EP1059989A1 - Anlage und verfahren zur filtration und sammlung von blut oder blutprodukten - Google Patents
Anlage und verfahren zur filtration und sammlung von blut oder blutproduktenInfo
- Publication number
- EP1059989A1 EP1059989A1 EP99909743A EP99909743A EP1059989A1 EP 1059989 A1 EP1059989 A1 EP 1059989A1 EP 99909743 A EP99909743 A EP 99909743A EP 99909743 A EP99909743 A EP 99909743A EP 1059989 A1 EP1059989 A1 EP 1059989A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- blood
- tubing
- length
- product
- blood product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D36/00—Filter circuits or combinations of filters with other separating devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0231—Multiple bag systems for separating or storing blood components with gas separating means, e.g. air outlet through microporous membrane or gas bag
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
Definitions
- This invention relates generally to liquid filtration techniques. More
- this invention relates to an in-line gravity driven liquid filtration method usable to filter and collect biological liquids such as blood or blood products.
- blood filtration devices allow liquid filtrate to remain within the
- This remaining liquid referred to as a
- filtration devices allow an undesirably high amount of air that is purged therefrom to
- the filtration method of the present invention is useable when
- blood products involves filtering the blood or blood product, collecting the blood or
- a receiving bag e.g., a conventional transfer or storage bag
- the blood in the sealed segments of the first length of tubing may then be used for cross-matching, and/or the blood sealed in the segments of the second length of tubing may be used for
- the air within the receiving bag may be expressed into an air bag which is
- the blood or blood product may be filtered for removal of cells and
- the blood or blood product within the segments of the second length of tubing may be any blood or blood product within the segments of the second length of tubing.
- the filtered cells may be
- the blood or blood product may be filtered
- first and second lengths of tubing may be sealed using a heat sealing device.
- the blood or blood product may be filtered for removal of cells and
- the blood or blood product within the segments of the second length of tubing may be any blood or blood product within the segments of the second length of tubing.
- the filtered cells may be
- the blood or blood product may be filtered
- first and second lengths of tubing may be sealed using a heat sealing device.
- Figure 1 depicts a filtration device in an operational assembly with a blood
- Figure 2 depicts an isometric view of a receiving blood bag, air bag, air bag
- upstream, top or up refers to a location of the flow of liquid prior to filtration through filter elements within the filtration device of
- the present invention is intended to be used for in-line gravity filtration of
- the filtration device used should automatically drain the upstream side when filtration is complete. Preferably, draining occurs without the manipulation of
- One type of filtration device, useable in the present invention incorporates an
- a filtration device 223 is depicted in operational
- bag 294 air bag 295, inlet tube clamp 266, outlet tube clamp 267, and air tube clamp
- inlet tube clamp 266 For performing filtration, inlet tube clamp 266,
- tube clamp 267 is opened and air tube clamp 268, preferably located close to the air
- socket 287 above the center of inlet section 201 may now be attached to a feed blood
- feed blood bag 293 may be hung from hook 297 on blood bag pole
- Receiving blood bag 294 and air bag 295 could be placed on a surface such as a
- feed blood bag 293 is empty it will be collapsed and therefore, close the inlet end of
- tube clamp 267 located between the filtration device
- tube clamp 267 can be sealed, typically by heat using a conventional heat
- safety device which closes portions of tubing by melting the same, by clamping the tubing closed or by any other means to temporarily or permanently seal or close the
- the blood may now be mixed to ensure consistency, and preferably the blood is mixed after the air is removed, though mixing could occur before removing the air if desired.
- mixed blood from receiving blood bag 294 can be expressed into air bag tubing 298 to
- Tube clamp 268 can now be closed and air bag tubing 298 sealed near
- Air bag 295 can be any of the means similar to that for tubing 218. Air bag 295 can be any of the means similar to that for tubing 218. Air bag 295 can be any of the means similar to that for tubing 218. Air bag 295 can be any of the means similar to that for tubing 218. Air bag 295 can be any of the means similar to that for tubing 218. Air bag 295 can be any of the means similar to that for tubing 218. Air bag 295 can be any of the air bag 295, using any of the means similar to that for tubing 218. Air bag 295 can be any of the means similar to that for tubing 218. Air bag 295.
- Both outlet tubing 218 and air bag tubing 298 may have segment marks
- Figure 2 depicts the segment marks 292 on air bag tubing 298.
- the blood that is sealed in the segments in outlet tubing 218 may be tested for its compatibility with a patient
- segments of air bag tubing 298 may be tested for the concentration of filtered matter
- the filtered blood sealed in tubing 298 may be tested for the presence and
- agents can be tested for the presence and concentration of such agents after filtration.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7655898P | 1998-03-02 | 1998-03-02 | |
US76558P | 1998-03-02 | ||
PCT/US1999/004544 WO1999044718A1 (en) | 1998-03-02 | 1999-03-02 | System and method of filtering and collecting blood or blood products |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1059989A1 true EP1059989A1 (de) | 2000-12-20 |
EP1059989A4 EP1059989A4 (de) | 2001-08-22 |
Family
ID=22132781
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP99909743A Withdrawn EP1059989A4 (de) | 1998-03-02 | 1999-03-02 | Anlage und verfahren zur filtration und sammlung von blut oder blutprodukten |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1059989A4 (de) |
JP (1) | JP2003501112A (de) |
KR (1) | KR20010074437A (de) |
CN (1) | CN1227764A (de) |
AU (1) | AU2888299A (de) |
BR (1) | BR9908445A (de) |
CA (1) | CA2321762A1 (de) |
IL (1) | IL138082A0 (de) |
WO (1) | WO1999044718A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002173433A (ja) * | 2000-12-04 | 2002-06-21 | Terumo Corp | 白血球除去血液製剤の調製方法および血液セット |
DE102004035352B4 (de) | 2004-07-21 | 2007-05-10 | Gerätezentrale für Bluttransfusion des Österreichischen Roten Kreuzes GmbH | Geschlossenes steriles System zum Filtrieren von biologischen oder medizinischen Flüssigkeiten, insbesondere von Vollblut |
WO2006016421A1 (ja) * | 2004-08-12 | 2006-02-16 | Jms Co., Ltd. | 濾過装置及び濾過方法 |
US10159778B2 (en) | 2014-03-24 | 2018-12-25 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
US9968738B2 (en) | 2014-03-24 | 2018-05-15 | Fenwal, Inc. | Biological fluid filters with molded frame and methods for making such filters |
US9782707B2 (en) | 2014-03-24 | 2017-10-10 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
US10376627B2 (en) | 2014-03-24 | 2019-08-13 | Fenwal, Inc. | Flexible biological fluid filters |
US9796166B2 (en) | 2014-03-24 | 2017-10-24 | Fenwal, Inc. | Flexible biological fluid filters |
WO2016148265A1 (ja) * | 2015-03-18 | 2016-09-22 | テルモ株式会社 | 遠心分離機及びセグメント保持部 |
CN106577636B (zh) * | 2016-12-29 | 2018-01-30 | 银丰生物工程集团有限公司 | 一种符合无菌操作要求的新型细胞冻存袋及使用方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0349188B1 (de) * | 1988-06-23 | 1992-09-02 | ASAHI MEDICAL Co., Ltd. | Verfahren zur Trennung von Blut in Blutkomponenten und Einheit zur Trennung von Blutkomponenten |
US5690815A (en) * | 1992-07-13 | 1997-11-25 | Pall Corporation | Automated system for processing biological fluid |
EP0879608A2 (de) * | 1997-03-24 | 1998-11-25 | Fresenius AG | Vorrichtung und Verfahren zum Trennen von Blut in Blutkomponenten |
EP0988103A1 (de) * | 1997-03-06 | 2000-03-29 | Hemasure, Inc. | Vorrichtung zur gravitativen filtration verwendbar zum filtern von blut oder blutprodukten |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2086516C (en) * | 1991-05-08 | 2002-11-12 | Donald H. Buchholz | Methods for processing red blood cell products for long term storage free of microorganisms |
US5180504A (en) * | 1991-05-22 | 1993-01-19 | Baxter International Inc. | Systems and methods for removing undesired matter from blood cells |
GB9218581D0 (en) * | 1992-09-02 | 1992-10-14 | Pall Corp | Removal of unwanted fluids from processed blood products |
US5527472A (en) * | 1993-06-14 | 1996-06-18 | Baxter International Inc. | Closed systems and methods for removing undesired matter from blood cells |
-
1998
- 1998-10-14 CN CN98120415A patent/CN1227764A/zh active Pending
-
1999
- 1999-03-02 BR BR9908445-7A patent/BR9908445A/pt not_active Application Discontinuation
- 1999-03-02 WO PCT/US1999/004544 patent/WO1999044718A1/en not_active Application Discontinuation
- 1999-03-02 AU AU28882/99A patent/AU2888299A/en not_active Abandoned
- 1999-03-02 JP JP2000534310A patent/JP2003501112A/ja active Pending
- 1999-03-02 IL IL13808299A patent/IL138082A0/xx unknown
- 1999-03-02 EP EP99909743A patent/EP1059989A4/de not_active Withdrawn
- 1999-03-02 KR KR1020007009657A patent/KR20010074437A/ko active Search and Examination
- 1999-03-02 CA CA002321762A patent/CA2321762A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0349188B1 (de) * | 1988-06-23 | 1992-09-02 | ASAHI MEDICAL Co., Ltd. | Verfahren zur Trennung von Blut in Blutkomponenten und Einheit zur Trennung von Blutkomponenten |
US5690815A (en) * | 1992-07-13 | 1997-11-25 | Pall Corporation | Automated system for processing biological fluid |
EP0988103A1 (de) * | 1997-03-06 | 2000-03-29 | Hemasure, Inc. | Vorrichtung zur gravitativen filtration verwendbar zum filtern von blut oder blutprodukten |
EP0879608A2 (de) * | 1997-03-24 | 1998-11-25 | Fresenius AG | Vorrichtung und Verfahren zum Trennen von Blut in Blutkomponenten |
Non-Patent Citations (1)
Title |
---|
See also references of WO9944718A1 * |
Also Published As
Publication number | Publication date |
---|---|
KR20010074437A (ko) | 2001-08-04 |
AU2888299A (en) | 1999-09-20 |
WO1999044718A8 (en) | 2000-02-10 |
CN1227764A (zh) | 1999-09-08 |
CA2321762A1 (en) | 1999-09-10 |
WO1999044718A1 (en) | 1999-09-10 |
IL138082A0 (en) | 2001-10-31 |
BR9908445A (pt) | 2000-11-14 |
JP2003501112A (ja) | 2003-01-14 |
EP1059989A4 (de) | 2001-08-22 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20000918 |
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Effective date: 20010710 |
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Free format text: 7B 01D 36/00 A, 7B 01D 37/00 B, 7A 61M 5/36 B, 7A 61M 5/165 B |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20011002 |