FI872231A - Vaetskehaltiga steroidformulationer foer intranasal dosering. - Google Patents

Vaetskehaltiga steroidformulationer foer intranasal dosering. Download PDF

Info

Publication number
FI872231A
FI872231A FI872231A FI872231A FI872231A FI 872231 A FI872231 A FI 872231A FI 872231 A FI872231 A FI 872231A FI 872231 A FI872231 A FI 872231A FI 872231 A FI872231 A FI 872231A
Authority
FI
Finland
Prior art keywords
amount
intranasal
steroidformulationer
dosering
foer
Prior art date
Application number
FI872231A
Other languages
English (en)
Other versions
FI88459C (fi
FI872231A0 (fi
FI88459B (fi
Inventor
Eric Joel Benjamin
Shabbir Tyabji Anik
Ya-Yun Tracy Lin
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of FI872231A0 publication Critical patent/FI872231A0/fi
Publication of FI872231A publication Critical patent/FI872231A/fi
Application granted granted Critical
Publication of FI88459B publication Critical patent/FI88459B/fi
Publication of FI88459C publication Critical patent/FI88459C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI872231A 1986-05-22 1987-05-21 Foerfarande foer framstaellning av en foer intranasal applikation laemplig steroidkomposition FI88459C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/866,171 US4782047A (en) 1986-05-22 1986-05-22 Aqueous steroid formulations for nasal administration
US86617186 1986-05-22

Publications (4)

Publication Number Publication Date
FI872231A0 FI872231A0 (fi) 1987-05-21
FI872231A true FI872231A (fi) 1987-11-23
FI88459B FI88459B (fi) 1993-02-15
FI88459C FI88459C (fi) 1993-05-25

Family

ID=25347059

Family Applications (1)

Application Number Title Priority Date Filing Date
FI872231A FI88459C (fi) 1986-05-22 1987-05-21 Foerfarande foer framstaellning av en foer intranasal applikation laemplig steroidkomposition

Country Status (19)

Country Link
US (1) US4782047A (fi)
EP (1) EP0246652B1 (fi)
JP (1) JP2521291B2 (fi)
KR (1) KR950008308B1 (fi)
AT (1) ATE65183T1 (fi)
AU (1) AU609718B2 (fi)
CA (1) CA1288048C (fi)
DE (1) DE3771389D1 (fi)
DK (1) DK175238B1 (fi)
ES (1) ES2031467T3 (fi)
FI (1) FI88459C (fi)
GR (1) GR3002317T3 (fi)
HK (1) HK39094A (fi)
IE (1) IE60259B1 (fi)
IL (1) IL82615A (fi)
IT (1) IT1205667B (fi)
NO (1) NO173365C (fi)
NZ (1) NZ220394A (fi)
ZA (1) ZA873663B (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983595A (en) * 1986-05-22 1991-01-08 Syntex (U.S.A.) Inc. Aqueous steroid formulations for nasal administration
JPH0311016A (ja) * 1989-06-09 1991-01-18 Tokyo Tanabe Co Ltd ピリド［１，２―ａ］ピリミジン誘導体の水性製剤
GB9103824D0 (en) * 1991-02-23 1991-04-10 Fisons Ag Formulation
US5338732A (en) * 1991-06-18 1994-08-16 Bristol-Myers Squibb Company Megestrol acetate formulation
US5789375A (en) * 1993-10-21 1998-08-04 Hisamitsu Pharmaceutical Co., Inc. Pernasal composition and pernasal preparation containing the same
US5762917A (en) * 1994-09-27 1998-06-09 Virotex Corporation Method and composition for cleansing wounds with minimal cytotoxicity for minimal scarring
US5976573A (en) * 1996-07-03 1999-11-02 Rorer Pharmaceutical Products Inc. Aqueous-based pharmaceutical composition
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
US8466134B1 (en) 1998-06-26 2013-06-18 Athena Neurosciences, Inc. Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
GB9918559D0 (en) * 1999-08-07 1999-10-06 Glaxo Wellcome Kk Novel pharmaceutical formulation
US20060083691A1 (en) * 2000-05-10 2006-04-20 Wermeling Daniel P Intranasal opioid compositions, delivery devices and methods of using same
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
US6610271B2 (en) * 2000-05-10 2003-08-26 University Of Kentucky Research Foundation System and method for intranasal administration of lorazepam
US6948492B2 (en) 2000-08-15 2005-09-27 University Of Kentucky Research Foundation Programmable multi-dose intranasal drug delivery device
US20040176359A1 (en) * 2001-02-20 2004-09-09 University Of Kentucky Research Foundation Intranasal Benzodiazepine compositions
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
WO2004012662A2 (en) 2002-08-01 2004-02-12 Aesgen, Inc. Improved treatment of cancer with glutamine
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US7404489B1 (en) 2003-03-04 2008-07-29 Qol Medical, Llc Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
JP4632687B2 (ja) * 2003-04-25 2011-02-16 ロート製薬株式会社 点鼻剤
JP5238779B2 (ja) * 2003-04-25 2013-07-17 ロート製薬株式会社 点鼻剤
WO2005065185A2 (en) * 2003-12-24 2005-07-21 Collegium Pharmaceuticals, Inc. Temperature-stable formulations, and methods of development thereof
GB0400804D0 (en) 2004-01-14 2004-02-18 Innoscience Technology Bv Pharmaceutical compositions
US20060045850A1 (en) * 2004-08-30 2006-03-02 Qpharma, Llc Nasal delivery of cyclodextrin complexes of anti-inflammatory steroids
ES2704482T3 (es) 2004-11-24 2019-03-18 Meda Pharmaceuticals Inc Composiciones que comprenden azelastina y sus métodos de uso
JP2009504767A (ja) * 2005-08-17 2009-02-05 フレミング・アンド・カンパニー・ファーマシューティカルズ ビタミンｂ１２鼻用スプレーおよび使用方法
KR100767976B1 (ko) 2006-08-25 2007-10-18 한국유나이티드제약 주식회사 비내 건조증에 효과적인 약제학적 조성물
ES2611995T3 (es) 2007-01-19 2017-05-11 Hananja Ehf Métodos y composiciones para el suministro de un agente terapéutico
US20080275030A1 (en) 2007-01-19 2008-11-06 Sveinbjorn Gizurarson Methods and Compositions for the Delivery of a Therapeutic Agent
JP2011001317A (ja) * 2009-06-19 2011-01-06 Fumakilla Ltd 鼻用洗浄剤
AU2014233362A1 (en) * 2013-03-15 2015-10-01 Medicis Pharmaceutical Corporation Topical compositions of flunisolide and methods of treatment
US11135155B2 (en) 2014-07-08 2021-10-05 Hikma Pharmaceuticals Usa Inc. Liquid naloxone spray
JP6097787B2 (ja) * 2015-06-09 2017-03-15 パル ファーマシューティカル， インコーポレーテッド 鼻内送達用シアノコバラミン低粘度水性製剤
US11510859B2 (en) 2015-07-16 2022-11-29 Marinomed Biotech Ag Method for improving aqueous solubility of water-insoluble or slightly water-soluble drugs
JP6836825B2 (ja) 2015-07-16 2021-03-03 マリノメド ビオテヒ エージー 水不溶性またはわずかに水溶性の薬剤の水可溶性を改善するための方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2989437A (en) * 1955-06-08 1961-06-20 Upjohn Co Anti-inflammatory and anti-bacterial decongestant nasal spray compositions
MX3864E (es) * 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
US4444762A (en) * 1980-04-04 1984-04-24 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclopentan-2-ones
US4344940A (en) * 1981-11-30 1982-08-17 E. R. Squibb & Sons, Inc. Steroid formulation containing dipotassium EDTA
US4603131A (en) * 1982-04-26 1986-07-29 Bernstein Joel E Method and composition for treating and preventing irritation of the mucous membranes of the nose

Also Published As

Publication number Publication date
HK39094A (en) 1994-04-29
IE60259B1 (en) 1994-06-29
KR950008308B1 (ko) 1995-07-27
EP0246652A3 (en) 1988-02-03
DK258687A (da) 1987-11-23
ATE65183T1 (de) 1991-08-15
NZ220394A (en) 1990-04-26
AU609718B2 (en) 1991-05-09
NO872127D0 (no) 1987-05-21
DK175238B1 (da) 2004-07-19
FI88459C (fi) 1993-05-25
IL82615A (en) 1991-11-21
IE871335L (en) 1987-11-22
AU7327387A (en) 1987-11-26
FI872231A0 (fi) 1987-05-21
KR870010862A (ko) 1987-12-18
DE3771389D1 (de) 1991-08-22
ZA873663B (en) 1988-12-28
JP2521291B2 (ja) 1996-08-07
EP0246652B1 (en) 1991-07-17
IT1205667B (it) 1989-03-31
IL82615A0 (en) 1987-11-30
FI88459B (fi) 1993-02-15
CA1288048C (en) 1991-08-27
JPS62283927A (ja) 1987-12-09
ES2031467T3 (es) 1992-12-16
GR3002317T3 (en) 1992-12-30
NO872127L (no) 1987-11-23
NO173365B (no) 1993-08-30
US4782047A (en) 1988-11-01
DK258687D0 (da) 1987-05-21
EP0246652A2 (en) 1987-11-25
NO173365C (no) 1993-12-08
IT8720621A0 (it) 1987-05-21

Similar Documents

Publication Publication Date Title
FI872231A0 (fi) Vaetskehaltiga steroidformulationer foer intranasal dosering.
EP0313303A3 (en) Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent
RU93047799A (ru) Композиции, содержащие ретиноевые кислоты и токоферол
EP0313304A3 (en) Photoprotection compositions comprising tocopherol sorbate
FI933740A0 (fi) Peg-interferonkonjugat
DE3381396D1 (de) Formulierung nicht irritierender ophthalmischer waesseriger zusammensetzungen fuer okular-therapeutische mittel.
EP0313302A3 (en) Photoprotection compositions comprising sorbohydroxamic acid
DE69226491D1 (de) Verbesserung der Durchdringungfähigkeit von topischen Anwendbaren Formulierungen
ES2032898T5 (es) Locion de esteroide.
ATE63220T1 (de) Transdermal resorbierbare, wasserhaltige zubereitungen von arylpropionsaeurederivaten und verfahren zur herstellung derselben.
ZA91115B (en) Topical compositions
AU4040195A (en) Topical composition containing penciclovir
IL76393A (en) Stable parenteral aqueous pharmaceutical compositions of dezocine

Legal Events

Date Code Title Description
FG Patent granted

Owner name: SYNTEX PHARMACEUTICALS INTERNATIONAL

BB Publication of examined application
FG Patent granted

Owner name: SYNTEX PHARMACEUTICALS INTERNATIONAL

MA Patent expired