ECSP21069105A - Anticuerpos anti-trem2 y métodos para utilizarlos - Google Patents
Anticuerpos anti-trem2 y métodos para utilizarlosInfo
- Publication number
- ECSP21069105A ECSP21069105A ECSENADI202169105A ECDI202169105A ECSP21069105A EC SP21069105 A ECSP21069105 A EC SP21069105A EC SENADI202169105 A ECSENADI202169105 A EC SENADI202169105A EC DI202169105 A ECDI202169105 A EC DI202169105A EC SP21069105 A ECSP21069105 A EC SP21069105A
- Authority
- EC
- Ecuador
- Prior art keywords
- trem2
- methods
- trem2 antibodies
- antibodies
- antibody
- Prior art date
Links
- 101000795117 Homo sapiens Triggering receptor expressed on myeloid cells 2 Proteins 0.000 abstract 3
- 102100029678 Triggering receptor expressed on myeloid cells 2 Human genes 0.000 abstract 3
- 230000004913 activation Effects 0.000 abstract 1
- 230000007423 decrease Effects 0.000 abstract 1
- 210000000066 myeloid cell Anatomy 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962808141P | 2019-02-20 | 2019-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP21069105A true ECSP21069105A (es) | 2021-11-18 |
Family
ID=69844940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSENADI202169105A ECSP21069105A (es) | 2019-02-20 | 2021-09-17 | Anticuerpos anti-trem2 y métodos para utilizarlos |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20220073609A1 (enExample) |
| EP (1) | EP3927743A1 (enExample) |
| JP (2) | JP7543290B2 (enExample) |
| KR (1) | KR20210135518A (enExample) |
| CN (1) | CN113614110B (enExample) |
| AR (1) | AR118144A1 (enExample) |
| AU (1) | AU2020226754A1 (enExample) |
| BR (1) | BR112021015656A2 (enExample) |
| CA (1) | CA3130086A1 (enExample) |
| CL (1) | CL2021002206A1 (enExample) |
| CO (1) | CO2021012230A2 (enExample) |
| EA (1) | EA202192294A1 (enExample) |
| EC (1) | ECSP21069105A (enExample) |
| IL (1) | IL285651A (enExample) |
| MA (1) | MA55025A (enExample) |
| MX (1) | MX2021009722A (enExample) |
| PE (1) | PE20211979A1 (enExample) |
| PH (1) | PH12021552002A1 (enExample) |
| SG (1) | SG11202108734VA (enExample) |
| TW (1) | TWI879756B (enExample) |
| WO (2) | WO2020172457A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20190248A1 (ar) | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
| KR20210111785A (ko) * | 2018-12-18 | 2021-09-13 | 베링거 잉겔하임 아이오 캐나다 인크. | Flt3 항진제 항체 및 이의 용도 |
| WO2020172457A1 (en) | 2019-02-20 | 2020-08-27 | Denali Therapeutics Inc. | Anti-trem2 antibodies and methods of use thereof |
| AU2021208482B2 (en) | 2020-01-13 | 2025-12-11 | Denali Therapeutics Inc. | Anti-TREM2 antibodies and methods of use thereof |
| BR112023023777A2 (pt) * | 2021-05-14 | 2024-01-30 | Genentech Inc | Anticorpos isolados, composição farmacêutica, ácido nucleico isolado, vetor isolado, célula hospedeira isolada, método para produzir um anticorpo, método para tratar uma condição associada à perda de função de trem2, método para reduzir os níveis de strem2 e uso de um anticorpo |
| MX2024010324A (es) | 2022-02-23 | 2024-08-30 | Alector Llc | Metodos de uso de anticuerpos anti-trem2. |
| EP4499693A1 (en) | 2022-03-28 | 2025-02-05 | Denali Therapeutics Inc. | Monovalent anti-trem2 binding molecules and methods of use thereof |
| WO2023192282A1 (en) | 2022-03-28 | 2023-10-05 | Denali Therapeutics Inc. | Methods for treating brain glucose hypometabolism |
| CN120603851A (zh) | 2023-01-30 | 2025-09-05 | 伊萨尔生物科学有限责任公司 | 用于治疗神经退行性疾病的人抗trem2抗体 |
| WO2025032071A1 (en) | 2023-08-09 | 2025-02-13 | F. Hoffmann-La Roche Ag | Mono and multispecific anti-trem2 antibodies, methods and uses thereof |
| WO2025032069A1 (en) | 2023-08-09 | 2025-02-13 | F. Hoffmann-La Roche Ag | Mono and multispecific anti-trem2 antibodies, methods and uses thereof |
| TW202515919A (zh) | 2023-09-01 | 2025-04-16 | 比利時商艾托斯比利時公司 | 抗ｔｒｅｍ２抗體及使用方法 |
| WO2025106361A1 (en) * | 2023-11-15 | 2025-05-22 | Merck Sharp & Dohme Llc | Human nectin-4 binders |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8231878B2 (en) | 2001-03-20 | 2012-07-31 | Cosmo Research & Development S.P.A. | Receptor trem (triggering receptor expressed on myeloid cells) and uses thereof |
| US8981061B2 (en) | 2001-03-20 | 2015-03-17 | Novo Nordisk A/S | Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof |
| US20120016112A1 (en) | 2009-01-06 | 2012-01-19 | Nestec S.A. | Processing of macronutrients |
| RU2015132478A (ru) | 2009-03-05 | 2015-12-10 | Эббви Инк. | Связывающие il-17 белки |
| US10087408B2 (en) | 2010-07-07 | 2018-10-02 | The University Of British Columbia | System and method for microfluidic cell culture |
| US9188593B2 (en) | 2010-07-16 | 2015-11-17 | The University Of British Columbia | Methods for assaying cellular binding interactions |
| CN103781800A (zh) * | 2011-06-20 | 2014-05-07 | 协和发酵麒麟株式会社 | 抗erbB3抗体 |
| PT3677591T (pt) | 2013-04-29 | 2023-02-17 | Teva Pharmaceuticals Australia Pty Ltd | Anticorpos anti-cd38 e fusões a interferão alfa-2b atenuado |
| CA2922979A1 (en) | 2013-09-03 | 2015-03-12 | Novimmune S.A. | Readily isolated bispecific binding molecules with native format having mutated constant regions |
| CN105218669A (zh) | 2014-06-10 | 2016-01-06 | 河北翰林生物科技有限公司 | 制备抗人r47h-trem2突变体的人单克隆抗体的方法 |
| SG10201913611QA (en) * | 2014-08-08 | 2020-03-30 | Alector Llc | Anti-trem2 antibodies and methods of use thereof |
| US10428143B2 (en) | 2014-09-28 | 2019-10-01 | The Regents Of The University Of California | Modulation of stimulatory and non-stimulatory myeloid cells |
| CN107207579B (zh) * | 2015-03-31 | 2022-02-25 | 豪夫迈·罗氏有限公司 | 包含三聚体tnf家族配体的抗原结合分子 |
| WO2017058866A1 (en) * | 2015-09-28 | 2017-04-06 | Precision Immune, Inc. | Anti-trem2 antibodies and uses thereof |
| EP3359569A2 (en) * | 2015-10-06 | 2018-08-15 | Alector LLC | Anti-trem2 antibodies and methods of use thereof |
| WO2017147509A1 (en) | 2016-02-25 | 2017-08-31 | Marco Colonna | Compositions comprising trem2 and methods of use thereof |
| WO2017189959A1 (en) | 2016-04-29 | 2017-11-02 | Voyager Therapeutics, Inc. | Compositions for the treatment of disease |
| US10941200B2 (en) | 2016-07-22 | 2021-03-09 | Deutsches Zentrum Für Neurodegenerative Erkrankungen Ev | TREM2 cleavage modulators and uses thereof |
| CN110121507B (zh) | 2016-12-23 | 2024-04-05 | 蓝鳍生物医药公司 | 抗sez6l2抗体和抗体药物缀合物 |
| US20190367623A1 (en) | 2017-01-17 | 2019-12-05 | Yeda Research And Development Co. Ltd. | Methods of treating neurodegenerative diseases by inducing disease-associated microglia (dam) cells |
| HUE060983T2 (hu) | 2017-02-17 | 2023-05-28 | Denali Therapeutics Inc | Mesterségesen elõállított transferrin receptort kötõ polipeptidek |
| CN110520440A (zh) | 2017-02-17 | 2019-11-29 | 戴纳立制药公司 | 抗τ抗体及其使用方法 |
| US10457717B2 (en) | 2017-02-17 | 2019-10-29 | Denali Therapeutics Inc. | Engineered polypeptides |
| JOP20190248A1 (ar) * | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
| AU2018307877A1 (en) | 2017-07-27 | 2020-01-02 | Novartis Ag | Sheddase resistant TREM2 variants |
| TW202511296A (zh) | 2017-08-03 | 2025-03-16 | 美商阿列克特有限責任公司 | 抗trem2抗體及其使用方法 |
| RS64584B1 (sr) | 2017-08-10 | 2023-10-31 | Denali Therapeutics Inc | Konstruisani polipeptidi koji se vezuju za transferinski receptor |
| CA3075285A1 (en) | 2017-09-14 | 2019-03-21 | Denali Therapeutics Inc. | Anti-trem2 antibodies and methods of use thereof |
| US20200277584A1 (en) | 2017-10-02 | 2020-09-03 | Denali Therapeutics Inc. | Fusion proteins comprising enzyme replacement therapy enzymes |
| US20210186917A1 (en) | 2017-10-17 | 2021-06-24 | The Translational Genomics Research Institute | Trem2 agonists for the stimulation of microglia and methods of identification |
| WO2019094608A1 (en) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anti-bace1 antibodies and methods of use thereof |
| IL321287A (en) | 2017-12-12 | 2025-08-01 | Pionyr Immunotherapeutics Inc | Anti-trem2 antibodies and related methods |
| KR102720600B1 (ko) | 2018-01-10 | 2024-10-21 | 데날리 테라퓨틱스 인크. | 트랜스페린 수용체-결합 폴리펩타이드 및 이의 용도 |
| US20210284702A1 (en) | 2018-06-18 | 2021-09-16 | Denali Therapeutics Inc. | Fusion proteins comprising progranulin |
| GB201811404D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Anti-CD137 Antibodies |
| AU2019320803A1 (en) | 2018-08-16 | 2021-03-11 | Denali Therapeutics Inc. | Engineered bispecific proteins |
| BR112021002953A2 (pt) | 2018-08-22 | 2021-05-11 | Denali Therapeutics Inc. | polipeptídeos anti-her2 e métodos de uso dos mesmos |
| US12145988B2 (en) | 2018-09-11 | 2024-11-19 | Washington University | Anti-TREM-2 agonist antibodies |
| UY38407A (es) | 2018-10-15 | 2020-05-29 | Novartis Ag | Anticuerpos estabilizadores de trem2 |
| KR102156165B1 (ko) | 2018-10-29 | 2020-09-15 | 재단법인대구경북과학기술원 | 인간 ｔｒｅｍ２ 세포막 단백질에 대한 단일클론항체, 이를 생산하는 하이브리도마 세포주 및 이의 용도 |
| US20230132366A9 (en) | 2018-11-26 | 2023-04-27 | Denali Therapeutics Inc. | Methods for treating dysregulated lipid metabolism |
| MA54450A (fr) | 2018-12-10 | 2021-10-20 | Denali Therapeutics Inc | Biomarqueurs de maladie lysosomale et leurs méthodes d'utilisation |
| EP3898691A4 (en) | 2018-12-10 | 2022-09-14 | Mor Research Applications | TREM2 ANTIBODIES AND THEIR USES |
| AU2019397479A1 (en) | 2018-12-11 | 2021-07-29 | Pionyr Immunotherapeutics, Inc. | Methods of using anti-TREM2 antibodies |
| WO2020172457A1 (en) | 2019-02-20 | 2020-08-27 | Denali Therapeutics Inc. | Anti-trem2 antibodies and methods of use thereof |
| WO2020194317A1 (en) | 2019-03-28 | 2020-10-01 | Yeda Research And Development Co. Ltd. | Method of treating lipid-related disorders |
| AU2020252554A1 (en) | 2019-04-03 | 2021-10-28 | Denali Therapeutics Inc. | Formulations of protein molecules comprising iduronate 2-sulfatase |
| JP2023507846A (ja) | 2019-12-23 | 2023-02-27 | デナリ セラピューティクス インコーポレイテッド | プログラニュリン変異体 |
| TWI890727B (zh) | 2020-01-13 | 2025-07-21 | 美商戴納立製藥公司 | 抗trem2 抗體及其使用方法 |
| AU2021208482B2 (en) | 2020-01-13 | 2025-12-11 | Denali Therapeutics Inc. | Anti-TREM2 antibodies and methods of use thereof |
| US20230092681A1 (en) | 2020-02-07 | 2023-03-23 | Denali Therapeutics Inc. | Methods for the treatment of hunter syndrome |
| EP4181950A4 (en) | 2020-02-19 | 2024-07-17 | Denali Therapeutics Inc. | Engineered anti-her2 bispecific proteins |
| CR20230178A (es) | 2020-10-14 | 2023-07-26 | Denali Therapeutics Inc | Proteínas de fusión que comprenden enzimas sulfoglucosamina sulfohidrolasa y métodos de estas |
-
2020
- 2020-02-20 WO PCT/US2020/019104 patent/WO2020172457A1/en not_active Ceased
- 2020-02-20 AU AU2020226754A patent/AU2020226754A1/en active Pending
- 2020-02-20 KR KR1020217028927A patent/KR20210135518A/ko active Pending
- 2020-02-20 EP EP20711737.5A patent/EP3927743A1/en active Pending
- 2020-02-20 MX MX2021009722A patent/MX2021009722A/es unknown
- 2020-02-20 CA CA3130086A patent/CA3130086A1/en active Pending
- 2020-02-20 JP JP2021548668A patent/JP7543290B2/ja active Active
- 2020-02-20 SG SG11202108734VA patent/SG11202108734VA/en unknown
- 2020-02-20 MA MA055025A patent/MA55025A/fr unknown
- 2020-02-20 BR BR112021015656-9A patent/BR112021015656A2/pt unknown
- 2020-02-20 PE PE2021001367A patent/PE20211979A1/es unknown
- 2020-02-20 WO PCT/US2020/019093 patent/WO2020172450A1/en not_active Ceased
- 2020-02-20 AR ARP200100461A patent/AR118144A1/es unknown
- 2020-02-20 PH PH1/2021/552002A patent/PH12021552002A1/en unknown
- 2020-02-20 TW TW109105560A patent/TWI879756B/zh active
- 2020-02-20 CN CN202080015804.2A patent/CN113614110B/zh active Active
- 2020-02-20 EA EA202192294A patent/EA202192294A1/ru unknown
-
2021
- 2021-08-16 US US17/403,406 patent/US20220073609A1/en not_active Abandoned
- 2021-08-16 US US17/402,986 patent/US12240902B2/en active Active
- 2021-08-16 IL IL285651A patent/IL285651A/en unknown
- 2021-08-18 CL CL2021002206A patent/CL2021002206A1/es unknown
- 2021-09-17 CO CONC2021/0012230A patent/CO2021012230A2/es unknown
- 2021-09-17 EC ECSENADI202169105A patent/ECSP21069105A/es unknown
-
2024
- 2024-08-21 JP JP2024139367A patent/JP2024164116A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020172457A1 (en) | 2020-08-27 |
| AR118144A1 (es) | 2021-09-22 |
| PH12021552002A1 (en) | 2022-09-19 |
| PE20211979A1 (es) | 2021-10-05 |
| MA55025A (fr) | 2021-12-29 |
| CN113614110A (zh) | 2021-11-05 |
| AU2020226754A1 (en) | 2021-09-16 |
| BR112021015656A2 (pt) | 2021-10-05 |
| CL2021002206A1 (es) | 2022-04-22 |
| CO2021012230A2 (es) | 2021-09-30 |
| US20220119522A1 (en) | 2022-04-21 |
| JP7543290B2 (ja) | 2024-09-02 |
| CA3130086A1 (en) | 2020-08-27 |
| IL285651A (en) | 2021-09-30 |
| CN113614110B (zh) | 2025-03-25 |
| WO2020172450A1 (en) | 2020-08-27 |
| US20220073609A1 (en) | 2022-03-10 |
| JP2022520868A (ja) | 2022-04-01 |
| KR20210135518A (ko) | 2021-11-15 |
| EA202192294A1 (ru) | 2021-12-24 |
| TW202045543A (zh) | 2020-12-16 |
| MX2021009722A (es) | 2021-09-14 |
| JP2024164116A (ja) | 2024-11-26 |
| TWI879756B (zh) | 2025-04-11 |
| SG11202108734VA (en) | 2021-09-29 |
| EP3927743A1 (en) | 2021-12-29 |
| US12240902B2 (en) | 2025-03-04 |
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