IL76393A - Stable parenteral aqueous pharmaceutical compositions of dezocine - Google Patents

Stable parenteral aqueous pharmaceutical compositions of dezocine

Info

Publication number
IL76393A
IL76393A IL76393A IL7639385A IL76393A IL 76393 A IL76393 A IL 76393A IL 76393 A IL76393 A IL 76393A IL 7639385 A IL7639385 A IL 7639385A IL 76393 A IL76393 A IL 76393A
Authority
IL
Israel
Prior art keywords
dezocine
pharmaceutical compositions
aqueous pharmaceutical
vol
percent
Prior art date
Application number
IL76393A
Other versions
IL76393A0 (en
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of IL76393A0 publication Critical patent/IL76393A0/en
Publication of IL76393A publication Critical patent/IL76393A/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B61RAILWAYS
    • B61KAUXILIARY EQUIPMENT SPECIALLY ADAPTED FOR RAILWAYS, NOT OTHERWISE PROVIDED FOR
    • B61K9/00Railway vehicle profile gauges; Detecting or indicating overheating of components; Apparatus on locomotives or cars to indicate bad track sections; General design of track recording vehicles
    • B61K9/08Measuring installations for surveying permanent way
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Laminated Bodies (AREA)
  • Saccharide Compounds (AREA)

Abstract

Ready-to-use parenteral formulations of dezocine contain from about 0,2 to about 2,0 percent wt/vol. dezocine; about 30 to about 45 percent wt/vol. propylene glycol; about 0,5 to about 2,0 percent wt/vol. lactic acid; buffered with a pharmaceutically acceptable base to a pH of from about 3,5 to about 5,0 and 0 to about 0,02 percent wt/vol. sodium or potassium metabisulphite, in water for injection.
IL76393A 1984-09-28 1985-09-13 Stable parenteral aqueous pharmaceutical compositions of dezocine IL76393A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65597684A 1984-09-28 1984-09-28

Publications (2)

Publication Number Publication Date
IL76393A0 IL76393A0 (en) 1986-01-31
IL76393A true IL76393A (en) 1988-06-30

Family

ID=24631145

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76393A IL76393A (en) 1984-09-28 1985-09-13 Stable parenteral aqueous pharmaceutical compositions of dezocine

Country Status (20)

Country Link
US (1) US4605671A (en)
EP (1) EP0180303B1 (en)
JP (1) JPH0621060B2 (en)
KR (1) KR890000905B1 (en)
AT (1) ATE41602T1 (en)
AU (1) AU572689B2 (en)
CA (1) CA1251402A (en)
CY (1) CY1511A (en)
DE (1) DE3568942D1 (en)
DK (1) DK165439C (en)
GB (1) GB2165149B (en)
HK (1) HK19990A (en)
HU (1) HU197667B (en)
IE (1) IE58139B1 (en)
IL (1) IL76393A (en)
MY (1) MY102521A (en)
NZ (1) NZ213573A (en)
PH (1) PH20498A (en)
SG (1) SG71489G (en)
ZA (1) ZA856680B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8802564D0 (en) * 1988-07-08 1988-07-08 Astra Ab NEW SYNERGISTIC PREPARATIONS AND A NEW METHOD OF ALLEVIATION OF PAIN
IT1302682B1 (en) 1998-10-16 2000-09-29 Formenti Farmaceutici Spa ORAL PHARMACEUTICAL COMPOSITIONS CONTAINING BUPRENORPHINE
CN104523584B (en) * 2014-12-22 2018-03-30 扬子江药业集团有限公司 A kind of injection of dezocine and preparation method thereof
CN106880586A (en) * 2015-12-16 2017-06-23 天津泰普药品科技发展有限公司 A kind of preparation method of the dezocine injection of stabilization
CN110483315B (en) * 2018-05-15 2021-11-09 扬子江药业集团有限公司 Preparation method of dezocine impurity C

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150147A (en) * 1978-03-24 1979-04-17 American Home Products Corporation Stimulation of prolactin release by an aminotetralin analgesic

Also Published As

Publication number Publication date
MY102521A (en) 1992-07-31
DK438785A (en) 1986-03-29
CA1251402A (en) 1989-03-21
EP0180303A1 (en) 1986-05-07
KR890000905B1 (en) 1989-04-13
IL76393A0 (en) 1986-01-31
US4605671A (en) 1986-08-12
GB2165149A (en) 1986-04-09
KR860002269A (en) 1986-04-24
NZ213573A (en) 1988-07-28
GB8521303D0 (en) 1985-10-02
GB2165149B (en) 1988-05-25
EP0180303B1 (en) 1989-03-22
ATE41602T1 (en) 1989-04-15
PH20498A (en) 1987-01-21
SG71489G (en) 1990-03-02
IE852117L (en) 1986-03-28
DK165439B (en) 1992-11-30
AU572689B2 (en) 1988-05-12
DK438785D0 (en) 1985-09-27
AU4713685A (en) 1986-04-10
DE3568942D1 (en) 1989-04-27
JPH0621060B2 (en) 1994-03-23
ZA856680B (en) 1987-04-29
HUT39359A (en) 1986-09-29
HU197667B (en) 1989-05-29
CY1511A (en) 1990-08-03
HK19990A (en) 1990-03-23
IE58139B1 (en) 1993-07-14
JPS6185314A (en) 1986-04-30
DK165439C (en) 1993-04-19

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Legal Events

Date Code Title Description
KB Patent renewed
HCA Change of name of proprietor(s) after amalgamation
KB Patent renewed
EXP Patent expired