EP0294683A3 - Verfahren zur Aufnahme von ICR-Massenspektren und zur Durchführung des Verfahrens ausgebildetes ICR-Massenspektrometer - Google Patents

Verfahren zur Aufnahme von ICR-Massenspektren und zur Durchführung des Verfahrens ausgebildetes ICR-Massenspektrometer Download PDF

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Publication number
EP0294683A3
EP0294683A3 EP19880108648 EP88108648A EP0294683A3 EP 0294683 A3 EP0294683 A3 EP 0294683A3 EP 19880108648 EP19880108648 EP 19880108648 EP 88108648 A EP88108648 A EP 88108648A EP 0294683 A3 EP0294683 A3 EP 0294683A3
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EP
European Patent Office
Prior art keywords
icr mass
substances
dimensional
pulses
experiments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
EP19880108648
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English (en)
French (fr)
Other versions
EP0294683B1 (de
EP0294683A2 (de
Inventor
Geoffrey Bodenhausen
Peter Pfändler
Jacques Rapin
Tino Gäumann
Raymond Hourriet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spectrospin AG
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Spectrospin AG
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Publication date
Application filed by Spectrospin AG filed Critical Spectrospin AG
Publication of EP0294683A2 publication Critical patent/EP0294683A2/de
Publication of EP0294683A3 publication Critical patent/EP0294683A3/de
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Publication of EP0294683B1 publication Critical patent/EP0294683B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/36—Radio frequency spectrometers, e.g. Bennett-type spectrometers, Redhead-type spectrometers
    • H01J49/38—Omegatrons ; using ion cyclotron resonance

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

Die Ionen-Cyclotron-Resonanz stellt eine bedeutende Methode der Massenspektroskopie dar. Sogenannte MS/MS-Experimente erlauben auch die Beobachtung von Reaktionen der untersuch­ ten Substanzen. Diese Experimente sind jedoch sehr aufwen­ dig, weil sie selektiv für jeden der eingesetzten Stoffe und jedes einzelne der Reaktionsprodukte besonders durch­ geführt werden müssen. Die Beobachtung komplexer Vorgänge ist daher in der Praxis schwierig.
Mit Hilfe einer zweidimensionalen ICR-Methode lassen sich Reaktionen der untersuchen Substanzen feststellen, wobei die folgende Meßsequenz Anwendung findet:
P₁ - t₁ - P₂ - τm - P₃ - t₂.
Darin bedeuten P₁, P₂ und P₃ HF-Impulse, von denen die HF-Impulse P₁ und P₂ die gleiche Frequenz haben. Diese Meßsequenz wird unter Veränderung von t₁ mehrfach wieder­ holt. Auf diese Weise wird eine Vielzahl von in der Zeit t₂ aufgenommenen Induktionssignalen erhalten, die dann durch Umsetzen vom Zeitbereich in den Frequenzbereich zu einem zweidimensionalen Spektrum führen. Das Umsetzen vom Zeitbereich in den Frequenzbereich kann durch eine zwei­ dimensionale Fourier-Transformation oder nach der Methode der maximalen Entropie erfolgen.
EP88108648A 1987-06-06 1988-05-31 Verfahren zur Aufnahme von ICR-Massenspektren und zur Durchführung des Verfahrens ausgebildetes ICR-Massenspektrometer Expired - Lifetime EP0294683B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3719018 1987-06-06
DE19873719018 DE3719018A1 (de) 1987-06-06 1987-06-06 Verfahren zur aufnahme von icr-massenspektren und zur durchfuehrung des verfahrens ausgebildetes icr-massenspektrometer

Publications (3)

Publication Number Publication Date
EP0294683A2 EP0294683A2 (de) 1988-12-14
EP0294683A3 true EP0294683A3 (de) 1990-12-27
EP0294683B1 EP0294683B1 (de) 1996-10-23

Family

ID=6329213

Family Applications (1)

Application Number Title Priority Date Filing Date
EP88108648A Expired - Lifetime EP0294683B1 (de) 1987-06-06 1988-05-31 Verfahren zur Aufnahme von ICR-Massenspektren und zur Durchführung des Verfahrens ausgebildetes ICR-Massenspektrometer

Country Status (4)

Country Link
US (1) US4855593A (de)
EP (1) EP0294683B1 (de)
JP (1) JP2666147B2 (de)
DE (1) DE3719018A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4990775A (en) * 1988-06-06 1991-02-05 University Of Delaware Resolution improvement in an ion cyclotron resonance mass spectrometer
US4945234A (en) * 1989-05-19 1990-07-31 Extrel Ftms, Inc. Method and apparatus for producing an arbitrary excitation spectrum for Fourier transform mass spectrometry
US5013912A (en) * 1989-07-14 1991-05-07 University Of The Pacific General phase modulation method for stored waveform inverse fourier transform excitation for fourier transform ion cyclotron resonance mass spectrometry
US5015848A (en) * 1989-10-13 1991-05-14 Southwest Sciences, Incorporated Mass spectroscopic apparatus and method
US5047636A (en) * 1990-01-08 1991-09-10 Wisconsin Alumni Research Foundation Linear prediction ion cyclotron resonance spectrometry apparatus and method
AUPR474801A0 (en) * 2001-05-03 2001-05-31 University Of Sydney, The Mass spectrometer
EP1978374B1 (de) * 2006-01-16 2014-02-26 National University Corporation Kobe University Gasnuklearmagnetresonanzvorrichtung
GB201504934D0 (en) * 2015-03-24 2015-05-06 Micromass Ltd Improved method of FT-IMS
GB201616017D0 (en) 2016-09-20 2016-11-02 Micromass Ltd Improved method ion mobility spectrometry

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3475605A (en) * 1966-07-21 1969-10-28 Varian Associates Ion cyclotron double resonance spectrometer employing a series connection of the irradiating and observing rf sources to the cell
US3742212A (en) * 1971-02-16 1973-06-26 Univ Leland Stanford Junior Method and apparatus for pulsed ion cyclotron resonance spectroscopy
US3937955A (en) * 1974-10-15 1976-02-10 Nicolet Technology Corporation Fourier transform ion cyclotron resonance spectroscopy method and apparatus
CH656229A5 (de) * 1981-06-22 1986-06-13 Spectrospin Ag Verfahren zur ionen-zyklotron-resonanz-spektroskopie.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686365A (en) * 1984-12-24 1987-08-11 American Cyanamid Company Fourier transform ion cyclothon resonance mass spectrometer with spatially separated sources and detector
US4682027A (en) * 1986-04-25 1987-07-21 Varian Associates, Inc. Method and apparatus for sample confirmation in gas chromatography
US4761545A (en) * 1986-05-23 1988-08-02 The Ohio State University Research Foundation Tailored excitation for trapped ion mass spectrometry

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3475605A (en) * 1966-07-21 1969-10-28 Varian Associates Ion cyclotron double resonance spectrometer employing a series connection of the irradiating and observing rf sources to the cell
US3742212A (en) * 1971-02-16 1973-06-26 Univ Leland Stanford Junior Method and apparatus for pulsed ion cyclotron resonance spectroscopy
US3937955A (en) * 1974-10-15 1976-02-10 Nicolet Technology Corporation Fourier transform ion cyclotron resonance spectroscopy method and apparatus
CH656229A5 (de) * 1981-06-22 1986-06-13 Spectrospin Ag Verfahren zur ionen-zyklotron-resonanz-spektroskopie.

Also Published As

Publication number Publication date
JPH02118441A (ja) 1990-05-02
DE3719018C2 (de) 1992-04-16
EP0294683B1 (de) 1996-10-23
US4855593A (en) 1989-08-08
DE3719018A1 (de) 1988-12-22
JP2666147B2 (ja) 1997-10-22
EP0294683A2 (de) 1988-12-14

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