EG23802A - 2-Phenylpyran-4-one derivatives - Google Patents

2-Phenylpyran-4-one derivatives

Info

Publication number
EG23802A
EG23802A EG118999A EG118999A EG23802A EG 23802 A EG23802 A EG 23802A EG 118999 A EG118999 A EG 118999A EG 118999 A EG118999 A EG 118999A EG 23802 A EG23802 A EG 23802A
Authority
EG
Egypt
Prior art keywords
phenylpyran
derivatives
Prior art date
Application number
EG118999A
Other languages
English (en)
Inventor
Maria I Crespo
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES9802011A external-priority patent/ES2154561B1/es
Priority claimed from ES009900619A external-priority patent/ES2168895A1/es
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Application granted granted Critical
Publication of EG23802A publication Critical patent/EG23802A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/24Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/38Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
EG118999A 1998-09-25 1999-09-25 2-Phenylpyran-4-one derivatives EG23802A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES9802011A ES2154561B1 (es) 1998-09-25 1998-09-25 Derivados de 2-fenilpiran-4-ona.
ES009900619A ES2168895A1 (es) 1999-03-26 1999-03-26 Derivados de 2-fenilpiran-4-ona.

Publications (1)

Publication Number Publication Date
EG23802A true EG23802A (en) 2007-08-22

Family

ID=26155180

Family Applications (1)

Application Number Title Priority Date Filing Date
EG118999A EG23802A (en) 1998-09-25 1999-09-25 2-Phenylpyran-4-one derivatives

Country Status (34)

Country Link
US (1) US6518303B2 (fr)
EP (1) EP1115716B1 (fr)
JP (1) JP4717211B2 (fr)
KR (1) KR100806684B1 (fr)
CN (1) CN1202104C (fr)
AR (1) AR021826A1 (fr)
AT (1) ATE230405T1 (fr)
AU (1) AU765653B2 (fr)
BG (1) BG65308B1 (fr)
BR (1) BR9913939A (fr)
CA (1) CA2345069C (fr)
CO (1) CO5140127A1 (fr)
CZ (1) CZ300357B6 (fr)
DE (1) DE69904738T2 (fr)
DK (1) DK1115716T3 (fr)
EE (1) EE04812B1 (fr)
EG (1) EG23802A (fr)
ES (1) ES2190252T3 (fr)
HK (1) HK1034961A1 (fr)
HU (1) HUP0104620A3 (fr)
ID (1) ID28624A (fr)
IL (1) IL142087A0 (fr)
MX (1) MXPA01003069A (fr)
MY (1) MY121793A (fr)
NO (1) NO327987B1 (fr)
NZ (1) NZ510625A (fr)
PE (1) PE20001067A1 (fr)
PL (1) PL346895A1 (fr)
RU (1) RU2232158C2 (fr)
SI (1) SI1115716T1 (fr)
SK (1) SK286471B6 (fr)
TR (1) TR200100852T2 (fr)
TW (1) TW587079B (fr)
WO (1) WO2000018753A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20011333A1 (es) * 2000-03-16 2002-01-16 Almirall Prodesfarma Ag Derivados de 2-fenilpiran-4-ona como inhibidores de ciclooxigenasa 2
US20040147581A1 (en) * 2002-11-18 2004-07-29 Pharmacia Corporation Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
ES2214130B1 (es) * 2003-02-13 2005-12-01 Almirall Prodesfarma, S.A. 2-3'-bipiridinas.
ES2214129B1 (es) * 2003-02-13 2005-12-01 Almirall Prodesfarma, S.A. 3-fenilfuran-2-onas.
ES2213485B1 (es) * 2003-02-13 2005-12-16 Almirall Prodesfarma, S.A. Derivados de la 2-fenilpiran-4-ona.
US20040220155A1 (en) * 2003-03-28 2004-11-04 Pharmacia Corporation Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
WO2005009342A2 (fr) * 2003-07-16 2005-02-03 Pharmacia Corporation Methode de traitement ou de prevention de troubles dermatologiques a l'aide d'un seul inhibiteur de la cyclooxygenase-2 ou en combinaison avec un agent de traitement dermatologique, et compositions contenant ceux-ci
US20050119262A1 (en) * 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
US20050107350A1 (en) * 2003-08-22 2005-05-19 Pharmacia Corporation Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
WO2005023189A2 (fr) * 2003-09-03 2005-03-17 Pharmacia Corporation Procede de prevention ou de traitement de la douleur, de l'inflammation, et de troubles lies a l'inflammation avec un inhibiteur selectif de cox-2 en combinaison avec un agent donneur de monoxyde d'azote et compositions en contenant
IL305573A (en) 2021-03-15 2023-10-01 Saul Yedgar Hyaluronic acid conjugated with dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment or suppression of inflammatory diseases

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US304728A (en) * 1884-09-09 Maubice hellwig
CH523257A (de) * 1969-12-31 1972-05-31 Ciba Geigy Ag Verfahren zur Herstellung von neuen Imidazolderivaten
US3901908A (en) * 1970-12-28 1975-08-26 Ciba Geigy Corp 2-alkyl- and 2-cycloalkyl-4,5-bis-phenyl-imidazoles
IL59748A (en) 1979-04-05 1983-11-30 Lilly Industries Ltd 5-substituted pyranone derivatives,their production and pharmaceutical compositions containing them
US4304728A (en) * 1979-04-05 1981-12-08 Lilly Industries Limited 6-Substituted pyranone compounds and their use as pharmaceuticals
JPS5834446B2 (ja) * 1979-05-22 1983-07-27 三省製薬株式会社 消炎剤
JPH0768234B2 (ja) * 1989-12-14 1995-07-26 久光製薬株式会社 コウジ酸エステル誘導体
KR920702353A (ko) * 1990-06-29 1992-09-03 로버트 에이. 아미테이지 아테롬성 동맥경화증 및 혈전등 치료제인 2-아미노-6-페닐-4h-피란-4-온
JPH04173391A (ja) * 1990-11-07 1992-06-22 Sanyo Chem Ind Ltd 感熱記録用増感剤および感熱記録用材料
DE4103904C2 (de) * 1991-02-08 1995-06-14 Analyticon Ges Fuer Chemische Neue Arzneimittel aus Gamma-Pyronen, Gamma-Pyridonen sowie Gamma-Thiopyronen
US6048850A (en) 1992-09-22 2000-04-11 Young; Donald A. Method of inhibiting prostaglandin synthesis in a human host
RU2153497C2 (ru) * 1993-11-19 2000-07-27 Парк,Дэвис Энд Компани Производные пирона, фармацевтическая композиция с антивирусной и антибактериальной активностью на их основе и способ лечения вызванных ретровирусом инфекции или заболевания
US5521213A (en) * 1994-08-29 1996-05-28 Merck Frosst Canada, Inc. Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
US5541204A (en) 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
NZ304886A (en) 1995-04-04 1998-11-25 Glaxo Group Ltd Imidazo [1,2a] pyridine derivatives, preparation and pharmaceutical compositions thereof
EP0833622B8 (fr) * 1995-06-12 2005-10-12 G.D. Searle & Co. Compositions comprenant un inhibiteur de cyclooxygenase-2 et un inhibiteur de 5-lipoxygenase
CA2307111C (fr) * 1997-11-19 2009-06-30 Kowa Co., Ltd. Nouveaux derives de pyridazine et medicaments contenant ces composes comme principe actif

Also Published As

Publication number Publication date
AR021826A1 (es) 2002-08-07
CN1324352A (zh) 2001-11-28
NZ510625A (en) 2002-12-20
WO2000018753A1 (fr) 2000-04-06
JP2002525364A (ja) 2002-08-13
NO20011512L (no) 2001-05-25
PL346895A1 (en) 2002-03-11
CN1202104C (zh) 2005-05-18
ID28624A (id) 2001-06-21
PE20001067A1 (es) 2000-10-23
EP1115716A1 (fr) 2001-07-18
DE69904738D1 (de) 2003-02-06
NO20011512D0 (no) 2001-03-23
MXPA01003069A (es) 2002-07-02
CZ300357B6 (cs) 2009-04-29
EE04812B1 (et) 2007-04-16
AU6084799A (en) 2000-04-17
CA2345069C (fr) 2009-03-10
SK3702001A3 (en) 2001-12-03
HUP0104620A2 (hu) 2002-04-29
DK1115716T3 (da) 2003-02-24
MY121793A (en) 2006-02-28
RU2232158C2 (ru) 2004-07-10
TW587079B (en) 2004-05-11
BR9913939A (pt) 2001-06-12
CZ20011058A3 (cs) 2001-08-15
ATE230405T1 (de) 2003-01-15
JP4717211B2 (ja) 2011-07-06
TR200100852T2 (tr) 2001-10-22
EP1115716B1 (fr) 2003-01-02
US6518303B2 (en) 2003-02-11
KR100806684B1 (ko) 2008-02-26
HUP0104620A3 (en) 2003-01-28
CO5140127A1 (es) 2002-03-22
HK1034961A1 (en) 2001-11-09
KR20010075369A (ko) 2001-08-09
NO327987B1 (no) 2009-11-02
SK286471B6 (sk) 2008-11-06
IL142087A0 (en) 2002-03-10
EE200100173A (et) 2002-08-15
ES2190252T3 (es) 2003-07-16
US20020045644A1 (en) 2002-04-18
CA2345069A1 (fr) 2000-04-06
SI1115716T1 (en) 2003-06-30
DE69904738T2 (de) 2003-04-30
BG65308B1 (bg) 2008-01-31
AU765653B2 (en) 2003-09-25
BG105373A (en) 2001-11-30

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