EP0931834A3 - Echinocandin-bindungsdomäne von 1,3-Beta-glukan Synthase - Google Patents

Echinocandin-bindungsdomäne von 1,3-Beta-glukan Synthase Download PDF

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Publication number
EP0931834A3
EP0931834A3 EP98310497A EP98310497A EP0931834A3 EP 0931834 A3 EP0931834 A3 EP 0931834A3 EP 98310497 A EP98310497 A EP 98310497A EP 98310497 A EP98310497 A EP 98310497A EP 0931834 A3 EP0931834 A3 EP 0931834A3
Authority
EP
European Patent Office
Prior art keywords
glucan synthase
binding domain
echinocandin
beta
glucan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98310497A
Other languages
English (en)
French (fr)
Other versions
EP0931834A2 (de
Inventor
Doreen Ma
Colleen Kay Dixon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of EP0931834A2 publication Critical patent/EP0931834A2/de
Publication of EP0931834A3 publication Critical patent/EP0931834A3/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP98310497A 1997-12-23 1998-12-21 Echinocandin-bindungsdomäne von 1,3-Beta-glukan Synthase Withdrawn EP0931834A3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6865897P 1997-12-23 1997-12-23
US68658P 1997-12-23

Publications (2)

Publication Number Publication Date
EP0931834A2 EP0931834A2 (de) 1999-07-28
EP0931834A3 true EP0931834A3 (de) 2002-06-26

Family

ID=22083932

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98310497A Withdrawn EP0931834A3 (de) 1997-12-23 1998-12-21 Echinocandin-bindungsdomäne von 1,3-Beta-glukan Synthase

Country Status (3)

Country Link
EP (1) EP0931834A3 (de)
JP (1) JPH11243977A (de)
CA (1) CA2255140A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7709444B2 (en) 1999-03-03 2010-05-04 Pfizer Inc. Echinocandin pharmaceutical formulations containing micelle-forming surfactants
US7790744B2 (en) 1992-03-19 2010-09-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1137663E (pt) 1998-12-09 2006-12-29 Lilly Co Eli Purificação de compostos ciclopéptidos equinocandina
WO2000052037A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Echinocandin/carbohydrate complexes
CA2362482A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
US20060074014A1 (en) 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
HUE041133T2 (hu) 2002-11-18 2019-05-28 Vicuron Pharmaceuticals Llc Dalbavancin adagolási módszer bakteriális fertõzések kezelésére
US7119061B2 (en) 2002-11-18 2006-10-10 Vicuron Pharmaceuticals, Inc. Dalbavancin compositions for treatment of bacterial infections
EP1907588B1 (de) * 2005-07-26 2013-06-05 The University of Medicine and Dentistry of New Jersey Tests auf resistenz zu arzneistoffen der echinocandin-klasse
AU2012230095B2 (en) * 2005-07-26 2015-05-28 Merck Sharp & Dohme Corp. Assays for resistance to echinocandin-class drugs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010625A1 (en) * 1993-10-12 1995-04-20 Merck & Co., Inc. Dna encoding 1,3-beta-d glucan synthase subunits

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010625A1 (en) * 1993-10-12 1995-04-20 Merck & Co., Inc. Dna encoding 1,3-beta-d glucan synthase subunits

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DOUGLAS C M ET AL: "Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 41, no. 11, November 1997 (1997-11-01), United States, pages 2471 - 2479, XP000107858 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7790744B2 (en) 1992-03-19 2010-09-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US7709444B2 (en) 1999-03-03 2010-05-04 Pfizer Inc. Echinocandin pharmaceutical formulations containing micelle-forming surfactants

Also Published As

Publication number Publication date
EP0931834A2 (de) 1999-07-28
CA2255140A1 (en) 1999-06-23
JPH11243977A (ja) 1999-09-14

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