EP0617949A1 - Bouteille de perfusion - Google Patents

Bouteille de perfusion Download PDF

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Publication number
EP0617949A1
EP0617949A1 EP93117945A EP93117945A EP0617949A1 EP 0617949 A1 EP0617949 A1 EP 0617949A1 EP 93117945 A EP93117945 A EP 93117945A EP 93117945 A EP93117945 A EP 93117945A EP 0617949 A1 EP0617949 A1 EP 0617949A1
Authority
EP
European Patent Office
Prior art keywords
infusion bottle
cover cap
sealing element
puncture site
puncture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93117945A
Other languages
German (de)
English (en)
Inventor
Klaus Derksen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pohl GmbH and Co KG
Original Assignee
Pohl GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pohl GmbH and Co KG filed Critical Pohl GmbH and Co KG
Publication of EP0617949A1 publication Critical patent/EP0617949A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1406—Septums, pierceable membranes

Definitions

  • the invention relates to a plastic infusion bottle provided with a cup-like bulge, in which the bulge has a pierceable base against which a pierceable sealing element made of polymeric material is pressed by means of a cover cap, the cover cap and the bulge being connected in a liquid-tight manner.
  • Such an infusion bottle is known from DE-PS 23 27 554.
  • the known infusion bottle is provided with a closure cap which comprises a tear-off cover part which covers a seal made of elastomeric material.
  • the lid part of the closure cap must first be removed so that the pierceable sealing element is exposed. A cannula can then penetrate the sealing element to remove the infusion liquid from the bottle.
  • the manufacture of the closure cap with the pull-out cover part which is delimited by a perforation, is unsatisfactory in terms of production engineering and economy.
  • the handling of the closure cap is problematic in the case of small mouth diameters of the infusion bottle, since the lid part provided with the tear-off tab is then difficult to remove.
  • the invention has for its object to further develop an infusion bottle of the known type such that it is easier to manufacture in terms of manufacturing technology and can be produced more economically.
  • the removal of the infusion fluid from the infusion bottle should be simplified.
  • the cover cap has at least one puncture point which can be pierced without the prior removal of components and which at least partially overlaps with one puncture point of the sealing element and of the base.
  • the advantage here is that the infusion bottle consists of only a few individual parts and is largely made of the same material.
  • the uncomplicated design of the cover cap means that the entire infusion bottle can be manufactured inexpensively. Because there is no need for a tear-open cover part in the area of the cover cap, predetermined breaking points and perforations in this area are unnecessary.
  • it is advantageous that the infusion liquid can be removed from the infusion bottle more quickly if necessary, since the entire cover cap can be pierced by a cannula without the removal of components.
  • the cover cap is first pierced in the area of its puncture site and then the sealing element with the cannula.
  • the elastomeric material of the sealing element surrounds the cannula sealingly under radial prestress, so that even with the mouth of the infusion bottle hanging down, no liquid components escape past it into the open.
  • the cover cap can have a wall thickness at the puncture site that is less than in the zones surrounding the puncture site.
  • the advantage here is that, on the one hand, a reliable, germ-free sealing of the infusion bottle is ensured before the liquid is removed and, on the other hand, that the cap can be pushed through with little effort.
  • the wall thickness of the cover cap in the area of the puncture point can be thin and have a material thickness of 0.1 to 0.8 mm.
  • the puncture site can be limited in a circle and have a wall thickness in the area of the puncture site that is increasingly reduced radially towards the center.
  • This configuration ensures that the puncture point of the cover cap is not opened further than is absolutely necessary for the cannula to be inserted.
  • the wall thickness is the smallest in the middle in the area of the puncture point of the cover cap.
  • the trough-shaped depression of the puncture site can be arranged on the side of the cap facing away from the infusion bottle.
  • the advantage here is that the puncture site can be easily recognized by the operating personnel without the need for secondary aids, such as a marking.
  • the puncture point can be provided on the side of the cover cap facing the sealing element. It is advantageous here that the cover cap on the side facing away from the container has a flat surface without depressions and projections. The smooth surface of the cover cap makes cleaning in this area particularly easy, for example after long storage of the closed container.
  • At least one holding element can be provided on the cover cap that surrounds the sealing element radially outside the puncture point. This prevents the sealing element from escaping in the radial direction. A corresponding axial prestress on the sealing element is maintained even during long storage of the closed infusion bottle.
  • a holding element can be formed by a sleeve-shaped extension of the cover cap, which surrounds the sealing element on the outside.
  • the size of the Compression that results between the sealing element, the infusion bottle, the cannula inserted into the infusion bottle and the cover cap can be achieved by varying the elastic compliance of the sealing element.
  • the holding claw can, for example, be provided with an undercut that can be snapped into the sealing element.
  • the sealing element preferably consists of a thermoplastic elastomer material (TPE) which contains a polyolefin. It is therefore easy and inexpensive to process and can be recycled together with the material body that forms the infusion bottle and consists of a polyolefin. It is not necessary to separate the sealing element, infusion bottle and cover cap after use.
  • the Shore A hardness of the sealing element is preferably 45 to 60. Such a hardness on the one hand gives the pierced cannula the necessary hold and on the other hand ensures an excellent seal of the infusion fluid. In addition, cannulas with different diameters can be used.
  • the excellent usage properties of the sealing element are based on the fact that it is elastically expanded by the inserted cannula and, on the one hand, the cover cap and, on the other hand, the pot-like bulge of the infusion bottle are pressed in the axial direction by the contact.
  • the cover cap and the sealing element can be spaced apart from one another at the puncture site.
  • the advantage here is that the cap can be pierced with a comparatively reduced effort and deformation of the cannula can be avoided.
  • the distance means that the cover cap is initially subjected to elastic tension in the area of its puncture site during the insertion of the cannula and can therefore be pierced with less effort.
  • the size of the distance is essentially dependent on the elastic compliance of the material of the cover cap.
  • the cap can be made of plastic containing a microbicidal material. This simplifies the hermetic and germ-free sealing of the contents of the infusion bottle.
  • FIG. 1 and 2 show a first embodiment of the infusion bottle according to the invention, in which the pierceable sealing element is disc-shaped and has flat surfaces.
  • a second embodiment which has a pierceable sealing element, the sealing element being provided with a removal point of relatively reduced wall thickness.
  • the infusion bottle 1 shows a first exemplary embodiment of the infusion bottle 1 according to the invention, which consists of a thermoplastic elastomeric material.
  • the infusion bottle 1 is provided with a pot-like bulge 2 and closed by a pierceable base 3.
  • a sealing element 4 made of elastomeric material is arranged, which is held in an annular holding element 8 formed integrally with the cover cap 5 and in the axial direction between the cover cap 5 and the bottom 3 is arranged liquid-tight.
  • the cover cap 5 is provided with a puncture point 6 which can be pierced by a cannula and a recess 7 adjacent to the puncture point 6.
  • the recess 7 is provided in order to enrich the infusion liquid in the infusion bottle 1 with another medicament.
  • the recess 7, the cap 5, the sealing element 4 and the bottom 3 are penetrated by a syringe.
  • the puncture point 6 and the puncture point 7 of the cover cap 5 have a reduced wall thickness relative to the adjacent areas.
  • the holding element 8 is formed in one piece with the cover cap 5 and encloses the sealing element 4 on the outer circumference with radial prestress.
  • the cover cap 5 and the sealing element 4 are a preassembled unit form, which is placed on the pot-like bulge of the infusion bottle 1 and connected to it.
  • the bulge 2 is provided with an annular collar which is positively encompassed by the cover cap 5 and welded to it.
  • FIG. 2 shows the top view of the cover cap 5 from FIG. 1.
  • the puncture site 6 and the adjacent recess 7 have diameters that differ from one another and are adapted to the respective spike.
  • the annular retaining element 8, which surrounds the sealing element 4 on the outer circumference, is shown with dashed lines.
  • the sealing element 4 is provided with recesses in the axial direction on both sides in the area of the puncture point 6 of the cover cap 5. Due to the reduced material thickness of the sealing element 4, a cannula can be inserted into the infusion bottle 1 with a relatively reduced expenditure of force. Due to the concavities of the surface of the sealing element 4 arranged on both sides in the axial direction, sealing lips are formed after the piercing, which sealingly enclose the cannula under radial prestress. The sealing lips are deformed during the insertion in the direction of the infusion bottle and thereby form a barb-shaped captive device for the cannula, even when the infusion bottle 1 is arranged hanging.
  • the sealing element 4 is on the opposite of the recess 7 Place provided with a recess 10, wherein the recess 10 is dimensioned such that it surrounds a pierced spike sealingly under radial prestress.
  • FIG. 4 shows the top view of the cover cap 5 from FIG. 3.
  • the puncture site 6 and the indentation 7 are each delimited in a circle and have a trough shape.
  • the holding element 8, which is also formed in one piece with the cover cap 5 in this exemplary embodiment, is shown with dashed lines.
  • the cover cap 5, the sealing element 4 and the infusion bottle 1 each consist of a thermoplastic elastomer material that is easy and inexpensive to process. It is important to note that the entire infusion bottle can be recycled without disassembling individual parts.
EP93117945A 1993-03-25 1993-11-05 Bouteille de perfusion Withdrawn EP0617949A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4309737 1993-03-25
DE4309737 1993-03-25

Publications (1)

Publication Number Publication Date
EP0617949A1 true EP0617949A1 (fr) 1994-10-05

Family

ID=6483849

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93117945A Withdrawn EP0617949A1 (fr) 1993-03-25 1993-11-05 Bouteille de perfusion

Country Status (2)

Country Link
EP (1) EP0617949A1 (fr)
JP (1) JPH07479A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6087283A (en) 1995-01-06 2000-07-11 Nikon Corporation Silica glass for photolithography
JPH10310394A (ja) 1997-05-15 1998-11-24 Toyota Autom Loom Works Ltd フォークリフトのティルト制御装置
JP3301416B2 (ja) * 1999-08-23 2002-07-15 株式会社豊田自動織機 産業車両におけるマスト傾動速度制御装置
EP2230297B1 (fr) * 2000-11-21 2015-03-11 Biocrystal, Ltd. Appareils de culture cellulaire et des méthodes pour son utilisation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1372589A (fr) * 1963-08-05 1964-09-18 Desjonqueres Plastiques Dispositif de bouchage pour récipients destinés à recevoir, soit du sang, soit des dérivés sanguins, soit des préparations aqueuses injectables, dont les principesactifs sont ou en solution ou en suspension
DE2327554A1 (de) * 1973-05-30 1974-12-05 Futurinvest Ag Infusionsflasche
DE2716447A1 (de) * 1977-04-14 1978-10-19 Faensen Kleinmetall Schutzkappe fuer einen eine zu sterilisierende loesung enthaltenden kunststoffbehaelter

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56119254A (en) * 1980-02-25 1981-09-18 Takeda Chemical Industries Ltd Rubber stopper for vial
JPS6131441U (ja) * 1984-07-31 1986-02-25 株式会社 大協ゴム精工 樹脂ラミネ−ト医薬品用ゴム栓
JPS62166852U (fr) * 1986-04-15 1987-10-23
JPS63134944U (fr) * 1987-02-24 1988-09-05
JPH0436902Y2 (fr) * 1987-07-06 1992-08-31

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1372589A (fr) * 1963-08-05 1964-09-18 Desjonqueres Plastiques Dispositif de bouchage pour récipients destinés à recevoir, soit du sang, soit des dérivés sanguins, soit des préparations aqueuses injectables, dont les principesactifs sont ou en solution ou en suspension
DE2327554A1 (de) * 1973-05-30 1974-12-05 Futurinvest Ag Infusionsflasche
DE2716447A1 (de) * 1977-04-14 1978-10-19 Faensen Kleinmetall Schutzkappe fuer einen eine zu sterilisierende loesung enthaltenden kunststoffbehaelter

Also Published As

Publication number Publication date
JPH07479A (ja) 1995-01-06

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