EG12982A - Pyrimido(6,1-a)isoquinolin-2-one derivatives - Google Patents
Pyrimido(6,1-a)isoquinolin-2-one derivativesInfo
- Publication number
- EG12982A EG12982A EG680/77A EG68077A EG12982A EG 12982 A EG12982 A EG 12982A EG 680/77 A EG680/77 A EG 680/77A EG 68077 A EG68077 A EG 68077A EG 12982 A EG12982 A EG 12982A
- Authority
- EG
- Egypt
- Prior art keywords
- pyrimido
- isoquinolin
- derivatives
- Prior art date
Links
- ZYAUPWZSCSJSNL-UHFFFAOYSA-N C=1C(N=CN2C1C1=CC=CC=C1C=C2)=O Chemical class C=1C(N=CN2C1C1=CC=CC=C1C=C2)=O ZYAUPWZSCSJSNL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650905—Six-membered rings having the nitrogen atoms in the positions 1 and 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772720085 DE2720085A1 (de) | 1977-05-05 | 1977-05-05 | Pyrimido(6,1-a)isochinolin-2-on- derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EG12982A true EG12982A (en) | 1982-03-31 |
Family
ID=6008073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EG680/77A EG12982A (en) | 1977-05-05 | 1977-12-10 | Pyrimido(6,1-a)isoquinolin-2-one derivatives |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4482556A (pt) |
| JP (2) | JPS53137997A (pt) |
| AT (1) | AT372383B (pt) |
| BE (1) | BE862785A (pt) |
| CH (2) | CH640854A5 (pt) |
| DK (2) | DK158789C (pt) |
| EG (1) | EG12982A (pt) |
| ES (3) | ES464776A1 (pt) |
| FI (1) | FI64370C (pt) |
| FR (1) | FR2389623B1 (pt) |
| GR (1) | GR72114B (pt) |
| IL (1) | IL53336A (pt) |
| IT (1) | IT1192252B (pt) |
| NL (1) | NL185078C (pt) |
| NO (2) | NO148032C (pt) |
| PT (1) | PT67265B (pt) |
| SE (2) | SE436357B (pt) |
| ZA (1) | ZA776706B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2847693A1 (de) * | 1978-11-03 | 1980-05-22 | Hoechst Ag | Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen |
| FR2470130A2 (fr) * | 1979-11-21 | 1981-05-29 | Hoechst Ag | Derives de pyrimido (6,1-a) isoquinoleine-4-one, leur procede de preparation et leur application en therapeutique |
| DE3135831A1 (de) * | 1981-09-10 | 1983-04-28 | Hoechst Ag, 6230 Frankfurt | 9,10-substituierte 2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2h-pyrimido(6,1-a)isochinolin-4-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| CA1237429A (en) * | 1983-05-05 | 1988-05-31 | Frank Kienzle | Pyrimidone derivatives |
| DE3816995A1 (de) * | 1988-05-19 | 1989-11-23 | Hoechst Ag | Verwendung von pyrimido-(6,1-a)-isochinolin-4-on-derivaten und medizinische zubereitungen auf basis dieser verbindungen |
| DE68902811D1 (de) * | 1988-11-19 | 1992-10-15 | Hoechst Ag | Pharmazeutische zusammensetzungen mit einem gehalt an labdan-di-terpenoid-derivaten und pyrimido(6,1-a)isochinolin-4-on-derivaten und ihre anwendung. |
| CN100415743C (zh) * | 1999-03-31 | 2008-09-03 | 韦尔纳利斯有限公司 | 嘧啶并[6,1-a] 异喹啉-4-酮衍生物 |
| WO2005007092A2 (en) * | 2003-07-08 | 2005-01-27 | Smithkline Beecham Corporation | Novel chemical compounds |
| CN101671336B (zh) | 2009-09-23 | 2013-11-13 | 辽宁利锋科技开发有限公司 | 芳杂环并嘧啶衍生物和类似物及其制备方法和用途 |
| GB201613054D0 (en) | 2016-07-28 | 2016-09-14 | Verona Pharma Plc | New compound and process |
| IL280075B2 (en) * | 2018-07-13 | 2024-06-01 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | A conjugated tricyclic compound as a dual PDE3/PDE4 inhibitor |
| JP2023512471A (ja) * | 2020-01-15 | 2023-03-27 | チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッド | Ｐｄｅ３／ｐｄｅ４二重阻害剤の結晶及びその使用 |
| AU2021208129A1 (en) * | 2020-01-15 | 2022-08-18 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Pharmaceutical composition of tricyclic PDE3/PDE4 dual inhibitor compound |
| JP2024517583A (ja) * | 2021-04-29 | 2024-04-23 | ▲蘇▼州盛迪▲亞▼生物医▲薬▼有限公司 | イソキノリノン系化合物及びその用途 |
| WO2024088402A1 (zh) * | 2022-10-28 | 2024-05-02 | 江苏恒瑞医药股份有限公司 | 一种异喹啉酮类化合物的晶型及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3021331A (en) * | 1959-07-20 | 1962-02-13 | Pfizer & Co C | Azabenzopyridocolines |
| US3081306A (en) * | 1959-11-04 | 1963-03-12 | Pfizer & Co C | 2, 4-dioxo-3-aralkylaza-9, 10-di(lower alkoxy)-1, 2, 3, 4, 6, 7-hexahydro-11b-h-benzopyridocolines |
| US3297696A (en) * | 1965-05-28 | 1967-01-10 | Sandoz Ag | 6-amino-8, 9-dihydro-13bh-isoquinolo-[2, 1-c] quinazolines and intermediates therefor |
| DE2126148A1 (en) * | 1971-05-26 | 1972-12-07 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Prepn of uracil derivs - useful as plant - protection agents and their inters |
| DE2847693A1 (de) * | 1978-11-03 | 1980-05-22 | Hoechst Ag | Verfahren zur herstellung von pyrimido-(6,1-a)-isochinolin-2-onen |
| US5740368A (en) * | 1995-06-30 | 1998-04-14 | Canon Kabushiki Kaisha | Method and apparatus for providing information on a managed peripheral device to plural agents |
-
1977
- 1977-11-02 FI FI773286A patent/FI64370C/fi not_active IP Right Cessation
- 1977-11-03 DK DK489477A patent/DK158789C/da active
- 1977-11-03 AT AT0784477A patent/AT372383B/de active
- 1977-11-04 SE SE7712513A patent/SE436357B/sv not_active IP Right Cessation
- 1977-11-08 IL IL53336A patent/IL53336A/xx unknown
- 1977-11-09 ZA ZA00776706A patent/ZA776706B/xx unknown
- 1977-11-11 PT PT67265A patent/PT67265B/pt unknown
- 1977-11-19 JP JP13845577A patent/JPS53137997A/ja active Granted
- 1977-12-02 NO NO774131A patent/NO148032C/no unknown
- 1977-12-06 ES ES464776A patent/ES464776A1/es not_active Expired
- 1977-12-10 EG EG680/77A patent/EG12982A/xx active
-
1978
- 1978-01-01 CH CH1331977A patent/CH640854A5/de not_active IP Right Cessation
- 1978-01-05 NL NLAANVRAGE7800149,A patent/NL185078C/xx not_active IP Right Cessation
- 1978-01-10 BE BE184225A patent/BE862785A/xx not_active IP Right Cessation
- 1978-02-02 FR FR7802935A patent/FR2389623B1/fr not_active Expired
- 1978-03-14 GR GR55702A patent/GR72114B/el unknown
- 1978-04-21 IT IT22619/78A patent/IT1192252B/it active
- 1978-08-16 ES ES472606A patent/ES472606A1/es not_active Expired
- 1978-10-19 CH CH1084178A patent/CH642949A5/de not_active IP Right Cessation
- 1978-11-13 ES ES475027A patent/ES475027A1/es not_active Expired
-
1980
- 1980-03-26 US US06/134,080 patent/US4482556A/en not_active Expired - Lifetime
-
1982
- 1982-04-19 NO NO821266A patent/NO821266L/no unknown
- 1982-11-19 SE SE8206619A patent/SE439307B/sv not_active IP Right Cessation
-
1984
- 1984-06-18 JP JP59123892A patent/JPS6041677A/ja active Granted
- 1984-09-19 US US06/652,005 patent/US4598148A/en not_active Expired - Lifetime
-
1989
- 1989-06-01 DK DK267089A patent/DK267089D0/da not_active Application Discontinuation
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