EP0189702A1 - Gynäkologisches Instrument, insbesondere für künstliche Befruchtung oder tierärztliche Behandlung, wie z.B. für Ferkel - Google Patents
Gynäkologisches Instrument, insbesondere für künstliche Befruchtung oder tierärztliche Behandlung, wie z.B. für Ferkel Download PDFInfo
- Publication number
- EP0189702A1 EP0189702A1 EP85402582A EP85402582A EP0189702A1 EP 0189702 A1 EP0189702 A1 EP 0189702A1 EP 85402582 A EP85402582 A EP 85402582A EP 85402582 A EP85402582 A EP 85402582A EP 0189702 A1 EP0189702 A1 EP 0189702A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- instrument according
- sheath
- substance
- reserve
- end piece
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D19/00—Instruments or methods for reproduction or fertilisation
- A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
- A61D19/027—Devices for injecting semen into animals, e.g. syringes, guns, probes
Definitions
- the invention relates to a gynecological instrument intended for the transfer of substances and more particularly for the artificial insemination of animals, in particular pigs, of the type comprising a probe consisting of an outer protective sheath in which slides a feeder duct intended for convey and expel the substance into the uterine cavity of the animal to be treated, the introduction and removal of the probe thus being done under conditions of maximum aseptic, and means of semen supply.
- Such instruments include probes already known per se and most often consisting of a tubular sheath, forming a protective sheath, serving as a guide for the probe proper consisting of a feed duct moving axially in the sheath and used to convey the substance, from a reserve, to the uterine cavity of the animal.
- probes are described in particular in the French patent of March 2, 1979 and published under the number 2,450,103 belonging to Mr. Robert CASSOU.
- the protective sheath has at its insertion end a immobilization and sealing tip, relative to which the end of the feeder duct which may be deliberately opened in its axial extension, may protrude in order to allow the spillage or the expulsion of the substance.
- This duct is slidably mounted in the sheath and is of a length greater than the latter so that it can be moved in translation relative to the sheath when it is immobilized by its end piece in the cervix of the animal.
- an inflatable balloon is provided upstream of the nozzle.
- this balloon of ovoid shape, being intended to immobilize the sheath and to be applied to the vaginal wall in order on the one hand, to constitute a tight envelope and on the other On the other hand, to provoke uterine contractions favorable to the assimilation of the substance.
- the invention therefore relates to a gynecological instrument comprising a probe essentially similar to that described above but having the enormous advantage of bringing together, under the shape of a new combination of known means, a protective outer sheath with a tip and a closed head feeder conduit allowing precise insertion and removal of the probe under perfectly sealed conditions thus avoiding any possible contact between the substance and the vaginal environment of the animal, as well as means for feeding semen.
- the instrument according to the invention is characterized in that the sheath comprises a tubular end-piece, traversed by the substance transfer duct and serving for the axial immobilization of said sheath in the cervix of the animal, the introductory end of the transfer duct being provided with a spherical head closing its section, the communication with the internal channel of the transfer duct being effected by a lateral expulsion opening situated behind the spherical head, the latter being able to take at least two positions relative to the end piece, one for closing, where it closes the passage opening of the transfer duct, the other for opening, where it is spaced from this duct to allow ejection of the substance in the uterine cavity.
- the instrument is characterized in that the tip is in particular made of flexible plastic material so as not to injure or stress the animal.
- the embodiment described below refers to the case where the substance to be transferred is semen, the instrument then serving for artificial insemination. It is obvious that this is only a nonlimiting example, the probe can just as easily be used for the delivery of treatment products such as those used for the fight against infections or infertility.
- the sheath 1 which is made of a semi-rigid material, for example PVC, has at its insertion end a tip 3, which can be crimped or glued, this tip having the particularity of being produced in the form of a spin with pitch to the left.
- This insert is preferably made of a molded plastic material chosen for its flexibility, so that the end beak 3 i which constitutes the tip of the tip 3 can follow the meanders of the mucous membranes of the vaginal cavity and especially the cervical, without injure or stress the animal.
- This protective sheath is of a length substantially shorter than the coaxial feed duct 2, as visible in FIG. 1, so that this duct can move in alternative translation in the sheath which then serves as a guide sleeve.
- the inner conduit 2 is made of a semi-rigid material, for example polypropylene, and has the double feature of comprising, on the one hand, at its introductory end, an axial closure head, on the other hand, at its rear end, markers to display the exact position of this head relative to the twisted end of the sheath.
- the introductory end of the feeder duct 2 intended to convey the seed comprises a spherical introduction head 4 which axially closes the section of the duct 2, the latter being able to communicate with the outside only through one or more radial openings 5 situated upstream of the spherical head and on the narrowed part of the latter which is connected to the diameter nominal of the duct 2.
- the positioning of the openings is essential because it allows the substance, in this case the semen, to be deposited at a precise point in the vaginal cavity, avoiding projections, of random direction, which generally occur during axial expulsions.
- This precise deposit thanks to the extension that constitutes the telescopic duct 2, has the advantage of increasing the profitability of insemination, by saving time and seed.
- the spherical head 4 can advantageously be fitted, glued or crimped onto the duct 2, but will preferably be in the axial alignment of this duct in order to avoid any roughness or deviation in diameter which may constitute an edge generating a wound.
- the feeder duct 2 passes axially through the protective sheath 1 as well as its twisted end piece 3 in order to open near the spout 3 1 , through an orifice 6 whose diameter is slightly smaller than the section of said coaxial duct 2.
- the spherical head 4 is brought back, in the position illustrated in FIG. 1, so that it closes, with sealing, the orifice 6 of the twisted endpiece, thus sheltering from any contact and especially from any contamination, the semen contained in the conduit 2, since the only openings 5, which communicate with the internal channel of this conduit, are masked by this twisted end piece.
- the diameter of the introductory head 4 is slightly greater than that of the orifice 6 in order to obtain a good seal, the elasticity of the material constituting this nozzle nevertheless allowing, a radial expansion of this orifice 6 to let said head 4 pass when it is desired to extract the conduit 2 from the sheath.
- the difference in diameter between the orifice 6 and the section of the pipe 2 causes a pinching effect which brakes the said pipe and ensures its immobilization with respect to the end piece.
- the retracted or protruding positions ( Figures 1 and 2) of the spherical head 4 assume that one can control its positioning relative to the twisted tip, when the probe is introduced into the vaginal cavity of the animal.
- the conduit 2 has a first mark 7, printed on the conduit 2, and positioned so that when the latter is in line with the rear front end 1 1 of the sheath 1, the spherical head 4 is in the closed position in the mouthpiece 3.
- the second mark 8 makes it possible to display the projecting position of the expulsion head 4 in the uterine cavity, when this said mark 8 is in turn in line with the frontal face rear 1 1 of the sheath.
- a third mark 9 can be provided corresponding to a greater insertion depth of the conduit, the pitch provided between these various marks staggered on the rear end of the conduit 2 corresponding to the different insertion depths, the rear mark making it possible to deposit the substance as far as possible from the cervix to allow insemination under optimal conditions.
- the end 2 1 of the conduit 2 is extended by a flexible connector 10, connected to a seed reserve or to a conventional syringe intended for the expulsion of said semen through the conduit 2, this connector being flexible so that it can be folded upwards to be coupled to a reserve located in a vertical plane and operating by pressure.
- the operator then proceeds to disengage the feed duct 2 by moving it axially relative to the stationary sheath, so that the spherical head 4 protrudes relative to the spout 3 1 of this nozzle as illustrated in Figure 2, the insertion depth of the conduit being defined by the pins 8 and 9 on the rear end of said conduit 2.
- This spherical head 4 will be brought as far as possible into the uterine cavity so that the expulsion semen takes place in the uterine horns so that the percentage of successful fertilization is maximum. It is desirable, for example, that the length of the feeder duct 2, which projects from the twisted end piece 3, is of the order of 20 to 40 cm, depending on the species chosen.
- the operator When the seed expulsion head is correctly positioned (this position being given by the visual references 8 or 9) the operator then ejects the semen contained in the reserve (not shown), connected to the coaxial conduit 2 by the flexible connector 10. It is useful to have recourse to a conventional syringe containing 30 to 100 cm 3 of semen and the pressure of which is sufficient to expel all of this semen.
- the coaxial feeder duct 2 is connected for its supply to a seed reserve pouch 11 having the particularity of being flexible and deformable and of being able to be fixed by simple fitting or screwing in the rear end of said duct 2.
- the pouch is formed from two blanks of food-type PVC, heat-sealed, defining a flat envelope, the base of which is provided with a flexible connection endpiece 12 capable of being coupled, as indicated previously, at the rear end of the feeder duct 2 either by force fitting using a conical nose 13 or by screwing.
- connection piece 12 is flexible so that the pocket 11 can be brought into a vertical position and thus form an angle of 90 ° relative to the axis general longitudinal view of the probe during its introduction into the vaginal cavity of the animal.
- This folding at 90 * has the effect of pinching the end piece 12 and thus closing it, thus preventing the semen contained in the pouch from being able to spill into the probe during its introduction.
- the bag is, before filling, flat and therefore free of air.
- the flexible end piece 12 is compatible with the neck of the bottles of diluent product so that it can be adapted to this neck so that the filling of the sleeve 11 is done directly by coupling the end piece 12 to said neck.
- the transfer of the diluted semen, fresh or thawed is done in an anaerobic environment, avoiding any contamination of the semen.
- the walls of the pocket 11 being deformable, the seed itself finds its place in the pocket by expansion towards the outside of the two walls.
- the pouch which is intended to receive, for example 100 ml of diluted semen, deforms only slightly so that the reserve retains a relatively thin general shape which promotes freezing and thawing of the semen.
- the versatile pouch serves both as a reserve container for freezing and defrosting the semen and as an expelling pear for the diluted semen in the body of the probe after introduction of the diluent and coupling of the probe .
- This pocket by its shape and especially due to the absence of air, allows a total expulsion of the seed and a good manual control of its expulsion.
- the quantity of semen expelled is identifiable and verifiable by means of graduations 14 printed on the pouch during its manufacture, thus making it possible to control the partial or total expulsion of the semen.
- the operator proceeds, before extraction of the probe, to withdraw the coaxial conduit 2 so as to bring it into the closed position, as illustrated in FIG. 1, the spherical head 4 then again masking the orifice 6 of the twisted end piece 3.
- the withdrawal of the conduit 2 has the effect of preventing any reflux of the seed after insemination, this closed position being defined by the visible mark 7 on the coaxial duct 2. It is only when the probe is again hermetic that we proceed, after a few minutes, to remove it, by rotating the sheath 1 in the dextrorsum direction in order to release the nozzle. twisted 3 of the cervix rings. It then suffices to carry out an axial displacement towards the rear of the probe to obtain its total withdrawal.
- the invention finds its originality in the combination of a semi-rigid sheath with a twisted tip which can be immobilized by a rotation akin to a screwing, this sheath cooperating with a feed duct also semi-rigid but whose the introductory end is closed by a spherical head which can alternatively either mask the entry of the probe, or uncover it, the position of this head being defined by visible marks on the coaxial conduit 2.
- This design thus makes it possible to obtain health protection total of the semen during the introduction of the probe, while avoiding its reflux after insemination, thanks to the ability of this material to close after expulsion.
- the examples which have just been described are not, as indicated above, limiting, and this is how the instrument can, as it is, be used, indifferently for insemination or veterinary treatment of animals.
- the telescopic duct 2 is in fact suitable for depositing medicinal products or substances for the treatment of infections or anomalies relating in particular to sterility.
- the spherical head 4 being in this case a diameter slightly greater than that of the head used with the plastic tip.
- the sheath will preferably be produced in the form of a relatively thick tube (several tenths of a millimeter) in order to oppose thermal shocks, the porous seed being particularly sensitive to temperature variations. Its opaque color will serve to protect fragile cells from the harmful effects of rays such as ultraviolet rays.
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Surgical Instruments (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8419723A FR2575063B1 (fr) | 1984-12-21 | 1984-12-21 | Sonde gynecologique pour insemination artificielle, notamment pour porcins |
FR8419723 | 1984-12-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
EP0189702A1 true EP0189702A1 (de) | 1986-08-06 |
EP0189702B1 EP0189702B1 (de) | 1989-11-02 |
Family
ID=9310925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19850402582 Expired EP0189702B1 (de) | 1984-12-21 | 1985-12-20 | Gynäkologisches Instrument, insbesondere für künstliche Befruchtung oder tierärztliche Behandlung, wie z.B. für Ferkel |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0189702B1 (de) |
DE (1) | DE3573982D1 (de) |
FR (1) | FR2575063B1 (de) |
Cited By (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2706123A1 (fr) * | 1993-06-08 | 1994-12-16 | Gestion Engineering Et | Sonde à porte-écouvillon de prélèvement à usage médical et vétérinaire. |
FR2706124A1 (fr) * | 1993-06-08 | 1994-12-16 | Gestion Engineering Et | Sonde pour l'insémination artificielle et les traitements vaginaux et utérins, et les prélèvements. |
FR2720929A1 (fr) * | 1994-06-09 | 1995-12-15 | Gestion Engineering Et | Dispositif d'insémination artificielle par gravité, notamment pour truie. |
EP0861637A1 (de) * | 1997-02-26 | 1998-09-02 | Minitüb Abfüll- und Labortechnik GmbH & Co. KG | Besamungskatheter, insbesondere für Schweine |
WO2000054700A1 (es) * | 1999-03-17 | 2000-09-21 | Santiago Martin Rillo | Canula para inseminacion artificial de ganado porcino |
FR2803189A1 (fr) | 1999-12-31 | 2001-07-06 | Imv Technologies | Dispositif d'insemination artificielle, notamment pour porcins |
WO2001049205A1 (es) * | 2000-01-03 | 2001-07-12 | Iberica De Reproduccion Asistida, S.L. | Dispositivo de inseminacion artificial en ganado porcino |
WO2001085057A1 (en) * | 2000-05-05 | 2001-11-15 | Richard Andrew Openshaw | Metering device for use in artificial insemination of an animal |
WO2002035982A2 (en) * | 2000-11-03 | 2002-05-10 | Continental Plastic Corp. | Device for trans-cervical artificial insemination and embryo transfer |
EP1066802A3 (de) * | 1999-07-09 | 2002-06-12 | Livestock Improvement Association of Japan Inc. | Gerät und Verfahren zum Injizieren von Sperma oder Embryos in ein Haustier |
ES2171128A1 (es) * | 2000-09-29 | 2002-08-16 | Iberica De Reproduccion Asisti | Equipo de inseminacion artificial post cervical en ganado porcino. |
EP1249212A1 (de) * | 2001-04-11 | 2002-10-16 | IMV Technologies | Beutel zum Verpacken von tierischem Samen und zur Behandlung vom Uterus |
ES2188351A1 (es) * | 2001-02-23 | 2003-06-16 | Magapor S L | Sistema de fabricacion de cateteres para inseminacion artificial y cateteres obtenidos. |
FR2835422A1 (fr) | 2002-02-05 | 2003-08-08 | Imv Technologies | Raccord pour un instrument gynecologique a usage veterinaire |
US7175590B2 (en) | 2001-11-01 | 2007-02-13 | Continental Plastic Corp. | Apparatus for trans-cervical artificial insemination and embryo transfer |
EP2140834A1 (de) | 2008-06-30 | 2010-01-06 | IMV Technologies | Intrauterines Transferinstrument über den natürlichen vaginal-uterinen Weg |
US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
US7723116B2 (en) | 2003-05-15 | 2010-05-25 | Xy, Inc. | Apparatus, methods and processes for sorting particles and for providing sex-sorted animal sperm |
US7772005B1 (en) | 1998-07-30 | 2010-08-10 | Xy, Llc | Method of establishing an equine artificial insemination sample |
US7820425B2 (en) | 1999-11-24 | 2010-10-26 | Xy, Llc | Method of cryopreserving selected sperm cells |
US7855078B2 (en) | 2002-08-15 | 2010-12-21 | Xy, Llc | High resolution flow cytometer |
US7929137B2 (en) | 1997-01-31 | 2011-04-19 | Xy, Llc | Optical apparatus |
US8137967B2 (en) | 2000-11-29 | 2012-03-20 | Xy, Llc | In-vitro fertilization systems with spermatozoa separated into X-chromosome and Y-chromosome bearing populations |
US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
US8497063B2 (en) | 2002-08-01 | 2013-07-30 | Xy, Llc | Sex selected equine embryo production system |
US9145590B2 (en) | 2000-05-09 | 2015-09-29 | Xy, Llc | Methods and apparatus for high purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa |
US9365822B2 (en) | 1997-12-31 | 2016-06-14 | Xy, Llc | System and method for sorting cells |
US11230695B2 (en) | 2002-09-13 | 2022-01-25 | Xy, Llc | Sperm cell processing and preservation systems |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2667504B1 (fr) * | 1990-10-09 | 1992-11-27 | Cassou Robert | Sachet-dose pour semence animale destine a l'insemination artificielle. |
FR2668054B1 (fr) * | 1990-10-19 | 1992-12-11 | Cooperative Bretonne Insem Art | Embout de sonde pour l'insemination artificielle d'animaux tels que des truies. |
US6511415B1 (en) * | 2000-11-03 | 2003-01-28 | Continental Plastic Corp. | Device for trans-cervical artificial insemination and embryo transfer |
Citations (7)
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BE497676A (de) * | 1949-08-24 | |||
US4049033A (en) * | 1974-11-21 | 1977-09-20 | Baxter Travenol Laboratories, Inc. | Molded collapsible solution container |
DE2709302A1 (de) * | 1976-11-24 | 1978-09-07 | Zeppelin Dieter Von | Katheter mit einer abdichtvorrichtung |
FR2450102A1 (fr) * | 1979-03-02 | 1980-09-26 | Cassou Robert | Dispositif d'insemination artificielle, notamment pour porcins |
EP0071538A1 (de) * | 1981-07-31 | 1983-02-09 | Bertrand Cassou | Gerät für die Verpflanzung von Elementen für die Tierfortpflanzung, wie Embrios |
FR2513111A1 (fr) * | 1981-09-23 | 1983-03-25 | Girault Francois | Prothese oesophagienne endoscopique |
US4410026A (en) * | 1981-07-13 | 1983-10-18 | Baxter Travenol Laboratories, Inc. | Port block assembly for interconnecting a fluid container with a fluid conduit |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH585550A5 (en) * | 1974-01-18 | 1977-03-15 | Abbott Lab | Drug supporting anchor - having spiral configuration for insertion into body cavities |
FR2450103A1 (fr) * | 1979-03-02 | 1980-09-26 | Cassou Robert | Perfectionnement aux dispositifs d'insemination artificielle, notamment pour porcins |
FR2556596B1 (fr) * | 1983-12-16 | 1986-12-05 | Cassou Robert | Instruments d'action gynecologique, notamment de transfert d'embryons |
-
1984
- 1984-12-21 FR FR8419723A patent/FR2575063B1/fr not_active Expired
-
1985
- 1985-12-20 DE DE8585402582T patent/DE3573982D1/de not_active Expired
- 1985-12-20 EP EP19850402582 patent/EP0189702B1/de not_active Expired
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE497676A (de) * | 1949-08-24 | |||
US4049033A (en) * | 1974-11-21 | 1977-09-20 | Baxter Travenol Laboratories, Inc. | Molded collapsible solution container |
DE2709302A1 (de) * | 1976-11-24 | 1978-09-07 | Zeppelin Dieter Von | Katheter mit einer abdichtvorrichtung |
FR2450102A1 (fr) * | 1979-03-02 | 1980-09-26 | Cassou Robert | Dispositif d'insemination artificielle, notamment pour porcins |
US4410026A (en) * | 1981-07-13 | 1983-10-18 | Baxter Travenol Laboratories, Inc. | Port block assembly for interconnecting a fluid container with a fluid conduit |
EP0071538A1 (de) * | 1981-07-31 | 1983-02-09 | Bertrand Cassou | Gerät für die Verpflanzung von Elementen für die Tierfortpflanzung, wie Embrios |
FR2513111A1 (fr) * | 1981-09-23 | 1983-03-25 | Girault Francois | Prothese oesophagienne endoscopique |
Cited By (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2706123A1 (fr) * | 1993-06-08 | 1994-12-16 | Gestion Engineering Et | Sonde à porte-écouvillon de prélèvement à usage médical et vétérinaire. |
FR2706124A1 (fr) * | 1993-06-08 | 1994-12-16 | Gestion Engineering Et | Sonde pour l'insémination artificielle et les traitements vaginaux et utérins, et les prélèvements. |
FR2720929A1 (fr) * | 1994-06-09 | 1995-12-15 | Gestion Engineering Et | Dispositif d'insémination artificielle par gravité, notamment pour truie. |
US7929137B2 (en) | 1997-01-31 | 2011-04-19 | Xy, Llc | Optical apparatus |
EP0861637A1 (de) * | 1997-02-26 | 1998-09-02 | Minitüb Abfüll- und Labortechnik GmbH & Co. KG | Besamungskatheter, insbesondere für Schweine |
US9365822B2 (en) | 1997-12-31 | 2016-06-14 | Xy, Llc | System and method for sorting cells |
US9422523B2 (en) | 1997-12-31 | 2016-08-23 | Xy, Llc | System and method for sorting cells |
US7772005B1 (en) | 1998-07-30 | 2010-08-10 | Xy, Llc | Method of establishing an equine artificial insemination sample |
WO2000054700A1 (es) * | 1999-03-17 | 2000-09-21 | Santiago Martin Rillo | Canula para inseminacion artificial de ganado porcino |
EP1066802A3 (de) * | 1999-07-09 | 2002-06-12 | Livestock Improvement Association of Japan Inc. | Gerät und Verfahren zum Injizieren von Sperma oder Embryos in ein Haustier |
US7820425B2 (en) | 1999-11-24 | 2010-10-26 | Xy, Llc | Method of cryopreserving selected sperm cells |
WO2001049206A1 (fr) * | 1999-12-31 | 2001-07-12 | Imv Technologies | Dispositif d'insemination artificielle, notamment pour porcins |
FR2803189A1 (fr) | 1999-12-31 | 2001-07-06 | Imv Technologies | Dispositif d'insemination artificielle, notamment pour porcins |
WO2001049205A1 (es) * | 2000-01-03 | 2001-07-12 | Iberica De Reproduccion Asistida, S.L. | Dispositivo de inseminacion artificial en ganado porcino |
WO2001085057A1 (en) * | 2000-05-05 | 2001-11-15 | Richard Andrew Openshaw | Metering device for use in artificial insemination of an animal |
US9145590B2 (en) | 2000-05-09 | 2015-09-29 | Xy, Llc | Methods and apparatus for high purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa |
US10208345B2 (en) | 2000-05-09 | 2019-02-19 | Xy, Llc | Method for producing high purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa |
ES2171128A1 (es) * | 2000-09-29 | 2002-08-16 | Iberica De Reproduccion Asisti | Equipo de inseminacion artificial post cervical en ganado porcino. |
WO2002035982A2 (en) * | 2000-11-03 | 2002-05-10 | Continental Plastic Corp. | Device for trans-cervical artificial insemination and embryo transfer |
WO2002035982A3 (en) * | 2000-11-03 | 2003-03-06 | Continental Plastic Corp | Device for trans-cervical artificial insemination and embryo transfer |
US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
US9879221B2 (en) | 2000-11-29 | 2018-01-30 | Xy, Llc | Method of in-vitro fertilization with spermatozoa separated into X-chromosome and Y-chromosome bearing populations |
US8652769B2 (en) | 2000-11-29 | 2014-02-18 | Xy, Llc | Methods for separating frozen-thawed spermatozoa into X-chromosome bearing and Y-chromosome bearing populations |
US7771921B2 (en) | 2000-11-29 | 2010-08-10 | Xy, Llc | Separation systems of frozen-thawed spermatozoa into X-chromosome bearing and Y-chromosome bearing populations |
US8137967B2 (en) | 2000-11-29 | 2012-03-20 | Xy, Llc | In-vitro fertilization systems with spermatozoa separated into X-chromosome and Y-chromosome bearing populations |
ES2188351A1 (es) * | 2001-02-23 | 2003-06-16 | Magapor S L | Sistema de fabricacion de cateteres para inseminacion artificial y cateteres obtenidos. |
KR100501112B1 (ko) * | 2001-04-11 | 2005-07-18 | 이엠므베 떼끄놀로지 | 동물의 정액포장 및 자궁처리를 위한 포장용구 |
US6964656B2 (en) | 2001-04-11 | 2005-11-15 | Imv Technologies | Sachet for packaging animal semen and for uterine treatment |
EP1249212A1 (de) * | 2001-04-11 | 2002-10-16 | IMV Technologies | Beutel zum Verpacken von tierischem Samen und zur Behandlung vom Uterus |
FR2823435A1 (fr) * | 2001-04-11 | 2002-10-18 | Imv Technologies | Sachet de conditionnement de semence animale et de traitement uterin |
US7175590B2 (en) | 2001-11-01 | 2007-02-13 | Continental Plastic Corp. | Apparatus for trans-cervical artificial insemination and embryo transfer |
WO2003065925A1 (fr) | 2002-02-05 | 2003-08-14 | Imv Technologies | Raccord poru un instrument gynecologique |
FR2835422A1 (fr) | 2002-02-05 | 2003-08-08 | Imv Technologies | Raccord pour un instrument gynecologique a usage veterinaire |
US8497063B2 (en) | 2002-08-01 | 2013-07-30 | Xy, Llc | Sex selected equine embryo production system |
US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
US7855078B2 (en) | 2002-08-15 | 2010-12-21 | Xy, Llc | High resolution flow cytometer |
US11230695B2 (en) | 2002-09-13 | 2022-01-25 | Xy, Llc | Sperm cell processing and preservation systems |
US11261424B2 (en) | 2002-09-13 | 2022-03-01 | Xy, Llc | Sperm cell processing systems |
US7723116B2 (en) | 2003-05-15 | 2010-05-25 | Xy, Inc. | Apparatus, methods and processes for sorting particles and for providing sex-sorted animal sperm |
EP2140834A1 (de) | 2008-06-30 | 2010-01-06 | IMV Technologies | Intrauterines Transferinstrument über den natürlichen vaginal-uterinen Weg |
Also Published As
Publication number | Publication date |
---|---|
EP0189702B1 (de) | 1989-11-02 |
DE3573982D1 (en) | 1989-12-07 |
FR2575063A1 (fr) | 1986-06-27 |
FR2575063B1 (fr) | 1988-07-01 |
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