EP1504099A4 - Nouveaux acides nucleiques et polypeptides - Google Patents
Nouveaux acides nucleiques et polypeptidesInfo
- Publication number
- EP1504099A4 EP1504099A4 EP02805571A EP02805571A EP1504099A4 EP 1504099 A4 EP1504099 A4 EP 1504099A4 EP 02805571 A EP02805571 A EP 02805571A EP 02805571 A EP02805571 A EP 02805571A EP 1504099 A4 EP1504099 A4 EP 1504099A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- polypeptides
- nucleic acids
- novel nucleic
- novel
- acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Applications Claiming Priority (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US128558 | 1987-12-03 | ||
US33973901P | 2001-12-10 | 2001-12-10 | |
US339739P | 2001-12-10 | ||
US33945301P | 2001-12-11 | 2001-12-11 | |
US339453P | 2001-12-11 | ||
US36509102P | 2002-03-14 | 2002-03-14 | |
US36538402P | 2002-03-14 | 2002-03-14 | |
US365091P | 2002-03-14 | ||
US365384P | 2002-03-14 | ||
US37238102P | 2002-04-12 | 2002-04-12 | |
US37261502P | 2002-04-12 | 2002-04-12 | |
US372615P | 2002-04-12 | ||
US372381P | 2002-04-12 | ||
US10/128,558 US20040219521A1 (en) | 2000-01-21 | 2002-04-22 | Novel nucleic acids and polypeptides |
US37604502P | 2002-04-24 | 2002-04-24 | |
US376045P | 2002-04-24 | ||
PCT/US2002/039555 WO2003054152A2 (fr) | 2001-12-10 | 2002-12-10 | Nouveaux acides nucleiques et polypeptides |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1504099A2 EP1504099A2 (fr) | 2005-02-09 |
EP1504099A4 true EP1504099A4 (fr) | 2006-05-10 |
Family
ID=27574889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02805571A Withdrawn EP1504099A4 (fr) | 2001-12-10 | 2002-12-10 | Nouveaux acides nucleiques et polypeptides |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1504099A4 (fr) |
AU (1) | AU2002366951A1 (fr) |
CA (1) | CA2469941A1 (fr) |
WO (1) | WO2003054152A2 (fr) |
Families Citing this family (128)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE9315698U1 (de) * | 1993-10-14 | 1993-12-23 | Buechi Lab Tech | Verdampfer-Kolben für einen Rotationsverdampfer |
EP1434783A4 (fr) * | 2001-03-16 | 2006-06-07 | Lilly Co Eli | Proteines de mammiferes lp et reactifs associes |
EP1992643A3 (fr) | 2001-06-20 | 2008-12-10 | Genentech, Inc. | Compositions et procédés pour le traitement et le diagnostic d'une tumeur |
US20030068691A1 (en) * | 2001-07-16 | 2003-04-10 | Applera Corporation | Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof |
JP4208715B2 (ja) * | 2001-08-30 | 2009-01-14 | ヌヴェロ, インコーポレイテッド | 幹細胞増殖因子様ポリペプチドおよびポリヌクレオチドに関する方法および材料 |
CA2462790A1 (fr) | 2001-10-04 | 2003-04-10 | Immunex Corporation | Proteine de liaison ul16, la proteine 4 |
US7202056B2 (en) | 2002-03-28 | 2007-04-10 | Bristol-Myers Squibb Company | Polynucleotides encoding a human cell surface protein with immunoglobulin folds, BGS-19 |
WO2003091436A1 (fr) | 2002-04-26 | 2003-11-06 | Fujisawa Pharmaceutical Co., Ltd. | Nouvelle proteine 35kd |
WO2004005335A2 (fr) * | 2002-07-05 | 2004-01-15 | Borean Pharma A/S | Hormone de croissance multimerisee |
JP5401001B2 (ja) | 2002-09-11 | 2014-01-29 | ジェネンテック, インコーポレイテッド | 免疫関連疾患の治療のための新規組成物と方法 |
JP4679149B2 (ja) | 2002-09-30 | 2011-04-27 | オンコセラピー・サイエンス株式会社 | ヒト膵癌に関連する遺伝子およびポリペプチド |
PT2248899E (pt) | 2003-03-19 | 2015-09-23 | Biogen Ma Inc | Proteína de ligação do receptor nogo |
JP4632953B2 (ja) * | 2003-09-29 | 2011-02-16 | 中外製薬株式会社 | Nk細胞に発現するタンパク質 |
ATE423200T1 (de) * | 2003-10-30 | 2009-03-15 | Kazusa Dna Res Inst Foundation | Neues plexin-polypeptid, dieses codierende dna und verwendung davon |
KR101520209B1 (ko) | 2003-11-06 | 2015-05-13 | 시애틀 지네틱스, 인크. | 리간드에 접합될 수 있는 모노메틸발린 화합물 |
TW200536859A (en) * | 2004-01-27 | 2005-11-16 | Nuvelo Inc | Gastrointestinal proliferative factor and uses thereof |
GB0403491D0 (en) * | 2004-02-17 | 2004-03-24 | Univ Cambridge Tech | Polypeptides, methods and means |
US20050186577A1 (en) | 2004-02-20 | 2005-08-25 | Yixin Wang | Breast cancer prognostics |
ATE491043T1 (de) * | 2004-04-09 | 2010-12-15 | Us Gov Health & Human Serv | Diagnosegerät zur diagnose gutartiger gegenüber bösartigen schilddrüsenläsionen |
NZ551180A (en) | 2004-06-01 | 2009-10-30 | Genentech Inc | Antibody drug conjugates and methods |
ES2395094T3 (es) | 2004-06-24 | 2013-02-08 | Biogen Idec Ma Inc. | Tratamiento de afecciones que implican la desmielinización |
WO2006008294A2 (fr) * | 2004-07-23 | 2006-01-26 | Evotec Neurosciences Gmbh | Utilisation diagnostique et therapeutique du slim pour des maladies neurodegeneratives |
EP1791565B1 (fr) | 2004-09-23 | 2016-04-20 | Genentech, Inc. | Anticorps et conjugues produits avec de la cysteine |
US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
WO2006124667A2 (fr) | 2005-05-12 | 2006-11-23 | Zymogenetics, Inc. | Compositions et procedes permettant de moduler des reponses immunitaires |
MX2008000253A (es) | 2005-07-08 | 2008-04-02 | Biogen Idec Inc | Anticuerpos de sp35 y usos de los mismos. |
ES2543341T3 (es) | 2005-09-13 | 2015-08-18 | National Research Council Of Canada | Métodos y composiciones para modular la actividad de células tumorales |
GB0522113D0 (en) * | 2005-10-28 | 2005-12-07 | Ares Trading Sa | vWFA-domain containing proteins |
GB0525999D0 (en) * | 2005-12-21 | 2006-02-01 | Ares Trading Sa | Novel members of the kazal family of serine protease inhibitors |
GB0615287D0 (en) * | 2006-08-01 | 2006-09-06 | Ares Trading Sa | Integral membrane protein |
CA2665223A1 (fr) * | 2006-10-02 | 2008-05-29 | The Scripps Research Institute | Enzyme regulant les voies de signalisation des lipides d'ether |
GB0620735D0 (en) * | 2006-10-18 | 2006-11-29 | Ares Trading Sa | Proteins |
CA2691378A1 (fr) | 2007-07-02 | 2009-01-08 | Oncomed Pharmaceuticals, Inc. | Anticorps contre la r-spondine humaine et utilisation associee en vue de l'inhibition du signalement de beta-catenine et traitement du cancer |
GB0805159D0 (en) | 2008-03-19 | 2008-04-23 | Sancho Madrid David | Immune modulation via C-type lectin |
CA2697448C (fr) | 2007-08-30 | 2019-06-11 | The Burnet Institute | Marqueur de cellules dendritiques et son utilisation |
WO2009046407A2 (fr) * | 2007-10-04 | 2009-04-09 | Zymogenetics, Inc. | Zb7h6 membre de la famille b7 et compositions et procédés apparentés |
CN101918540B (zh) * | 2007-11-08 | 2016-05-11 | 比奥根Ma公司 | Lingo-4拮抗剂在治疗涉及脱髓鞘的疾患中的应用 |
SG10201402815VA (en) | 2008-04-09 | 2014-09-26 | Genentech Inc | Novel compositions and methods for the treatment of immune related diseases |
US20110110861A1 (en) * | 2008-05-13 | 2011-05-12 | Mireille Hanna Lahoud | Methods of Detecting Cells with a Disrupted Cell Membrane, Cells Infected with A Pathogen, Dying Cells or Dead Cells |
DK2982695T3 (da) | 2008-07-09 | 2019-05-13 | Biogen Ma Inc | Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf |
US8227417B2 (en) | 2008-07-25 | 2012-07-24 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | HMGN polypeptides as immune enhancers and HMGN antagonists as immune suppressants |
EP2412800A1 (fr) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Organoïde du foie, ses utilisations et son procédé de culture pour l'obtenir |
PL3441458T3 (pl) | 2009-02-03 | 2023-11-06 | Koninklijke Nederlandse Akademie Van Wetenschappen | Podłoże do hodowli nabłonkowych komórek macierzystych i organoidów zawierających wspomniane komórki macierzyste |
US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
EP2448966B1 (fr) | 2009-07-03 | 2018-11-14 | Avipep Pty Ltd | Immunoconjugués et leurs procédés de production |
WO2011004404A1 (fr) * | 2009-07-10 | 2011-01-13 | Decode Genetics Ehf | Variantes génétiques pour prédire le risque de glaucome |
JP2013504585A (ja) | 2009-09-09 | 2013-02-07 | セントローズ, エルエルシー | 細胞外標的化薬物複合体 |
ES2734886T3 (es) | 2009-11-24 | 2019-12-12 | Alethia Biotherapeutics Inc | Anticuerpos anti-clusterina y fragmentos de unión a antígeno y su uso para reducir el volumen tumoral |
CA2784610C (fr) | 2009-12-23 | 2020-07-14 | Avipep Pty Ltd | Immuno-conjugues et leurs methodes de production |
KR101738203B1 (ko) | 2010-04-15 | 2017-05-19 | 메디뮨 리미티드 | 피롤로벤조디아제핀 및 그의 컨주게이트 |
CA3220104A1 (fr) | 2010-06-08 | 2011-12-15 | Genentech, Inc. | Anticorps et conjugues modifies par la cysteine |
NZ607996A (en) | 2010-09-22 | 2014-07-25 | Alios Biopharma Inc | Substituted nucleotide analogs |
US20120121615A1 (en) | 2010-11-17 | 2012-05-17 | Flygare John A | Alaninyl maytansinol antibody conjugates |
WO2012142662A1 (fr) | 2011-04-21 | 2012-10-26 | Garvan Institute Of Medical Research | Molécules à domaine variable modifié et procédés de préparation et d'utilisation de celles-ci |
JP5987053B2 (ja) | 2011-05-12 | 2016-09-06 | ジェネンテック, インコーポレイテッド | フレームワークシグネチャーペプチドを用いて動物サンプルにおける治療抗体を検出するための多重反応モニタリングlc−ms/ms法 |
WO2013012747A1 (fr) | 2011-07-15 | 2013-01-24 | Oncomed Pharmaceuticals, Inc. | Agents de fixation aux protéines rspo et leurs utilisations |
EP2750713B1 (fr) | 2011-10-14 | 2015-09-16 | Spirogen Sàrl | Pyrrolobenzodiazépines et conjugués associés |
EP2794630A4 (fr) | 2011-12-22 | 2015-04-01 | Alios Biopharma Inc | Analogues de nucléotide phosphorothioate substitués |
CN104159611A (zh) | 2012-02-22 | 2014-11-19 | 阿莱斯亚生物疗法股份有限公司 | 共使用簇集蛋白抑制剂和egfr抑制剂以治疗癌症 |
WO2013130093A1 (fr) | 2012-03-02 | 2013-09-06 | Genentech, Inc. | Biomarqueurs pour un traitement à base de composés chimiothérapeutiques anti-tubuline |
CN104321333A (zh) | 2012-03-21 | 2015-01-28 | 沃泰克斯药物股份有限公司 | 硫代氨基磷酸酯核苷酸前药的固体形式 |
WO2013142157A1 (fr) | 2012-03-22 | 2013-09-26 | Alios Biopharma, Inc. | Combinaisons pharmaceutiques comprenant un analogue thionucléotidique |
WO2013173364A2 (fr) | 2012-05-14 | 2013-11-21 | Biogen Idec Ma Inc. | Antagonistes de lingo-2 pour le traitement d'affections impliquant des neurones moteurs |
JP6335896B2 (ja) | 2012-07-13 | 2018-05-30 | オンコメッド ファーマシューティカルズ インコーポレイテッド | Rspo3結合剤およびその使用法 |
SI2906253T1 (sl) | 2012-10-12 | 2018-11-30 | Adc Therapeutics Sa | Konjugati pirolobenzodiazepin-protitelo proti PSMA |
WO2014057120A1 (fr) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Conjugués anticorps - pyrrolobenzodiazépine |
HUE045435T2 (hu) | 2012-10-12 | 2019-12-30 | Medimmune Ltd | Pirrolobenzodiazepinek és konjugátumaik |
HUE042731T2 (hu) | 2012-10-12 | 2019-07-29 | Adc Therapeutics Sa | Pirrolobenzodiazepin-antitest konjugátumok |
ES2680153T3 (es) | 2012-10-12 | 2018-09-04 | Adc Therapeutics Sa | Conjugados de anticuerpos anti-PSMA-pirrolobenzodiazepinas |
BR112015008238A2 (pt) | 2012-10-12 | 2017-11-28 | Adc Therapeutics Sarl | conjugados de pirrolbenzodiazepina-anticorpo anti-cd22 |
AU2013328625B2 (en) | 2012-10-12 | 2016-12-15 | Adc Therapeutics Sa | Pyrrolobenzodiazepine-antibody conjugates |
JP6307519B2 (ja) | 2012-12-21 | 2018-04-04 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピンおよびその結合体 |
EA032986B1 (ru) | 2012-12-21 | 2019-08-30 | Медимьюн Лимитед | Пирролобензодиазепины |
CA2905181C (fr) | 2013-03-13 | 2020-06-02 | Medimmune Limited | Pyrrolobenzodiazepines et ses conjugues servant a fournir une therapie ciblee |
JP6340019B2 (ja) | 2013-03-13 | 2018-06-06 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピン及びそのコンジュゲート |
EA027910B1 (ru) | 2013-03-13 | 2017-09-29 | Медимьюн Лимитед | Пирролобензодиазепины и их конъюгаты |
KR20160030936A (ko) | 2013-07-16 | 2016-03-21 | 제넨테크, 인크. | Pd-1 축 결합 길항제 및 tigit 억제제를 사용한 암을 치료하는 방법 |
MX2016001862A (es) | 2013-08-12 | 2016-08-03 | Genentech Inc | Compuestos de conjugado anticuerpo-farmaco dimerico de 1-(clorometil)-2,3-dihidro-1h-benzo[e]indol, y metodos de uso y tratamiento. |
WO2015052534A1 (fr) | 2013-10-11 | 2015-04-16 | Spirogen Sàrl | Conjugués anticorps-pyrrolobenzodiazépine |
GB201317982D0 (en) | 2013-10-11 | 2013-11-27 | Spirogen Sarl | Pyrrolobenzodiazepines and conjugates thereof |
US9956299B2 (en) | 2013-10-11 | 2018-05-01 | Medimmune Limited | Pyrrolobenzodiazepine—antibody conjugates |
EP3054983B1 (fr) | 2013-10-11 | 2019-03-20 | Medimmune Limited | Conjugués anticorps-pyrrolobenzodiazépines |
JP6980384B2 (ja) | 2013-12-16 | 2021-12-15 | ジェネンテック, インコーポレイテッド | 1−(クロロメチル)−2,3−ジヒドロ−1h−ベンゾ[e]インドール二量体抗体−薬物コンジュゲート化合物、並びに使用及び処置の方法 |
RU2689388C1 (ru) | 2013-12-16 | 2019-05-28 | Дженентек, Инк. | Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами |
EP3082875B1 (fr) | 2013-12-16 | 2020-11-25 | Genentech, Inc. | Composés peptidomimétiques et conjugués anticorps-médicament de ceux-ci |
US10188746B2 (en) | 2014-09-10 | 2019-01-29 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
CA2957354A1 (fr) | 2014-09-12 | 2016-03-17 | Genentech, Inc. | Anticorps et conjugues modifies genetiquement avec de la cysteine |
GB201416112D0 (en) | 2014-09-12 | 2014-10-29 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
EP3191134B1 (fr) | 2014-09-12 | 2019-11-20 | Genentech, Inc. | Intermédiaires disulfure d'anthracycline, conjugué anticorps-médicaments et procédés |
US10064937B2 (en) | 2014-09-16 | 2018-09-04 | Oncomed Pharmaceuticals, Inc. | Treatment of dermal fibrosis |
MX2017003523A (es) | 2014-09-17 | 2017-11-08 | Genentech Inc | Pirrolobenzodiazepinas y conjugados de anticuerpo-disulfuro de las mismas. |
CN107148285B (zh) | 2014-11-25 | 2022-01-04 | Adc治疗股份有限公司 | 吡咯并苯并二氮杂䓬-抗体缀合物 |
EP3226909A1 (fr) | 2014-12-03 | 2017-10-11 | Genentech, Inc. | Composés d'amine quaternaire et conjugués anticorps-médicament de ceux-ci |
MX2017009038A (es) | 2015-01-08 | 2017-10-25 | Biogen Ma Inc | Antagonistas de proteina 1 de interacción con el receptor de nogo que contiene el dominio de inmunoglobulina y repeticiones ricas en leucina (lingo-1) y usos para el tratamiento de trastornos desmielinizantes. |
GB201506411D0 (en) | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
GB201506402D0 (en) | 2015-04-15 | 2015-05-27 | Berkel Patricius H C Van And Howard Philip W | Site-specific antibody-drug conjugates |
CR20220186A (es) | 2015-09-25 | 2022-07-07 | Genentech Inc | ANTICUERPOS ANTI-TIGIT Y MÉTODOS DE USO (divisional 2018-0225) |
MA43345A (fr) | 2015-10-02 | 2018-08-08 | Hoffmann La Roche | Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation |
MA43354A (fr) | 2015-10-16 | 2018-08-22 | Genentech Inc | Conjugués médicamenteux à pont disulfure encombré |
MA45326A (fr) | 2015-10-20 | 2018-08-29 | Genentech Inc | Conjugués calichéamicine-anticorps-médicament et procédés d'utilisation |
GB201601431D0 (en) | 2016-01-26 | 2016-03-09 | Medimmune Ltd | Pyrrolobenzodiazepines |
GB201602359D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
GB201602356D0 (en) | 2016-02-10 | 2016-03-23 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
JP6943872B2 (ja) | 2016-03-25 | 2021-10-06 | ジェネンテック, インコーポレイテッド | 多重全抗体及び抗体複合体化薬物定量化アッセイ |
GB201607478D0 (en) | 2016-04-29 | 2016-06-15 | Medimmune Ltd | Pyrrolobenzodiazepine Conjugates |
WO2017201449A1 (fr) | 2016-05-20 | 2017-11-23 | Genentech, Inc. | Conjugués anticorps-protac et procédés d'utilisation |
JP7022080B2 (ja) | 2016-05-27 | 2022-02-17 | ジェネンテック, インコーポレイテッド | 部位特異的抗体-薬物複合体の特徴付けのための生化学分析的方法 |
EP3464280B1 (fr) | 2016-06-06 | 2021-10-06 | F. Hoffmann-La Roche AG | Médicaments conjugués d'anticorps silvestrol et procédés d'utilisation |
WO2018031662A1 (fr) | 2016-08-11 | 2018-02-15 | Genentech, Inc. | Promédicaments de pyrrolobenzodiazépine et conjugués d'anticorps de ceux-ci |
CN110139674B (zh) | 2016-10-05 | 2023-05-16 | 豪夫迈·罗氏有限公司 | 制备抗体药物缀合物的方法 |
GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
WO2018115879A1 (fr) | 2016-12-21 | 2018-06-28 | Mereo Biopharma 3 Limited | Utilisation d'anticorps anti-sclérostine dans le traitement de l'ostéogenèse imparfaite |
JP6671555B2 (ja) | 2017-02-08 | 2020-03-25 | アーデーセー セラピューティクス ソシエテ アノニム | ピロロベンゾジアゼピン抗体複合体 |
GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
AU2018255876B2 (en) | 2017-04-18 | 2020-04-30 | Medimmune Limited | Pyrrolobenzodiazepine conjugates |
AU2018253948A1 (en) | 2017-04-20 | 2019-09-19 | Adc Therapeutics Sa | Combination therapy with an anti-AXL Antibody-Drug Conjugate |
MX2019015042A (es) | 2017-06-14 | 2020-08-06 | Adc Therapeutics Sa | Regimen de dosificacion. |
KR102270107B1 (ko) | 2017-08-18 | 2021-06-30 | 메디뮨 리미티드 | 피롤로벤조디아제핀 컨쥬게이트 |
CN111788208B (zh) | 2017-09-20 | 2023-11-24 | Ph制药有限公司 | 泰兰他汀类似物 |
GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
US11401339B2 (en) | 2018-08-23 | 2022-08-02 | Seagen Inc. | Anti-TIGIT antibodies |
GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
JP2022505450A (ja) | 2018-10-24 | 2022-01-14 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | コンジュゲート化された化学的分解誘導物質および使用方法 |
CN113227119A (zh) | 2018-12-10 | 2021-08-06 | 基因泰克公司 | 用于与含Fc的蛋白质进行位点特异性缀合的光交联肽 |
GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
GB2597532A (en) | 2020-07-28 | 2022-02-02 | Femtogenix Ltd | Cytotoxic compounds |
GB202211117D0 (en) * | 2022-07-29 | 2022-09-14 | Replay Holdings Llc | Compositions and methods for non-immunogenecity |
-
2002
- 2002-12-10 AU AU2002366951A patent/AU2002366951A1/en not_active Abandoned
- 2002-12-10 CA CA002469941A patent/CA2469941A1/fr not_active Abandoned
- 2002-12-10 EP EP02805571A patent/EP1504099A4/fr not_active Withdrawn
- 2002-12-10 WO PCT/US2002/039555 patent/WO2003054152A2/fr not_active Application Discontinuation
Non-Patent Citations (2)
Title |
---|
DATABASE EMBL [online] 22 December 1994 (1994-12-22), "Homo sapiens glutathione S-transferase theta 2 (GSTT2) mRNA, complete cds.", XP002357957, retrieved from EBI accession no. EM_PRO:HSGSTT2A Database accession no. L38503 * |
DATABASE UniProt [online] 1 April 1993 (1993-04-01), "Glutathione S-transferase theta 2 (EC 2.5.1.18) (GST class-theta 2).", XP002357958, retrieved from EBI accession no. UNIPROT:GSTT2_HUMAN Database accession no. P30712 * |
Also Published As
Publication number | Publication date |
---|---|
WO2003054152A2 (fr) | 2003-07-03 |
CA2469941A1 (fr) | 2003-07-03 |
WO2003054152A3 (fr) | 2004-12-16 |
EP1504099A2 (fr) | 2005-02-09 |
AU2002366951A1 (en) | 2003-07-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1504099A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
EP1381621A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
EP1432800A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
EP1470238A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
AU2001234944A8 (en) | Novel nucleic acids and polypeptides | |
EP1325120A4 (fr) | Acides nucleiques et polypeptides | |
EP1430112A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
EP1341804A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
AU2002368010A8 (en) | Novel nucleic acids and secreted polypeptides | |
EP1556490A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
AU2001233041A1 (en) | Novel nucleic acids and polypeptides | |
AU2001238347A1 (en) | Novel nucleic acids and polypeptides | |
AU2001233017A1 (en) | Novel nucleic acids and polypeptides | |
EP1368475A4 (fr) | Nouveaux acides nucleiques et nouveaux polypeptides | |
EP1276751A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
AU2002367815A8 (en) | Novel nucleic acids and secreted polypeptides | |
EP1341803A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
AU2002250419A1 (en) | Novel nucleic acids and polypeptides | |
AU2001263005A8 (en) | Novel nucleic acids and polypeptides | |
EP1268762A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
IL161765A0 (en) | P85-alpha nucleic acids, polypeptides and related methods | |
EP1274716A4 (fr) | Nouveaux acides nucleiques et nouveaux polypeptides | |
AU7005801A (en) | Gp354 nucleic acids and polypeptides | |
EP1370675A4 (fr) | Nouveaux acides nucleiques et polypeptides | |
EP1409523A4 (fr) | Acides nucleiques et polypeptides pancam |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20040705 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C07K 14/00 19950101ALI20051208BHEP Ipc: C12N 15/00 19800101AFI20051208BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20060328 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN |
|
18W | Application withdrawn |
Effective date: 20061002 |