) and of them the genus Zostera in 9 species, in the shallow water area on the coasts of the oceans to a depth of 12 m, predominantly in 4 m water depth (Green EP and Short FT (2003 ): World Atlas of Seagrasses. University of California Press, Berkeley, USA. Pp. 263-286). In addition to the general enormous importance of sea grass meadows as a habitat for fish and other marine organisms, they serve to feed certain marine animals and to stabilize marine sediments.
  • Seagrass is washed up in certain weather conditions as beach goods - especially on the beaches of the Baltic Sea - to a large extent and therefore stands as Raw material source available inexpensively.
  • the Baltic Sea is a species of the Zostera genus. There is therefore no wild collection from the sea that would not be necessary due to the threat to the existence or protection status (Fleischhauer, SG: Encyclopedia of edible wild plants, AT Verlag, Aarau and Kunststoff, 2003, p. 376).
  • sea grasses have been used centuries ago because of their extraordinary properties as insulating and filling materials. Properties that are favorable for this application include, above all, the good sound and heat insulating effect, good rot resistance and flame resistance.
  • the use of seagrass of the Zostera genus in products for use as insulating and insulating material and in products against vermin and bugs has been protected by patent (US 4016084 A, CA 1 096 193 A).
  • the state of the art also includes the use of coarsely powdered or chopped seaweed in body packs (utility model DE 20008 368 Ul).
  • Extracts of herbs have been used for millennia for ner use as cosmetic additives and flavors in the manufacture of cosmetic creams, ointments and other beauty care products.
  • the Nerwerty of ingredients marine higher flowering plants such as the species from the Baltic Sea from the plant family of the seaweed family, Zosteraceae, for
  • JP 4139108 AA (“Cosmetics”) is the use of
  • Genera Zostera reported the Japanese species Zostera asiatica, Zostera japonica, Zostera caespitosa, which can be used for the production of cosmetics, ha the detailed description of the disclosure;
  • the design also relates to the use of seaweed.
  • the Japanese invention only includes such effects of extracts from the seaweed, which essentially describe the heat content, moisture and the reduction of freckles.
  • other_technological processes and completely different processes in the production of raw materials and cosmetics are described.
  • the object of the present invention is to enable further use of ingredients of sea grasses, in particular the Zosteraceae family, and in particular the Zostera genus.
  • Spissum extracts are obtained from the corresponding plants.
  • the production of spissum extracts is known in principle from Gaedcke, F. and Barabara Steinhoff: Phytopharmaka, WVG Stuttgart, 2000, p. 4.
  • a spissum extract is a viscous preparation. It lies in the consistency between fluid and dry extracts. This form of preparation has the advantage of being able to introduce the plant with all of its information, but in a highly concentrated form. it?
  • the active ingredient complexes according to the invention are used as a concentrate completely natural without any addition of preservatives and other substances.
  • preservatives for certain dosage forms, the use of a food preservative is possible.
  • the previous extracts were concentrated until the production of so-called “dry extracts” and brought back into solution for the subsequent further production process.
  • the spissum extract for nutritional products thus represents a pure marine natural product in a highly concentrated form, which is used in this form for all fields of the food and beverage sector (health food, nutraceuticals, functional food, etc.).
  • the object of the invention was achieved by an active ingredient complex from plants of the seaweed, preferably the Zosteraceae family, in particular the Zostera genus, vegetable herbal powder being used by a special micronization process by air jet grinding of the raw material be won.
  • An air jet mill is preferably used.
  • the product according to the invention is characterized by its method of manufacture and has the advantage over the prior art that the result obtained gives excellent powder homogeneity (see analysis protocol, FIG. 1).
  • FIG. 1 shows the grain size distribution of a seagrass fraction which was ground to a fine powder after the preliminary comminution with an air jet mill from Jet Mill Inc./USA.
  • Extracts can be produced from the naturally occurring sea grass with solvents of different polarities.
  • Known extraction agents such as cold and hot water or ethanol or a mixture of water and ethanol can be used.
  • the active substance complexes can also contain other organisms.
  • a special embodiment of the invention is the combination of seaweed with the Algae chlorella, a unicellular green microalgae.
  • the addition of sea buckthorn is also possible (application example 10).
  • the present invention thus also relates to a composition comprising seaweed and chlorella or seaweed and sea buckthorn.
  • halophytes salt plants
  • salt-tolerant or salt-loving (halophilic) plants they occur as grasses, succulents, trees, in bush and shrub formations in many saline hacks on coasts, dunes, salt marshes, deserts, steppes, brackish water areas, etc.
  • salt-tolerant or salt-loving (halophilic) plants they occur as grasses, succulents, trees, in bush and shrub formations in many saline hacks on coasts, dunes, salt marshes, deserts, steppes, brackish water areas, etc.
  • common to all is the high adaptation to salt, from the tropics to the tundra.
  • the hydro-halophytes grow in brackish water areas and on salty wetlands, the dry-adapted (xero-halophytes) occur in deserts and low-moisture areas of the world.
  • plants of the genera Salicomia, Spartina, Suaeda, Beta and Crambe are particularly known, of which the skar Salicomia spp. (Also known as sea asparagus, also known as sea asparagus) used as a vegetable in gastronomy be.
  • Salico ia also occurs on the Baltic Sea and thus offers an innovative potential for new product developments for joint use with Zostera marina.
  • the present invention thus also relates to a composition comprising seaweed and halophytes.
  • Spirulina is a blue-green algae and therefore not harmless because it can lead to toxicological effects.
  • the genus Spirulina is a cyanobacterium (blue-green algae) and thus a primitive organism in terms of development, although it is similar to the unicellular microalgae, eg the green algae Chlorella, green in color; externally, however, Spirulina uaid Chlorella can hardly be distinguished from one another in products from the food supplement sector.
  • spirulina can produce toxins that can be fatal under certain circumstances. Seaweed does not have this disadvantage because it is a higher flowering plant that is unable to produce bacterial toxins. Similarly, no seaweed has any known toxins.
  • An inventive use of the active ingredient complexes lies in the field of the food sector (health food, nutraceuticals, functional food, etc.).
  • the active substance complexes according to the invention have an antimicrobial effect. They are suitable for the prevention and therapy of bacterial infections.
  • the use of the active ingredient complexes is possible for various diseases.
  • a typical application for the prophylaxis xmd / or therapy of herpes diseases is particularly advantageous.
  • the use of the active ingredient complexes from the Zosteraceae family solves problems that have recently arisen in human and veterinary medicine in combating multi-resistant bacteria, in particular MRSA (multi-resistant SVtaphylococcus aureus), in hospitals and other institutions which have a represent a highly infectious source of danger.
  • MRSA multi-resistant SVtaphylococcus aureus
  • the expansion of the range of new products with antimicrobial substances is very important in order to provide agents with antimicrobial effects and different application properties in a cost-effective form for human and veterinary medicine. This applies in particular to agents that are effective even with multi-resistant gram-positive germs.
  • staphylococcal infections play a major role, especially in cattle farming, since the germs are easily transmitted during milking and can contaminate the milk.
  • the active ingredient complexes can be used locally. By using the active ingredient complexes on the udder, a transmission of staphylococcal infections can be prevented and contamination of the milk can be avoided.
  • the use according to the invention as medicaments which contain the active substance complexes is based on the proven biological effects. They can be particularly advantageous for the manufacture of a medicament for the targeted prophylaxis and treatment of gram-positive infections and viral infections.
  • a use of the active ingredient complexes according to the invention lies in the field of agrotechnology in the areas of plant and animal production and in the area of soil remediation.
  • the use of the highly specialized active ingredients as fertilizer additions, for the targeted improvement of the mineral supply of soils and as a feed additive in silage additives, supplementary feed, mixed feed and special feed can lead to a significant improvement in animal health.
  • adding seaweed Zostera marina to the feed which has high levels of Ca and Mg, can increase the hardness of egg shells and the quality and color of the egg yolk in a natural way. With a general increase in the health of farm animals, this "feed to food solution" will also have a positive impact on human nutrition directly via the food chain.
  • Natural ACE vital drinks Bread, pastry and pasta additive> Seasoning (liquid seasoning from extract, seasoning from powder material) , as a substitute for salt + pepper, especially for fatty meat products and in fat soups, "sea curry"> marine flavor note when smoking goods such as fish and meat with seaweed tea (gastric, intestinal and health-promoting, scientifically proven)> sea flower salt pastilles, alone or in combination with chlorella and / or sea buckthorn capsules for oral use (extract and powder) powder for oral use > Marine natural flavoring
  • Natural antioxidant or natural preservative or flavor enhancer in particular in the production of meat and sausages or in the manufacture of canned fish. preservation of meat or fish. Production of medicinal products such as medicinal plasters and medicinal packs, whereby the f seaweed packs, such as the type of mud packs, etc., are used or packs
  • Manufacturing wound dressings using natural bioactive ingredients such as high-quality chlorophyll as a natural deodorant (since the development of decomposing bacteria in seaweed inhibited or prevented) Chlorophyll and its descendants as a fine chemical to be isolated can be used as a dye, in products such as lollipops (here combinable with sea buckthorn), powder, soaps, sprays.
  • Marine biopolymer in new natural fiber composites e.g. in the packaging industry through the combination of seagrass powder ( ⁇ 200 ⁇ m) and polyurethane (PUR) or for the production of molded parts from PUR recycled materials marine biopolymer in new natural fiber composites, e.g. for the production of anti-allergic bed fillings and upholstery materials through the combination of seagrass powder ( ⁇ 200 ⁇ m) and polyurethane (PUR)
  • Carrier since the ion channels on the membranes of the cells in the seaweed are suitable as drug targets, and drug, since new, highly specialized agents are only formed in the seaweed.
  • sea flower thalasso salt peeling preferably seaweed micropowder or seaweed halophyte micropowder
  • sea buckthorn has its origin in the coastal regions of Eastern Europe (preferably the seagrass extracts or the seagrass halophyte extracts)> Production of a Thalasso vital bath (preferably the seagrass -Extracts or the seagrass halophyte extracts)> Production of face masks (preferably seagrass micropowder or the seagrass halophyte micropowder)> Production of a sea flower bath in the manner of the "Haslauer tub" (preferably the dried seaweed whole plants or / and the dried ones Whole seaweed and halophyte plants)> Manufacture of bathing tablets (preferably seaweed micropowder and / or seaweed sea buckthorn powder)
  • a gel made from Spissum is outstandingly suitable due to the resins and waxes contained in seaweed for the production of care and impregnation creams for smooth and natural leather (see Example 13).
  • the active ingredient complexes according to the invention are also suitable for use in the paint industry in the production of high-quality natural paints.
  • the invention makes it possible to provide new products for soil remediation from waste material from previous special uses of the plants of the sea grass, from the specific species of a plant family, such as e.g. the Zosteraceae in a) areas with a lack of Ca and Mg b) areas with salt-tolerant vegetation during land reclamation or c) from species from different plant families in the Mediterranean, e.g. the Posidoniaceae family, and other plant families from Asia, Australia, Africa, North and South America, in combination with the Zosteraceae of the Baltic Sea
  • the features of the invention are evident from the claims as well as from the description, the individual features representing advantageous protective designs, individually or in groups in the form of combinations, for which protection is requested with this document.
  • the essence of the invention consists of a combination from known (extracts from seaweed plants) and new elements (spissum extracts, micronization processes by air jet grinding), which mutually influence each other and, in their new overall effect, result in a benefit in use and the desired success, which lies in the fact that the plant with all its information, this but in a highly concentrated form, can be introduced or an excellent homogeneity of the powder is achieved.
  • Example 1 Obtaining the Spissum Extracts a) Aqueous Spissum Extract
  • EXAMPLE 2 Obtaining the Plant Drug Powder: The plant drug powder is obtained by air jet grinding with an air jet mill from Jet Mill Inc./USA. Examples of composition and use
  • GCMS analyzes led to individually documented phenol derivatives, sugar alcohols, various plant acids such as rosmaric acid, palmitic acid, myristic acid, cinnamic acid derivatives and other previously unknown substances which are likely to be Glycosides and is later to be characterized and isolated.
  • the retention time, the name of the first substance from the hit list and the percentage correspondence with the reference mass spectrum of the library were given in each case (100% means a perfect match, but this can never be achieved in practice due to device-specific differences in the detectors). From approximately 85%, the structure may be the same.
  • EXAMPLE 7 The representation of the biomass of the seagrass powder in general results in a spectrum of vitamins, minerals and trace elements which is outstandingly suitable for nutritional purposes in a balanced ratio in comparison to various types of macroalgae.
  • the iodine content is very balanced, not as with some "algae" in the genera, for example Laminaria and Ulva, the food and health industry warns of its excessive consumption. Even in external applications, some macroalgae can lead to skin rashes in allergy sufferers due to the high iodine content. In Zostera marina the iodine content is 230-540 ⁇ g / lOOg; in the brown algae Laminaria digitata, however,> 500 mg / 100g.
  • Example 8 Vitamins contained in seaweed
  • Vitamins A B2, inositol and E (antioxidants) in particular stand up to a comparison with sea buckthorn, apples and black currants which are rich in vitamins.
  • Seaweed can compete with sea buckthorn with a high VIT E content, and has at least as much VIT A content as apples and twice as much VIT A as black currants.
  • Table 4 Vitamin A, C, E content (mg / 100g) of Zostera marina (average values) and various types of fruit
  • Example 9 Elements contained in seaweed: Selenium, magnesium, calcium, potassium, sodium, iron and others were analyzed (Table 5).
  • Example 10 Production of a special extract from sea grass. Zostera marina, and sea buckthorn, Hippoyhae rhamnoides.
  • chlorophyll PUFAs (polyunsaturated fatty acids), dietary fibers, which, with their smell and taste, also stand out positively from the side effects and side effects that are unpleasant for algae.
  • Omega 3 fatty acids, omega 6 fatty acids, high quality chlorophyll and others to isolate individual ingredients can be obtained as fine chemicals, for which there is a great need, from seaweed, since seaweed is a "biomass collector in the Baltic Sea” and generally 'Thytomass storage' represents the oceans (K. Dier involved: Vegetation Norddeuropas, UTB Ulmer Verlag, 1996, pp. 221-222). Chlorophyll and other ingredients to be extracted, cellulose and others, are then to be used as fine chemicals for the chemical industry.
  • the gel made with Spissum from Zostera marina is excellent in its pure form or as an additive as a care and impregnation cream for smooth and natural leather (shoes, handbags, etc.).
  • the protection factor it contains has three effects on the leather: it forms a film that prevents the penetration of Schmitz. It effectively protects the leather from moisture. It maintains the leather with a long-lasting shine, without prior polishing.
  • seaweed thick extract is very suitable for the production of medicinal plasters, since the antimicrobial effects are exploited. This does not result in local pain therapy with plant extracts from cayenne pepper and arnica flowers, as in the case of heat plasters (for example from Beiersdorf), in which skin reddening, irritation and the like due to the allergenic substances from the daisy arnica or pepper. the like. Extracts from seaweed are not allergenic, as extensive dermatological studies have confirmed.

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Abstract

L'invention concerne des complexes de substances actives provenant de plantes de la famille du varech, obtenus par préparation d'extrait de spissum à partir de ces plantes ou par transformation des plantes par broyage au jet d'air, de manière à obtenir une poudre médicamenteuse végétale. Les complexes de substances actives peuvent être utilisés comme produits alimentaires, compléments alimentaires ou comme produits pharmaceutiques ou comme médicaments et, également, comme matériaux de construction ou d'emballage.
EP05716999A 2004-03-10 2005-03-10 Complexes de substances actives provenant de plantes de la famille du varech, en particulier de la famille zosteraceae, son procede de production et son utilisation Withdrawn EP1742649A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004012455A DE102004012455A1 (de) 2004-03-10 2004-03-10 Wirkstoffkomplexe aus Pflanzen der Familie Zosteraceae, Verfahren zu ihrer Herstellung und ihre Verwendung
DE102004023778A DE102004023778A1 (de) 2004-03-10 2004-05-07 Verwendung von Wirkstoffkomplexen aus Pflanzen der Familie Zosteraceae
PCT/EP2005/051100 WO2005087243A1 (fr) 2004-03-10 2005-03-10 Complexes de substances actives provenant de plantes de la famille du varech, en particulier de la famille zosteraceae, son procede de production et son utilisation

Publications (1)

Publication Number Publication Date
EP1742649A1 true EP1742649A1 (fr) 2007-01-17

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EP05716999A Withdrawn EP1742649A1 (fr) 2004-03-10 2005-03-10 Complexes de substances actives provenant de plantes de la famille du varech, en particulier de la famille zosteraceae, son procede de production et son utilisation

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EP (1) EP1742649A1 (fr)
DE (1) DE102004023778A1 (fr)
WO (1) WO2005087243A1 (fr)

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DE102007032662A1 (de) * 2007-07-13 2009-01-22 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen enthaltend ein oder mehrere Apiogalacturonane oder einen oder mehrere Apiogalacturonane enthaltenden Extrakt aus Zostera marina und einen zusätzlichen Gehalt an einem oder mehreren Hydrokolloiden
DE102007032663A1 (de) * 2007-07-13 2009-01-15 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen enthaltend ein oder mehrere Apiogalacturonane oder einen oder mehrere Apiogalacturonane enthaltenden Extrakt aus Zostera marina und eine oder mehrere UV-Licht absorbierende Substanzen
DE102007032660A1 (de) * 2007-07-13 2009-01-15 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen enthaltend ein oder mehrere Apiogalacturonane oder einen oder mehrere Apiogalacturonane enthaltenden Extrakt aus Zostera marina sowie einen oder mehrere ein- und/oder mehrwertige Alkohole

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