EP1448204A1 - Neue trockene und wässrige epinastin-sirup-formulierung - Google Patents

Neue trockene und wässrige epinastin-sirup-formulierung

Info

Publication number
EP1448204A1
EP1448204A1 EP02802290A EP02802290A EP1448204A1 EP 1448204 A1 EP1448204 A1 EP 1448204A1 EP 02802290 A EP02802290 A EP 02802290A EP 02802290 A EP02802290 A EP 02802290A EP 1448204 A1 EP1448204 A1 EP 1448204A1
Authority
EP
European Patent Office
Prior art keywords
formulation according
powder formulation
epinastine
tablet
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02802290A
Other languages
English (en)
French (fr)
Inventor
Koichi Wada
Manabu Nakatani
Toshimitsu Ohki
Kenzo Toyoshima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of EP1448204A1 publication Critical patent/EP1448204A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP02802290A 2001-10-26 2002-10-08 Neue trockene und wässrige epinastin-sirup-formulierung Withdrawn EP1448204A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10152973A DE10152973A1 (de) 2001-10-26 2001-10-26 Neue trockene und wässrige Epinastin-Sirup-Formulierung
DE10152973 2001-10-26
PCT/EP2002/011250 WO2003037350A1 (en) 2001-10-26 2002-10-08 New dry and aqueous epinastine-syrup-formulation

Publications (1)

Publication Number Publication Date
EP1448204A1 true EP1448204A1 (de) 2004-08-25

Family

ID=7703856

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02802290A Withdrawn EP1448204A1 (de) 2001-10-26 2002-10-08 Neue trockene und wässrige epinastin-sirup-formulierung

Country Status (9)

Country Link
EP (1) EP1448204A1 (de)
JP (2) JP4564749B2 (de)
KR (1) KR20050034619A (de)
BR (1) BR0213488A (de)
CO (1) CO5580751A2 (de)
DE (1) DE10152973A1 (de)
EC (1) ECSP045087A (de)
MX (1) MXPA04003772A (de)
WO (1) WO2003037350A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1452177A1 (de) * 2003-02-27 2004-09-01 Boehringer Ingelheim International GmbH Pharmazeutische Zusammensetzungen welche Natriumlaurylsulfat als Bitterkeits-maskierenden Stoff enthalten
US20040247686A1 (en) * 2003-04-04 2004-12-09 Boehringer Ingelheim International Gmbh Pharmaceutical compositions comprising epinastine for the treatment of skin diseases
WO2005089803A2 (en) * 2004-03-24 2005-09-29 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment of skin diseases comprising a combination of epinastine and one or more additional minerals or one or more crude drugs
JP5132090B2 (ja) * 2006-06-16 2013-01-30 東和薬品株式会社 塩酸エピナスチンドライシロップ剤
CN105708808B (zh) * 2014-12-01 2018-11-27 重庆安格龙翔医药科技有限公司 一种盐酸依匹斯汀颗粒剂及其制备方法
CN105708840A (zh) * 2014-12-01 2016-06-29 重庆安格龙翔医药科技有限公司 一种盐酸依匹斯汀组合物
CN105708807B (zh) * 2014-12-01 2018-11-27 重庆安格龙翔医药科技有限公司 一种盐酸依匹斯汀细粒剂的制备方法
JP2020172486A (ja) * 2019-04-10 2020-10-22 参天製薬株式会社 エピナスチン又はその塩を含有する水性医薬組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3008944A1 (de) * 1980-03-08 1981-09-24 C.H. Boehringer Sohn, 6507 Ingelheim Dibenzimidazoazepine, ihre herstellung und verwendung
EP0658340A1 (de) * 1993-12-17 1995-06-21 Unilever N.V. Orale Zusammensetzungen
JPH0827034A (ja) * 1994-07-14 1996-01-30 Nikken Chem Co Ltd エリスリトール含有内用液剤
JPH0952849A (ja) * 1995-06-06 1997-02-25 Taisho Pharmaceut Co Ltd 感冒剤用組成物
DE19542281C2 (de) * 1995-11-14 1997-12-04 Boehringer Ingelheim Kg Verwendung von Epinastin für die Behandlung der Migräne
JPH1045576A (ja) * 1996-08-05 1998-02-17 Taisho Pharmaceut Co Ltd 鼻炎用内服薬
AU9187598A (en) * 1997-09-30 1999-04-23 Daiichi Pharmaceutical Co., Ltd. Oral preparation
JPH11302189A (ja) * 1998-04-21 1999-11-02 Taisho Pharmaceut Co Ltd 感冒用組成物
JP4731777B2 (ja) * 1999-10-12 2011-07-27 マルホ株式会社 経口医薬組成物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
None *
See also references of WO03037350A1 *

Also Published As

Publication number Publication date
JP2010132702A (ja) 2010-06-17
BR0213488A (pt) 2004-11-03
CO5580751A2 (es) 2005-11-30
DE10152973A1 (de) 2003-05-08
JP4564749B2 (ja) 2010-10-20
MXPA04003772A (es) 2004-07-30
KR20050034619A (ko) 2005-04-14
WO2003037350A1 (en) 2003-05-08
ECSP045087A (es) 2004-06-28
JP2005508364A (ja) 2005-03-31

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