EP1181219B1 - Ansatz zur abgabe und zerstäubung von flüssigen pharmazeutischen produkten - Google Patents

Ansatz zur abgabe und zerstäubung von flüssigen pharmazeutischen produkten Download PDF

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Publication number
EP1181219B1
EP1181219B1 EP00927317A EP00927317A EP1181219B1 EP 1181219 B1 EP1181219 B1 EP 1181219B1 EP 00927317 A EP00927317 A EP 00927317A EP 00927317 A EP00927317 A EP 00927317A EP 1181219 B1 EP1181219 B1 EP 1181219B1
Authority
EP
European Patent Office
Prior art keywords
tubular element
cavity
piece according
wall
end piece
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP00927317A
Other languages
English (en)
French (fr)
Other versions
EP1181219A1 (de
Inventor
Jean-Louis Bougamont
Pascal Hennemann
David Leuliet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Albea Le Treport SAS
Original Assignee
Rexam Sofab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rexam Sofab filed Critical Rexam Sofab
Priority to DK00927317T priority Critical patent/DK1181219T3/da
Publication of EP1181219A1 publication Critical patent/EP1181219A1/de
Application granted granted Critical
Publication of EP1181219B1 publication Critical patent/EP1181219B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/28Nozzles, nozzle fittings or accessories specially adapted therefor
    • B65D83/30Nozzles, nozzle fittings or accessories specially adapted therefor for guiding the flow of spray, e.g. funnels, hoods
    • B65D83/303Nozzles, nozzle fittings or accessories specially adapted therefor for guiding the flow of spray, e.g. funnels, hoods using extension tubes located in or at the outlet duct of the nozzle assembly
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/56Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant with means for preventing delivery, e.g. shut-off when inverted
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0089Dispensing tubes
    • B05B11/0091Dispensing tubes movable, e.g. articulated on the sprayer
    • B05B11/0094Dispensing tubes movable, e.g. articulated on the sprayer movement of the dispensing tube controlling a valve

Definitions

  • the present invention relates to a nozzle for dispensing and spraying liquid pharmaceuticals.
  • the invention applies to a tip of the type comprising a tubular element, provided with a first free end of a spray nozzle, and at its second end, of a rotary connector ensuring the connection with the conduit internal evacuation of a push button intended to cover the nozzle tube a sampling member mounted on said container.
  • Patent AU 10803/66 discloses a tip provided with a tubular element fitted at one end with a rotary connector ensuring the connection with the internal evacuation pipe of a push button capping a valve mounted on a container.
  • the rotary connector consists of a plug comprising a cylindrical cavity formed on the communicating push button with the duct and in which is housed in a rotary manner the end of the tubular element.
  • the end is provided with an orifice capable of communicate by rotation of the nozzle with a profile orifice similar made in the cavity of the push button to allow the product distribution.
  • this tip has volumes dead, which causes boot problems during the first spray.
  • the object of the present invention is to solve these problems techniques effectively.
  • a nozzle for the distribution of contained liquid pharmaceuticals in a container, of the type comprising a tubular element provided with a first free end of a spray nozzle and, at its second end, of a rotary connector ensuring the connection with the internal evacuation duct of a push button intended to cover a sampling member mounted on said container, said connector rotary consisting of a plug comprising a cavity cylindrical formed on said push button by communicating with the internal evacuation duct and into which comes to fit, joined and rotatably, the second end of the element tubular which is provided with a means for opening said duct, characterized in that said cylindrical cavity contains an axial rod integral with the push button, intended to be engaged inside the second end of said tubular element, leaving a space interlayer for product transfer while reducing volumes dead said means opening of the exhaust pipe being made up of a discontinuity either in the form a slot formed on an angular portion of the wall of the second end of the tubular element is in the form thickness reduction performed on an
  • said internal conduit outlet opens laterally into said cavity via an orifice ejection.
  • the tubular element and the push button have latching members capable of cooperating removable way to position the second end in a angular position for closing the exhaust duct.
  • said cavity is delimited by the wall of a cylindrical spout projecting from the side wall of the pushbutton.
  • the wall of said spout carries a peripheral rod intended to cooperate by snap-fastening with a profile groove complementary formed on the wall of the tubular element, for ensure the positioning and retention of its second end in said cavity.
  • the second end of the element tubular is provided with an external coaxial sleeve defining a spacer space in which the cylindrical spout of the pushbutton.
  • said tubular element has a bent or articulated intermediate zone.
  • a closed position of the internal duct evacuation corresponds to the downward orientation of the first end of the tubular element.
  • the length of the element tubular engaged in said cylindrical cavity is determined so to clear a free space between the bottom of said cavity and the edge longitudinal of said second end.
  • the tip of the invention offers a large number of possibilities orientation thus facilitating the taking of the drug in different opening positions suitable for spraying.
  • the tip preferably has only one lockable closing position, corresponding to an orientation down the tubular element, thus providing space minimum of the entire packaging (container and tip) for storage.
  • the nozzle shown in Figures 1A and 2A is more particularly intended for distributing and spraying products liquid or pasty pharmaceuticals from a container fitted with a sampling and / or metering device such as a pump or a valve (not shown).
  • a sampling and / or metering device such as a pump or a valve (not shown).
  • the entire packaging is generally referred to as mouthwash.
  • the removal organ has traditionally a nozzle tube, the end of which is intended to be capped by a push button 2 having an internal conduit 20 and having a upper face 2a suitable for manual support.
  • This nozzle comprises a tubular element 1, more or less long, provided at a first free end 1a with a nozzle spray 3, and at its second end 1b, of a rotary connector 11.
  • the connector 11 provides the hydraulic and mechanical connection between the tubular element 1 and the internal evacuation conduit 20 which extends the nozzle tube of the sampling device. Element rotation tubular 1 around the axis of the connector 11 provides a appropriate orientation of the spray nozzle 3.
  • the first end the of the tubular element 1 is connected to the second end 1b via a bent or articulated zone 13 intermediate.
  • the rotary connector 11 shown in detail in FIGS. 1B and 2B consists of a valve plug, comprising a cavity cylindrical 21 formed on the push button 2 and communicating with the internal evacuation conduit 20 via an ejection orifice 20a which here opens laterally into the cavity 21.
  • the second end 1b of the tubular element 1 comes fit together and rotatably in the cavity 21 by sealing thus sealingly the orifice 20a as shown in the Figure 1B.
  • the second end 1b of the tubular element 1 is provided on its side wall with a means for opening the orifice 20a.
  • This opening means consists of a discontinuity 10 of the wall of element 1, leaving a passage inside the cavity 21 lateral 21a for the liquid product.
  • the cavity 21 is delimited here by the wall of a cylindrical spout 24 projecting from the front side wall of the push button 2.
  • the cavity 21 contains an axial rod 22 integral with the bottom 23 and intended to be engaged inside the second end 1b of the tubular element 1 by providing an intermediate space 21c for the transfer of the liquid product to the nozzle 3.
  • the rod 22 allows in particular reduce dead volumes in the nozzle and the number of strokes priming to get the first spray.
  • the axis of the rod 22 is here merged with the axis of the cavity 21 and the axis of rotation of the tubular element 1.
  • the length of the tubular element 1 engaged in the cavity 21 is determined so as to leave a free space 21b between the bottom 23 of said cavity and the upstream longitudinal edge of the second end 1b.
  • the free space 21b allows, in the open position, the penetration of the product from the orifice 20a via the lateral passage 21a in the tubular element, 1 as shown schematically by the arrows.
  • the second end 1b of the tubular element is provided, in the embodiment of FIGS. 1A and 2A, of a coaxial sleeve external 12 delimiting with the wall of the second end 1b, a intermediate space 14 in which is housed the spout 24 of the push button 2 with a slight radial tightening.
  • the wall of the spout 24 carries a peripheral ring 24a intended to cooperate, by snap-fastening possibly removable, with a groove 12a of complementary profile formed on the wall of the element tubular, and here of the sleeve 12, to ensure positioning and retaining the second end 1b in the cavity 21.
  • the relative locations of the rod 24a and the groove 12a are determined according to the respective lengths of the second end 1b and of the cavity 21, in particular to spare the free space 21b, at the bottom of the cavity.
  • the sealed closure position of the orifice 20a of the duct here corresponds to the downward orientation (FIGS. 1A and 1B) of the first end 1a of the tubular element 1.
  • the tubular element 1 and the push button 2 include latching members (not shown) capable of cooperating with easily removable, for positioning and locking, by rotation lock, the second end 1b in an angular position shutter.
  • this cooperation will be accompanied by a click signaling to the user that the correct shutter position has been obtained.
  • the means for opening the discharge duct 20 consists of a discontinuity 10 in the form of a reduction in thickness of the wall of the tubular element 1. This reduction is carried out on a portion angular a.
  • the discontinuity 10 is in the form of a niche produced either by molding direct either by removal of material on an angular portion ⁇ of the wall of the tubular element 1.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)
  • Nozzles (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)

Claims (9)

  1. Endstück für die Ausgabe von flüssigen, in einem Behälter enthaltenen pharmazeutischen Produkten, vom Typ bestehend aus einem rohrförmigen Element (1), das an einem ersten freien Ende (1a) mit einer Sprühdüse (3) und an seinem zweiten Ende (1b) mit einer Drehverbindung (11) versehen ist, über die es mit dem inneren Ausstoßkanal (20) eines Druckknopfes (2) verbunden ist, der zur Abdeckung eines auf diesen Behälter montierten Entnahmeorgans dient, wobei besagte Drehverbindung (11) aus einer Hülse besteht, die einen in besagten Druckknopf (2) eingelassenen und mit dem inneren Ausstoßkanal (20) in Verbindung stehenden zylinderförmigen Hohlraum (21) umfasst, in den das zweite, mit einer Vorrichtung zur Öffnung des besagten Kanals (20) versehene Ende (1b) des rohrförmigen Elements (1) abdichtend und drehbar eingesetzt ist, dadurch gekennzeichnet, dass besagter zylinderförmiger Hohlraum (21) einen mit dem Druckknopf (2) fest verbundenen axialen Stift (22) umgibt, der dazu bestimmt ist, in das zweite Ende (1b) des besagten rohrförmigen Elements (1) eingeführt zu werden und dabei einen Zwischenraum (21c) für den Durchlass des Produkts bei gleichzeitiger Begrenzung von Toträumen zu bilden, wobei besagte Vorrichtung zur Öffnung des Ausstoßkanals aus einem Absatz (10) besteht, der entweder in Form einer Aussparung über einen winkelförmigen Teil (α) der Wand des zweiten Endes (1b) des rohrförmigen Elements (1) oder in Form einer Dickenminderung über einen winkelförmigen Teil (α) der Wand des zweiten Endes des rohrförmigen Elements (1) ausgebildet ist, um für das flüssige Produkt einen seitlichen Durchlass (21a) zu bieten.
  2. Nasenendstück nach Anspruch 1, dadurch gekennzeichnet, dass besagter innerer Ausstoßkanal (20) über eine Ausstoßöffnung (20a) seitlich in besagten Hohlraum (21) mündet.
  3. Endstück nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass das rohrförmige Element (1) und der Druckknopf (2) mit Rastelementen versehen sind, die in beweglicher Weise so zusammenwirken, dass das zweite Ende (1b) in eine den Ausstoßkanal (20) verschließende Winkelposition gebracht werden kann.
  4. Endstück nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass besagter Hohlraum (21) durch einen seitlich von der Wand des Druckknopfs (2) vorstehenden zylinderförmigen Schnabel (24) begrenzt wird.
  5. Endstück nach Anspruch 4, dadurch gekennzeichnet, dass die Wand des besagten Schnabels (24) einen ringförmigen Wulst (24a) trägt, der dazu bestimmt ist, mit einer in der Wand des rohrförmigen Elements (1) eingelassenen und ein entsprechendes Gegenprofil aufweisenden Nut (12a) einrastend zusammenzuwirken, um die Positionierung und den Rückhalt des zweiten Endes (1b) in besagten Hohlraum (21) zu gewährleisten.
  6. Endstück nach Anspruch 4 oder 5, dadurch gekennzeichnet, dass das zweite Ende (1b) des rohrförmigen Elements (1) mit einer äußeren Koaxialhülse (12) versehen ist, die einen Zwischenraum (14) abgrenzt, in dem der zylinderförmige Schnabel (24) des Druckknopfs (2) sitzt.
  7. Endstück nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass besagtes rohrförmige Element (1) einen abgewinkelten oder gelenkig ausgebildeten Zwischenbereich aufweist.
  8. Endstück nach Anspruch 7, dadurch gekennzeichnet, dass eine Verschlussposition des inneren Ausstoßkanals (20) der nach unten gerichteten Stellung des ersten Endes (1a) des rohrförmigen Elements (1) entspricht.
  9. Endstück nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass die in den zylindrischen Hohlraum (21) eingeführte Länge des rohrförmigen Elements (1) so festgelegt ist, dass sie einen Freiraum (21b) zwischen dem Boden (23) des besagten Hohlraums (21) und der Längswand des besagten zweiten Endes (1b) freigibt.
EP00927317A 1999-05-05 2000-05-05 Ansatz zur abgabe und zerstäubung von flüssigen pharmazeutischen produkten Expired - Lifetime EP1181219B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK00927317T DK1181219T3 (da) 1999-05-05 2000-05-05 Studs til afgivelse og forstövning af flydende farmaceutiske produkter

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9905694A FR2793221B1 (fr) 1999-05-05 1999-05-05 Embout pour la distribution et la pulverisation de produits pharmaceutiques liquides
FR9905694 1999-05-05
PCT/FR2000/001224 WO2000068110A1 (fr) 1999-05-05 2000-05-05 Embout pour la distribution et la pulverisation de produits pharmaceutiques liquides

Publications (2)

Publication Number Publication Date
EP1181219A1 EP1181219A1 (de) 2002-02-27
EP1181219B1 true EP1181219B1 (de) 2004-09-15

Family

ID=9545225

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00927317A Expired - Lifetime EP1181219B1 (de) 1999-05-05 2000-05-05 Ansatz zur abgabe und zerstäubung von flüssigen pharmazeutischen produkten

Country Status (15)

Country Link
US (1) US6513684B1 (de)
EP (1) EP1181219B1 (de)
JP (1) JP2002544071A (de)
CN (1) CN1170746C (de)
AT (1) ATE276167T1 (de)
AU (1) AU4574600A (de)
BR (1) BR0011313B1 (de)
CA (1) CA2370386A1 (de)
DE (1) DE60013813T2 (de)
DK (1) DK1181219T3 (de)
ES (1) ES2232449T3 (de)
FR (1) FR2793221B1 (de)
HK (1) HK1053453A1 (de)
PT (1) PT1181219E (de)
WO (1) WO2000068110A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7124915B2 (en) * 2004-06-07 2006-10-24 The Fountainhead Group, Inc. Handle assembly for providing a controllable discharge stream direction from a pressure container while maintaining a stable center of mass of the pressure container
JP2009279483A (ja) * 2008-05-20 2009-12-03 Hosiden Corp エアゾールの自動噴霧装置
US8167220B2 (en) * 2009-09-21 2012-05-01 Berlin Packaging, Llc Headpiece for actuator
US9227210B2 (en) * 2010-01-28 2016-01-05 Sun Solutions Ltd. Cap of spray mineral water bottle and multifunctional spray mineral water bottle
JP6116259B2 (ja) * 2013-01-25 2017-04-19 小林製薬株式会社 吐出器
CN206567126U (zh) * 2017-02-17 2017-10-20 深圳市博纳药包技术股份有限公司 一种连体式防脱转臂喷头
WO2019182745A1 (en) 2018-03-19 2019-09-26 Bryn Pharma, LLC Epinephrine spray formulations
CN111792187A (zh) * 2020-07-22 2020-10-20 四川以爱沐爱科技有限公司 一种高压摩丝瓶
US11794199B2 (en) * 2022-01-20 2023-10-24 Packaging Concepts Associates Holding, Inc. Folding extension nozzle and dispensing assembly

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3221950A (en) * 1963-10-09 1965-12-07 Valve Corp Of America Aerosol dispenser
US3272406A (en) * 1964-10-26 1966-09-13 Valve Corp Of America Directional applicator for handheld dispensers
US4690312A (en) * 1986-05-15 1987-09-01 S. C. Johnson & Son, Inc. Dual function cap
DE4438375A1 (de) * 1994-10-27 1996-05-02 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
FR2743544B1 (fr) * 1996-01-16 1998-02-20 Valois Dispositif de distribution de produit fluide pourvu d'une double securite
DE19756090A1 (de) * 1997-12-17 1999-06-24 Pfeiffer Erich Gmbh & Co Kg Spender für Medien

Also Published As

Publication number Publication date
US6513684B1 (en) 2003-02-04
ATE276167T1 (de) 2004-10-15
CN1170746C (zh) 2004-10-13
FR2793221B1 (fr) 2001-07-27
DE60013813T2 (de) 2005-11-10
BR0011313A (pt) 2002-03-19
HK1053453A1 (en) 2003-10-24
AU4574600A (en) 2000-11-21
ES2232449T3 (es) 2005-06-01
PT1181219E (pt) 2005-02-28
EP1181219A1 (de) 2002-02-27
CN1407942A (zh) 2003-04-02
DK1181219T3 (da) 2005-01-31
BR0011313B1 (pt) 2011-10-18
CA2370386A1 (en) 2000-11-16
JP2002544071A (ja) 2002-12-24
DE60013813D1 (de) 2004-10-21
WO2000068110A1 (fr) 2000-11-16
FR2793221A1 (fr) 2000-11-10

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