ECSP024392A - Analogos de peptido-1 del tipo glucagon - Google Patents
Analogos de peptido-1 del tipo glucagonInfo
- Publication number
- ECSP024392A ECSP024392A ECSP024392A ECSP024392A EC SP024392 A ECSP024392 A EC SP024392A EC SP024392 A ECSP024392 A EC SP024392A EC SP024392 A ECSP024392 A EC SP024392A
- Authority
- EC
- Ecuador
- Prior art keywords
- glp
- glu
- asp
- ala
- lys
- Prior art date
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un compuesto GLP-1 que comprende la secuencia de aminoácidos de fórmula 1 (SEQ ID No. 1) His-Xaa8-Glu-Gly-Xaa11-Xaa12-Thr-Ser-asp-Xaa16-Ser-Ser-Tyr-Leu-Glu-Xaa22-Xaa23-Xaa24-Ala-Xaa27-Phe-Ile-Ala-Xaa31-Leu-Xaa33-Xaa34-Xaa35-Xaa36-R . Fórmula I (SEQ ID No:1) en la que: Xaa8 es: Gly, Ala, Val, Leu, Ile, Ser o Thr; Xaa11 es: Asp, Glu, Arg, Thr, Ala, Lys o His; Xaa12 es: His, Trp, Phe o Tyr; Xaa16 es: Leu, Ser, Thr, Trp, His, Phe, Asp, Val, Tyr, Glu, o Ala; Xaa22 es: Gly, Asp, Glu, Gln, Asn, Lys, Arg, Cys o ácido cisteico; Xaa23 es: His, Asp, Lys, Glu, Gln o Arg; Xaa24 es: Glu, Arg, Ala o Lys; Xaa26 es; Trp, Tyr, Phe, Asp, Lys, Glu o His; Xaa27 es: Ala, Glu, His, Phe, Tyr, Trp, Arg o Lys; Xaa30 es: Ala, Glu, Asp, Ser o His; Xaa33 es: Asp, Arg, Val, Lys, Ala, Gly o Glu; Xaa34 es: Glu, Lys o Asp; Xaa35 es: Tbr, Ser, Lys, Arg, Trp, Tyr, Phe, Asp, Gly, Pro, His o Glu; Xaa36 es: Tbr, Ser, Asp, Trp, Tyr, Phe, Arg, Glu o His; R es: Lys, Arg, Tbr, Ser, Glu, Asp, Txp, Tyr, Phe, His, - NH2, Gly, Gly-Pro o Gly-Pro-Nh2 o no aparece. con la condición de que el compuesto GLP-1 no tenga la secuencia de GLP-1 (7-37) OH o GLP-1 (7-36) NH2 y, con tal de que el compuesto GLP-1 no sea Gly8-GLP.-1(7-37)OH, Gly8-GLP-1(7-36)NH2, Val8-GLP1-(7-37)OHM Leu8-GLP-1(7-36)NH2, Ile8-GLP-1(7-37)OH, Ile8-GLP-1(7-36NH2, Ser8- GLP-1(7-37)OH,Ser8-GLP1(7-36)NH2, Thr8-GLP-1(7-37)OH,o Thr8-GLP-1-(7-36)nh2, aLA11-glp-1(7-37)oh, aLA11-glp-1(7-36)NH2, Ala 16-GLP-1(7-37) OH, Ala16-GLP-1(7-36)NH2M ALA18-GLP-1(7-37)OH, Ala 18-GLP-1(7-36)NH2, Ala 27-GLP-1/7-37)OH, Ala27,-GLP-1(7-36)NH2, Ala33-GLP-(7-37) OH, Ala33-GLP-1(7-36NH2.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21217100P | 2000-06-16 | 2000-06-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP024392A true ECSP024392A (es) | 2003-02-06 |
Family
ID=32849305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP024392 ECSP024392A (es) | 2000-06-16 | 2002-12-13 | Analogos de peptido-1 del tipo glucagon |
Country Status (3)
| Country | Link |
|---|---|
| EC (1) | ECSP024392A (es) |
| UA (1) | UA88862C2 (es) |
| ZA (1) | ZA200210098B (es) |
-
2001
- 2001-06-01 UA UA20021210090A patent/UA88862C2/ru unknown
-
2002
- 2002-12-12 ZA ZA200210098A patent/ZA200210098B/en unknown
- 2002-12-13 EC ECSP024392 patent/ECSP024392A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200210098B (en) | 2004-03-12 |
| UA88862C2 (en) | 2009-12-10 |
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