EP1704374A2 - Contenant de transport pour le maintien au froid de matieres congelees - Google Patents

Contenant de transport pour le maintien au froid de matieres congelees

Info

Publication number
EP1704374A2
EP1704374A2 EP05700741A EP05700741A EP1704374A2 EP 1704374 A2 EP1704374 A2 EP 1704374A2 EP 05700741 A EP05700741 A EP 05700741A EP 05700741 A EP05700741 A EP 05700741A EP 1704374 A2 EP1704374 A2 EP 1704374A2
Authority
EP
European Patent Office
Prior art keywords
refrigerant
transport container
container according
chamber
transport
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05700741A
Other languages
German (de)
English (en)
Inventor
Bernhard Sixt
Stefan Sixt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of EP1704374A2 publication Critical patent/EP1704374A2/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
    • F25D3/02—Devices using other cold materials; Devices using cold-storage bodies using ice, e.g. ice-boxes
    • F25D3/06—Movable containers
    • F25D3/08—Movable containers portable, i.e. adapted to be carried personally
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0263—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving, e.g. cool boxes, blood bags or "straws" for cryopreservation
    • A01N1/0273—Transport containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/04—Heat insulating devices, e.g. jackets for flasks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2201/00—Insulation
    • F25D2201/10—Insulation with respect to heat
    • F25D2201/14—Insulation with respect to heat using subatmospheric pressure
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
    • F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
    • F25D2303/083—Devices using cold storage material, i.e. ice or other freezable liquid using cold storage material disposed in closed wall forming part of a container for products to be cooled
    • F25D2303/0831—Devices using cold storage material, i.e. ice or other freezable liquid using cold storage material disposed in closed wall forming part of a container for products to be cooled the liquid is disposed in the space between the walls of the container
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2303/00—Details of devices using other cold materials; Details of devices using cold-storage bodies
    • F25D2303/08—Devices using cold storage material, i.e. ice or other freezable liquid
    • F25D2303/085—Compositions of cold storage materials
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2331/00—Details or arrangements of other cooling or freezing apparatus not provided for in other groups of this subclass
    • F25D2331/80—Type of cooled receptacles
    • F25D2331/804—Boxes

Definitions

  • the invention relates to a transport container for keeping frozen goods, in particular frozen biological tissue samples or cell cultures, with insulation that encloses an isolation chamber, with an inner container that is removably arranged in the isolation chamber and that holds the frozen goods in a chamber. and with a refrigerant releasing cold by phase change.
  • a well-known measure for keeping a good cool is to put the good in an insulated container and thus protect it against the entry of heat.
  • a transport container in particular, there are limits to the insulation wall thickness and thus the insulation effect. It is therefore essential, especially with longer storage or transport times, to ensure that penetrating
  • Heat is compensated for by an appropriate refrigeration in order to avoid a damaging rise in temperature or even thawing of frozen goods.
  • ice water
  • dry ice carbon dioxide
  • liquid nitrogen liquid nitrogen
  • ice has a melting point of 0 ° C that is too high to be used to keep frozen food cool
  • sublimation temperature of solidified carbon dioxide and the boiling temperature of liquid nitrogen are significantly lower than the usual frozen food temperatures, so that additional measures such as avoiding excessive cooling of the frozen goods an insulating wall between the refrigerant and the material must be taken for correct temperature control.
  • the conversion into the gaseous phase takes place here, so that comparatively large gas volumes are obtained which have to be discharged to the outside. This leads to problems in closed rooms, which makes it difficult, for example, to transport an appropriate transport container in an aircraft.
  • the invention has for its object to provide a comparatively small and light and therefore handy transport container, with which the frozen goods can be kept safely at the intended cooling temperature in a simple manner for a predetermined transport period, without any gases being released and without Measures to prevent excessive hypothermia are required.
  • At least one cooling chamber for the goods and at least one refrigerant chamber separate from the cooling chamber are provided, which contains the refrigerant and is permanently hermetically sealed, in that a refrigerant with a solid / liquid phase transition in the temperature range from - 15 ° to -100X is provided and that the insulation is super insulation with a coefficient of thermal conductivity ⁇ ⁇ 0.01 W / m K.
  • Suitable refrigerants are mercury or organic substances or mixtures whose phase transition temperature is preferably between -30 ° and -85X. Solidified mercury has a melting point of approx. -39 ° C (at atmospheric pressure).
  • This temperature is very suitable for keeping biological material such as tissue samples or cell cultures, which are sent for example for the analysis of proteins and RNA for the diagnosis of disease states (cancer), and excludes damage from hypothermia from the outset.
  • Another advantage is that when using the refrigerant there is no gas or steam and there is practically no change in volume during the phase transition.
  • the refrigerant remains inaccessible in the housing of the refrigerant chamber or in the inner container.
  • the mercury that has been liquefied (used) after transport can be prepared for a new cooling transport by freezing the removable refrigerant container or inner container through a phase reverse conversion liquid ⁇ solid, for example by immersing it in liquid nitrogen.
  • Avoiding dangers from toxic refrigerants such as mercury is also aimed at particularly simple manufacture and handling of the transport container and at adapting the cooling capacity to the transport route to be managed and thus the cooling period.
  • Figure 1 shows the transport container with essential parts in vertical section
  • Figure 2 shows the transport container in a horizontal cross section along line INI;
  • Figure 3 shows the inner container of Figure 1 in vertical section and on an enlarged scale;
  • FIG. 4 one of the two additional containers from FIG. 1 - likewise in vertical section and on an enlarged scale;
  • FIG. 5 shows an insulating plug with corresponding dimensions for replacement with an additional container, in side view
  • FIG. 6 shows a modified inner container in a representation corresponding to FIG. 3;
  • FIG. 7 shows a section along line VII-VII in FIG. 6;
  • FIG. 8 shows an enlarged detail with the closed filling opening from FIG. 6;
  • FIG. 9 shows an additional container modified compared to FIG. 4.
  • Figure 10 shows an inner container similar to Figures 3 and 6 in another embodiment
  • Figure 11 is a horizontal section along line Xl-Xl in Figure 10;
  • Figure 12 shows an additional container similar to Figures 4 and 9 in a different embodiment
  • FIG. 13 shows a grinding plug in a representation comparable to FIG. 8;
  • FIG. 14 shows the stopper according to FIG. 13 after applying a coating
  • FIG. 15 the plug installed in the fill opening with external welding
  • FIG. 17 shows the plug installed without welding into the filling opening
  • Figure 18 shows the arrangement of Figure 17 after finishing
  • Figure 19 in axial section an inner container with additional jacket cooling by a higher melting refrigerant.
  • the transport container 1 is cylindrical. It comprises, in a coaxial arrangement, a likewise cylindrical inner container 2 as well as two likewise cylindrical additional containers 3, 4, which are arranged on the front side above or below the inner container 2 in an insulating chamber 5.
  • the insulating chamber 5 is formed by a thick-walled, cup-shaped insulation 6 with an internally stepped upper edge 7, which receives a correspondingly graduated thick-walled insulating closure 8 in the form of a lid, which closes the insulating chamber 5.
  • the insulation 6 is closely enclosed by a rigid protective tube 9, which is provided at both ends with an external thread, with which the overlapping thread edge 10 of a screw cap 11 or 12 is firmly screwed.
  • the insulation 6 and the insulating closure 8 consist of a high-quality thermal insulation material with a very low coefficient of thermal conductivity ⁇ of, for example, 0.002
  • This well-known thermal insulation material is also referred to as super insulation because of its excellent insulating effect.
  • the inner container 2 is shown in Figure 3. It consists of a hollow housing or cup part 13 and a screw cover 14 screwed to it.
  • a cup-shaped refrigerant chamber 15 and a central cooling chamber 16 are formed in the cup part 13, which is closed by means of the screw cover 14.
  • the cooling chamber 16 receives the goods 17 to be kept cool and transported, in the case shown a sample in a sample container 18, the upper end of which is closed by a closure part 19.
  • the refrigerant chamber 15 is with a
  • Refrigerant 15 ' for example mercury filled, which is shown frozen in the solid state.
  • the cup part 13 is provided centrally on its bottom with a filling opening 20 which has a thread into which an Allen screw plug 21 is screwed.
  • the screw plug 21 is dimensioned and screwed so far into the filling opening 20 that an outer bottom recess 22 is present on the cup part 13.
  • This bottom recess 22 receives a weld bead 23, which arises when the filler opening 20 is closed. Accordingly, the refrigerant chamber 15 is permanently hermetically sealed, so that there is no fear of refrigerant 15 'escaping.
  • the cup part 13 and the screw cap 14 are made of a high-strength material so that pressure and shock loads are absorbed without deformation and it is ensured that there is no damage and leakage of refrigerant (mercury) even in extreme situations such as a plane crash. comes.
  • Suitable materials for the inner container 2 are e.g. Stainless steel, titanium or titanium alloys (TiAI5Sn2), which not only have a high strength but are also comparatively light, which reduces the transport weight.
  • other materials such as aluminum or low-temperature plastic can also be used.
  • the additional containers 3 and 4 are likewise hollow-cylindrical with a refrigerant chamber 24 but without a cooling chamber.
  • the refrigerant chamber 24 is also filled with a refrigerant 24 ', and as in FIG. 3, the additional containers 3, 4 are each provided with a filling opening 25, a screw plug 26 and a welding bead 27 centrally on the bottom side.
  • the additional containers 3, 4 can also be made from the aforementioned materials.
  • FIG. 5 shows a cylindrical insulating plug 28 in the dimensions of the additional containers 3, 4. Such insulating plugs 28 can be inserted into the housing instead of the additional containers 3, 4
  • Cooling chamber 16 are inserted if, with a correspondingly short transport distance or transport duration, the refrigerant 15 'in the inner container 2 is already sufficient to keep the good 17 cool during the transport.
  • an inner container 30 is provided, which instead of the inner container
  • the inner container 30 is cylindrically shaped and has a central cylindrical cooling chamber 31 starting from its upper side, which is enclosed by an annular refrigerant chamber 32 at a distance from the wall.
  • This refrigerant chamber 32 ends at a distance from the wall from the upper end face and the tere end of the inner container 30.
  • the refrigerant chamber 32 is also filled with refrigerant 32 'here.
  • a filler opening 33 which tapers slightly conically to the refrigerant chamber 32 is formed in the upper end face of the inner container 30, as shown in particular in FIG.
  • the filling opening 33 was closed by means of a stopper 34, which can also be made of stainless steel or titanium. Above the stopper 34, the fill opening 33 is welded shut by means of a welding bead 35.
  • the conical stopper 34 can usefully be installed with a press fit by being shrunk with strong hypothermia before installation.
  • an annular seal 36 made of amalgam-forming metal such as e.g. Copper can also be installed. This leads to the formation of amalgam (Hg-Cu alloy), and it may be possible to do without welding by means of the welding bead 37.
  • Figure 9 shows an additional container 37, which can also be made of stainless steel or titanium.
  • This additional container 37 also has a refrigerant chamber 38 filled with refrigerant 38 ', a design corresponding to FIG. 4 or FIG. 8 being provided for filling and closing (not shown in FIG. 9).
  • the additional container 37 has on its upper end face a central, short threaded pin 39 which fits into a central internal threaded hole 40 on the underside of the inner container 30. Therefore, the additional container 37 can be firmly connected to the inner container 30 and thereby achieve a tight fit between the containers 30 and 37, which ensures good heat transfer.
  • Another additional container 37 can be connected in a corresponding manner on the top side to the inner container 30.
  • the internal thread 41 on the upper edge of the cooling chamber 31 is used for this purpose.
  • the axial length is such that a screw plug 42 for closing the cooling chamber 31 can be screwed in so far by means of an Allen key that the threaded pin 39 of the
  • FIG. 10 shows another inner container 44, which comprises a cylindrical block 45 made of stainless steel or titanium, into which a plurality of bores are made starting from the upper end face. 11, a central bore is provided along the cylinder axis, which is surrounded by an inner ring of coaxial holes, which an outer ring is surrounded by coaxial holes.
  • the central bore and the bores of the inner ring form cooling chambers 46, so that a total of seven sample containers 18 according to FIG. 3 can be accommodated.
  • the twelve bores of the outer ring form refrigerant chambers 47, each of which has a refrigerant charge 47 '. At its upper end, the refrigerant chambers 47 are closed by means of a stopper 48 which can be screwed in or inserted by means of heat shrinking and held with a press fit.
  • the cover ring 49 has an internal thread 50, into which a disk-shaped screw plug 51 is screwed with its external thread 52, which ends flush with the cover ring 49.
  • the screw stopper 51 which closes the cooling chambers 46, has on its upper side two pairs of diametrically opposed hole bores 53, offset by 90 ° to one another, for attaching a spanner when screwing in or unscrewing.
  • the cover ring 49 has two diametrically opposite grooves 54, the two parallel
  • an additional container 55 is also provided in the form of a cylinder block 56 which, like the cylinder block 45, has an outer ring and an inner ring of holes, but no central hole.
  • both rings of bores form refrigerant chambers 57, which hold a refrigerant charge 57 '.
  • the refrigerant chambers 57 are each at their upper ends by means of a nes stopper 58 which, like the stopper 48 in FIG. 10, can be screwed in or attached with a press fit by means of cold shrinking.
  • the cylinder block 56 is provided on the upper side with a central threaded pin 59 for connection to the inner container 44 according to FIG. 10. Accordingly, the cylinder block 45 has a central threaded bore 60 on the underside. A corresponding threaded bore 61 is provided centrally on the top of the screw plug 51, so that an additional container 55 according to FIG. 12 can be connected to both ends of the inner container 44.
  • FIG. 13 shows, in an enlarged representation corresponding to FIG. 8, another conical stopper 62 for closing the conical filling opening 33, however, before it is inserted.
  • the plug 62 has a shaft-shaped projection 63, which serves to rotate the conical plug 62 and to grind it into the filling opening 33. After this plug 62 has been fitted in, it is provided with an electrolytic coating 64 made of amalgam-forming metal, as shown in FIG. 14.
  • the plug 62 with the coating 64 is now installed in the filling opening 33, expediently by means of heat shrinkage, so that it is held in the filling opening 33 with a press fit.
  • Two installation variants are preferably considered for this: According to FIG. 15, the plug 62 is arranged sunk in the fill opening 33 in accordance with the selected dimensions, whereupon additional welding is carried out by means of the welding bead 65.
  • the stopper 62 and the protruding weld bead 65 are then provided with a smooth processing surface 66 which is flush with the surface 68 of the housing or inner container 30 having the refrigerant chamber 32, as shown in FIG. 16.
  • the plug 62 completely fills the filling opening 33.
  • the protruding part of the plug 62 and in particular the entire shaft-shaped extension 63 are removed except for a processing surface 67 which, according to FIG. 18, is flush with the surface 68 of the housing or inner container 30 accommodating the refrigerant chamber 32.
  • the inner container 70 according to FIG. 19 largely corresponds to the inner container 2 shown in FIG. 3.
  • the cylindrically shaped inner container 70 has a refrigerant chamber 71 which is filled with the refrigerant 71 '.
  • An inner wall 72 and an outer wall 73 delimit the refrigerant chamber 71, which was filled with refrigerant 71 'and hermetically sealed in the manner already described above, which is not shown in FIG. 19.
  • the inner wall 72 encloses a cooling chamber 74, which is provided for receiving the sample.
  • An inner insulation 75 again designed as super insulation, surrounds the refrigerant chamber 71. This inner insulation 75 is enclosed by an essentially cylindrical wall 76.
  • the upper end of the cooling chamber 74 is in turn closed by a cover 77, not shown in section, which comprises a stopper screwed into the upper end of the inner wall 72 and a cover plate with an insulating effect.
  • the inner container 70 could already be used in the embodiment described so far if no increased refrigeration capacity is required due to the short transport duration and storage time.
  • the special feature of the inner container 70 is that it has a jacket chamber 78 which surrounds the wall 76 and which contains a refrigerant 78 'which melts more than the refrigerant 71' and has a melting point in the range from 0 ° to -15 ° C and has a jacket wall 79 is enclosed.
  • An insulating jacket 78 which surrounds the wall 76 and which contains a refrigerant 78 'which melts more than the refrigerant 71' and has a melting point in the range from 0 ° to -15 ° C and has a jacket wall 79 is enclosed.
  • the insulating jacket 80 with an outer container wall 81 encloses the jacket chamber 78.
  • the insulating jacket 80 again designed as superinsulation, is made in two parts with a cup-shaped bottom jacket part 82 and an inverted cup-shaped lid jacket part 83, so that the lid jacket part 83 can be removed, around the lid 77 and thus the cooling chamber 74 accessible.
  • the base casing part 82 and cover casing part 83 abut one another on the end face.
  • a narrow inner step ring 84 is provided on the base casing part 82 and a narrow outer step ring 85 on the cover casing part 2, which overlaps the inner step ring 84. This will increase the penetration of heat into the
  • refrigerant 71 'and 78' provided according to FIG. 19 has the advantage that the required amount of refrigerant 71 ', as a rule is more or less toxic and therefore critical, can be reduced and a less toxic or even non-toxic refrigerant (e.g. water or brine) that melts / solidifies at a slightly higher temperature in the range of 0 to 15 ° C can be used.
  • non-toxic refrigerant e.g. water or brine
  • the transport container 1 is used, for example, to transport one or more frozen tissue samples from one place to another, where stationary cooling devices for deep-freezing are present.
  • the sending process is therefore an intermediate link in a cold chain.
  • the delivery can take place by means of courier services which also transport to distant locations
  • the shipper first provides for deep cooling of the inner container 2, 30, 44, 70 and the additional container 3, 4, 37, 55 with liquid nitrogen with complete consolidation of the refrigerant charge 15 ', 24', 32 ', 38', 47 ', 57 ', 71', 78 '. Then the sample 17 placed in the sample container 18 is inserted into the cooling chamber 16, 31, 46, 74 and this is closed with the screw cap 14, 77 or the screw plug 42, 51. Now the inner container 2, 30, 44, 70 and possibly the additional container 3, 4; 37, 55 inserted into the insulation 6, in the case of the inner container 30,
  • the additional containers 37, 55, insofar as they are required, for example, for a long transport route for increased cooling capacity, are first screwed tightly to the inner container 30, 44.
  • the insulating cover 8 is placed thereon and the screw cover 11 is firmly screwed on, whereupon the transport container 1 is dispatched as soon as possible.
  • the receiver opens the transport container 1 and removes the sample container 18 with the sample 17 in the reverse order.
  • the receiver expediently measures the temperature in the insulation chamber 5 of the insulation 6 or in the cooling chamber 16, 31, 46, 74, which must be approximately ⁇ 40 ° C., for example, according to the melting point of the refrigerant. If this is not the case, it is clear that the cooling capacity of the refrigerant charge 15 ', 24', 32 ', 38', 47 ', 57', 71 ', 78' due to a massive exceeding of the transport time was not sufficient, so that the sample 17 may have been damaged and must then be discarded.
  • a transport container 1 provided with a 5 cm thick superinsulation according to the above information has, for example, an outer diameter of 24 cm and a length of 24 cm and is therefore handy and ideally suited for courier delivery.

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Thermal Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Combustion & Propulsion (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Packages (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention concerne un contenant de transport servant à l'expédition de matières congelées, notamment d'échantillons tissulaires biologiques, et comprenant une isolation en forme de chemise (superisolation) ainsi qu'un contenant intérieur extractible (44). Ce contenant intérieur extractible contient au moins une chambre à réfrigérant (47) remplie d'un réfrigérant (47'), ainsi qu'au moins une chambre de réfrigération (46) à l'intérieur de la chambre à réfrigérant (47). Le réfrigérant, par exemple du mercure ayant une température de fusion d'environ -39 °C, est enfermé hermétiquement et durablement dans la chambre à réfrigérant (47) et est solidifié avant l'expédition par surgélation, au moyen d'azote liquide par exemple. La chambre de réfrigération (46), et donc l'échantillon, sont maintenus à cette valeur de température pendant l'expédition alors que le réfrigérant, le mercure par exemple, fond lentement.
EP05700741A 2004-01-08 2005-01-07 Contenant de transport pour le maintien au froid de matieres congelees Withdrawn EP1704374A2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004001351 2004-01-08
DE102004032840 2004-07-06
PCT/EP2005/000086 WO2005066559A2 (fr) 2004-01-08 2005-01-07 Contenant de transport pour le maintien au froid de matieres congelees

Publications (1)

Publication Number Publication Date
EP1704374A2 true EP1704374A2 (fr) 2006-09-27

Family

ID=34751375

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05700741A Withdrawn EP1704374A2 (fr) 2004-01-08 2005-01-07 Contenant de transport pour le maintien au froid de matieres congelees

Country Status (6)

Country Link
US (1) US20070210090A1 (fr)
EP (1) EP1704374A2 (fr)
JP (1) JP4680935B2 (fr)
CN (1) CN100594347C (fr)
DE (1) DE112005000154A5 (fr)
WO (1) WO2005066559A2 (fr)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006032435A1 (de) * 2006-07-13 2008-01-17 Sixt, Bernhard, Dr. Transportbehälter zur Kühlhaltung von gefrorenem Gut
KR101486407B1 (ko) * 2006-07-28 2015-01-26 마퍼 리쏘그라피 아이피 비.브이. 리소그래피 시스템, 방열 방법 및 프레임
US7908870B2 (en) * 2007-05-04 2011-03-22 Entropy Solutions, Inc. Package having phase change materials and method of use in transport of temperature sensitive payload
US8887944B2 (en) 2007-12-11 2014-11-18 Tokitae Llc Temperature-stabilized storage systems configured for storage and stabilization of modular units
US8211516B2 (en) 2008-05-13 2012-07-03 Tokitae Llc Multi-layer insulation composite material including bandgap material, storage container using same, and related methods
US9174791B2 (en) 2007-12-11 2015-11-03 Tokitae Llc Temperature-stabilized storage systems
US20090145912A1 (en) * 2007-12-11 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Temperature-stabilized storage containers
US9205969B2 (en) * 2007-12-11 2015-12-08 Tokitae Llc Temperature-stabilized storage systems
US8215835B2 (en) 2007-12-11 2012-07-10 Tokitae Llc Temperature-stabilized medicinal storage systems
US9140476B2 (en) 2007-12-11 2015-09-22 Tokitae Llc Temperature-controlled storage systems
US9139351B2 (en) 2007-12-11 2015-09-22 Tokitae Llc Temperature-stabilized storage systems with flexible connectors
US8485387B2 (en) 2008-05-13 2013-07-16 Tokitae Llc Storage container including multi-layer insulation composite material having bandgap material
US20110086417A1 (en) * 2008-05-21 2011-04-14 Barnet Liberman Apparatus and Method for Using a Brine Solution to Freeze Biopsy Material
US9447995B2 (en) 2010-02-08 2016-09-20 Tokitac LLC Temperature-stabilized storage systems with integral regulated cooling
US9372016B2 (en) 2013-05-31 2016-06-21 Tokitae Llc Temperature-stabilized storage systems with regulated cooling
DE102010028769A1 (de) 2010-05-07 2011-11-10 Pvt Probenverteiltechnik Gmbh System zum Transportieren von Behältern zwischen unterschiedlichen Stationen und Behälterträger
CN101849535B (zh) * 2010-05-24 2013-04-17 中国水产科学研究院黄海水产研究所 便携式鱼类精子冷冻降温仪
WO2011159934A2 (fr) * 2010-06-18 2011-12-22 Biocision, Inc. Dispositif régulateur de la vitesse de congélation de spécimens
US8439221B2 (en) 2010-11-15 2013-05-14 Troy M. Davis Beverage container with chill sleeve
CN102246743B (zh) * 2011-04-20 2013-07-10 中国人民解放军第三军医大学 生物组织冻存装置
EP2589967A1 (fr) 2011-11-04 2013-05-08 Roche Diagnostics GmbH Système de distribution d'échantillon de laboratoire et procédé correspondant de fonctionnement
EP2589968A1 (fr) 2011-11-04 2013-05-08 Roche Diagnostics GmbH Système de distribution d'échantillons de laboratoire, système de laboratoire et procédé de fonctionnement
EP2589966A1 (fr) 2011-11-04 2013-05-08 Roche Diagnostics GmbH Système de distribution d'échantillon de laboratoire et procédé correspondant de fonctionnement
CN103112661A (zh) * 2012-12-11 2013-05-22 樊荣 一种便携式冷藏桶
CN103190393B (zh) * 2013-04-09 2015-05-13 上海安久生物科技有限公司 一种生物样本玻璃化冷冻载体及其用途
US9956140B2 (en) 2013-05-16 2018-05-01 Sandy Wengreen Storage systems and methods for medicines
US9151531B2 (en) * 2013-05-16 2015-10-06 Sandy Wengreen Storage systems and methods for medicines
US10588820B2 (en) 2013-05-16 2020-03-17 Sandy Wengreen Storage systems and methods for medicines
US9707156B2 (en) 2013-05-16 2017-07-18 Sandy Wengreen Storage systems and methods for medicines
US20160262979A1 (en) * 2013-05-16 2016-09-15 Sandy Wengreen Storage systems and methods for medicines
US9913777B2 (en) 2013-05-16 2018-03-13 Sandy Wengreen Storage systems and methods for medicines
US9844782B2 (en) * 2013-06-21 2017-12-19 Coldblock Technologies Inc. Systems and methods for preparing samples for chemical analysis using a cooled digestion zone
CN103548815B (zh) * 2013-11-18 2015-06-10 王意 液氮直入式细胞程序降温盒
DE102014202838B3 (de) 2014-02-17 2014-11-06 Roche Pvt Gmbh Transportvorrichtung, Probenverteilungssystem und Laborautomatierungssystem
DE102014202843B3 (de) 2014-02-17 2014-11-06 Roche Pvt Gmbh Transportvorrichtung, Probenverteilungssystem und Laborautomatisierungssystem
CN103848101A (zh) * 2014-03-14 2014-06-11 杜海兵 医药冷链箱
EP2927695B1 (fr) 2014-03-31 2018-08-22 Roche Diagniostics GmbH Système de distribution d'échantillons et système d'automatisation de laboratoire
EP2927168A1 (fr) * 2014-03-31 2015-10-07 Roche Diagniostics GmbH Dispositif de transport, système de distribution d'échantillons et système d'automatisation de laboratoire
EP2927625A1 (fr) 2014-03-31 2015-10-07 Roche Diagniostics GmbH Système de distribution d'échantillons et système d'automatisation de laboratoire
EP2927167B1 (fr) 2014-03-31 2018-04-18 F. Hoffmann-La Roche AG Dispositif d'envoi, système de distribution d'échantillons et système d'automatisation de laboratoire
EP2927163B1 (fr) 2014-03-31 2018-02-28 Roche Diagnostics GmbH Dispositif de transport vertical, système de distribution d'échantillons et système d'automatisation de laboratoire
EP3145826B1 (fr) * 2014-06-11 2023-09-06 Rmb Products Inc. Contenant de fluide rigide adapté aux changements de phase avec des évidements d'assistance de manipulation
EP2957914B1 (fr) 2014-06-17 2018-01-03 Roche Diagnostics GmbH Système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
FR3023714A1 (fr) * 2014-07-18 2016-01-22 Lab Francais Du Fractionnement Emballage de medicament de therapie innovante
EP2977766A1 (fr) 2014-07-24 2016-01-27 Roche Diagniostics GmbH Système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP2995580A1 (fr) 2014-09-09 2016-03-16 Roche Diagniostics GmbH Système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP2995960B1 (fr) 2014-09-09 2020-07-15 Roche Diagniostics GmbH Système de distribution d'échantillons de laboratoire et procédé d'étalonnage de capteurs magnétiques
US9952242B2 (en) 2014-09-12 2018-04-24 Roche Diagnostics Operations, Inc. Laboratory sample distribution system and laboratory automation system
EP2995958A1 (fr) 2014-09-15 2016-03-16 Roche Diagniostics GmbH Procédé pour faire fonctionner un système de réseau de distribution d'échantillons de laboratoire, système de distribution d' échantillons de laboratoire et système d'automatisation de laboratoire
EP3006943B1 (fr) 2014-10-07 2020-04-22 Roche Diagniostics GmbH Module pour système de distribution d'échantillons de laboratoire, système de distribution d'échantillons et système d'automatisation de laboratoire
EP3016116A1 (fr) 2014-11-03 2016-05-04 Roche Diagniostics GmbH Dispositif de carte de circuit imprimé, bobine pour système de distribution d'échantillons de laboratoire, système de distribution d'échantillons et système d'automatisation de laboratoire
EP3070479B1 (fr) 2015-03-16 2019-07-03 Roche Diagniostics GmbH Support de transport, système de distribution de marchandises de laboratoire et système d'automatisation de laboratoire
EP3073270B1 (fr) 2015-03-23 2019-05-29 Roche Diagniostics GmbH Système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3095739A1 (fr) 2015-05-22 2016-11-23 Roche Diagniostics GmbH Procédé de fonctionnement d'un système de distribution d'échantillons de laboratoire, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3096145B1 (fr) 2015-05-22 2019-09-04 Roche Diagniostics GmbH Procédé d'exploitation d'un système d'automatisation de laboratoire et système d'automatisation de laboratoire
EP3096146A1 (fr) 2015-05-22 2016-11-23 Roche Diagniostics GmbH Procédé de fonctionnement d'un système de distribution d'échantillons de laboratoire, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3112874A1 (fr) 2015-07-02 2017-01-04 Roche Diagnostics GmbH Module de stockage, procédé d'exploitation d'un système d'automatisation de laboratoire et système d'automatisation de laboratoire
EP3121603A1 (fr) 2015-07-22 2017-01-25 Roche Diagnostics GmbH Support de récipient d'échantillon, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
JP6836235B2 (ja) * 2015-08-11 2021-02-24 株式会社ジェイ・エム・エス 細胞搬送用容器
EP3139175B1 (fr) 2015-09-01 2021-12-15 Roche Diagnostics GmbH Système de distribution d'une cargaison de laboratoire, système d'automatisation de laboratoire et procédé de fonctionnement d'un système de distribution de cargaison de laboratoire
EP3153867B1 (fr) 2015-10-06 2018-11-14 Roche Diagniostics GmbH Système d'automatisation de laboratoire, procédé associé et système de distribution d'échantillons de laboratoire
EP3153866A1 (fr) 2015-10-06 2017-04-12 Roche Diagnostics GmbH Procédé de détermination d'une position de transfert intercellulaire et système d'automatisation de laboratoire
WO2017062692A1 (fr) 2015-10-06 2017-04-13 Cold Chain Technologies,Inc. Système d'expédition isolé thermiquement pour charge utile de taille palette, procédés de fabrication et d'utilisation associés et kit d'utilisation à cet effet
EP3156352B1 (fr) 2015-10-13 2019-02-27 Roche Diagniostics GmbH Système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3156353B1 (fr) 2015-10-14 2019-04-03 Roche Diagniostics GmbH Support de rotation d'un support de récipient d'échantillon, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
DE202016001097U1 (de) * 2016-01-28 2017-05-02 Va-Q-Tec Ag Transportbehältersystem
EP3211429A1 (fr) 2016-02-26 2017-08-30 Roche Diagnostics GmbH Dispositif de transport présentant une surface d'entraînement en mosaïque
EP3211430A1 (fr) 2016-02-26 2017-08-30 Roche Diagnostics GmbH Dispositif de transport de modules dotés d'une plaque de base
EP3211428A1 (fr) 2016-02-26 2017-08-30 Roche Diagnostics GmbH Unité de dispositif de transport pour un système de distribution d'échantillons de laboratoire
JP6708787B2 (ja) 2016-06-03 2020-06-10 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ラボラトリ試料分配システム及びラボラトリ自動化システム
EP3255519B1 (fr) 2016-06-09 2019-02-20 Roche Diagniostics GmbH Système de distribution d'échantillons de laboratoire et procédé d'exploitation d'un tel système
EP3260867A1 (fr) 2016-06-21 2017-12-27 Roche Diagnostics GmbH Procédé de détermination d'une position de transfert et système d'automatisation de laboratoire
MX2016008614A (es) * 2016-06-29 2017-12-28 Univ Nacional Autónoma De Mexico Dispositivo para la proteccion termica y transporte de biomacromoleculas.
CN109564232B (zh) 2016-08-04 2022-08-02 豪夫迈·罗氏有限公司 实验室样品分配系统和实验室自动化系统
USD804807S1 (en) 2016-09-22 2017-12-12 Sandy Wengreen Insulated container
EP3330717B1 (fr) 2016-12-01 2022-04-06 Roche Diagnostics GmbH Système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
CN106966060A (zh) * 2016-12-29 2017-07-21 浙江工商大学 一种冷藏式快递箱结构
EP3343232B1 (fr) 2016-12-29 2021-09-15 Roche Diagnostics GmbH Système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3355065B1 (fr) 2017-01-31 2021-08-18 Roche Diagnostics GmbH Système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3357842B1 (fr) 2017-02-03 2022-03-23 Roche Diagnostics GmbH Système d'automatisation de laboratoire
JP6881710B2 (ja) * 2017-03-28 2021-06-02 国立研究開発法人宇宙航空研究開発機構 断熱容器及びこれを用いた保温保冷装置
EP3410123B1 (fr) 2017-06-02 2023-09-20 Roche Diagnostics GmbH Procédé de fonctionnement d'un système de distribution d'échantillons de laboratoire, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3428653B1 (fr) 2017-07-13 2021-09-15 Roche Diagnostics GmbH Procédé de fonctionnement d'un système de distribution d'échantillon de laboratoire, système de distribution d'échantillon de laboratoire, et système d'automation de laboratoire
EP3456415B1 (fr) 2017-09-13 2021-10-20 Roche Diagnostics GmbH Support de récipient d'échantillon, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3457144B1 (fr) 2017-09-13 2021-10-20 Roche Diagnostics GmbH Support de récipient d'échantillon, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3537159B1 (fr) 2018-03-07 2022-08-31 Roche Diagnostics GmbH Procédé de fonctionnement d'un système de distribution d'échantillons de laboratoire, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
EP3540443B1 (fr) 2018-03-16 2023-08-30 Roche Diagnostics GmbH Système de laboratoire, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
US10722427B2 (en) 2018-03-29 2020-07-28 Simon Charles Cantor Hermetically sealable case for medical device and medicine
CN109160083A (zh) * 2018-09-27 2019-01-08 佛山科学技术学院 一种实验样品运输保存装置
KR200491161Y1 (ko) 2018-12-14 2020-04-24 대한민국 정액 스트로 동결용 액체질소 하우징
GB201917625D0 (en) * 2019-12-03 2020-01-15 Asymptote Ltd Container sterilising apparatus and method
US20210315201A1 (en) * 2020-04-08 2021-10-14 Biolife Solutions, Inc. Shock absorbing device to protect cryopreserved biological material
CN112167242B (zh) * 2020-09-24 2022-03-25 清华大学 一种基于多层相变材料的无主动冷却低温储运装置
WO2022094714A1 (fr) * 2020-11-05 2022-05-12 Acorn Biolabs, Inc. Système à température régulée pour la collecte et/ou le transport d'un matériau vivant et/ou sensible à la température
US11747356B2 (en) 2020-12-21 2023-09-05 Roche Diagnostics Operations, Inc. Support element for a modular transport plane, modular transport plane, and laboratory distribution system
KR102276406B1 (ko) * 2020-12-23 2021-07-12 천성태 검체 앰플 보관장치
US11602486B2 (en) * 2021-06-29 2023-03-14 Daniel Singh Device for chilling insulin in a travel mug
DE102022212394A1 (de) 2022-11-21 2024-05-23 dot.COOL Group Inc. Vakuumbehälter, verfahren zu seiner herstellung und evakuierungsmodul

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US52269A (en) * 1866-01-30 Improvement in bottle-stoppers
US1771186A (en) * 1928-06-20 1930-07-22 Mock Hugo Serving element for electric refrigerators
GB1004791A (en) * 1963-06-19 1965-09-15 Salterpak Ltd Improvements relating to thermally-insulated cases
US3858410A (en) * 1973-09-24 1975-01-07 Daniel H Drake Dental material mixing holder and cooler
US5355684A (en) * 1992-04-30 1994-10-18 Guice Walter L Cryogenic shipment or storage system for biological materials
AU7720596A (en) * 1995-11-09 1997-05-29 Aspen Systems, Inc. Flexible aerogel superinsulation and its manufacture
US5895561A (en) * 1996-01-17 1999-04-20 Kennecott Utah Copper Corporation Method of sealing cooling blocks using electrodeposited metal
JP2710606B2 (ja) * 1996-02-29 1998-02-10 耀明 蔡 冷却コップの冷却保持媒介剤
EP0922186B1 (fr) * 1996-08-30 2000-06-07 Triple CCC CC Boite pour flacon ou ampoule
NL1005375C1 (nl) * 1997-02-26 1998-08-28 Kombo Publishing B V Schaal voor het presenteren van voedingsmiddelen.
US5934099A (en) * 1997-07-28 1999-08-10 Tcp/Reliable Inc. Temperature controlled container
US6032481A (en) * 1997-08-26 2000-03-07 Mosby; Sharon D. Thermoregulating container
US6209343B1 (en) * 1998-09-29 2001-04-03 Life Science Holdings, Inc. Portable apparatus for storing and/or transporting biological samples, tissues and/or organs
US6119465A (en) * 1999-02-10 2000-09-19 Mullens; Patrick L. Shipping container for storing materials at cryogenic temperatures
US6446461B1 (en) * 2001-02-20 2002-09-10 David L. Williams, Jr. Beverage cooler
FR2840289A1 (fr) * 2002-05-29 2003-12-05 Centre Nat Rech Scient Caisse de conditionnement de produits biologiques et analogues

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2005066559A3 *

Also Published As

Publication number Publication date
WO2005066559A2 (fr) 2005-07-21
JP4680935B2 (ja) 2011-05-11
DE112005000154A5 (de) 2007-06-21
JP2007523013A (ja) 2007-08-16
CN100594347C (zh) 2010-03-17
CN101124444A (zh) 2008-02-13
US20070210090A1 (en) 2007-09-13
WO2005066559A3 (fr) 2005-11-10

Similar Documents

Publication Publication Date Title
WO2005066559A2 (fr) Contenant de transport pour le maintien au froid de matieres congelees
EP2041502B1 (fr) Récipient de transport permettant la conservation au froid de produits congelés
EP3448154B1 (fr) Dispositif et procédé de surveillance de la température d'un échantillon biologique cryoconservé
DE3234457C2 (de) Kühlbad zum raschen Abkühlen von Proben, insbesondere zur Kryofixation biologischer Objekte für eine nachfolgende licht- oder elektronenoptische Untersuchung
EP2936010B1 (fr) Procédé de préconditionnement d'éléments d'accumulateur de chaleur latente
WO2017055280A1 (fr) Cellule de stockage à protection thermique d'une boîte de transport frigorifique
DE102012006743B4 (de) Isolierbehälter
DE202006004344U1 (de) Selbstkühlender Transportbehälter für den Versand von tiefgefrorenen Gewebeproben und anderen temperaturempfindlichen Gütern
WO2018015350A1 (fr) Contenant réfrigérant et procédé de transport d'échantillons cryogéniques
DE1918624B2 (de) Vorrichtung zur kontinuierlichen tiefkuehlung von objekten
EP2146162B1 (fr) Elément d'équilibrage des températures et procédé destiné au fonctionnement d'un récipient d'isolation
EP1359380A2 (fr) Récipient pour un liquide
EP3448152A1 (fr) Procédé et dispositif de surveillance de la température d'un échantillon biologique cryoconservé
DE10056131A1 (de) Kühlvorrichtung für Zellen enthaltend Flüssigkeitsproben
DE10304122B4 (de) Mobiler Kühlbehälter, insbesondere für den Transport von tiefgefrorenen Lebensmitteln
DE2739796A1 (de) Einrichtung zur gefriertrocknung und gegebenenfalls kunstharz-impraegnation kleiner biologischer objekte fuer die elektronenmikroskopische untersuchung
EP2087303B1 (fr) Dispositif réfrigérant d'eau potable intégré dans un réfrigérateur
DE1751608A1 (de) Verfahren zur Container-Kuehlhaltung
DE3717053C2 (fr)
DE2335041A1 (de) Eishaube
DE102022004361A1 (de) Trinkgefäß mit integrierter Kühlung
DE202010009862U1 (de) Isolierbehälter
DE2926646A1 (de) Kryogengefaess
DE1501319B2 (de) Kryostat mit einem tiefsiedenden fluessigen kuehlmittel insbesondere zur kuehlung von supraleitungsspulen
DE1501319C (de) Kryostat mit einem tiefsiedenden flus sigen Kuhlmittel, insbesondere zur Kühlung von Supraleitungsspulen

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20060706

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
17Q First examination report despatched

Effective date: 20131204

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20140617