EP0085360A2 - Elément d'étanchéité - Google Patents

Elément d'étanchéité Download PDF

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Publication number
EP0085360A2
EP0085360A2 EP83100475A EP83100475A EP0085360A2 EP 0085360 A2 EP0085360 A2 EP 0085360A2 EP 83100475 A EP83100475 A EP 83100475A EP 83100475 A EP83100475 A EP 83100475A EP 0085360 A2 EP0085360 A2 EP 0085360A2
Authority
EP
European Patent Office
Prior art keywords
cap closure
closure according
support part
support
shaped
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP83100475A
Other languages
German (de)
English (en)
Other versions
EP0085360A3 (en
EP0085360B1 (fr
Inventor
Anstalt Fur Patentverwe Gesepa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GESEPA ANSTALT fur PATENTVERWERTUNG
Original Assignee
GESEPA ANSTALT fur PATENTVERWERTUNG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19823203176 external-priority patent/DE3203176A1/de
Priority claimed from DE19823212685 external-priority patent/DE3212685A1/de
Priority claimed from DE19823239302 external-priority patent/DE3239302A1/de
Application filed by GESEPA ANSTALT fur PATENTVERWERTUNG filed Critical GESEPA ANSTALT fur PATENTVERWERTUNG
Publication of EP0085360A2 publication Critical patent/EP0085360A2/fr
Publication of EP0085360A3 publication Critical patent/EP0085360A3/de
Application granted granted Critical
Publication of EP0085360B1 publication Critical patent/EP0085360B1/fr
Expired legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the invention relates to a cap closure for a container with pharmaceutical content, in particular for bottle-shaped containers with substances intended for infusion, transfusion or injection, in which a pierceable stopper-shaped or disk-shaped sealing element is provided for sealing on the container neck, which is overlaid by a closure cap.
  • a method for producing the sealing element used is specified.
  • Cap closures for containers with pharmaceutical contents are known using metal crimp caps or welded plastic caps, for example by DE-OS 27 27 737 and DE-PS 23 27 553.
  • the bottle neck is sealed with the aid of a pierceable, disc-shaped or stopper-shaped, elastic sealing element, which is overlaid by a closure cap that can be removed in the central region and / or as a whole.
  • this closure cap is fastened to the neck of the bottle by flanging an edge bead or, in the case of plastic caps, by welding with a flange to the neck of the plastic bottle.
  • the stopper-shaped or disc-shaped sealing elements used to pre-close the bottle are made of solid rubber or a plastic with corresponding rubber-elastic properties.
  • This solid design results in a considerable waste of material of the relatively expensive elastic rubber material.
  • rubber components in particular plasticizer substances, penetrate into the container contents during the storage period, mix with it and contaminate it in the process.
  • punching the solid rubber plugs there are also stuck punch fragments that can be easily inserted into the container.
  • piercing the rubber stopper with a transfusion or injection Particles detached from the needle tip are also inserted into the container content and passed on with the container content.
  • the invention is based on the task of designing a cap closure of the type defined at the outset in such a way that the stopper-shaped or disc-shaped sealing element largely avoids the disadvantages of the known solid rubber design. There should be no significant migration of rubber constituents during the storage period, nor should the contents of the container mix with the particles that are created when closing or pushing through.
  • the cap closure with the novel sealing element should also allow simple and inexpensive largely automated mass production in the manufacture and closure of the containers.
  • the sealing element has an open support part and an elastic filler part, which is produced by injection into the support part and is firmly - preferably non-detachably - connected to it, which forms a seal against the container neck.
  • the optionally attached pierceable membrane part which is formed in one piece with the support part, in particular in the central region, prevents particles of the filling part detached from the needle tip from being inserted into the container contents and passed on with the latter.
  • the elastic support layer which the filling part can form on the membrane part, holds infusion and injection needles in place due to their clamping action.
  • a stripping effect occurs there, which keeps particles ejected from the filling part and the like away from the container contents.
  • an edge-tight holder for a piercing part is arranged on the membrane part.
  • a support layer of the filling part on the membrane part is dispensed with.
  • the piercing part which can be designed in a known manner in the form of a skewer or also as a cannula, is then held, for example, by means of a tube attachment with lip seals projecting on the inside wall.
  • the support part can have an upper cover part with a flange edge, which is connected in one piece to a cylindrical insert part. Passage recesses for injecting the filling part are advantageously provided between the upper cover part of the support part and the hollow cylindrical plug-in part.
  • the filler part forms in the cover part a middle layer overlaying the membrane part, which extends over the passage recesses from the inner cavity of the flange edge into the area of the outside of the cylindrical plug-in part and forms the sealing there against the inner wall of the container neck.
  • the support part is a disc with a protruding edge, in the middle of which there is an insert part, and that the filler part consists of an annular disc-shaped section and a cylindrical center section connected to it through passage recesses, which acts as a support layer lies on the membrane part.
  • the edge of the supporting part can be designed geometrically such that an orientation of the sealing element in a defined position is possible.
  • the edge of the support part can either be conical or be provided with other orientation approaches. This makes it possible to orient the sealing elements supplied from a storage container in such a way that the elastic sealing surface points towards the container edge when it is placed on the container. Due to the possibly appropriate covering of the annular disk-shaped section of the filling part with an elastic The covering membrane can be used to produce a disc-shaped sealing element which, after the interior of the container, only has the surfaces of the filler which are absolutely necessary for sealing.
  • the filling part forms a support layer on the membrane part
  • Puncture orientation recesses for the ring and circular surface formed by the reinforcement strips are preformed on the membrane part on the surface of the support layer of the filling part. These orientation recesses enable the targeted insertion of the transfusion needle or an additional injection needle.
  • the pulling element can expediently be designed in a ring shape, its height essentially corresponding to the thickness of the cover part enclosed by the pulling ring.
  • the pull ring practically forms the outermost edge of the lid part and can be covered with this through the crimp cap.
  • Various pharmaceutically compatible plastics are suitable as the material for the essentially dimensionally stable but not always rigid support part. Since the support part, as a dimensionally stable base body, does not have to have any significant elastic properties, it can be selected primarily from the point of view of a material which is well compatible with the contents of the container. The required elastic properties are generated by the elastic filler. A sprayable rubber compound appears to be particularly suitable for this.
  • An expedient method for producing a sealing element for a cap closure of the type described at the outset can be that the support part is injection molded in a first operation and that the elastic filler is injected into the finished support part in a subsequent second operation. This results in a favorable workflow and the desired firm anchoring of the filling part in the support part.
  • Such a further development of the manufacturing process appears to be favorable, in which the support part is formed in one mold recess of a displaceable or rotatable injection mold and in which the filler part is injected into the support part remaining after the mold has been converted, while the other part is injected Molded a support part is injected. This enables cyclical work at high working speeds.
  • a cap closure is created with a pierceable sealing element in the form of a stopper or disc, which combines favorable sealing properties with high dimensional stability and largely prevents the penetration of undesired components into the container contents.
  • the novel sealing element in which a support is partially connected to an elastic filler, which remains largely shielded from the interior of the container, excludes the impairment of the contents of the container and enables inexpensive production as a mass article.
  • FIGS. 1 and 2 show a support part 1, which consists of an upper cover part 2 with a flange edge 3 that is open on the underside and a cup-shaped end part 5, which forms part of a hollow cylindrical plug-in part 4.
  • a membrane part 6 is molded in one piece into the bottom of the end part 5.
  • the connection between the pot-shaped end part 5 and the cover part 2 is made via webs 7 which are integrally connected to both parts 2.5.
  • the lower edge of the cup-shaped end part 5 is drawn up in a conical outer part 8 up to the sealing surface which occurs when the plug is completely closed.
  • the cover part 2 is provided with injection recesses 9 through which the material of the filling part can be injected and connected to the support part 1.
  • the embodiment of the complete sealing plug essentially corresponds to FIG. 3.
  • annular reinforcement strips 10, 11 are arranged, which on the membrane part 6 have an outer annular puncture surface 12 and Define inner circular puncture surface 13.
  • Orientation recesses 15, 16 are formed in the filling part 4 (see FIG. 5). These serve to guide the infusion needle into the inner circular puncture surface 13 and to guide an injection needle into the outer circular puncture surface 12 of the membrane part 6 and thus to add additional substances into the container contents.
  • a pull-off ring 17 is integrally connected to the cover part 2 via a connecting web 18 in order to pull the closure plug out of the bottle neck.
  • the dashed position of the pull ring 17 corresponds to the position of use.
  • the height of the pull ring 17 is adapted to the thickness of the cover part 2.
  • the filling part 14 is formed as a support layer 19 on the hollow cylindrical solid insertion part 4.
  • the connection between the support layer 20 of the filling part 14 resting on the membrane part 6 and the support layer 19 is made via passage recesses 21.
  • FIG. 4 shows a support part 1 corresponding to FIG. 3, in which the membrane part 6 is not covered by a support layer of the filling part 14. Rather, in the edge region of the membrane rope 6 is a pipe bracket 22nd provided with lip seals. 23, which clamp a piercing part 24 after severing the membrane part 6 under edge sealing.
  • the bearing layer 19 of the filling part 14 is delimited in the edge region of the hollow cylindrical plug-in part 4 by an integrally molded edge strip 25.
  • the complete cap closure is shown in the embodiment of FIG. 6.
  • a prepared tear line 30 In the cover surface of the metal-tight crimp cap 28 there is a prepared tear line 30, along which a circular disk-shaped central part 31 can be pulled out with the help of a ring trigger 32.
  • the ring trigger 32 is connected to a hollow rivet 33 formed in one piece from the material of the crimp cap.
  • the disk-shaped sealing element 29 consists of the support part 1 and the rubber-elastic filler part 14.
  • the filling part 14 is made up of an annular disk-shaped section 34 and a cylindrical middle section 36 connected thereto via passage recesses 35 composed.
  • This middle piece 36 forms a support layer on the membrane part 6.
  • the sealing element consisting of an open support part and a filler part produced by injection and thereby firmly connected to this, has been explained in the preceding description as part of a cap closure.
  • the stopper-shaped design of the sealing element with or without a pull-off element attached to the edge of the cover, can, if appropriate, also be useful on its own, i.e. can be used without closing cap to close containers.
  • the overlapping closure cap can advantageously also be replaced by an open closure strip, a cover film or the like.
EP83100475A 1982-01-30 1983-01-20 Elément d'étanchéité Expired EP0085360B1 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE19823203176 DE3203176A1 (de) 1982-01-30 1982-01-30 Durchstechbarer verschlussstopfen und herstellungsverfahren hierzu
DE3203176 1982-01-30
DE19823212685 DE3212685A1 (de) 1982-04-05 1982-04-05 Kappenverschluss
DE3212685 1982-04-05
DE3239302 1982-10-23
DE19823239302 DE3239302A1 (de) 1982-10-23 1982-10-23 Verschlussstopfen mit abziehgriff

Publications (3)

Publication Number Publication Date
EP0085360A2 true EP0085360A2 (fr) 1983-08-10
EP0085360A3 EP0085360A3 (en) 1984-08-22
EP0085360B1 EP0085360B1 (fr) 1986-05-28

Family

ID=27189873

Family Applications (1)

Application Number Title Priority Date Filing Date
EP83100475A Expired EP0085360B1 (fr) 1982-01-30 1983-01-20 Elément d'étanchéité

Country Status (10)

Country Link
US (1) US4482069A (fr)
EP (1) EP0085360B1 (fr)
AR (1) AR231626A1 (fr)
AU (1) AU561490B2 (fr)
BR (1) BR8300439A (fr)
CA (1) CA1178929A (fr)
DE (1) DE3363620D1 (fr)
ES (1) ES277999Y (fr)
MX (1) MX158986A (fr)
PH (1) PH20180A (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0257498A2 (fr) * 1986-08-18 1988-03-02 Becton, Dickinson and Company Bouchon composite caoutchouc-plastique muni de joints mécaniques adhésifs
EP0320938A2 (fr) * 1987-12-16 1989-06-21 Koken Co. Ltd. Valve
WO1990000143A1 (fr) * 1988-06-28 1990-01-11 Microplast B.V. Ensemble de couvercle d'obturation et son procede de fabrication
EP0454493A2 (fr) * 1990-04-26 1991-10-30 Charles Terrence Macartney Bouchon amovible pour tubes à essais
FR2672540A1 (fr) * 1991-02-08 1992-08-14 Itw De France Bouchon pour une ouverture circulaire pratiquee dans une tole, et procede de fabrication de panneaux sandwichs utilisant ce bouchon.
EP0503330A1 (fr) * 1991-03-12 1992-09-16 SPANG & BRANDS GmbH Procédé de fabrication d'un capuchon de fermeture avec joint d'étanchéité pour bouteilles à contenu stérile et son procédé de fabrication
DE10127779A1 (de) * 2001-06-01 2002-12-12 Vetter & Co Apotheker Verschlusselement

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5328279A (en) 1984-05-22 1994-07-12 Seiko Epson Corporation Dot matrix printer head
WO1989002399A1 (fr) * 1987-09-10 1989-03-23 Joseph Parsons Nominees Pty. Ltd. Bouchon d'obturation
US5016771A (en) * 1990-09-04 1991-05-21 J. G. Finneran Associates Cap closure and liner
DE4231750C1 (de) * 1992-09-23 1994-03-10 Pohl Gmbh & Co Kg Infusionsflasche aus Kunststoff
ES2159374T3 (es) * 1995-10-18 2001-10-01 Daikyo Seiko Ltd Tapa de plastico y su procedimiento de fabricacion.
DE10127823C1 (de) * 2001-06-07 2002-08-22 West Pharm Serv Drug Res Ltd Verschluss für eine Medikamentenflasche sowie Verfahren zu dessen Herstellung
US8668400B2 (en) * 2007-04-05 2014-03-11 The Hartz Mountain Corporation Fluid applicator
US8109236B2 (en) * 2007-04-05 2012-02-07 Sumitomo Corporation Of America Fluid delivery assembly
US8967255B2 (en) * 2011-11-04 2015-03-03 Halliburton Energy Services, Inc. Subsurface release cementing plug
WO2018137760A1 (fr) * 2017-01-24 2018-08-02 Nolato Treff Ag Degersheim Récipient de réception, technique de remplissage d'un récipient de réception, procédé de transport de récipients de réception et utilisation d'un récipient de réception

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB693298A (en) * 1950-09-06 1953-06-24 William Simon Freeman Improvements in or relating to blood transfusion apparatus
FR1325077A (fr) * 1962-03-16 1963-04-26 Bouchon, en particulier pour flacon de perfusion sanguine
FR1333642A (fr) * 1962-09-18 1963-07-26 Bellignite Sa Procédé et dispositif de moulage automatique de boutons bicolores en matière plastique
CH397953A (de) * 1959-09-21 1965-08-31 Rubberfabriek Helvoet N V Behälterverschluss
DE2361350B1 (de) * 1973-12-08 1975-05-28 Matthias Faensen, Kleinmetallwarenfabrikation, 5190 Stolberg Verschluß für pharmazeutische Flaschen
DE2926008A1 (de) * 1978-06-28 1980-01-10 Hitachi Ltd Verbundformteil

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS549119B1 (fr) * 1970-09-16 1979-04-21
US3888377A (en) * 1973-05-30 1975-06-10 Reinhard Stadler Closure cap for an infusion flask
DE2727737C2 (de) * 1977-06-21 1982-07-29 Franz Pohl, Metall- und Kunststoffwarenfabrik GmbH, 7500 Karlsruhe Bördelkapsel
JPS56119254A (en) * 1980-02-25 1981-09-18 Takeda Chemical Industries Ltd Rubber stopper for vial

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB693298A (en) * 1950-09-06 1953-06-24 William Simon Freeman Improvements in or relating to blood transfusion apparatus
CH397953A (de) * 1959-09-21 1965-08-31 Rubberfabriek Helvoet N V Behälterverschluss
FR1325077A (fr) * 1962-03-16 1963-04-26 Bouchon, en particulier pour flacon de perfusion sanguine
FR1333642A (fr) * 1962-09-18 1963-07-26 Bellignite Sa Procédé et dispositif de moulage automatique de boutons bicolores en matière plastique
DE2361350B1 (de) * 1973-12-08 1975-05-28 Matthias Faensen, Kleinmetallwarenfabrikation, 5190 Stolberg Verschluß für pharmazeutische Flaschen
DE2926008A1 (de) * 1978-06-28 1980-01-10 Hitachi Ltd Verbundformteil

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0257498A2 (fr) * 1986-08-18 1988-03-02 Becton, Dickinson and Company Bouchon composite caoutchouc-plastique muni de joints mécaniques adhésifs
EP0257498A3 (en) * 1986-08-18 1988-08-03 Becton, Dickinson And Company Rubber/plastic stopper composite with mechanical adhesive joints
EP0320938A2 (fr) * 1987-12-16 1989-06-21 Koken Co. Ltd. Valve
EP0320938A3 (fr) * 1987-12-16 1990-06-13 Koken Co. Ltd. Valve
WO1990000143A1 (fr) * 1988-06-28 1990-01-11 Microplast B.V. Ensemble de couvercle d'obturation et son procede de fabrication
US5111948A (en) * 1988-06-28 1992-05-12 Microplast B.V. Cap assembly and method for producing such an assembly
EP0454493A2 (fr) * 1990-04-26 1991-10-30 Charles Terrence Macartney Bouchon amovible pour tubes à essais
EP0454493A3 (en) * 1990-04-26 1992-05-13 Charles Terrence Macartney Reinsertable closure for sample tubes
FR2672540A1 (fr) * 1991-02-08 1992-08-14 Itw De France Bouchon pour une ouverture circulaire pratiquee dans une tole, et procede de fabrication de panneaux sandwichs utilisant ce bouchon.
EP0503330A1 (fr) * 1991-03-12 1992-09-16 SPANG & BRANDS GmbH Procédé de fabrication d'un capuchon de fermeture avec joint d'étanchéité pour bouteilles à contenu stérile et son procédé de fabrication
DE10127779A1 (de) * 2001-06-01 2002-12-12 Vetter & Co Apotheker Verschlusselement
US7828777B2 (en) 2001-06-01 2010-11-09 Arzneimittel Gmbh Apotheker Vetter & Co Sealing element

Also Published As

Publication number Publication date
PH20180A (en) 1986-10-16
ES277999U (es) 1984-10-01
CA1178929A (fr) 1984-12-04
DE3363620D1 (en) 1986-07-03
MX158986A (es) 1989-04-05
ES277999Y (es) 1985-04-01
EP0085360A3 (en) 1984-08-22
AU561490B2 (en) 1987-05-07
US4482069A (en) 1984-11-13
BR8300439A (pt) 1983-11-01
EP0085360B1 (fr) 1986-05-28
AR231626A1 (es) 1985-01-31
AU1090783A (en) 1983-08-04

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