EP0823486A3 - Verfahren zur Hemmung der Bindung von DNA-Bindungsproteinen mit Duplex-DNA - Google Patents
Verfahren zur Hemmung der Bindung von DNA-Bindungsproteinen mit Duplex-DNA Download PDFInfo
- Publication number
- EP0823486A3 EP0823486A3 EP97114919A EP97114919A EP0823486A3 EP 0823486 A3 EP0823486 A3 EP 0823486A3 EP 97114919 A EP97114919 A EP 97114919A EP 97114919 A EP97114919 A EP 97114919A EP 0823486 A3 EP0823486 A3 EP 0823486A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- binding
- dna
- inhibiting
- protein
- binding protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72361891A | 1991-06-27 | 1991-06-27 | |
US723618 | 1991-06-27 | ||
EP92915116A EP0593618B1 (de) | 1991-06-27 | 1992-06-26 | Screeningtest für den nachweis von dna-bindenden molekülen |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP92915116A Division EP0593618B1 (de) | 1991-06-27 | 1992-06-26 | Screeningtest für den nachweis von dna-bindenden molekülen |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0823486A2 EP0823486A2 (de) | 1998-02-11 |
EP0823486A3 true EP0823486A3 (de) | 2004-02-11 |
Family
ID=24907008
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP92915116A Expired - Lifetime EP0593618B1 (de) | 1991-06-27 | 1992-06-26 | Screeningtest für den nachweis von dna-bindenden molekülen |
EP97114919A Withdrawn EP0823486A3 (de) | 1991-06-27 | 1992-06-26 | Verfahren zur Hemmung der Bindung von DNA-Bindungsproteinen mit Duplex-DNA |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP92915116A Expired - Lifetime EP0593618B1 (de) | 1991-06-27 | 1992-06-26 | Screeningtest für den nachweis von dna-bindenden molekülen |
Country Status (12)
Country | Link |
---|---|
US (5) | US5693463A (de) |
EP (2) | EP0593618B1 (de) |
JP (1) | JP3169610B2 (de) |
KR (1) | KR100235575B1 (de) |
AT (1) | ATE165397T1 (de) |
AU (1) | AU655839B2 (de) |
CA (1) | CA2112130C (de) |
DE (1) | DE69225227T2 (de) |
DK (1) | DK0593618T3 (de) |
ES (1) | ES2117050T3 (de) |
HK (1) | HK1010058A1 (de) |
WO (1) | WO1993000446A1 (de) |
Families Citing this family (108)
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US20030104361A1 (en) * | 1997-09-29 | 2003-06-05 | Susan Weininger | Method of detection of nucleic acids with a specific sequence composition |
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US20060063193A1 (en) * | 1995-04-11 | 2006-03-23 | Dong-Jing Fu | Solid phase sequencing of double-stranded nucleic acids |
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US6506906B1 (en) | 1996-02-26 | 2003-01-14 | California Institute Of Technology | Preparation and use of bifunctional molecules having DNA sequence binding specificity |
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US6635417B1 (en) | 1996-07-31 | 2003-10-21 | California Institute Of Technology | Complex formation between DSDNA and oligomer of cyclic heterocycles |
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Citations (3)
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WO1987004170A1 (en) * | 1986-01-09 | 1987-07-16 | Massachusetts Institute Of Technology | Nuclear factors associated with transcriptional regulation |
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US4942227A (en) * | 1982-01-11 | 1990-07-17 | California Institute Of Technology | Bifunctional molecules having a DNA intercalator or DNA groove binder linked to ethylene diamine tetraacetic acid, their preparation and use to cleave DNA |
US4665184A (en) * | 1983-10-12 | 1987-05-12 | California Institute Of Technology | Bifunctional molecules having a DNA intercalator or DNA groove binder linked to ethylene diamine tetraacetic acid |
US5071773A (en) * | 1986-10-24 | 1991-12-10 | The Salk Institute For Biological Studies | Hormone receptor-related bioassays |
US5096815A (en) * | 1989-01-06 | 1992-03-17 | Protein Engineering Corporation | Generation and selection of novel dna-binding proteins and polypeptides |
CA2092000A1 (en) * | 1990-09-24 | 1992-03-25 | Roger Brent | Screening assays |
WO1992013063A1 (en) * | 1991-01-18 | 1992-08-06 | Oncogene Science, Inc. | Methods of transcriptionally modulating expression of growth factor genes and growth factor receptor genes |
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DE69225227T2 (de) * | 1991-06-27 | 1998-10-29 | Genelabs Tech Inc | Screeningtest für den nachweis von dna-bindenden molekülen |
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1992
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- 1992-06-26 JP JP50170593A patent/JP3169610B2/ja not_active Expired - Fee Related
- 1992-06-26 AU AU22978/92A patent/AU655839B2/en not_active Ceased
- 1992-06-26 ES ES92915116T patent/ES2117050T3/es not_active Expired - Lifetime
- 1992-06-26 KR KR1019930704049A patent/KR100235575B1/ko not_active IP Right Cessation
- 1992-06-26 WO PCT/US1992/005476 patent/WO1993000446A1/en active IP Right Grant
- 1992-06-26 EP EP97114919A patent/EP0823486A3/de not_active Withdrawn
- 1992-12-23 US US07/996,783 patent/US5693463A/en not_active Expired - Lifetime
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US4270924A (en) * | 1979-04-10 | 1981-06-02 | Crooke Stanley T | Diagnostic method for detecting cancer |
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Also Published As
Publication number | Publication date |
---|---|
HK1010058A1 (en) | 1999-06-11 |
EP0593618A1 (de) | 1994-04-27 |
DK0593618T3 (da) | 1998-11-23 |
US5716780A (en) | 1998-02-10 |
DE69225227D1 (de) | 1998-05-28 |
US5306619A (en) | 1994-04-26 |
EP0823486A2 (de) | 1998-02-11 |
JP3169610B2 (ja) | 2001-05-28 |
ES2117050T3 (es) | 1998-08-01 |
EP0593618B1 (de) | 1998-04-22 |
CA2112130C (en) | 1996-08-06 |
US5744131A (en) | 1998-04-28 |
CA2112130A1 (en) | 1993-01-07 |
ATE165397T1 (de) | 1998-05-15 |
DE69225227T2 (de) | 1998-10-29 |
JPH07500491A (ja) | 1995-01-19 |
WO1993000446A1 (en) | 1993-01-07 |
AU2297892A (en) | 1993-01-25 |
AU655839B2 (en) | 1995-01-12 |
US5738990A (en) | 1998-04-14 |
KR100235575B1 (ko) | 1999-12-15 |
US5693463A (en) | 1997-12-02 |
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