EG26021A - Benzoyl sulfonamide derivatives as antineoplastic - Google Patents

Benzoyl sulfonamide derivatives as antineoplastic

Info

Publication number
EG26021A
EG26021A EG2002101152A EG2002101152A EG26021A EG 26021 A EG26021 A EG 26021A EG 2002101152 A EG2002101152 A EG 2002101152A EG 2002101152 A EG2002101152 A EG 2002101152A EG 26021 A EG26021 A EG 26021A
Authority
EG
Egypt
Prior art keywords
benzoyl
antitumor agents
sulfonamide derivatives
sulfonamide
derivatives
Prior art date
Application number
EG2002101152A
Other languages
Arabic (ar)
English (en)
Inventor
دى دوس الفونس
جروسمان كوراسيى
ارثر هيبسكيند فيليب
سين لين هو.
لين لوب كارن
لويز دى جارمينديا باتريز
جوزى اديورد لوبيز
مارجريت مادر مارى
انريكو ريشيت مايكل
شيه شيوان
Original Assignee
ايلى ليلى آند كومبانى
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ايلى ليلى آند كومبانى filed Critical ايلى ليلى آند كومبانى
Application granted granted Critical
Publication of EG26021A publication Critical patent/EG26021A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/34Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EG2002101152A 2001-10-25 2002-10-21 Benzoyl sulfonamide derivatives as antineoplastic EG26021A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35201201P 2001-10-25 2001-10-25

Publications (1)

Publication Number Publication Date
EG26021A true EG26021A (en) 2012-12-10

Family

ID=23383421

Family Applications (1)

Application Number Title Priority Date Filing Date
EG2002101152A EG26021A (en) 2001-10-25 2002-10-21 Benzoyl sulfonamide derivatives as antineoplastic

Country Status (33)

Country Link
US (2) US7084170B2 (OSRAM)
EP (1) EP1442030B1 (OSRAM)
JP (1) JP4464681B2 (OSRAM)
KR (1) KR100913471B1 (OSRAM)
CN (1) CN1298709C (OSRAM)
AR (1) AR037248A1 (OSRAM)
AT (1) ATE338033T1 (OSRAM)
AU (1) AU2002334817B2 (OSRAM)
BR (1) BR0212386A (OSRAM)
CA (1) CA2463300C (OSRAM)
CY (1) CY1106247T1 (OSRAM)
DE (1) DE60214413T2 (OSRAM)
DK (1) DK1442030T3 (OSRAM)
EA (1) EA006081B1 (OSRAM)
EC (1) ECSP045078A (OSRAM)
EG (1) EG26021A (OSRAM)
ES (1) ES2269816T3 (OSRAM)
HR (1) HRP20040371B1 (OSRAM)
HU (1) HUP0401638A3 (OSRAM)
IL (2) IL160851A0 (OSRAM)
MX (1) MXPA04003886A (OSRAM)
MY (1) MY130718A (OSRAM)
NO (1) NO20041316L (OSRAM)
NZ (1) NZ531136A (OSRAM)
PE (1) PE20030574A1 (OSRAM)
PL (1) PL208083B1 (OSRAM)
PT (1) PT1442030E (OSRAM)
SI (1) SI1442030T1 (OSRAM)
SV (1) SV2004001367A (OSRAM)
TW (1) TWI281916B (OSRAM)
UA (1) UA75716C2 (OSRAM)
WO (1) WO2003035629A1 (OSRAM)
ZA (1) ZA200403089B (OSRAM)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA007484B1 (ru) * 2001-06-11 2006-10-27 Вирокем Фарма Инк. Соединения и способы лечения или предупреждения инфекций flavivirus
SE0102616D0 (sv) * 2001-07-25 2001-07-25 Astrazeneca Ab Novel compounds
WO2003104218A1 (en) * 2002-06-06 2003-12-18 Smithkline Beecham Corporation Nf-:b inhibitors
PT1569929E (pt) 2002-12-10 2010-06-18 Virochem Pharma Inc Compostos e métodos para o tratamento ou prevenção de infecções por flavivírus
SE0300091D0 (sv) * 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
SE0300092D0 (sv) * 2003-01-15 2003-01-15 Astrazeneca Ab Novel compounds
US20050085531A1 (en) * 2003-10-03 2005-04-21 Hodge Carl N. Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
JP5134247B2 (ja) * 2004-09-13 2013-01-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド含有化合物の血管新生阻害物質との併用
WO2006030947A1 (ja) * 2004-09-13 2006-03-23 Eisai R & D Management Co., Ltd. スルホンアミド含有化合物の血管新生阻害物質との併用
US8772269B2 (en) 2004-09-13 2014-07-08 Eisai R&D Management Co., Ltd. Use of sulfonamide-including compounds in combination with angiogenesis inhibitors
CN101232901B (zh) * 2005-02-28 2011-12-07 卫材R&D管理有限公司 磺酰胺化合物和血管生成抑制物质的联合新应用
WO2006090921A1 (ja) * 2005-02-28 2006-08-31 Eisai R & D Management Co., Ltd. スルホンアミド化合物のリンパ球活性化抑制作用
US20090047278A1 (en) 2005-02-28 2009-02-19 Eisai R & D Management Co., Ltd. Novel Combinational Use of Sulfonamide Compound
NZ563909A (en) * 2005-05-13 2011-10-28 Virochem Pharma Inc Thiophene derivatives and their use for the treatment or prevention of flavivirus infections
US7208506B2 (en) * 2005-07-07 2007-04-24 Hoffmann-La Roche Inc. Heteroarylethenyl derivatives, their manufacture and use as pharmaceutical agents
US7625896B2 (en) * 2005-11-25 2009-12-01 Hoffman-La Roche Inc. Pyridylsulfonamide derivatives
US20100291592A1 (en) 2006-04-20 2010-11-18 Taro Semba Novel marker for sensitivity against sulfonamide compound
US7939532B2 (en) 2006-10-26 2011-05-10 Hoffmann-La Roche Inc. Heterocyclyl pyridyl sulfonamide derivatives, their manufacture and use as pharmaceutical agents
NZ576780A (en) 2006-11-15 2011-12-22 Virochem Pharma Inc Thiophene analogues for the treatment or prevention of flavivirus infections
JP2010526844A (ja) 2007-05-16 2010-08-05 エフ.ホフマン−ラ ロシュ アーゲー アリールピリジルスルホンアミド誘導体、それらの製造法及び医薬剤としての使用
CN101899008B (zh) * 2010-05-20 2012-10-17 中国人民解放军第二军医大学 N-取代嘧啶磺酰基-取代苯甲酰胺类化合物及其制备药物的用途
CN103450149B (zh) * 2012-06-01 2015-10-14 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物及其制备方法和用途
JP6364967B2 (ja) * 2014-05-30 2018-08-01 東ソー株式会社 ジチエノベンゾジチオフェンの製造方法
CN106588868A (zh) * 2016-11-16 2017-04-26 武汉理工大学 一种2‑溴‑3‑噻吩甲酸中间体的合成方法
CN108558822B (zh) * 2018-06-01 2020-12-18 盐城锦明药业有限公司 N-((5-溴噻吩-2-基)磺酰基)-2,4-二氯苯甲酰胺的合成方法
CN110835345A (zh) * 2018-08-17 2020-02-25 中国科学院上海药物研究所 一类细胞周期依赖性激酶的降解剂、其制备方法、药物组合物及其用途
CN109265437A (zh) * 2018-10-19 2019-01-25 凯莱英医药集团(天津)股份有限公司 一种3-羟基噻吩-2-羧酸酯类化合物的制备方法
WO2024251876A1 (en) * 2023-06-07 2024-12-12 KRæFTENS BEKæMPELSE PROTACs AND HyT-PD MOLECULES FOR TARGETED PROTEIN DEGRADATION OF DCAF15 AND THEIR USE IN THE TREATMENT OF AMYLOIDOSIS
WO2025031360A1 (zh) * 2023-08-09 2025-02-13 上海科技大学 磺酰胺类化合物及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA813332B (en) * 1980-06-21 1982-05-26 Pfizer Larvicides and isecticides
NZ238911A (en) * 1990-07-17 1993-10-26 Lilly Co Eli Furyl, pyrrolyl and thienyl sulphonyl urea derivatives, pharmaceutical compositions and intermediates therefor
US5177074A (en) * 1991-03-26 1993-01-05 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted thiophene or furan
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment
AU737038B2 (en) * 1996-07-05 2001-08-09 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Anti-viral pharmaceutical compositions containing saturated 1,2-dithiaheterocyclic compounds and uses thereof
AU4799797A (en) * 1996-10-04 1998-04-24 Eli Lilly And Company Antitumor compositions and methods of treatment
JP4316787B2 (ja) 2000-01-11 2009-08-19 壽製薬株式会社 エーテル又はアミド誘導体、その製法並びにそれを含有する糖尿病治療剤、

Also Published As

Publication number Publication date
ZA200403089B (en) 2005-04-22
NO20041316L (no) 2004-03-30
CN1575286A (zh) 2005-02-02
EA006081B1 (ru) 2005-08-25
DK1442030T3 (da) 2006-12-27
DE60214413T2 (de) 2007-03-08
HRP20040371B1 (en) 2012-07-31
JP4464681B2 (ja) 2010-05-19
AR037248A1 (es) 2004-11-03
NZ531136A (en) 2006-08-31
CA2463300A1 (en) 2003-05-01
DE60214413D1 (de) 2006-10-12
ECSP045078A (es) 2004-06-28
EP1442030A1 (en) 2004-08-04
HUP0401638A3 (en) 2012-09-28
ES2269816T3 (es) 2007-04-01
MXPA04003886A (es) 2004-07-08
KR100913471B1 (ko) 2009-08-25
JP2005511547A (ja) 2005-04-28
US20040198784A1 (en) 2004-10-07
BR0212386A (pt) 2004-07-27
WO2003035629A1 (en) 2003-05-01
UA75716C2 (en) 2006-05-15
HUP0401638A2 (hu) 2004-11-29
PT1442030E (pt) 2006-12-29
SV2004001367A (es) 2004-02-24
EA200400582A1 (ru) 2004-08-26
IL160851A (en) 2009-11-18
PE20030574A1 (es) 2003-07-03
PL368234A1 (en) 2005-03-21
HK1068337A1 (en) 2005-04-29
AU2002334817B2 (en) 2008-02-21
HRP20040371A2 (en) 2004-08-31
IL160851A0 (en) 2004-08-31
CA2463300C (en) 2011-07-19
US20060223871A1 (en) 2006-10-05
TWI281916B (en) 2007-06-01
ATE338033T1 (de) 2006-09-15
US7084170B2 (en) 2006-08-01
KR20040062583A (ko) 2004-07-07
EP1442030B1 (en) 2006-08-30
CN1298709C (zh) 2007-02-07
MY130718A (en) 2007-07-31
CY1106247T1 (el) 2011-06-08
PL208083B1 (pl) 2011-03-31
SI1442030T1 (sl) 2006-12-31
US7250430B2 (en) 2007-07-31

Similar Documents

Publication Publication Date Title
EG26021A (en) Benzoyl sulfonamide derivatives as antineoplastic
ZA200309522B (en) Substituted cyclohexane-1-4diamine derivatives
PL368816A1 (en) 3-substituted-4-pyrimidone derivatives
EP1349502A4 (en) PISIOTOMY ENGINE
IL158388A0 (en) Novel arylheteroalkylamine derivatives
GB0119062D0 (en) Interferometer
DE60215145D1 (en) Sulfonamide
HUP0303449A3 (en) Substituted benzofuran-2-carboxamides derivatives
HUP0400345A3 (en) Antiviral phosphono-pyrimidine derivatives
HUP0401949A3 (en) 4-imidazolin-2-one derivatives
HUP0303186A3 (en) 4-aminobenzopyran derivatives
HUP0500026A3 (en) N-heteroarylnicotinamide derivatives
PL358184A1 (en) Sulfonamide derivatives
IL159064A0 (en) New phenylalkyloxy- phenyl derivatives
IL162443A (en) Imidazoquinoline derivatives
EP1364954A4 (en) Dicarba closo DODECARBORANDERIVATE
PL358180A1 (en) Sulfonamide derivatives
AU2003269950A1 (en) Heteroaryl-ethanolamine derivatives as antiviral agents
AU2003304151A8 (en) Heteroaryl-ethanolamine derivatives as antiviral agents
AU2003265385A1 (en) Aryl-ethanolamine derivatives as antiviral agents
GB0103065D0 (en) Interferometer
AU2002243848A1 (en) Substituted quinolinecarboxamides as antiviral agents
AUPR775601A0 (en) Antiviral agents
AU2002302509A1 (en) Arylsulfonamides as antiviral agents
GB0103066D0 (en) Interferometer