WO1989002399A1 - Bouchon d'obturation - Google Patents

Bouchon d'obturation Download PDF

Info

Publication number
WO1989002399A1
WO1989002399A1 PCT/AU1988/000353 AU8800353W WO8902399A1 WO 1989002399 A1 WO1989002399 A1 WO 1989002399A1 AU 8800353 W AU8800353 W AU 8800353W WO 8902399 A1 WO8902399 A1 WO 8902399A1
Authority
WO
WIPO (PCT)
Prior art keywords
cap
access
container
piercing
sample
Prior art date
Application number
PCT/AU1988/000353
Other languages
English (en)
Inventor
Joseph R. B. Parsons
Joanna Mary Parsons
Original Assignee
Joseph Parsons Nominees Pty. Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Joseph Parsons Nominees Pty. Ltd. filed Critical Joseph Parsons Nominees Pty. Ltd.
Publication of WO1989002399A1 publication Critical patent/WO1989002399A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs

Definitions

  • the present invention relates to a cap or closure member for a container and relates particularly but not exclusively to a cap or closure member capable of sealing the container in a substantially pressure tight manner to allow a predetermined reduced pressure to be applied to the cap and container combination to enable a fluid or fluidized sample to be drawn into the container by way of the reduced pressure.
  • the present invention also relates to a cap or closure member which enables access to the fluid sample so collected without the necessity of removing the cap from the container.
  • the present invention also relates to a cap or closure member which enables access to interior of the container by disassembling a portion of the cap.
  • the present invention most particularly relates to such a cap or cap and container such as a test or sample tube combination for obtaining and storing body fluid samples such as blood.
  • Body fluid samples such as blood are presently taken either simply by way of a standard syringe and needle or by way of a needle arrangement in which the body fluid to be sampled is withdrawn into an evacuated sample tube through needle means which pierce a stopper or cap sealing the sample tube in a substantially air tight manner.
  • cap and sample tube combinations comprise a tube sealed in a substantially airtight manner by a cap which is held on the tube by means of complementary thread means on the cap and tube or in which the cap is secured to the tube in substantially airtight manner by friction between the tube and the cap.
  • the cap in the former case is of rigid plastics material and includes an orifice to permit access via a needle to the interior of the sample tube through a resiliant synthetic or other plastics material sealing member disposed between the cap and the top of the tube.
  • a resiliant synthetic or other plastics material sealing member disposed between the cap and the top of the tube.
  • the case itself is made of, or is predominantly made of, a resilient synthetic or other plastics material.
  • This resilient cap or sealing member permits access to the evacuated sample tube by a delivery needle which permits passage of the fluid sample from a patient or other fluid sample reservoir into the sample tube under the influence of the reduced pressure in the sample tube.
  • the container must be of glass as synthetic plastic materials containers do not retain a reduced pressure over an extended period.
  • the glass containers are by their nature fragile and liable to breakage with the resultant risk of a contaminated or contagious body fluid or blood sample being accidentally spilled.
  • the degree of evacuation applied to the cap and tube combination is preset and cannot be relied on to be accurate after an extended period to draw the predetermined volume of body fluid required for subsequent processing or medical or pathological analysis.
  • the prior art caps or cap and tube combinations do not enable ready access to the sample, once collected in the sample tube, for such subsequent processing or medical or pathological analysis.
  • the cap must be removed in most cases to obtain access to the sample and thus exposes an operator to undue risk of exposure to a contaminated body fluid or blood sample as the collected sample in the tube is invariably in contact with the cap. Additionally removal of the cap increases the risk of exposure to a contaminated sample should the tube be inadvertently overturned or upset resulting in spillage of the sample.
  • Australian Patent No. 561,490 discloses a cap closure for a container having a pierceable sealing element for sealing the container neck and closing cap covering the sealing element and engageable with the container neck in which a supporting member forms a skeleton of the sealing element and an elastic filling member is injection molded and rigidly fixed to the supporting member, which cap defines a seal to seal the neck of the container.
  • Other known art of peripheral relevance is disclosed in Australian Patent Specifications 554491, 76223/81, 547866 and 500401. None of these specifications overcome the disadvantages of currently known sampling methods and apparati referred to above.
  • the present invention provides a resealable and pierceable cap or closure member adapted for co-operating with a tube to provide an enclosed space which is adapted for evacuation and/or contents storage.
  • the present invention may provide a cap having tube co-operation means, tube access means and tube sealing means. Wiping means may also be provided. Furthermore, dimple means may also be provided.
  • the present invention may alleviate capillary flow of the tube contents to the outside of the tube by providing a dimple on said cap and/or providing wiping means adjacent the access means.
  • the present invention provides, in one aspect, a cap adapted for co-operation with a container to provide a resealable enclosed space capable of evacuation to a predetermined level of reduced pressure, said cap comprising : an upper portion including a sealing member, and a lower portion including an access, said sealing member being adapted to form a reusable seal with said access so as to define said resealable enclosed space, said cap being further adapted to facilitate piercing communication with said enclosed space, after which said cap reusably seals.
  • the present invention provides, in another aspect, a cap adapted for co-operation with a container to provide a resealable enclosed space, said cap comprising : an upper portion including- a longitudinally extending portion, and a lower portion including access means and container co-operation means, said container co-operation means being adapted for abutting said container, said access means being adapted to co-operate with said longitudinally extending part, wherein in a first position, said upper and lower portions provide a sealed cap adapted for piercing access and retaining, in said tube, a vacuum or predetermined partial o vacuum for a finite period of time and wherein, in an access position, non-piercing access is provided to the enclosed space.
  • the present invention provides, in another aspect, a combination comprising a container for holding a fluidized 5 sample and a cap adapted to fit said container to form a resealable space for holding said fluidized sample, said cap comprising an upper portion and a lower portion, said portions adapted to form a reusable seal, said upper portion including a longitudinally extending member having thereon a z ⁇ substantially bulbous portion, said lower portion adapted to fit adjacent an orifice in said container, said lower portion including access means adapted to receive said extending member and forming sealing means about said bulbous portion and wiping
  • 25 means for wiping residual container contents from said extending member when said extending member is withdrawn from a sealed position in said access means, and wherein in said sealed position, a piercing apparatus can communicate with said space through said cap whereas in an
  • said extending member is in a withdrawn position from said access means thereby allowing substantially unobstructed communication with said space.
  • the present invention provides, in another aspect, a method for obtaining a first sample of a fluidized or
  • 35 fluid sample enclosed within a container fitted with a cap said method comprising the steps of : a) providing said container and said cap in a sealed position having therein said fluidized or fluid sample, b) providing sampling means for obtaining said first sample, said sampling means comprising evacuating means and piercing means, c) passing said piercing means through said cap such that an end of said piercing means is located a predetermined distance into the fluidized or fluid sample, said predetermined distance being dependent upon the size of said first sample to be obtained, d) providing said evacuating means in communication with said piercing means for obtaining or drawing said first sample through said piercing means and into said evacuating means, e) withdrawing said sampling means from said cap after said first sample is obtained.
  • the present invention provides, in still another aspect, a cap adapted for co-operation with a container, said co-operation functioning to provide an accessible space in a first use and a resealable space capable of evacuation to a predetermined level of reduced pressure in a second use, said cap comprising : an upper portion having a sealing member and being co-operable with a lower portion having an access, said sealing member and said access forming a seal during said evacuation, said lower portion, during said first use-, allowing substantially unimpeded communication to said accessible space, said cap being pierceable during said second use and upon a piercing action providing communication between an apparatus piercing said cap and said resealable space, whereupon removal of the apparatus, said cap reseals said resealable space.
  • the cap of the pres-ent invention may be made from one or more suitable materials of any type provided the material allows the cap to fulfil the function of providing a seal adapted to be pierceable.
  • the material preferably may be elastically defor able.
  • the material preferably may be silicon rubber, soft rubber or neoprene or other suitably pierceable materials.
  • FIG 1 shows one basic embodiment of the present invention.
  • FIG. 2 shows another embodiment of the present invention.
  • FIGS 3A and 3B show still another embodiment of the present invention, in unsealed and sealed configuration.
  • FIGS 4A and 4B show still another embodiment of the present invention in unsealed and sealed configuration
  • Figure 5 shows yet another embodiment of the present invention.
  • Figure 6 shows a cross-section of A-A. It is to be noted that in the figures means or features of a similar type are indicated by the same reference numeral. Also, gaps shown between upper and lower portions of the- cap in Figures 3B, 4B and 5 are only for the purpose of illustration of the components outline.
  • Fi'gure 1 shows a basic embodiment of the present invention.
  • the cap comprises an upper cap portion 11 and a lower cap portion 10.
  • the upper portion 11 includes sealing means 3 and the lower portion 10 includes access means 2 and tube co-operation means 1.
  • Tube co-operation means 1 may be adapted for co-operation or interaction with a tube.
  • the tube means 1 may be formed to fit over a tube opening, clip to the tube, push-fit to the tube, threadingly engage the tube or be of any other form such that the cap may be fixed to the tube in a manner which prevents easy removal of the cap from the tube.
  • the access means 2 may be adapted to co-operate with the sealing means 3 to provide a releasable tube seal and may be further adapted to allow access to the tube contents when the sealing means 3 is retracted from a sealing position.
  • a pipette (not shown) may be used to pass through the access means 2 and remove a sample of the tube contents from the unsealed tube.
  • the sealing means 3 may also provide a means whereby a vacuum or pressure may be retained in a tube fitted with a cap in a sealed position for a predetermined period of time.
  • the upper portion 11 may comprise a sealing means 3, which preferably, comprises a longitudinal portion
  • the sealing means 3 may be adapted to co-operate with the access means 2 in a sealing manner.
  • the lateral portion 21 may be adapted to provide an additional sealing means and/or a convenient means of removing the sealing means 3 from co-operation with the access means 2.
  • Figure 2 shows another embodiment of the present invention.
  • the tube co-operation means 1 may also include a tube mating means 8 to facilitate engagement of the cap to the tube 7.
  • the tube 7 may also include a corresponding cap mating means 9, which is adapted to also facilitate engagement of the cap to the tube 7.
  • the lower portion 10 may include a wiping means 4 associated with the access means 2.
  • the wiping means 4 may be adapted to wipe from the sealing means 3 a portion of the contents of the tube 7 that may be on the end part of the sealing means when the upper portion 11 is retracted from a sealing position. This provides a reduction in sample and/or operator or handler contamination due to exposure of the tube contents.
  • the lateral portion 21 may be adapted to be fitted into a recess in the lower portion 10, such that accidental removal of the upper portion 11 from lower portion 10 is much more difficult.
  • Upper lip 12 may provide the boundary of the recess into which the upper portion 11 is fitted into the lower portion 10 and may further provide a means for preventing accidental disengagement of the upper 11 and lower 10 portions.
  • the upper portion 11 may also include an upper sealing surface 14, and may include a bulbous portion 6, and a neck portion 15. In a sealing position, the upper portion 11 mates correspondingly with the lower portion 10, the bulbous portion 6 extending beyond access means 2, the neck portion 15 being engaged by access means 2, upper sealing surface 14 abutting lower sealing surface 13. The lateral part of upper portion 11 may be nestled within the area bounded by lip 12.
  • the bulbous portion 6 With the bulbous portion 6 extending beyond access means 2, upon sealing separation of the upper 11 and lower 10 portions, the bulbous portion 6 is pulled through access means 2 thereby wiping off tube contents from bulbous portion 6.
  • the access means 2 may also be fitted with wiping means 4 which will facilitate the wiping off of any tube contents from bulbous portion 6.
  • the tight fitting of the access means 2 around the neck portion 15 may provide a seal.
  • the longitudinal portion of the upper portion 11 may be formed larger than the access means 2 and when the upper portion is passed into the access means 2, the access means 2 expands and may thereby provide a sealingly tight grip about the longitudinal portion of the upper portion 11.
  • corresponding association of surfaces of the upper and lower portions may provide an adequate seal for a cap/tube combination.
  • the upper 11 and/or lower 10 portions may be adapted to be pierced by a suitable apparatus or means, such as a needle or syringe in order to obtain a sample of the tube contents when the upper and lower portions 11, 10 are in a sealing position.
  • the upper and lower portions may be made of any suitable material which will allow such piercing access to the tube contents and which will reseal the cap after the piercing apparatus is withdrawn from the cap.
  • suitable material may include soft rubber compounds, Silicon rubber or neoprene.
  • a cap fitted tube subjected to a vacuum or pressure should maintain substantially that vacuum or pressure for a predetermined period of time after the cap has been pierced. In other words, the cap is preferably resealably pierceable.
  • the upper portion 11 may also include one or more indentation or dimple means 5.
  • the dimple 5 may be formed such that, if the cap is pierced via the dimple 5, upon extraction of the piercing means from the capped tube, a droplet of tube contents which is invariably left on the cap's upper surface about the point of entry of the piercing means as a result of capillary action, will be held within the dimple 5.
  • the dimple 5 thereby may alleviate the possibility of an operator or tube handler coming into contact with the droplet and thereby alleviating the possibility of contamination.
  • Dimples 5 may alternately be formed such that the upper surface of upper portion 11 is substantially pitted, similar to the outer surface of a golf ball, so that retention of the droplet in a dimple 5 is enhanced if the piercing point is randomly chosen by an operator.
  • the cap may also be fitted with means to alleviate the upper and lower portions 11, 10 disengaging from a sealing position when a piercing means is retracted from the cap.
  • Figures 3A and 3B show another embodiment of the present invention.
  • Figure 3A shows the upper and lower portions of the cap in an unsealed position and
  • Figure 3B shows the upper and lower portions in a sealed position.
  • the cap shown in Figures 3A and 3B includes a tapered portion 16 on the longitudinal portion 22.
  • the tapered portion 16 can alleviate contamination by or with the tube contents, in that tube contents on the longitudinal portion 22 will tend to accumulate at the apex of tapered portion 16.
  • the apex can be wiped during separation of portions 10 and 11.
  • the cap may also include guide means 17 which provide location means fo-r the upper and lower portions 11,10 and may also provide additional sealing means and/or operation means for the upper and lower portions.
  • the cap may also include additional retention means 18 which co-operate with longitudinal portion 22, particularly the bulbous portion 6 to hold the upper portion 11 in a substantially sealed position until removal of the upper portion 11 is necessitated.
  • the retention means may comprise inwardly facing fingers or a lip or ring portion. 0
  • the retention means 18 may assist in sealing and/or wiping the upper portion 11.
  • An upwardly extending conical portion 19a may also be provided on the lower portion 10 and a corresponding conical recess portion 19b.
  • the conical portions may
  • Wiping means 4 may be provided on the end of or any other appropriate position on the access means 2 as shown in 0 Figure 3B.
  • a piercing action may be performed as aforementioned, especially if the tube is, or is to be, subjected to a pressure or vacuum. However, if the tube is not subjected to a pressure or vacuum, access may be gained
  • Non-piercing access may be provided by separating the sealing means provided by the upper and lower portions 11, 10 of the cap. For example, an operator may grasp the upper portion 11 of the cap and disengage the upper and
  • non-piercing access to the tube contents may be provided without removing the cap as a whole from the tube, only the upper portion of the cap may be temporarily withdrawn to allow access.
  • the sealing part of the cap may be adapted to be replaced in a sealing manner in order to again provide a sealed tube cap.
  • the upper and lower portions of the cap may be connected by a hinge member (20 in Figure 3B) so that the upper and lower portions of adjacent caps are not swapped, therefore avoiding sample mixing or contamination.
  • Figures 4A and 4B show a further embodiment of the present invention.
  • An upper portion 11 of mushroom type configuration is shown in Figure 4A removed from the lower portion 10.
  • This embodiment is a "push-over" tube cap, wherein the lower portion is adapted to fit over and around the top of tube 7.
  • Access means 2 is configured to substantially the configuration of the longitudinal portion 22, although substantial correlation of upper and lower portions adjacent access means 2 is not essential if an adequate closure is provided elsewhere between the upper ⁇ nd lower portion.
  • a bulbous portion 6 is adapted to fit snug / ly through access means 2. As portion 6 passes through the end of the access means, wiping means 4, preferably in the form of flaps, contact the bulbous portion so as to effect a wiping action of the end of the sealing means 3 as it is retracted from the access means 2.
  • Figure 4B shows the upper and lower portions of the cap in a sealed position.
  • Dimple 5 is shown greatly enlarged and may be contoured to substantially follow the shape of the j - longitudinal portion 22.
  • This enlarged dimple provides for greater retention of tube contents, normally left on top of a cap after piercing, out of the way of a tube handler.
  • the dimple as shown causes the walls of the longitudinal portion to be thinned. These walls may be - n thinned, in particular, more at the bulbous portion to allow easier piercing access to the interior of the tube. The walls may be thinned to such an extent that piercing access by laboratory machines can be accomplished on a capped tube.
  • Wiping means 4 although not essential to the - t - present invention, may be formed as shown in a closed position in Figure 6.
  • the longitudinal portion 22 of the upper portion 11 or a pipette or other suitable apparatus can pass 7 - through the closed fingers and thereby come into contact with the interior space of the tube/cap combination.
  • the spacing between adjacent fingers should be such that " inversion of the tube having contents therein will not allow the contents to leak out if the upper portion has been 7 - removed. This provides an added saftey feature to the present invention. Furthermore, laboratory machines can more easily probe past the fingers in order to sample the tube's contents when the upper portion 11 of the cap is removed. The fingers also reduce sample evaporation of the
  • the cap is adapted to co-operate with plastic and gloss or other composition tubes, and still provide at least some of the advantages herein disclosed.
  • FIG. 5 shows a still further embodiment, wherein
  • the lower portion 10 of the cap is formed as a "push-in" tube cap. As can be seen, the lower portion is adapted to fit snugly within the diameter of the tube 7.
  • a tapered portion or chamfer 16 may be formed on the bulbous portion to facilitate wiping of the bulbous portion when the cap is unsealed.

Abstract

Bouchon d'obturation destiné à coopérer avec un récipient afin de ménager un espace fermé rescellable se prêtant au vide jusqu'à un niveau prédéterminé de pression réduite, ledit bouchon d'obturation comprenant: une partie supérieure (11) comportant un élément d'étanchéité (3), et une partie inférieure (10) comportant un accès (2), ledit élément d'étanchéité (3) étant adapté pour former un joint réutilisable avec ledit accès (2), de manière à définir l'espace clos refermable, ledit bouchon d'obturation étant en outre adpaté pour faciliter une communication par perçage avec ledit espace fermé, après quoi ledit bouchon d'obturation ferme hermétiquement de manière réutilisable.
PCT/AU1988/000353 1987-09-10 1988-09-09 Bouchon d'obturation WO1989002399A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPI4261 1987-09-10
AU426187 1987-09-10

Publications (1)

Publication Number Publication Date
WO1989002399A1 true WO1989002399A1 (fr) 1989-03-23

Family

ID=3694709

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AU1988/000353 WO1989002399A1 (fr) 1987-09-10 1988-09-09 Bouchon d'obturation

Country Status (1)

Country Link
WO (1) WO1989002399A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0447425A1 (fr) * 1988-11-28 1991-09-25 Medix International Pty Ltd (Acn 051 838 352) Bouchon
EP0454493A2 (fr) * 1990-04-26 1991-10-30 Charles Terrence Macartney Bouchon amovible pour tubes à essais
EP0521299A2 (fr) * 1991-06-03 1993-01-07 Abbott Laboratories Recipient pour réactif et sa capsule
EP1066881A2 (fr) * 1999-07-09 2001-01-10 Becton Dickinson and Company Dispositif de prélèvement d'échantillons avec capuchon
EP1082998A2 (fr) * 1999-07-09 2001-03-14 Becton Dickinson and Company Dispositif de prélèvement d'échantillons avec capuchon
WO2001036289A1 (fr) * 1999-11-17 2001-05-25 Fredrick Michael Coory Recipient a bouchon perceur
US6562300B2 (en) 1998-08-28 2003-05-13 Becton, Dickinson And Company Collection assembly
US7854896B2 (en) 2001-09-25 2010-12-21 Becton, Dickinson And Company Closed system storage plates

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1164864B (de) * 1958-06-20 1964-03-05 Metallwerke Adolf Hopf K G Flaschenverschluss
US3167202A (en) * 1964-01-15 1965-01-26 Tolciss Joseph Closure assembly for container neck
DE2104543A1 (de) * 1971-02-01 1972-08-10 Sachau, Werner, 2842 Lohne Verschlußkappen für Wulstrandflaschen und Verfahren zu deren Herstellung
US3900028A (en) * 1974-02-26 1975-08-19 American Hospital Supply Corp Injection site for sterile medical liquid container
US4084718A (en) * 1977-02-28 1978-04-18 Varian Associates, Inc. Compression seal for elastomeric septum
AU4492679A (en) * 1978-03-31 1979-10-04 Baxter Travenol Laboratories Inc. Diagnostic reagent dispensing bottle
AU5821080A (en) * 1979-05-18 1980-11-20 Yoshino Kogyosho Co., Ltd. Container lid
AU1090783A (en) * 1982-01-30 1983-08-04 Gesepa Anstalt Fur Patentverwertung Cap closure
AU2397084A (en) * 1983-06-06 1984-12-13 Becton Dickinson & Company Closure for evacuated tube

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1164864B (de) * 1958-06-20 1964-03-05 Metallwerke Adolf Hopf K G Flaschenverschluss
US3167202A (en) * 1964-01-15 1965-01-26 Tolciss Joseph Closure assembly for container neck
DE2104543A1 (de) * 1971-02-01 1972-08-10 Sachau, Werner, 2842 Lohne Verschlußkappen für Wulstrandflaschen und Verfahren zu deren Herstellung
US3900028A (en) * 1974-02-26 1975-08-19 American Hospital Supply Corp Injection site for sterile medical liquid container
US4084718A (en) * 1977-02-28 1978-04-18 Varian Associates, Inc. Compression seal for elastomeric septum
AU4492679A (en) * 1978-03-31 1979-10-04 Baxter Travenol Laboratories Inc. Diagnostic reagent dispensing bottle
AU5821080A (en) * 1979-05-18 1980-11-20 Yoshino Kogyosho Co., Ltd. Container lid
AU1090783A (en) * 1982-01-30 1983-08-04 Gesepa Anstalt Fur Patentverwertung Cap closure
AU2397084A (en) * 1983-06-06 1984-12-13 Becton Dickinson & Company Closure for evacuated tube

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0447425A4 (en) * 1988-11-28 1993-05-19 Joseph Parsons Nominees Pty. Ltd. Cap
EP0447425A1 (fr) * 1988-11-28 1991-09-25 Medix International Pty Ltd (Acn 051 838 352) Bouchon
EP0454493A2 (fr) * 1990-04-26 1991-10-30 Charles Terrence Macartney Bouchon amovible pour tubes à essais
EP0454493A3 (en) * 1990-04-26 1992-05-13 Charles Terrence Macartney Reinsertable closure for sample tubes
EP0521299A2 (fr) * 1991-06-03 1993-01-07 Abbott Laboratories Recipient pour réactif et sa capsule
EP0521299A3 (en) * 1991-06-03 1993-02-24 Abbott Laboratories Reagent bottle and cap
US6562300B2 (en) 1998-08-28 2003-05-13 Becton, Dickinson And Company Collection assembly
EP1066881A2 (fr) * 1999-07-09 2001-01-10 Becton Dickinson and Company Dispositif de prélèvement d'échantillons avec capuchon
EP1082998A2 (fr) * 1999-07-09 2001-03-14 Becton Dickinson and Company Dispositif de prélèvement d'échantillons avec capuchon
EP1082998A3 (fr) * 1999-07-09 2002-07-03 Becton Dickinson and Company Dispositif de prélèvement d'échantillons avec capuchon
EP1066881A3 (fr) * 1999-07-09 2002-07-03 Becton Dickinson and Company Dispositif de prélèvement d'échantillons avec capuchon
WO2001036289A1 (fr) * 1999-11-17 2001-05-25 Fredrick Michael Coory Recipient a bouchon perceur
US6772910B1 (en) 1999-11-17 2004-08-10 Fredrick Michael Coory Piercing cap for a container
AU782107B2 (en) * 1999-11-17 2005-07-07 Fredrick Michael Coory Piercing cap for a container
KR100747092B1 (ko) * 1999-11-17 2007-08-07 미첼 쿠리 프레드릭 용기용 캡 및 제밀봉 가능한 용기
US7854896B2 (en) 2001-09-25 2010-12-21 Becton, Dickinson And Company Closed system storage plates

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