EP0336197B1 - Gezielte Abgabe dosierter Mengen von feinverteilten Feststoffen mit Venturi-Düse und geregelter Ansteuerung - Google Patents

Gezielte Abgabe dosierter Mengen von feinverteilten Feststoffen mit Venturi-Düse und geregelter Ansteuerung Download PDF

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Publication number
EP0336197B1
EP0336197B1 EP89104987A EP89104987A EP0336197B1 EP 0336197 B1 EP0336197 B1 EP 0336197B1 EP 89104987 A EP89104987 A EP 89104987A EP 89104987 A EP89104987 A EP 89104987A EP 0336197 B1 EP0336197 B1 EP 0336197B1
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EP
European Patent Office
Prior art keywords
nozzle
venturi nozzle
chamber
valve
powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP89104987A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP0336197A2 (de
EP0336197A3 (en
Inventor
Josef Dipl.-Ing. Boldis
Volker Ingo Dipl.-Chem. Gläsel
Ekkehard Dipl.-Ing. Flaischlen
Gunther M. Voss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Priority to AT89104987T priority Critical patent/ATE76790T1/de
Publication of EP0336197A2 publication Critical patent/EP0336197A2/de
Publication of EP0336197A3 publication Critical patent/EP0336197A3/de
Application granted granted Critical
Publication of EP0336197B1 publication Critical patent/EP0336197B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/0005—Details of, or accessories for, presses; Auxiliary measures in connection with pressing for briquetting presses
    • B30B15/0011—Details of, or accessories for, presses; Auxiliary measures in connection with pressing for briquetting presses lubricating means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/02—Arrangements for controlling delivery; Arrangements for controlling the spray area for controlling time, or sequence, of delivery
    • B05B12/06—Arrangements for controlling delivery; Arrangements for controlling the spray area for controlling time, or sequence, of delivery for effecting pulsating flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B12/00—Arrangements for controlling delivery; Arrangements for controlling the spray area
    • B05B12/08—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means
    • B05B12/12—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means responsive to conditions of ambient medium or target, e.g. humidity, temperature position or movement of the target relative to the spray apparatus
    • B05B12/126—Arrangements for controlling delivery; Arrangements for controlling the spray area responsive to condition of liquid or other fluent material to be discharged, of ambient medium or of target ; responsive to condition of spray devices or of supply means, e.g. pipes, pumps or their drive means responsive to conditions of ambient medium or target, e.g. humidity, temperature position or movement of the target relative to the spray apparatus responsive to target velocity, e.g. to relative velocity between spray apparatus and target
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S426/00—Food or edible material: processes, compositions, and products
    • Y10S426/811—Utilizing surface parting, antistick or release agent

Definitions

  • the invention relates to a method for the controlled removal of powdery solids according to the preamble of claim 1 and a device for carrying out the method according to the preamble of claim 9.
  • the task is to deliver powdered or finely divided solids in a targeted manner and in metered individual quantities, that is to say in the form of powder packets of a defined size, clocked to passing carriers.
  • a carrier z. B. in the food sector bakeware or chocolates in question, which are to be charged with a powdery material; in the pharmaceutical and catalyst sector, z. B. Compresses with separating layers;
  • powdered lubricants to the mechanically stressed surfaces of pressing tools for tableting granules is particularly interesting when it comes to applying this in a targeted manner to specific zones of these pressing tools but also in a quantity-defined manner.
  • US Pat. No. 4,323,530 describes a method for pressing granules into tablets, dragee cores and the like, in which a certain amount of lubricant in liquid or suspended form is applied to the stressed zones of the pressing tools by means of an intermittently operating nozzle system before each pressing operation becomes.
  • This type of lubrication allows the granules to be compressed to have no lubricant, e.g. B. magnesium stearate, more must be added; this leads, for example, to drugs with a significantly improved bioavailability of the active ingredient contained therein. Since a sparingly soluble lubricant such as a solvent such as water or lower alcohol. B.
  • magnesium stearate can only be applied to the press zones in the desired or required amount if larger volumes of these solutions are sprayed or spotted onto the surfaces, there has been a need to be able to apply such lubricants in powder form to the zones in question .
  • this type of coating with lubricants was not used in the technology of tablet production and differs fundamentally from a targeted application of lubricants to certain zones of the pressing tools but also to certain zones of carrier materials, as are common in the pharmaceutical, food or catalyst sector.
  • US Pat. No. 3,461,195 describes a device for lubricating dies using powdered lubricants. Compressed air is pressed by means of a valve in a tank filled with the powdered lubricant and the powder-air mixture is blown into a lubrication chamber on the tabletting shoe. This device is only designed for slow-running eccentric presses and cannot be transferred to modern rotary presses.
  • Japanese patent specification 20 103/73 describes the coating of the surfaces of pressing tools in tabletting machines with a powder-air mixture.
  • a powder-air mixture cone is released at the outlet openings directed onto the pressing tools and the distribution to the upper and lower punches is adjusted via a throttle valve.
  • a strong air flow is required to avoid blockages in the supply system and in the valve.
  • the resulting nebulization of the lubricant-air mixture in the area of the punches and dies, which lead to soiling not only of the pressing tools and their slide bearings but also of the tablet plate, is combated by attaching guide plates and a suction device.
  • the invention consists of a method for the controlled release of metered amounts of finely divided solids for the purpose of the targeted application of z. B. lubricants or release agents on the claimed surfaces of pressing tools in tableting machines or solids on solid substrates, eg. B. in the pharmaceutical, food or catalyst sector.
  • the features of the characterizing part of the inventive method according to claim 1 consist in that the powdery solid to be applied is first homogenized and then sucked in by means of one or more Venturi nozzles via a gaseous means of transport and transported in a targeted manner and in metered amounts to the desired passing object, for which purpose the means of transport is clocked by one or more valves in synchronism with the number of objects presented.
  • the invention also relates to an apparatus for performing the method.
  • the substance to be applied is sucked in by means of one or more Venturi nozzles through a gaseous means of transport and released through the openings of these nozzles to the object to be acted upon in a targeted and quantified manner, the means of transport being clocked by a valve in synchronism with the number of objects passed by; the venturi nozzle and the controlled activation allow the targeted and quantified release of the substances to be applied.
  • Compressed air or other gases, such as nitrogen, are suitable as gaseous means of transport.
  • the means of transport are controlled by one or more valves, the actuation of which is triggered electronically, mechanically or pneumatically.
  • the triggering of the valve or valves depends on the frequency and speed with which the objects to be charged pass the outlet openings of the venturi nozzle or nozzles.
  • sensors the approach of the pressing tools to a control device that opens the valve or valves for the means of transport at short notice, the now flowing means of transport in the venturi nozzle a defined amount of the powder-gas mixture containing the substance to be acted upon , e.g. B.
  • lubricant contains lubricant, entrained by suction and accelerated to apply this quantified mixture targeted to the areas to be acted upon.
  • the targeted application of the mixture takes place through the synchronization of the pulses and through the geometry of the nozzle openings, which, for. B. can be slit-shaped or oval or z. B. can also take the form of an eight.
  • a rotary slide valve as a valve, which bears against the inlet of the Venturi nozzle and interacts with it functionally.
  • the rotary slide valve which bears against an axis and is actuated by it in a controlled manner, serves as a compressed air valve for the venturi nozzle or nozzles, which is or are stationarily arranged directly behind the rotary slide valve.
  • the negative pressure generated by the Venturi nozzle sucks the powder-gas mixture, e.g. B. powder-air mixture, while the transport jet, z. B. air jet, the Venturi nozzle simultaneously accelerates the mixture to an outlet opening and thus in the direction of the surfaces to be acted upon.
  • the Venturi nozzle is directly in front of the surface to be acted upon, e.g. B. a dosage form, a stamp and a matrix in a tableting machine.
  • a calming zone or a calming tube behind the Venturi nozzle.
  • a deflection device can also be attached in this calming tube, which deflects the generated, pulsed beam in the direction of the objects to be acted upon.
  • a punctiform or line-shaped coating or loading of the objects can be achieved if the outlet opening is designed as a hole.
  • a square or rectangular action on the corresponding surfaces of the passing object can be achieved if the outlet opening is in the form of a gap which can be more or less elongated.
  • the compressed air for the Venturi nozzle is fed via a microdosing valve depending on the frequency and the speed at which the objects are guided past the nozzle opening, that is to say e.g. B. the tablet press.
  • a microdosing valve depending on the frequency and the speed at which the objects are guided past the nozzle opening, that is to say e.g. B. the tablet press.
  • the rotary valve takes over this task; for this purpose, the number of revolutions of the axis on which the rotary slide sits is linked to the frequency and speed at which the objects are guided past the nozzle opening.
  • the finely divided solid is processed into a homogeneous powder-gas mixture in a homogenization chamber which is connected upstream of the Venturi nozzle.
  • the preparation and homogeneous distribution of the powder particles in the gas takes place with the aid of a stirrer and / or a fluidized bed, the powder-gas mixture to be transported being passed through a sieve before being sucked into the venturi nozzle, where larger particles are caused by the action of a streamer be grated on this sieve.
  • a metering unit connected upstream of the homogenization is proportionally coupled to the number of cycles of the valve or valves in order to predose the finely divided solid, the transmission ratio, ie. H. the ratio of the throughput of the metering unit to the number of cycles of the valve, which must be adapted to the type of powder material, can be freely selected and is set individually.
  • the solid lubricant e.g. B. magnesium stearate
  • the dosing screw is driven by a motor, the revolutions of which depend on the speed of the tablet press and the desired dosing quantity.
  • the dosing screw which also makes an axial movement, transports the lubricant into a homogenization chamber e.g. B. Swirl Chamber.
  • the fluidized bed is generated by compressed air which is supplied to the bottom of the vortex chamber.
  • the amount of air to generate the fluidized bed is adjustable.
  • a motor-driven agitator in the swirl chamber prevents the formation of lumps.
  • the lubricant powder-air mixture is sucked in and accelerated, and through the outlet opening of the Venturi nozzle as a smaller or larger powder packet corresponding to the length of the air pulse the object to be loaded, here to certain zones of the punches and dies, shot down.
  • the amount of solids required for the lubrication of the pressing tools generally varying between 0.01 and 2 mg per tablet (depending on the tablet size and the type of the lubricant).
  • the pre-metering is carried out via a metering device (e.g. a micro-metering device from Gericke) which, with the aid of a stirring blade, always delivers a certain amount of the lubricant powder to a rotor which is provided with one or more grooves.
  • a metering device e.g. a micro-metering device from Gericke
  • a scraper engaging in these grooves releases the powder into a homogenization chamber; the dosage can be in wide ranges from z. B. 13 to 9600 ml / hour can be set exactly.
  • an agitator e.g. B. housed in the form of wings wound around an axis.
  • the chamber used to process the lubricant powder is delimited by a sieve at its outlet part, on which a spreader rotates, which grinds larger agglomerates; this spreader can be attached to the axis that carries the wings in the chamber, but it can also be synchronized with the frequency of the venturi nozzle. While the stirrer in this chamber prevents solids from settling and the formation of agglomerates, the spreader brushes the solid through the sieve, so it doses the powder into the adjacent space and prevents the powder from caking on the surface of the sieve.
  • the negative pressure generated by the Venturi nozzle sucks in the coated solid from the space adjacent to the underside of the sieve, while the air jet from the Venturi nozzle accelerates the solid-air mixture to the outlet openings.
  • the powder packets resulting from the clocking of the air jet reach the surfaces of the pressing tools, which have to be coated.
  • the powder is first pre-metered and fed in this form to a homogenization chamber for the preparation of a powder-gas mixture.
  • a homogenization chamber for the preparation of a powder-gas mixture.
  • an agitator for. B. in the form of inclined wings, which can also take the form of a stirring screw, the axis of this agitator being driven by a motor with a continuously variable speed.
  • an inner shaft attached in it continues to the Venturi nozzle, which is here directly coupled to a rotary slide valve; the shaft rests on the actual rotary slide element of this valve.
  • PID proportional-integral-differential
  • the agitator prevents solids from settling and the formation of agglomerates in the homogenization chamber.
  • a sieve separates the homogenization chamber from the feed into the Venturi nozzle.
  • a spreader mounted on the inner shaft sweeps the solid through the sieve and also prevents the powder from caking on the surface of the sieve.
  • the task of the agitator-spreader combination is to compensate for any fluctuations in the pre-metering and to generate a homogeneous lubricant powder-air mixture.
  • the rotary valve attached to the inner shaft after the screen serves as a compressed air valve for the venturi nozzle, which is located directly behind the rotary valve.
  • the vacuum generated by the Venturi nozzle sucks in the coated powder-gas mixture, the air jet from the Venturi nozzle accelerates the powder-gas mixture to the outlet openings and to the surfaces to be coated.
  • the invention also relates to a device for the controlled release of metered amounts of finely divided solids.
  • FIGS. 1 and 2 which in exemplary form represent a schematic cross section through the devices according to the invention.
  • FIG. 1 shows two Venturi nozzles (1), each consisting of an air nozzle A in connection with a mixing chamber B and a mixture nozzle C, suction channels (2) adjoining these Venturi nozzles, which are connected to a homogenization chamber (7) a sieve (6) are connected, a propellant line (3) connecting a valve (4) to the venturi nozzles (1), a compressed gas connection (5), a sieve (6) between the intake duct (2) and a homogenization chamber (7), a metering unit (8) connected to the latter, which can also be mounted directly in or in front of the homogenization chamber (7), a sensor (9) for generating signals in connection with a controller (10) which controls the valve (4) and actuates or regulates the manipulated variables of the metering unit (8).
  • the dosed material emerges from the mixture nozzle C as a powder-air mixture in the form of powder packets (27).
  • the venturi nozzle (1) which in turn consists of one or more air nozzles A, one or more mixing chambers B and one or more mixture nozzles C, has a rotary slide valve (11) on its inlet side, which is connected to an axis (12 ) is fixed, the axis (12) being driven by a motor M synchronously as a function of the number of nozzle openings (13) to the required speed; as an advantageous embodiment, a calming tube (14) adjoins the mixture nozzle or nozzles C, at the end of which the metered material emerges as a powder-air mixture in the form of powder packets (27) through a slot-shaped opening (15).
  • the opening (15) can be made in the extension of the axis (12), but it can also be a deflection device (16) on the axis (12) or on its own axis in the extension of the axis (12) or rigid at the end of the Sit on the calming tube (14), which deflects the dosed material at right angles.
  • a template (17) can be attached in front of the outlet opening, which ensures a geometrically modulated application of the material to the zones to be loaded.
  • the outlet opening C of the venturi nozzle can be designed as a membrane piston which, due to its inherent elasticity, can be moved axially back and forth. By moving it at regular intervals, it prevents the accumulation of disturbing deposits of the transported goods in the area of the outlet opening of the Venturi nozzle.
  • brush or wiping elements can be arranged on the axis (12) in area B of the venturi nozzle offset from the rotary slide bores (13) and in the same way in the area of the calming tube (14), which elements can be attached to the prevent goods to be transported in these areas.
  • the homogenization chamber (7) is either used with the aid of a metering roller (19) as an element of a microdosing device (e.g. device from Gericke) or a single- or twin-shaft metering screw (20) or a conveyor belt (21) or a spreader (26) with sieve (6), which serve as dosing units, are charged with the powdery material.
  • the manipulated variable of these metering units is controlled via the number of cycles of the nozzle or nozzles in such a way that the amount of powder to be introduced into the homogenization chamber (7) is in a selectable ratio to the number of cycles.
  • the homogenization chamber (7) can also be designed as a fluidized bed chamber (23) and / or have an agitator (24) suitable for homogenization;
  • the homogenization of the material can, however, also be achieved directly or alternatively by means of a suitable air duct (25).
  • the template (17) itself can form the outlet opening (15) at the end of the calming tube (14), thus representing an extension of the latter; the template (17) can also be arranged rotatably, its drive again being regulated by the controller (10) and being synchronous with the number of cycles.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Nozzles (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Jet Pumps And Other Pumps (AREA)
  • Catching Or Destruction (AREA)
  • Seal Device For Vehicle (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
EP89104987A 1988-04-02 1989-03-21 Gezielte Abgabe dosierter Mengen von feinverteilten Feststoffen mit Venturi-Düse und geregelter Ansteuerung Expired - Lifetime EP0336197B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT89104987T ATE76790T1 (de) 1988-04-02 1989-03-21 Gezielte abgabe dosierter mengen von feinverteilten feststoffen mit venturi-duese und geregelter ansteuerung.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3811260 1988-04-02
DE3811260A DE3811260A1 (de) 1988-04-02 1988-04-02 Gezielte abgabe dosierter mengen von feinverteilten feststoffen mit venturi-duese und geregelter ansteuerung

Publications (3)

Publication Number Publication Date
EP0336197A2 EP0336197A2 (de) 1989-10-11
EP0336197A3 EP0336197A3 (en) 1990-08-22
EP0336197B1 true EP0336197B1 (de) 1992-06-03

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ID=6351318

Family Applications (1)

Application Number Title Priority Date Filing Date
EP89104987A Expired - Lifetime EP0336197B1 (de) 1988-04-02 1989-03-21 Gezielte Abgabe dosierter Mengen von feinverteilten Feststoffen mit Venturi-Düse und geregelter Ansteuerung

Country Status (10)

Country Link
US (1) US5624690A (enrdf_load_stackoverflow)
EP (1) EP0336197B1 (enrdf_load_stackoverflow)
JP (1) JP2557101B2 (enrdf_load_stackoverflow)
AT (1) ATE76790T1 (enrdf_load_stackoverflow)
AU (1) AU620854B2 (enrdf_load_stackoverflow)
CA (1) CA1320915C (enrdf_load_stackoverflow)
DD (1) DD283579A5 (enrdf_load_stackoverflow)
DE (2) DE3811260A1 (enrdf_load_stackoverflow)
ES (1) ES2033036T3 (enrdf_load_stackoverflow)
GR (1) GR3005304T3 (enrdf_load_stackoverflow)

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EP1366825B1 (en) * 2002-05-28 2018-01-24 The Procter & Gamble Company Method and apparatus for creating a pulsed stream of particles
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US20080094374A1 (en) * 2006-05-05 2008-04-24 Paul Treuthardt Control device for a spreader
DE102008002311B4 (de) * 2007-10-22 2012-06-06 Korsch Ag Vorrichtung und Verfahren zum Bestäuben von Ober- und Unterstempeln einer Pulverpresse mit einem Schmier- und/oder Trennmittel sowie Pulverpresse
CN103585127A (zh) * 2008-02-28 2014-02-19 Abbvie公司 片剂和其制备方法
WO2013063288A2 (en) 2011-10-27 2013-05-02 Graco Minnesota Inc. Method and apparatus for melting
EP2771127B1 (en) 2011-10-27 2017-07-12 Graco Minnesota Inc. Sprayer fluid supply with collapsible liner
US9796492B2 (en) 2015-03-12 2017-10-24 Graco Minnesota Inc. Manual check valve for priming a collapsible fluid liner for a sprayer
JP6752034B2 (ja) * 2016-03-29 2020-09-09 株式会社菊水製作所 粉体混合度測定装置、粉体混合供給システム、圧縮成形品を製造する方法
DE102016123279B4 (de) * 2016-12-01 2019-02-21 Fette Compacting Gmbh Verfahren und System zum Zuführen eines Schmier- oder Trennmittels zu Presswerkzeugen einer Tablettenpresse
CN106827615A (zh) * 2017-03-01 2017-06-13 内蒙古包钢钢联股份有限公司 一种气动压力机
DE102018103319A1 (de) 2018-02-14 2019-08-14 Iwis Motorsysteme Gmbh & Co. Kg Metallbauteil
DE102018204440A1 (de) * 2018-03-22 2019-09-26 Glatt Maschinen- Und Apparatebau Ag Befülleinheit und Verfahren zum Befüllen von Kavitäten einer Tablettenpresse mit einem zu verpressendem Füllmaterial
CN109512674B (zh) * 2018-10-26 2021-02-12 江苏祥瑞药业有限公司 一种降血糖的盐酸二甲双胍缓释片生产设备
CN113950379B (zh) 2019-05-31 2023-09-15 固瑞克明尼苏达有限公司 手持式流体喷雾器
CN112656686B (zh) * 2020-12-19 2022-11-22 山东艾乐语健康管理有限公司 一种艾灸用艾柱制作加工工艺
DE102021128338A1 (de) 2021-10-29 2023-05-04 Romaco Innojet Gmbh Zerstäubungsdüse

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4400111C2 (de) * 1994-01-04 2003-06-18 Gunter M Voss Verfahren zur Herstellung von Tabletten

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DD283579A5 (de) 1990-10-17
DE3811260C2 (enrdf_load_stackoverflow) 1991-07-04
AU3226689A (en) 1989-10-05
DE58901567D1 (de) 1992-07-09
ES2033036T3 (es) 1993-03-01
JPH01299795A (ja) 1989-12-04
JP2557101B2 (ja) 1996-11-27
ATE76790T1 (de) 1992-06-15
US5624690A (en) 1997-04-29
AU620854B2 (en) 1992-02-27
EP0336197A2 (de) 1989-10-11
EP0336197A3 (en) 1990-08-22
DE3811260A1 (de) 1989-10-26
CA1320915C (en) 1993-08-03
GR3005304T3 (enrdf_load_stackoverflow) 1993-05-24

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