EP1181219A1 - Ansatz zur abgabe und zerstäubung von flüssigen pharmazeutischen produkten - Google Patents
Ansatz zur abgabe und zerstäubung von flüssigen pharmazeutischen produktenInfo
- Publication number
- EP1181219A1 EP1181219A1 EP00927317A EP00927317A EP1181219A1 EP 1181219 A1 EP1181219 A1 EP 1181219A1 EP 00927317 A EP00927317 A EP 00927317A EP 00927317 A EP00927317 A EP 00927317A EP 1181219 A1 EP1181219 A1 EP 1181219A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- tubular element
- piece according
- wall
- cavity
- end piece
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 6
- 239000000825 pharmaceutical preparation Substances 0.000 title claims description 5
- 229940127557 pharmaceutical product Drugs 0.000 title claims description 5
- 238000005507 spraying Methods 0.000 title description 6
- 239000007921 spray Substances 0.000 claims abstract description 6
- 239000012263 liquid product Substances 0.000 claims description 4
- 239000000047 product Substances 0.000 claims description 4
- 230000000295 complement effect Effects 0.000 claims description 3
- 230000014759 maintenance of location Effects 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 3
- 238000005070 sampling Methods 0.000 claims description 3
- 239000003814 drug Substances 0.000 abstract description 2
- 230000008878 coupling Effects 0.000 abstract 2
- 238000010168 coupling process Methods 0.000 abstract 2
- 238000005859 coupling reaction Methods 0.000 abstract 2
- 238000010079 rubber tapping Methods 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- 229940051866 mouthwash Drugs 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 235000011837 pasties Nutrition 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
- B65D83/28—Nozzles, nozzle fittings or accessories specially adapted therefor
- B65D83/30—Nozzles, nozzle fittings or accessories specially adapted therefor for guiding the flow of spray, e.g. funnels, hoods
- B65D83/303—Nozzles, nozzle fittings or accessories specially adapted therefor for guiding the flow of spray, e.g. funnels, hoods using extension tubes located in or at the outlet duct of the nozzle assembly
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
- B65D83/56—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant with means for preventing delivery, e.g. shut-off when inverted
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/0005—Components or details
- B05B11/0089—Dispensing tubes
- B05B11/0091—Dispensing tubes movable, e.g. articulated on the sprayer
- B05B11/0094—Dispensing tubes movable, e.g. articulated on the sprayer movement of the dispensing tube controlling a valve
Definitions
- the present invention relates to a nozzle for dispensing and spraying liquid pharmaceutical products.
- the invention applies to a nozzle of the type comprising a tubular element, provided at a first free end, with a spray nozzle, and, at its second end, with a rotary connector ensuring the connection with the internal discharge pipe of a push button intended to cover the nozzle tube of a sampling member mounted on said container.
- the present invention aims to solve this technical problem effectively.
- a nozzle of the preceding type in which the rotary connector consists of a plug comprising a cylindrical cavity formed on said push button by communicating with the internal evacuation duct and in which is fitted, in a contiguous and rotary manner, the second end of the tubular element which is provided with a means for opening said conduit.
- the cylindrical cavity contains an axial rod secured to the push button, intended to be engaged inside the second end of said tubular element while providing an intermediate space for the transfer of the product.
- said internal evacuation conduit opens laterally into said cavity via an ejection orifice.
- the tubular element and the push-button comprise latching members capable of cooperating in a removable manner to position the second end in an angular position for closing the evacuation duct.
- said cavity is delimited by the wall of a cylindrical spout projecting from the side wall of the push button.
- the wall of said spout carries a peripheral rod intended to cooperate by snap-fastening with a groove of complementary profile formed on the wall of the tubular element, to ensure the positioning and the retention of its second end in said cavity.
- the second end of the tubular element is provided with an external coaxial sleeve delimiting an intermediate space in which is housed the cylindrical spout of the push button.
- said means for opening the discharge duct consists of a discontinuity in the wall of the second end of the tubular element providing a lateral passage for the liquid product.
- said discontinuity is in the form of a niche formed on an angular portion of the wall of the tubular element.
- said discontinuity is in the form of a reduction in thickness produced on an angular portion of the wall of the tubular element.
- said tubular element has a bent or articulated intermediate zone.
- a closed position of the internal evacuation conduit corresponds to the downward orientation of the first end of the tubular element.
- the length of the tubular element engaged in said cylindrical cavity is determined so as to leave a free space between the bottom of said cavity and the longitudinal edge of said second end.
- the tip of the invention offers a large number of orientation possibilities, thus making it easier to take the medicament in different opening positions suitable for spraying.
- the end piece preferably has a single lockable closed position, corresponding to an orientation towards the bottom of the tubular element, thus offering a minimum bulk of the entire packaging (container and end piece) for storage.
- FIG. 1A shows a sectional view of the tip of the invention in the closed position
- FIG. 1B shows a detailed sectional view of the tip of Figure 1A
- - Figure 2A shows a sectional view of the nozzle of Figure 1A in the open position
- FIG. 2B shows a detailed sectional view of the nozzle of Figure 1A in the position of Figure 2A;
- FIG. 3 and 4 show sectional views along AA of two alternative embodiments of the rotary connector of the nozzle in the closed position.
- the nozzle shown in FIGS. 1A and 2A is more particularly intended for dispensing and spraying liquid or pasty pharmaceutical products from a container equipped with a sampling and / or dosing member such as a pump or a valve
- the withdrawing member conventionally has a nozzle tube, the end of which is intended to be capped by a push button 2 having an internal conduit 20 and having an upper face 2a suitable for manual support.
- This nozzle comprises a tubular element 1, more or less long, provided at a first free end 1a with a spray nozzle 3, and at its second end 1b, with a rotary connector 11.
- the connector 11 provides the hydraulic connection and mechanical between the tubular element 1 and the internal evacuation conduit 20 which extends the nozzle tube of the withdrawal member.
- the rotation of the tubular element 1 around the axis of the connector 11 makes it possible to obtain an appropriate orientation of the spray nozzle 3.
- the first end 1a of the tubular element 1 is connected to the second end 1b via a bent or articulated zone 13 intermediate.
- the rotary connector 11 shown in detail in FIGS. 1B and 2B consists of a plug forming a valve, comprising a cylindrical cavity 21 formed on the push button 2 and communicating with the internal evacuation conduit 20 via an ejection orifice 20a which here opens laterally into the cavity 21.
- the second end 1b of the tubular element 1 fits in a contiguous and rotary manner in the cavity 21, thereby sealingly sealing the orifice 20a as shown in FIG. 1B.
- the second end 1b of the tubular element 1 is provided on its side wall with a means for opening the orifice 20a.
- This opening means consists of a discontinuity 10 in the wall of the element 1, providing, inside the cavity 21, a lateral passage 21a for the liquid product.
- the cavity 21 is delimited here by the wall of a cylindrical spout 24 projecting from the front lateral wall of the push button 2.
- the cavity 21 contains an axial rod 22 integral with the bottom 23 and intended to be engaged inside of the second end 1b of the tubular element 1 by providing an intermediate space 21c for the transfer of the liquid product to the nozzle 3.
- the rod 22 makes it possible in particular to reduce the dead volumes in the nozzle and the number of priming strokes for get the first spray.
- the axis of the rod 22 is here merged with the axis of the cavity 21 and the axis of the rotation of the tubular element 1.
- the length of the tubular element 1 engaged in the cavity 21 is determined so as to leave a free space 21b between the bottom 23 of said cavity and the upstream longitudinal edge of the second end 1b.
- the free space 21b allows, in the open position, the penetration of the product from the orifice 20a via the lateral passage 21a in the tubular element , 1 as shown by the arrows.
- the second end lb of the tubular element is provided, in the embodiment of FIGS. 1A and 2A, with an external coaxial sleeve 12 delimiting with the wall of the second end lb, an intermediate space 14 in which the spout is housed 24 of push button 2 with a slight radial tightening.
- the wall of the spout 24 carries a peripheral ring 24a intended to cooperate, by snap-fitting possibly removable, with a groove 12a of complementary profile formed on the wall of the tubular element, and here of the sleeve 12, to ensure the positioning and the retention of the second end lb in the cavity 21.
- the relative locations of the rod 24a and the groove 12a are determined as a function of the respective lengths of the second end 1b and of the cavity 21, in particular to provide the free space 21b at the bottom of the cavity.
- the sealed closure position of the orifice 20a of the evacuation duct 20 here corresponds to the downward orientation (FIGS. 1A and 1B) of the first end 1a of the tubular element 1.
- the tubular element 1 and the push-button 2 comprise snap-fastening members (not shown) capable of cooperating in an easily removable manner, for positioning and locking, by rotationally blocking, the second end 1b in an angular obturation position. .
- this cooperation will be accompanied by a click signaling the user that the correct shutter position has been obtained.
- the means for opening the discharge conduit 20 consists of a discontinuity 10 in the form of a reduction in thickness of the wall of the element tubular 1. This reduction is carried out on an angular portion.
- the discontinuity 10 is in the form of a slot produced either by direct molding or by removal of material on an angular portion ⁇ from the wall of the tubular element 1.
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Closures For Containers (AREA)
- Nozzles (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Formation And Processing Of Food Products (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK00927317T DK1181219T3 (da) | 1999-05-05 | 2000-05-05 | Studs til afgivelse og forstövning af flydende farmaceutiske produkter |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9905694 | 1999-05-05 | ||
FR9905694A FR2793221B1 (fr) | 1999-05-05 | 1999-05-05 | Embout pour la distribution et la pulverisation de produits pharmaceutiques liquides |
PCT/FR2000/001224 WO2000068110A1 (fr) | 1999-05-05 | 2000-05-05 | Embout pour la distribution et la pulverisation de produits pharmaceutiques liquides |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1181219A1 true EP1181219A1 (de) | 2002-02-27 |
EP1181219B1 EP1181219B1 (de) | 2004-09-15 |
Family
ID=9545225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP00927317A Expired - Lifetime EP1181219B1 (de) | 1999-05-05 | 2000-05-05 | Ansatz zur abgabe und zerstäubung von flüssigen pharmazeutischen produkten |
Country Status (15)
Country | Link |
---|---|
US (1) | US6513684B1 (de) |
EP (1) | EP1181219B1 (de) |
JP (1) | JP2002544071A (de) |
CN (1) | CN1170746C (de) |
AT (1) | ATE276167T1 (de) |
AU (1) | AU4574600A (de) |
BR (1) | BR0011313B1 (de) |
CA (1) | CA2370386A1 (de) |
DE (1) | DE60013813T2 (de) |
DK (1) | DK1181219T3 (de) |
ES (1) | ES2232449T3 (de) |
FR (1) | FR2793221B1 (de) |
HK (1) | HK1053453A1 (de) |
PT (1) | PT1181219E (de) |
WO (1) | WO2000068110A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7124915B2 (en) * | 2004-06-07 | 2006-10-24 | The Fountainhead Group, Inc. | Handle assembly for providing a controllable discharge stream direction from a pressure container while maintaining a stable center of mass of the pressure container |
JP2009279483A (ja) * | 2008-05-20 | 2009-12-03 | Hosiden Corp | エアゾールの自動噴霧装置 |
US8167220B2 (en) * | 2009-09-21 | 2012-05-01 | Berlin Packaging, Llc | Headpiece for actuator |
US9227210B2 (en) * | 2010-01-28 | 2016-01-05 | Sun Solutions Ltd. | Cap of spray mineral water bottle and multifunctional spray mineral water bottle |
JP6116259B2 (ja) * | 2013-01-25 | 2017-04-19 | 小林製薬株式会社 | 吐出器 |
CN206567126U (zh) * | 2017-02-17 | 2017-10-20 | 深圳市博纳药包技术股份有限公司 | 一种连体式防脱转臂喷头 |
WO2019182745A1 (en) | 2018-03-19 | 2019-09-26 | Bryn Pharma, LLC | Epinephrine spray formulations |
CN111792187A (zh) * | 2020-07-22 | 2020-10-20 | 四川以爱沐爱科技有限公司 | 一种高压摩丝瓶 |
US11794199B2 (en) * | 2022-01-20 | 2023-10-24 | Packaging Concepts Associates Holding, Inc. | Folding extension nozzle and dispensing assembly |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3221950A (en) * | 1963-10-09 | 1965-12-07 | Valve Corp Of America | Aerosol dispenser |
US3272406A (en) * | 1964-10-26 | 1966-09-13 | Valve Corp Of America | Directional applicator for handheld dispensers |
US4690312A (en) * | 1986-05-15 | 1987-09-01 | S. C. Johnson & Son, Inc. | Dual function cap |
DE4438375A1 (de) * | 1994-10-27 | 1996-05-02 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
FR2743544B1 (fr) * | 1996-01-16 | 1998-02-20 | Valois | Dispositif de distribution de produit fluide pourvu d'une double securite |
DE19756090A1 (de) * | 1997-12-17 | 1999-06-24 | Pfeiffer Erich Gmbh & Co Kg | Spender für Medien |
-
1999
- 1999-05-05 FR FR9905694A patent/FR2793221B1/fr not_active Expired - Fee Related
-
2000
- 2000-05-05 AT AT00927317T patent/ATE276167T1/de not_active IP Right Cessation
- 2000-05-05 CA CA002370386A patent/CA2370386A1/en not_active Abandoned
- 2000-05-05 JP JP2000617100A patent/JP2002544071A/ja active Pending
- 2000-05-05 AU AU45746/00A patent/AU4574600A/en not_active Abandoned
- 2000-05-05 ES ES00927317T patent/ES2232449T3/es not_active Expired - Lifetime
- 2000-05-05 WO PCT/FR2000/001224 patent/WO2000068110A1/fr active IP Right Grant
- 2000-05-05 US US09/926,440 patent/US6513684B1/en not_active Expired - Lifetime
- 2000-05-05 DE DE60013813T patent/DE60013813T2/de not_active Expired - Lifetime
- 2000-05-05 PT PT00927317T patent/PT1181219E/pt unknown
- 2000-05-05 DK DK00927317T patent/DK1181219T3/da active
- 2000-05-05 EP EP00927317A patent/EP1181219B1/de not_active Expired - Lifetime
- 2000-05-05 BR BRPI0011313-1A patent/BR0011313B1/pt not_active IP Right Cessation
- 2000-05-05 CN CNB008085110A patent/CN1170746C/zh not_active Expired - Fee Related
-
2003
- 2003-08-14 HK HK03105814A patent/HK1053453A1/xx not_active IP Right Cessation
Non-Patent Citations (1)
Title |
---|
See references of WO0068110A1 * |
Also Published As
Publication number | Publication date |
---|---|
BR0011313A (pt) | 2002-03-19 |
ATE276167T1 (de) | 2004-10-15 |
BR0011313B1 (pt) | 2011-10-18 |
PT1181219E (pt) | 2005-02-28 |
EP1181219B1 (de) | 2004-09-15 |
AU4574600A (en) | 2000-11-21 |
DK1181219T3 (da) | 2005-01-31 |
US6513684B1 (en) | 2003-02-04 |
FR2793221A1 (fr) | 2000-11-10 |
DE60013813D1 (de) | 2004-10-21 |
CN1407942A (zh) | 2003-04-02 |
CA2370386A1 (en) | 2000-11-16 |
WO2000068110A1 (fr) | 2000-11-16 |
JP2002544071A (ja) | 2002-12-24 |
FR2793221B1 (fr) | 2001-07-27 |
ES2232449T3 (es) | 2005-06-01 |
DE60013813T2 (de) | 2005-11-10 |
HK1053453A1 (en) | 2003-10-24 |
CN1170746C (zh) | 2004-10-13 |
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