ES2037230T3 - Composiciones activadoras de la penetracion. - Google Patents

Composiciones activadoras de la penetracion.

Info

Publication number
ES2037230T3
ES2037230T3 ES198888307752T ES88307752T ES2037230T3 ES 2037230 T3 ES2037230 T3 ES 2037230T3 ES 198888307752 T ES198888307752 T ES 198888307752T ES 88307752 T ES88307752 T ES 88307752T ES 2037230 T3 ES2037230 T3 ES 2037230T3
Authority
ES
Spain
Prior art keywords
parts
weight
compositions
penetration
activating compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888307752T
Other languages
English (en)
Inventor
Kirti Himatlal Valia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of ES2037230T3 publication Critical patent/ES2037230T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

SE DESCRIBEN UNA SERIE DE COMPUESTOS POTENCIADORES DE LA PERMEABILIDAD. DICHOS COMPUESTOS CONTIENEN ENTRE 30 Y 70% PARTES EN PESO DE ETANOL, 0.1 A 10 PARTES EN PESO DE AZONA, 30 A 80 PARTE EN PESO DE AGUA Y OPCIONALMENTE DE 10 A 30 PARTES EN PESO DE PROPILENGLICOL, Y FAVORECERAN UNA MAYOR ABSORCION PERCUTANEA DEL AGENTE FARMACOLOGICAMENTE ACTIVO ADMINISTRADO CON ELLAS.
ES198888307752T 1987-08-28 1988-08-22 Composiciones activadoras de la penetracion. Expired - Lifetime ES2037230T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9072687A 1987-08-28 1987-08-28

Publications (1)

Publication Number Publication Date
ES2037230T3 true ES2037230T3 (es) 1993-06-16

Family

ID=22224021

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888307752T Expired - Lifetime ES2037230T3 (es) 1987-08-28 1988-08-22 Composiciones activadoras de la penetracion.

Country Status (12)

Country Link
EP (1) EP0306192B1 (es)
JP (1) JPS6471821A (es)
AT (1) ATE76584T1 (es)
AU (1) AU613077B2 (es)
DE (1) DE3871464D1 (es)
DK (1) DK472188A (es)
ES (1) ES2037230T3 (es)
GR (1) GR3004877T3 (es)
HU (1) HU204692B (es)
NZ (1) NZ225907A (es)
PH (1) PH24913A (es)
ZA (1) ZA886218B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196410A (en) * 1986-10-31 1993-03-23 Pfizer Inc. Transdermal flux enhancing compositions
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
JP2815179B2 (ja) * 1989-07-14 1998-10-27 千寿製薬株式会社 抗炎症および／または抗アレルギー剤
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
EP0491076A1 (en) * 1990-12-19 1992-06-24 Theratech, Inc. Penetration enhancement with multi-component system of N-aliphatic pyrrolidones with lower alcohols
TW304167B (es) * 1995-01-30 1997-05-01 Lilly Co Eli

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405616A (en) * 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
US4501980A (en) * 1982-06-04 1985-02-26 Motornetics Corporation High torque robot motor
US4557934A (en) * 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
ZA853440B (en) * 1984-05-14 1986-12-30 Lilly Co Eli Indoline and 2-indolinone derivatives
JPH0627074B2 (ja) * 1984-07-25 1994-04-13 日東電工株式会社 医薬組成物
JPH06104624B2 (ja) * 1986-05-07 1994-12-21 太郎 小木曽 経皮吸収剤
MY102980A (en) * 1986-10-31 1993-03-31 Pfizer Transdermal flux enhancing compositions

Also Published As

Publication number Publication date
EP0306192A2 (en) 1989-03-08
GR3004877T3 (es) 1993-04-28
EP0306192B1 (en) 1992-05-27
AU613077B2 (en) 1991-07-25
PH24913A (en) 1990-12-26
DK472188A (da) 1989-03-31
JPS6471821A (en) 1989-03-16
EP0306192A3 (en) 1989-06-07
DK472188D0 (da) 1988-08-24
HUT52964A (en) 1990-09-28
DE3871464D1 (de) 1992-07-02
AU2150988A (en) 1989-03-02
HU204692B (en) 1992-02-28
NZ225907A (en) 1990-05-28
ATE76584T1 (de) 1992-06-15
ZA886218B (en) 1990-04-25

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