ECSP099513A - Nuevos compuestos y sus efectos sobre el conductismo de la alimentación - Google Patents
Nuevos compuestos y sus efectos sobre el conductismo de la alimentaciónInfo
- Publication number
- ECSP099513A ECSP099513A EC2009009513A ECSP099513A ECSP099513A EC SP099513 A ECSP099513 A EC SP099513A EC 2009009513 A EC2009009513 A EC 2009009513A EC SP099513 A ECSP099513 A EC SP099513A EC SP099513 A ECSP099513 A EC SP099513A
- Authority
- EC
- Ecuador
- Prior art keywords
- glu17
- glu15
- tyr21 phe22
- lys20 tyr21
- gln24
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
La invención provee un péptido que comprende la secuencia de amino ácido que se da a continuación, conjuntamente con los usos del péptido y los métodos asociados con los mismos. El péptido es particularmente útil como supresor del apetito y para el tratamiento de la obesidad. Xaa1 Xaa2 Xaa3 Gly4 Thr5 Phe6 Thr7 Ser8 Asp9 Tyr10 Ser11 Lys12 Tyr13 Leu14 Xaa15 Xaa16 Xaa17 Xaa18 Xaa19 Xaa20 Xaa21 Xaa22 Xaa23 Xaa24 Trp25 Leu26 Xaa27 Xaa28 Xaa29 Xaa30 Xaa31 Xaa32 Lys33 Asn34 Asn35 Ile36 Ala37; donde: Xaa1 es His1 o D-His1, Xaa2 es Ser2 o Ala2, Xaa3 es Gln3 o Asp3; Xaa15 Xaa16 Xaa17 Xaa18 Xaa19 Xaa20 Xaa21 Xaa22 Xaa23 Xaa24 es: Glu15 Glu16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Leu23 Glu24, Glu15 Glu16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Leu23 Gln24, Glu15 Glu16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Ile23 Glu24, Glu15 Glu16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Ile23 Gln24, Glu15 Glu16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Leu23 Glu24, Glu15 Glu16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Leu23 Gln24, Glu15 Glu16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Ile23 Glu24, Glu15 Glu16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Ile23 Gln24, Glu15 Gln16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Leu23 Glu24, Glu15 Gln16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Leu23 Gln24, Glu15 Gln16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Ile23 Glu24, Glu15 Gln16 Glu17 Leu18 Val19 Lys20 Tyr21 Phe22 Ile23 Gln24, Glu15 Gln16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Leu23 Glu24, Glu15 Gln16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Leu23 Gln24, Glu15 Gln16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Ile23 Glu24, Glu15 Gln16 Glu17 Ile18 Val19 Lys20 Tyr21 Phe22 Ile23 Gln24, o Asp15 Ser16 Arg17 Arg18 Ala19 Gln20 Asp21 Phe22 Val23 Gln24; Xaa27 Xaa28 Xaa29 Xaa30 Xaa31 Xaa32 es: Met27 Asn28 Thr29 Lys30 Arg31 Asn32, Lys27 Asn28 Ala29 Gly30 Pro31 Ser32, o Lys27 Asn28 Gly29 Gly30 Pro31 Ser32 o un péptido tal como se indicó anteriormente en el cual el residuo Asn34 es reemplazado con Asp34; o un péptido tal como se indicó anteriormente en el cual Xaa3 es Glu3; con la condición de que si Xaa15 Xaa16 Xaa17 Xaa18 Xaa19 Xaa20 Xaa21 Xaa22 Xaa23 Xaa24 es Asp15 Ser16 Arg17 Arg18 Ala19 Gln20 Asp21 Phe22 Val23 Gln24, entonces Xaa27 Xaa28 Xaa29 Xaa30 Xaa31 Xaa32 no es Met27 Asn28 Thr29 Lys30 Arg31 Asn32
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0624868.6A GB0624868D0 (en) | 2006-12-13 | 2006-12-13 | Novel compounds and their effects on feeding behaviour |
GB0625667A GB0625667D0 (en) | 2006-12-21 | 2006-12-21 | Novel compounds and their effects on feeding behaviour |
GB0700897A GB0700897D0 (en) | 2007-01-17 | 2007-01-17 | Novel compounds and their effects on feeding behaviour |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP099513A true ECSP099513A (es) | 2009-08-28 |
Family
ID=39106277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2009009513A ECSP099513A (es) | 2006-12-13 | 2009-07-13 | Nuevos compuestos y sus efectos sobre el conductismo de la alimentación |
Country Status (22)
Country | Link |
---|---|
US (3) | US8101576B2 (es) |
EP (2) | EP1985304A3 (es) |
JP (1) | JP5669395B2 (es) |
KR (1) | KR20090098843A (es) |
AR (1) | AR064334A1 (es) |
AU (1) | AU2007331257B2 (es) |
BR (1) | BRPI0721093A2 (es) |
CA (1) | CA2672406A1 (es) |
CO (1) | CO6210830A2 (es) |
CR (1) | CR10923A (es) |
EC (1) | ECSP099513A (es) |
GT (1) | GT200900163A (es) |
IL (1) | IL199247A (es) |
MX (1) | MX2009006348A (es) |
MY (1) | MY152840A (es) |
NI (1) | NI200900116A (es) |
NZ (1) | NZ578213A (es) |
RU (1) | RU2492183C2 (es) |
SG (1) | SG177226A1 (es) |
SV (1) | SV2009003297A (es) |
TW (1) | TWI428346B (es) |
WO (1) | WO2008071972A1 (es) |
Families Citing this family (85)
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- 2007-12-13 JP JP2009540858A patent/JP5669395B2/ja not_active Expired - Fee Related
- 2007-12-13 WO PCT/GB2007/004779 patent/WO2008071972A1/en active Application Filing
- 2007-12-13 MX MX2009006348A patent/MX2009006348A/es active IP Right Grant
- 2007-12-13 KR KR1020097013317A patent/KR20090098843A/ko not_active Application Discontinuation
- 2007-12-13 SG SG2011095585A patent/SG177226A1/en unknown
- 2007-12-13 AU AU2007331257A patent/AU2007331257B2/en not_active Ceased
- 2007-12-13 RU RU2009126634/04A patent/RU2492183C2/ru not_active IP Right Cessation
- 2007-12-13 EP EP07254859A patent/EP1985304A3/en not_active Withdrawn
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- 2007-12-13 US US11/956,266 patent/US8101576B2/en not_active Expired - Fee Related
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- 2009-06-11 SV SV2009003297A patent/SV2009003297A/es not_active Application Discontinuation
- 2009-06-12 GT GT200900163A patent/GT200900163A/es unknown
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- 2009-07-13 CR CR10923A patent/CR10923A/es unknown
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2011
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CA2672406A1 (en) | 2008-06-19 |
JP2010513256A (ja) | 2010-04-30 |
AU2007331257B2 (en) | 2013-06-27 |
MX2009006348A (es) | 2009-06-30 |
RU2009126634A (ru) | 2011-01-20 |
US20090181885A1 (en) | 2009-07-16 |
CR10923A (es) | 2009-11-09 |
KR20090098843A (ko) | 2009-09-17 |
JP5669395B2 (ja) | 2015-02-12 |
US20150018289A1 (en) | 2015-01-15 |
MY152840A (en) | 2014-11-28 |
CO6210830A2 (es) | 2010-10-20 |
US8101576B2 (en) | 2012-01-24 |
WO2008071972A1 (en) | 2008-06-19 |
AR064334A1 (es) | 2009-04-01 |
NZ578213A (en) | 2012-04-27 |
AU2007331257A1 (en) | 2008-06-19 |
TWI428346B (zh) | 2014-03-01 |
IL199247A (en) | 2014-04-30 |
EP2422808A3 (en) | 2012-06-13 |
SV2009003297A (es) | 2010-02-17 |
SG177226A1 (en) | 2012-01-30 |
TW200827370A (en) | 2008-07-01 |
BRPI0721093A2 (pt) | 2014-02-11 |
EP2422808A2 (en) | 2012-02-29 |
NI200900116A (es) | 2010-06-22 |
RU2492183C2 (ru) | 2013-09-10 |
EP1985304A2 (en) | 2008-10-29 |
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US20130089545A1 (en) | 2013-04-11 |
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