EG17342A - A process for preparing indoline and 2-indelinone derivatives - Google Patents
A process for preparing indoline and 2-indelinone derivativesInfo
- Publication number
- EG17342A EG17342A EG296/85D EG29685D EG17342A EG 17342 A EG17342 A EG 17342A EG 296/85 D EG296/85 D EG 296/85D EG 29685 D EG29685 D EG 29685D EG 17342 A EG17342 A EG 17342A
- Authority
- EG
- Egypt
- Prior art keywords
- indelinone
- derivatives
- indoline
- preparing
- preparing indoline
- Prior art date
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61021084A | 1984-05-14 | 1984-05-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EG17342A true EG17342A (en) | 1991-03-30 |
Family
ID=24444125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EG296/85D EG17342A (en) | 1984-05-14 | 1985-05-12 | A process for preparing indoline and 2-indelinone derivatives |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0161918B1 (pm) |
| JP (1) | JPH0643417B2 (pm) |
| KR (1) | KR870000274B1 (pm) |
| AR (1) | AR241531A1 (pm) |
| AT (1) | ATE54915T1 (pm) |
| AU (1) | AU577372B2 (pm) |
| CA (1) | CA1248099A (pm) |
| DE (1) | DE3578822D1 (pm) |
| DK (1) | DK207785A (pm) |
| EG (1) | EG17342A (pm) |
| ES (1) | ES8609308A1 (pm) |
| GR (1) | GR851121B (pm) |
| HU (1) | HU194873B (pm) |
| IL (1) | IL75122A (pm) |
| MY (1) | MY101520A (pm) |
| NZ (1) | NZ212023A (pm) |
| PH (1) | PH21862A (pm) |
| PT (1) | PT80414B (pm) |
| SU (1) | SU1486060A3 (pm) |
| ZA (1) | ZA853440B (pm) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4591591A (en) * | 1984-03-08 | 1986-05-27 | Eli Lilly And Company | Pyridazinone derivatives as inotropic agents |
| DE3631085A1 (de) * | 1986-09-12 | 1988-03-24 | Boehringer Mannheim Gmbh | Heterocyclisch substituierte indolinone, verfahren zu ihrer herstellung, arzneimittel sowie zwischenprodukte |
| DE3706427A1 (de) * | 1987-02-27 | 1988-09-08 | Boehringer Mannheim Gmbh | Neue substituierte 3h-indole, zwischenprodukte, verfahren zu ihrer herstellung sowie arzneimittel |
| DE3871464D1 (de) * | 1987-08-28 | 1992-07-02 | Lilly Co Eli | Die permeation verbessernde zusammensetzung. |
| US5196416A (en) * | 1987-08-28 | 1993-03-23 | Eli Lilly And Company | Transdermal flux-enhancing pharmaceutical compositions comprising azone, ethanol and water |
| EP0326307B1 (en) * | 1988-01-23 | 1994-08-17 | Kyowa Hakko Kogyo Co., Ltd. | Novel pyridazinone derivatives and pharmaceutical preparations containing them |
| GB8816944D0 (en) * | 1988-07-15 | 1988-08-17 | Sobio Lab | Compounds |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2688161C (en) | 2007-06-04 | 2020-10-20 | Kunwar Shailubhai | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP2810951B1 (en) | 2008-06-04 | 2017-03-15 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| EP3366698A1 (en) | 2011-03-01 | 2018-08-29 | Synergy Pharmaceuticals Inc. | Guanylate cyclase c agonists |
| CA2902348C (en) | 2013-02-25 | 2021-11-30 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
| SI3004138T1 (sl) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Limited | Ultra čisti agonisti gvanilat ciklaze C, postopek za njihovo pripravo in uporabo |
| IL280864B2 (en) | 2013-08-09 | 2024-03-01 | Ardelyx Inc | Compounds and methods for inhibiting phosphate transport |
| EP3972599A1 (en) | 2019-05-21 | 2022-03-30 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
| US20240308973A1 (en) * | 2023-03-10 | 2024-09-19 | Zoetis Services Llc | Phosphodiesterase 3 (pde3) inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES482789A0 (es) * | 1978-08-25 | 1980-12-01 | Thomae Gmbh Dr K | Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona |
| US4258185A (en) * | 1978-10-17 | 1981-03-24 | Yoshitomi Pharmaceutical Industries, Ltd. | Pyridazinone compounds |
| DE3124699A1 (de) * | 1981-06-24 | 1983-01-13 | Basf Ag, 6700 Ludwigshafen | Neue 2-aryl-3,4-diaza-bicyclo(4.n.0.)alken-(2)-one-(5),verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| JPS588016A (ja) * | 1981-07-06 | 1983-01-18 | Mitsubishi Chem Ind Ltd | 強心剤 |
-
1985
- 1985-05-07 IL IL75122A patent/IL75122A/xx unknown
- 1985-05-07 ZA ZA853440A patent/ZA853440B/xx unknown
- 1985-05-07 CA CA000480903A patent/CA1248099A/en not_active Expired
- 1985-05-08 GR GR851121A patent/GR851121B/el unknown
- 1985-05-08 PT PT80414A patent/PT80414B/pt not_active IP Right Cessation
- 1985-05-09 NZ NZ212023A patent/NZ212023A/en unknown
- 1985-05-09 AR AR85300328A patent/AR241531A1/es active
- 1985-05-09 PH PH32245A patent/PH21862A/en unknown
- 1985-05-10 DE DE8585303310T patent/DE3578822D1/de not_active Expired - Lifetime
- 1985-05-10 DK DK207785A patent/DK207785A/da not_active Application Discontinuation
- 1985-05-10 EP EP85303310A patent/EP0161918B1/en not_active Expired - Lifetime
- 1985-05-10 AT AT85303310T patent/ATE54915T1/de not_active IP Right Cessation
- 1985-05-12 EG EG296/85D patent/EG17342A/xx active
- 1985-05-13 SU SU853911552A patent/SU1486060A3/ru active
- 1985-05-13 AU AU42405/85A patent/AU577372B2/en not_active Ceased
- 1985-05-13 JP JP60102499A patent/JPH0643417B2/ja not_active Expired - Lifetime
- 1985-05-13 HU HU851801A patent/HU194873B/hu not_active IP Right Cessation
- 1985-05-13 ES ES543078A patent/ES8609308A1/es not_active Expired
- 1985-05-14 KR KR1019850003271A patent/KR870000274B1/ko not_active Expired
-
1987
- 1987-09-22 MY MYPI87001859A patent/MY101520A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR241531A1 (es) | 1992-08-31 |
| EP0161918B1 (en) | 1990-07-25 |
| NZ212023A (en) | 1988-04-29 |
| KR870000274B1 (ko) | 1987-02-23 |
| EP0161918A2 (en) | 1985-11-21 |
| EP0161918A3 (en) | 1986-11-20 |
| PT80414A (en) | 1985-06-01 |
| ES8609308A1 (es) | 1986-09-01 |
| SU1486060A3 (ru) | 1989-06-07 |
| GR851121B (pm) | 1985-11-25 |
| KR850008166A (ko) | 1985-12-13 |
| JPH0643417B2 (ja) | 1994-06-08 |
| AU4240585A (en) | 1985-11-21 |
| MY101520A (en) | 1991-11-30 |
| DK207785A (da) | 1985-11-15 |
| JPS6122080A (ja) | 1986-01-30 |
| ES543078A0 (es) | 1986-09-01 |
| ATE54915T1 (de) | 1990-08-15 |
| PT80414B (en) | 1987-04-16 |
| ZA853440B (en) | 1986-12-30 |
| AU577372B2 (en) | 1988-09-22 |
| DK207785D0 (da) | 1985-05-10 |
| PH21862A (en) | 1988-03-25 |
| DE3578822D1 (de) | 1990-08-30 |
| IL75122A (en) | 1989-02-28 |
| HU194873B (en) | 1988-03-28 |
| CA1248099A (en) | 1989-01-03 |
| HUT37783A (en) | 1986-02-28 |
| IL75122A0 (en) | 1985-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUT35639A (en) | Process for preparing 3-chloro-1-formyl-4-phenyl-pyrrole derivatives | |
| EG17342A (en) | A process for preparing indoline and 2-indelinone derivatives | |
| HUT38941A (en) | Process for preparing triazolo-quinazoline derivatives | |
| HUT38093A (en) | Process for preparing benzene-sulphonamide derivatives | |
| HUT40431A (en) | Process for preparing piperidine derivatives | |
| YU62385A (en) | Process for obtaining 9a-aza-9a-homoeritromicyn derivatives | |
| HUT38317A (en) | Process for preparing ethylene-diamino-monoamide derivatives | |
| HUT41715A (en) | Process for preparing n-substituted alpha-aminoacids and derivatives thereof | |
| HUT42441A (en) | Process for preparing indolyl- and indazolyl-carboxamide derivatives | |
| HUT41012A (en) | Process for preparing cinnoline derivatives | |
| HUT42500A (en) | New process for preparing sphyngosine derivatives | |
| HUT38604A (en) | Process for preparing fluoro-alkyl-amine derivatives | |
| HUT38333A (en) | Process for preparing 1-piperidino-2-phenyl-quinoline derivatives | |
| HUT40114A (en) | Process for preparing flavolignane derivatives | |
| EP0208040A3 (en) | Rhodanine derivatives and a process for preparing same | |
| HUT37755A (en) | Process for preparing dihydropyridine derivatives | |
| RO93563B (ro) | Procedeu de preparare a unor derivati de 3-fenoxifenil-propen-1-il-ciclopropan | |
| HUT37757A (en) | Process for preparing 2-substituted-5-methyl-pyridina derivatives | |
| PT81988A (en) | Process for preparing novel alkylamino-furanone derivatives | |
| GB2157287B (en) | Process for preparing 3-exomethylenecepham derivatives | |
| DE3560592D1 (en) | A process for the preparation of l-tryptophan | |
| IL76816A0 (en) | Process for preparing 13-hydroxy-5-ketomilbemycin derivatives and 5-ketomilbemycin derivatives utilizable therein | |
| HUT42432A (en) | Process for preparing substituted phenyl-carbamide derivatives | |
| GB2168978B (en) | Process for preparing pyrrolidine derivatives | |
| PT80643A (en) | Process for preparing nitroethenamina derivatives |